Clinical trials: Coronary Artery Bypass Surgery
Kidney Failure, Chronic, Coronary Artery Disease
Prophylactic Effect of Nifedipine on Further Decline in Renal Function in Patients Undergoing Open-Heart Surgery
To compare renal function (51Cr-EDTA clearance) 48 hours post open-heart surgery (coronary bypass or valve surgery) in patients with impaired renal function after randomization to either nifedipine infusion at start of surgery…
- Trial name
- NCT00244530
- Testing
- Nifedipine
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- University of Oslo School of Pharmacy
Myocardial Infarction
Autologous Bone Marrow Derived Stem Cells for Acute Myocardial Infarction
One of the important reasons for human dying is Ischemic heart disease (IHD). The most reason is coronary artery disease. Beside morbidity, IHD induce myocardial infarction and necrosis which due to congestive heart failure.
- Trial name
- NCT01167751
- Testing
- MNC, AC 133, Control
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Royan Institute
Coronary Artery Disease, Postoperative Complications
Anesthesia Management of Coronary Artery Bypass Surgery and Inflammatory Biomarkers
The goal of this observational study is to evaluate effect of total intravenous anesthesia or inhalation anesthesia on inflammatory biomarkers in coronary artery bypass surgery and their relationship with early postoperative…
- Conditions
- Coronary Artery Disease, Postoperative Complications, Anesthesia
- Trial name
- NCT06209437
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people
- Sponsor
- Ankara City Hospital Bilkent
Coronary Artery Disease
Effects of Glutamine in Ischemic Heart Disease Patients Following Cardiopulmonary Bypass
The purpose of this study is to determine whether perioperative glutamine administration possess protective properties on internal organs (heart and gut) in patients with coronary atherosclerosis, operated under cardiopulmonary…
- Trial name
- NCT01478126
- Testing
- N(2)-L-Alanine L-Glutamine dipeptide
- Where
- Russia
- Volunteers
- 24 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Frail Elderly, Coronary Artery Disease
Off-pump Versus On-pump Coronary Artery Bypass Grafting in Frail Patients
Frailty is defined as a geriatric syndrome of impaired resiliency to stressors (such as cardiac surgery) that has been delineated recently in the cardiovascular literature.
- Trial name
- FRAGILE (NCT02338947)
- Testing
- Off-pump coronary-artery bypass grafting, On-pump coronary-artery bypass grafting
- Where
- 7 sites in United States, Brazil
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Coronary Artery Bypass Graft, Radial Artery Grafts
Different Anti-Spastic Therapy Strategies After CABG Using Radial Artery Grafts
The Pilot study will be a single-center, randomized, open-label, active-controlled trial. After CABG surgery using Radial Artery Grafts (RA-CABG) and signing the informed consent, all patients will be screened according to the…
- Conditions
- Coronary Artery Bypass Graft, Radial Artery Grafts, Antispastic Therapy, Pilot Study
- Trial name
- ASRAB-Pilot (NCT04310995)
- Testing
- Nicorandil 5mg tid, Diltiazem 180mg qd, Isosorbide Mononitrate 50mg qd
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Ruijin Hospital
Heart Defects, Congenital, Hypertension, Pulmonary
Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery
This clinical trial will determine the safety and effectiveness of intravenous L-citrulline in children undergoing cardiopulmonary bypass during heart surgery.
- Trial name
- NCT00335244
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Asklepion Pharmaceuticals, LLC
Patient Depression, Anxiety, Stress and Pain
The Effect of Listening to Holy Quran Recital on Depression, Anxiety and Stress Post CABG
Coronary artery bypass graft (CABG) is one of the most common surgical treatments for coronary artery disease. CABG has many beneficial outcomes for patients.
- Trial name
- NCT05419544
- Testing
- Holy Quran Recital effect
- Where
- 2 sites in Jordan
- Volunteers
- 128 people
- Sponsor
- Applied Science Private University
Coronary Artery Bypass Graft (CABG)
Investigation of the Effect of Prehabilitation Practice on Patient Outcomes in Frail Patients Planned for Elective Coronary Artery Bypass Graft
The basic concept of prehabilitation is to increase the functional capacity of the individual to withstand an expected injury. It embodies the idea of being proactive against the common reactive approach of rehabilitation.
- Trial name
- ERAS (NCT07138534)
- Testing
- prehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bahçeşehir University
Cardiac Denervation, Postoperative Atrial Fibrillation
A New Way of Cardiac Denervation to Reduce the Incidence of AF After CABG.
This is a prospective, random controlled trial(RCT) study. 430 patients undergoing coronary artery bypass grafting were enrolled.
- Trial name
- NCT05009914
- Testing
- cardiac denervation
- Where
- China
- Volunteers
- 430 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Bypass Surgery
Computed Tomography Coronary Angiography in Patients With a Previous Coronary Artery Bypass Graft Surgery Trial
This randomized, multi-center, prospective study seeks to compare the conventional invasive Coronary Angiography with the recently described method of performing CT-Coronary Angiography prior to the invasive Coronary Angiography…
- Trial name
- GREECE (NCT04631809)
- Testing
- Coronary angiography +/- percutaneous coronary intervention, CT-Coronary Angiography + Coronary angiography +/- percutaneous coronary intervention
- Where
- Greece
- Volunteers
- 225 people
- Sponsor
- University Hospital of Patras
Coronary Artery Bypass Graft CABG
Effect of Early Mobilization Exercises After Coronary Artery Bypass Graft
purpose: This study aims to assess the effects of early mobilization exercises guided by wearable technology on functional capacity after coronary artery bypass graft Methods: Patients will be randomly assigned into three groups…
- Trial name
- NCT06801314
- Testing
- aerobic exercise using cycle ergometer in addition to usual care, resisted exercise using weights and dumbbells in addition to usual care, usual care using mobilization and breathing exercise
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Cairo University
Coronary Artery Bypass Graft Surgery
Cardiac CAtheterization for Bypass Graft Patency Rate Optimization: the CABG-PRO Randomized-controlled Pilot Study
Aortocoronary bypass graft failure is common and is associated with high morbidity and mortality. Failure of saphenous vein grafts is more common than failure of internal mammary artery grafts.
- Trial name
- CABG-PRO (NCT01063491)
- Testing
- bypass graft angiography
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- North Texas Veterans Healthcare System
Cardiovascular Disease
Usefulness of Integrative Medicine Tools As Adjunctive Care for Women After Coronary Artery Bypass Grafting
Background: This randomized controlled trial investigates the effectiveness of an Integrative Therapies (IT) health education intervention in improving physical and psychological functioning in female patients after coronary…
- Trial name
- NCT01020227
- Testing
- Integrative Therapies Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Columbia University
Surgery
Effectiveness of Animation-Based Education Given to Elderly Patients Undergoing Coronary Artery Bypass Graft Surgery
It was conducted to measure the effectiveness of animation-based training given to elderly patients who will undergo coronary artery bypass graft surgery on the patients' pain, fear, anxiety and self-care management.
- Trial name
- NCT06928025
- Testing
- Preoperative Education
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ayşegül Sena Pirgaip Yavuz
Heart Diseases, Coronary Artery Disease
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
The central hypothesis of ROMA:Women is that the use of multiple arterial grafting (MAG) will improve clinical outcomes and quality of life (QOL) compared to single arterial grafting (SAG).
- Conditions
- Heart Diseases, Coronary Artery Disease, Coronary Artery Bypass Grafting
- Trial name
- ROMA:Women (NCT04124120)
- Testing
- Single arterial graft, Multiple arterial grafting
- Where
- 146 sites in United States, Australia and 24 more
- Volunteers
- 2,300 people
- Sponsor
- Weill Medical College of Cornell University
Obesity, Morbid
ECG Triggered Dual Source CT for Non-invasive Pre-operative Cardiac Imaging in Morbid Obese Patients
Coronary arterial disease is a risk factor for bariatric surgery and might be a predictor for later major adverse coronary events.
- Trial name
- NCT02802579
- Testing
- standard protocol, enhanced protocol, enhanced obesity protocol
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- Cantonal Hospital of St. Gallen
Coronary Artery Bypass
A Retrospective Analysis of the Predictive Potential of Pre-operative
Roughly thirty percent of people that undergo open heart surgery get an abnormal heart beat afterwards known as atrial fibrillation (AF).
- Trial name
- NCT00321282
- Testing
- Atrial Fibrillation
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- Emory University
Chronic Total Occlusion of Coronary Artery
A Prospective, First in Man Study to Evaluate the Safety and Performance of the NovaCross™ Micro-catheter
This is a prospective, non-randomized, first-in-man investigational study, to assess the safety and technical feasibility, deployment and withdrawal characteristics of the NovaCross™ micro-catheter during an interventional…
- Trial name
- NCT01978860
- Testing
- NovaCross, CTO
- Where
- Israel
- Volunteers
- 2 people
- Sponsor
- Chanan Schneider
Acute Kidney Injury (AKI), Coronary Artery Bypass Graft (CABG)
Effect of Cardiovascular Autonomic Neuropathy on AKI and Outcomes in Isolated CABG Surgery
This study aims to investigate the effects of Cardiovascular Autonomic Neuropathy (CAN) on Acute Kidney Injury (AKI) and clinical outcomes in patients undergoing isolated Coronary Artery Bypass Graft (CABG) surgery requiring…
- Conditions
- Acute Kidney Injury (AKI), Coronary Artery Bypass Graft (CABG), Cardiovascular Autonomic Neuropathy (CAN), Postoperative Outcomes
- Trial name
- CAN-AKI-CABG (NCT07254468)
- Where
- Turkey (Türkiye)
- Volunteers
- 912 people
- Sponsor
- Akdeniz University
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