Clinical trials: Coronary Artery Bypass Surgery
Coronary Artery Disease, End Stage Renal Disease
Coronary Revascularization in Patients On Dialysis in China-Retrospective Registry
Coronary artery disease (CAD) is the leading cause of death in end-stage renal disease (ESRD) patients requiring dialysis. There are limited data on clinical characteristics, treatment strategies and outcomes in this special…
- Conditions
- Coronary Artery Disease, End Stage Renal Disease, Dialysis
- Trial name
- CRUISE-R (NCT05841082)
- Where
- China
- Volunteers
- 1,249 people
- Sponsor
- China-Japan Friendship Hospital
Cardiac Surgery
A Registry Study on Serumal Biomarkers About Adverse Events in Patients Undergoing Coronary Artery Bypass Grafting.
This is a national registry study to determine the serumal biomarkers for prognosis of adverse events in patients undergoing coronary artery bypass grafting.
- Trial name
- ASBA-CABG (NCT04107571)
- Testing
- A type of operation for coranary heart disease patients.
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Percutaneous Coronary Intervention, Saphenous Vein
Short and Long-term Results of PCI in no Touch Vein-graft.
Coronary artery disease is one of the biggest health issue worldwide.The treatment, in a large part of the patients, implicates a so called bypass-operation, that consists in to connect new vascular conduits (grafts) beyond the…
- Conditions
- Percutaneous Coronary Intervention, Saphenous Vein, Coronary Artery Bypass
- Trial name
- NCT03999398
- Testing
- Percutaneous coronary intervention (PCI)
- Where
- Sweden
- Volunteers
- 260 people
- Sponsor
- Region Örebro County
Deep Vein Thrombosis, Coronary Artery Bypass Surgery
A Study of the Efficacy of Preventive Dosing of Fondaparinux Sodium Versus Placebo for the Prevention of Venous Thromboembolism (VTE) in Patients Undergoing Coronary Bypass Surgery Receiving Routine Mechanical Prophylaxis
This trial is a prospective, single-center Phase II randomized study to demonstrate the superior efficacy of Fondaparinux Sodium subcutaneous injections in patients undergoing CABG surgery (isolated and redo isolated) versus…
- Conditions
- Deep Vein Thrombosis, Coronary Artery Bypass Surgery, Venous Thromboembolism
- Trial name
- NCT00789399
- Testing
- Fondaparinux
- Volunteers
- 78 people
- Sponsor
- Prairie Education and Research Cooperative
Coronary Artery Bypass Graft, Median Sternotomy
Risk Factors of Sternal Wound Infection After Coronary Artery Bypass Graft
The investigators are trying to evaluate the performance of neutrophil and lymphocyte counts as a risk factor of deep sternal wound infection after coronary artery bypass graft surgery.
- Trial name
- NCT01629030
- Where
- South Korea
- Volunteers
- 1,850 people
- Sponsor
- Samsung Medical Center
Acute Myocardial Infarction: Rehabilitation Phase, Coronary Artery Bypass Graft Triple Vessel
Cardiopulmonary and Metabolic Responses to Early Exercise in Patients After Coronary Arterial Bypass Grafting
Coronary arterial bypass graft surgery (CABG) is proven safe with improved survival and greater quality of life in patients with coronary arterial disease.
- Conditions
- Acute Myocardial Infarction: Rehabilitation Phase, Coronary Artery Bypass Graft Triple Vessel, Physical Activity
- Trial name
- NCT02758600
- Testing
- Cycle ergometer exercise rehabilitation protocol
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Myocardial Infarction, Unstable Angina
Evaluation of an Introductory Videotape Intervention to Improve Cardiac Rehabilitation Participation
The purpose of this study is to determine whether a pre-discharge videotape introducing the concept and benefit of a Cardiac Rehabiliation \& Secondary Prevention (CRSP) program will increase intent to participate in a CRSP…
- Conditions
- Myocardial Infarction, Unstable Angina, Coronary Angioplasty, Coronary Artery Bypass Surgery
- Trial name
- NCT00372671
- Testing
- Survey, Survey and videotape
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Coronary Artery Disease
FiO2 and Outcomes After OPCAB (the CARROT Trial)
Conventionally, a relatively high level of fraction of inspired oxygen (FiO2) has been used for secure a margin of safety in patients undergoing cardiac surgery including off-pump coronary artery bypass grafting (OPCAB).
- Trial name
- NCT03945565
- Testing
- Fraction of inspired oxygen level
- Where
- South Korea
- Volunteers
- 414 people
- Sponsor
- Seoul National University Hospital
Aortocoronary Bypass
Randomized Trial of Pulsatile vs Non Pulsatile Perfusion on Short Term Changes in Kidney Function Using an Intra-Aortic Ballooon Pump During Cardioplegic Arrest in Patients Undergoing Myocardial Reperfusion
Linear flow during cardiopulmonary bypass (CPB) frequently induces renal damage. We will evaluate whether automatic intra-aortic balloon pump (IABP) induce pulsatile perfusion preserves renal function in patients undergoing…
- Trial name
- NCT00454428
- Testing
- pulsatile intra-aortic balloon pump
- Where
- Italy
- Sponsor
- University of Catanzaro
Coronary Artery Disease
Study to Evaluate the Safety and Efficacy of Humacyte's Coronary Tissue Engineered Vessel (CTEV) in Patients With Coronary Artery Disease Requiring Coronary Artery Bypass Grafting (CABG)
The goal of this study is to assess safety and efficacy of Humacyte's coronary tissue engineered vessel (CTEV) used as a bypass conduit in patients requiring multi vessel coronary artery bypass grafting (CABG).
- Trial name
- NCT07730528
- Testing
- Humacyte Coronary Tissue Engineered Vessel (CTEV)
- Volunteers
- 10 people
- Sponsor
- Humacyte, Inc.
Acquired Antithrombin III Deficiency, Coronary Artery Bypass
Use of Antithrombin in Cardiac Surgery With Cardiopulmonary Bypass
The purpose of this trial is to study the effects of preoperative antithrombin supplementation in patients undergoing cardiac surgery with cardiopulmonary bypass in order to maintain antithrombin levels in a range greater than…
- Trial name
- NCT00823082
- Testing
- Antithrombin III
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Instituto Grifols, S.A.
Cardiovascular Diseases, Cardiovascular Complication
The Effect Of Perioperative Results On Mortality In Coronary Artery Bypass Surgery
Coronary artery bypass grafting (CABG) is one of the most common heart surgeries. Most patients are elderly with comorbidities that affect morbidity and mortality rates. Even in developed countries mortality rate is 1.9-5.3%.
- Conditions
- Cardiovascular Diseases, Cardiovascular Complication, Anesthesia
- Trial name
- NCT06812624
- Testing
- There is no intervention in this study.
- Where
- Turkey (Türkiye)
- Volunteers
- 485 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Postoperative
Clinical Study of Depodur Efficacy in Decreasing Post Operative Pain After Off Pump Coronary Artery Bypass Grafting (OP-CABG)
The purpose of this study is to determine whether epidural Depodur alleviates the pain of OP-CABG surgery. This includes pain associated with sternotomy, retraction, dissection and other tissue insults, as well as the induced…
- Trial name
- NCT00456638
- Testing
- Depodur
- Sponsor
- Drexel University College of Medicine
Atrial Fibrillation
Homeopathy for Prevention of Atrial Fibrillation After Aortocoronary Bypass Surgery
After heart surgery, about 30% of patients suffer from atrial fibrillation. Patients are randomized into two groups receiving either potentized Strychnos Nux vomica or placebo under double blind conditions.
- Trial name
- NCT00861237
- Testing
- Nux vomica (active comparator)
- Where
- Austria
- Volunteers
- 12 people
- Sponsor
- Medical University of Vienna
Postoperative Pain, Regional Anaesthsia
Parasternal and Adductor Canal Blocks in CABG
This randomized controlled trial evaluates the effectiveness of different postoperative analgesic strategies in patients undergoing coronary artery bypass graft (CABG) surgery.
- Conditions
- Postoperative Pain, Regional Anaesthsia, Pain Management
- Trial name
- NCT07599748
- Testing
- parasternal block, Parasternal block + Adductor canal block, conventional analgesic regimen
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Zonguldak Bulent Ecevit University
Fluid Therapy, Coronary Artery Bypass Surgery Patients
Evaluation of Fluid Responsiveness With Recruitment Maneuver After Sternotomy in Coronary Artery Bypass Surgery
Assuming that the basic reliability of dynamic indices will increase with the application of functional hemodynamic tests after sternotomy and protective lung ventilation in patients undergoing elective coronary artery bypass…
- Conditions
- Fluid Therapy, Coronary Artery Bypass Surgery Patients, Lung Recruitment Maneuver
- Trial name
- fluidresponse (NCT06249568)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara City Hospital Bilkent
Sudden Cardiac Death, Ventricular Fibrillation
LifeVest Post-CABG Registry
This is a multi-center prospective registry of patients with an ejection fraction (EF) ≤ 35% following coronary artery bypass graft (CABG) surgery in order to test the hypothesis that wearable defibrillators (WD) will decrease…
- Conditions
- Sudden Cardiac Death, Ventricular Fibrillation, Ventricular Tachycardia, Ventricular Dysfunction
- Trial name
- NCT01448005
- Testing
- wearable defibrillator (LifeVest)
- Where
- 5 sites in United States
- Volunteers
- 69 people
- Sponsor
- Zoll Medical Corporation
Coronary Artery Bypass Grafting, Heart Valve Disease
LLM-Based Intelligent Health Management Assistant in Life-Cycle Health Management of Cardiac Surgery Patients
This is a single-center, prospective, randomized, open-label, parallel-controlled clinical study to evaluate the effectiveness of a large language model (LLM)-based intelligent health management assistant in the life-cycle health…
- Conditions
- Coronary Artery Bypass Grafting, Heart Valve Disease, Aortic Aneurysm, Aortic Dissection
- Trial name
- cFT-LLM (NCT07521488)
- Testing
- LLM-Based Intelligent Health Management Assistant
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Beijing Anzhen Hospital
Anemia
Effect of Arterial Oxygen Partial Pressure on Mixed Venous Oxygen Saturation
Mixed venous oxygen saturation is known to reflect oxygen delivery and, thus, is frequently monitored in patients undergoing cardiac surgery.
- Trial name
- NCT04144205
- Testing
- Change of the fraction of inspired oxygen
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Fatigue
Effects of Oral Iron on Postoperative Fatigue Upon Coronary Artery Bypass Graft Patients
The purpose of this research study is to examine how an oral iron supplement (Feramax®) influences fatigue during early postoperative recovery (at three months) among CABG patients and, the effects on recovery outcomes (e.g.
- Trial name
- NCT01912261
- Testing
- Polysaccharide iron complex
- Where
- Canada
- Volunteers
- 121 people
- Sponsor
- Nova Scotia Health Authority
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