Clinical trials: Coronary Artery Bypass Surgery
Myocardial Infarction
Venous Function in Cardiovascular Disease Patients
The primary aim is to determine the acute effect of two different training interventions on venous plasticity in patients with myocardial infarction (MI), revascularization or coronary artery graft surgery compared to age-matched…
- Trial name
- NCT01474408
- Testing
- interval training day 1, Moderate exercise day 2, Control day 3
- Where
- Norway
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Cardiac Output, Low
The Effects of Adrenaline and Milrinone in Patients With Myocardial Dysfunction After CABG
Myocardial dysfunction necessitating inotropic support is a typical complication after on-pump cardiac surgery. This prospective, randomized pilot-study analyses the metabolic and renal effects of the inotropes adrenaline and…
- Trial name
- AMORI (NCT00446017)
- Testing
- adrenaline, milrinone
- Volunteers
- 60 people
- Sponsor
- University of Luebeck
Coronary Artery Disease, Coronary Artery Bypass Graft
The Effects of Cardiac Rehabilitation on Sleep Quality and Sleep Duration in Patients After Coronary Artery Bypass Graft
This study aims to investigate the effects of cardiac rehabilitation on sleep quality and sleep duration in patients after coronary artery bypass graft.
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Graft, Sleep Quality, Cardiac Rehabilitation
- Trial name
- NCT05474339
- Testing
- Cardiac rehabilitation
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Atrial Fibrillation
Remote Ischemic Conditioning and Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG)
Recent studies indicate that remote ischemic conditioning can protect the heart and other organs during cardiac surgery. The investigators aim to investigate whether such a stimulus can reduce the incidence of atrial fibrillation…
- Trial name
- RICO (NCT01107184)
- Testing
- Remote ischemic conditioning
- Where
- Netherlands
- Volunteers
- 191 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Patients Waiting for Coronary Artery Bypass Graft Surgery, Patients Waiting for Aortic Valve Repair or Replacement
Pre-operative Rehabilitation for Reduction of Hospitalization After Coronary Bypass and Valvular Surgery.
The PREHAB study is a clinical trial where frail patients waiting for heart surgery are randomly chosen to either receive the current standard of care or to participate in an 8-week exercise/education program at a community-based…
- Conditions
- Patients Waiting for Coronary Artery Bypass Graft Surgery, Patients Waiting for Aortic Valve Repair or Replacement, Patients Waiting for Mitral Valve Repair or Replacement, Patients Waiting for Combined Procedures. (CAGB and Valve)
- Trial name
- PREHAB (NCT02219815)
- Testing
- Prehab Intervention
- Where
- 5 sites in Canada
- Volunteers
- 89 people
- Sponsor
- St. Boniface Hospital
Coronary Artery Bypass Graft Surgery
Peri-Operative Morbidity and Quality of Life After Coronary Artery Bypass Graft (CABG)
It is the long term objective of this study to preserve or improve the quality of life and to prevent deterioration in physical and mental function following myocardial revascularization among bypass surgery patients.
- Trial name
- NCT00248885
- Testing
- Regulating Mean Arterial Pressure during cardiopulmonary bypass
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Weill Medical College of Cornell University
Arrhythmia, Cardiovascular Diseases
Coronary Artery Bypass Graft (CABG) Patch Trial
To test the hypothesis that implantable cardioverter defibrillator (ICD) therapy will improve survival in coronary heart disease patients at high risk of death, especially arrhythmic death.
- Conditions
- Arrhythmia, Cardiovascular Diseases, Coronary Disease, Death, Sudden, Cardiac
- Trial name
- NCT00000540
- Testing
- defibrillators, implantable
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiac Disease, Surgery
Patient-centered and Clinical Outcomes After Minimally Invasive Cardiothoracic Surgery
Nowadays, minimally invasive cardiothoracic surgery techniques are being performed to treat patients with coronary heart diseases.
- Trial name
- NCT03902717
- Testing
- Minimally invasive cardiac surgery
- Where
- 2 sites in Belgium
- Volunteers
- 209 people
- Sponsor
- Jessa Hospital
Coronary Disease
A Study to Determine the Effect of Bi-Ventricular Pacing on Cardiac Hemodynamics After Coronary Artery Bypass Graft
The purpose of this study is to determine, using echocardiography, whether bi-ventricular pacing improves the contractile force by resynchronizing both ventricles, thereby improving and/or correcting the paradoxical septal…
- Trial name
- NCT00316368
- Testing
- Ethicon TPW32 60 cm (pacing wires x 2)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Unity Health Toronto
Coronary Artery Bypass, Arteriosclerosis
The SOS (Stenting Of Saphenous Vein Grafts) Trial
The main purpose of this study is to determine whether implantation of a paclitaxel-eluting stent (Taxus™) in saphenous vein graft lesions will reduce the incidence of in-stent restenosis after 12 months when compared to a…
- Trial name
- NCT00247208
- Testing
- Taxus polymer-based paclitaxel-eluting stent, Express 2 bare metal stent
- Where
- 5 sites in United States, Greece
- Volunteers
- 80 people
- Sponsor
- North Texas Veterans Healthcare System
Ischemic Cardiomyopathy
A Phase I Study of Allogeneic Myocardium-Derived Mesenchymal Stem Cells (HB1011) in Patients With Ischemic Cardiomyopathy
Ischemic cardiomyopathy occurs when the heart muscle is permanently weakened due to blocked coronary arteries that limit blood flow.
- Trial name
- HEART-1 (NCT07861035)
- Testing
- HB1011 (Allogeneic Myocardium-derived Mesenchymal Stem Cells)
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- HieraBio Inc.
Myocardial Bridge of Coronary Artery, Myocardial Bridge
Myocardialbridge Bypass Graft Surgery Efficacy Verification
Myocardial Bridge Bypass Graft surgery is introduced to relieve the unmedical symptoms of patients with long-segment or deep myocardial bridge, clinical outcomes will be collected to verify the effectiveness of the surgery.
- Conditions
- Myocardial Bridge of Coronary Artery, Myocardial Bridge, Myocardial Bridging, Myocardial Infarction
- Trial name
- NCT06857838
- Testing
- MBBG, MB CABG, MB unroof
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xi'an International Medical Center Hospital
Ischaemic Heart Disease
Trial of Rehabilitation in Phase 1 After Coronary Artery Bypass Grafting
Patients undergoing coronary artery bypass graft surgery often experience a range of problems and symptoms related to the procedure and the underlying heart disease.
- Trial name
- SheppHeart (NCT01941355)
- Testing
- Exercise training component, Psycho-educative component
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cardiac Surgery, Coronary Artery Bypass Grafting
Safety, Tolerability and Pharmacodynamics of AP214 Acetate in Patients Undergoing Cardiac Surgery
The purpose of the present research study is to investigate for the first time, the safety and tolerability of infusion doses of AP214 in subjects having heart surgery such as coronary bypass graft and/or valve repair or…
- Conditions
- Cardiac Surgery, Coronary Artery Bypass Grafting, Valve Surgery, Kidney Injury
- Trial name
- NCT00628264
- Testing
- AP214
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Action Pharma A/S
Microcirculation, Anesthetic Complication Spinal
Effect of Anesthetics on Microcirculation in Patients Undergoing Off-pump Coronary Artery Bypass Surgery
Volatile anesthetics, such as sevoflurane and desflurane, are commonly used in patients undergoing cardiac surgeries including off-pump coronary artery bypass.
- Trial name
- NCT03209193
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Bypass
Registry for Quality Assessment With Ultrasound Imaging and TTFM in Cardiac Bypass Surgery
The purpose of the registry is to collect information regarding the number and type of coronary artery bypass (CAB) surgical procedure changes that are made based on intraoperative guidance information using transit time flow…
- Trial name
- REQUEST (NCT02385344)
- Testing
- Medistim device
- Where
- 7 sites in United States, Canada and 4 more
- Volunteers
- 1,046 people
- Sponsor
- Medistim ASA
Surgical Site Infection, Coronary Artery Bypass Grafting (CABG)
Effect of Nurse-Led Education and Tele-Interventions on Reducing Surgical Site Infections in Patients After Coronary Artery Bypass Surgery: a Clinical Trial
The goal of this clinical trial is to determine if nurse-led education and tele-interventions can reduce the incidence of surgical wound infections in patients after coronary artery bypass surgery.
- Trial name
- NCT06586749
- Testing
- Group B: nurse-led education, Group C: nurse-led education and implementation of teleinterventions
- Where
- Greece
- Volunteers
- 220 people
- Sponsor
- Hellenic Mediterranean University
Coronary Artery Bypass, Off-Pump
Prospective Cohort Study on Minimal Invasive Coronary Surgery
CABG technology is recognized as the preferred treatment, and its major adverse cardiac and cerebral event(MACCE) incidence and mortality are lower than percutaneous coronary intervention(PCI).
- Trial name
- PCSMICS (NCT04267835)
- Testing
- MIDCAB, thoracotomy OPCABG
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University Third Hospital
Coronary Bypass Graft Stenosis, Valvular Heart Disease
Comparison of Post-operation Cardiopulmonary Capacity of Patients Underwent Conventional and Robot-assisted Coronary Artery Bypass Graft and Valve Replacement Surgery
Robotic surgery is one of the most popular minimally invasive procedures for patients with coronary artery disease or valvular diseases.
- Trial name
- NCT05430568
- Testing
- robot-assisted surgery
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taichung Veterans General Hospital
Coronary Artery Bypass Graft (CABG), Chest Tubes
Chest Tube-Delivered Bupivacaine to Decrease Postoperative Pain After Cardiac Surgery
Background: After heart surgery, patients require temporary chest tubes - plastic drains placed inside the chest to prevent fluid building up around the heart and lungs.
- Conditions
- Coronary Artery Bypass Graft (CABG), Chest Tubes, Post Operative Pain Control
- Trial name
- FREEZE-B (NCT07643506)
- Testing
- 0.5% Bupivacaine without epinephrine, 10cc injection of normal saline (0.9%)
- Volunteers
- 60 people
- Sponsor
- University of Calgary
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