Clinical trials: Coronary Artery Bypass Surgery
Cardiac Surgery, Coronary Artery Bypass Grafting
Desflurane vs. Propofol for Cardiac Anesthesia
To investigate whether the inhaled anesthetic desflurane, compared with propofol, exerts cardioprotective effects and reduces the incidence of severe postoperative major cardiac events in patients undergoing coronary artery…
- Trial name
- DECIDE-CABG (NCT07116733)
- Testing
- Desflurane group, Propofol group
- Where
- 14 sites in China
- Volunteers
- 3,560 people
- Sponsor
- Xijing Hospital
Biomarkers, Coronary Artery Bypass Surgery
Dynamics of microRNA Expression and Systemic Inflammatory Response in POCD After Cardiac Surgery
Postoperative cognitive decline (POCD) is one of the most common complications after cardiac surgery. It is characterized by impaired memory, attention, and executive functions and can have long-term consequences.
- Conditions
- Biomarkers, Coronary Artery Bypass Surgery, Interleukin-6, MicroRNAs
- Trial name
- NCT07231731
- Where
- Croatia
- Volunteers
- 48 people
- Sponsor
- Osijek University Hospital
Coronary Artery Bypass Graft Surgery (CABG), Radial Artery Grafts
Effect of Oral Isosorbide Mononitrate Plus Amlodipine Antispasm Therapy on Outcomes of Radial Artery Grafts After CABG
The goal of this clinical trial is to to evaluate the effect of oral isosorbide mononitrate plus amlodipine antispasm therapy on outcomes of radial artery grafts in patients underwent primary isolated CABG.
- Conditions
- Coronary Artery Bypass Graft Surgery (CABG), Radial Artery Grafts, Graft Failure
- Trial name
- ASRAB (NCT06730945)
- Testing
- Oral isosorbide mononitrate 4+ amlodipine
- Where
- China
- Sponsor
- Ruijin Hospital
Coronary Artery Bypass, Off-Pump, Minimally Invasive Cardiac Surgery
MInithoraCotomy vs Sternotomy for Multivessel Coronary Artery Bypass Grafting: A Partially Randomized Patient Preference Trial Assessing Quality of Life and Patency Outcomes
This trial will address essential questions of the efficacy and safety of MICS-CABG in addition to the quality of life and patency rate of the grafts.
- Trial name
- NCT04795193
- Testing
- Minimal invasive coronary surgery, Off-pump coronary artery bypass surgery
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Peking University Third Hospital
Coronary Artery Bypass Grafting, Off-pump Coronary Artery Bypass
Safety and Effectiveness of No-touch Technique for Ascending Aorta in MICS-CABG
The goal of this single-center prospective cohort study is to compare perioperative safety metrics and follow-up survival analyses in patients receiving Minimally Invasive Cardiac Surgery Coronary Artery Bypass…
- Conditions
- Coronary Artery Bypass Grafting, Off-pump Coronary Artery Bypass, Minimally Invasive Cardiac Surgery, Coronary Arterial Disease (CAD)
- Trial name
- NCT07172620
- Testing
- Non-extracorporeal multiple coronary artery bypass graft (CABG) performed under direct visualization through a small incision in the left side of the chest., Multi-branch coronary artery bypass grafting with conventional median open heart and off-pump circulation
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Peking University Third Hospital
Coronary Artery Bypass Graft Surgery, Atherosclerosis
Effect of Evolocumab on Saphenous Vein Graft Patency Following Coronary Artery Bypass Surgery
The purpose of this study is to determine if evolocumab added to regular statin therapy improves vein graft patency after coronary artery bypass graft (CABG) surgery.
- Conditions
- Coronary Artery Bypass Graft Surgery, Atherosclerosis, Vein Occlusion
- Trial name
- NEWTON-CABG (NCT03900026)
- Testing
- Evolocumab
- Where
- 22 sites in United States, Australia and 2 more
- Volunteers
- 782 people
- Sponsor
- Unity Health Toronto
Coronary Artery Bypass Graft Surgery, Coronary Artery Disease
Cardiac Rehabilitation in Coronary Artery Bypass Graft Surgery
This randomized controlled trial investigates the comparative effects of a combined preoperative and postoperative cardiac rehabilitation program versus a postoperative-only program on functional capacity, pulmonary function…
- Trial name
- NCT07006441
- Testing
- Preoperative Cardiac Rehabilitation, Postoperative Cardiac Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Atlas University
Pain, Anxiety
Progressive Relaxation Exercises Before Mobilization:Effects on Pain, Anxiety and Physiologic Parameters CABG Patients
This study is planned as a randomized controlled experimental study to determine the effect of progressive relaxation exercises applied before mobilization on pain, anxiety and physiological parameters in patients undergoing…
- Conditions
- Pain, Anxiety, Physiological Parameter, Mobilization
- Trial name
- NCT06726239
- Testing
- Progressive relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Istanbul University - Cerrahpasa
CABG-patients, Saphenectomy
Clinical Impact of Surgical Wound Morbidity According to the Type of Saphenous Vein Harvesting Technique (Endoscopic vs. Open) in Patients Undergoing Myocardial Revascularization Surgery
The goal of this clinical trial is to compare two different techniques: endoscopic saphenous vein harvesting versus conventional open harvesting in patients undergoing coronary artery bypass grafting, either alone or in…
- Conditions
- CABG-patients, Saphenectomy, Endoscopic Surgery, Wound Complications
- Trial name
- EndOSiC (NCT07002658)
- Testing
- Harvesting of the saphenous vein graft
- Where
- Spain
- Volunteers
- 356 people
- Sponsor
- Hospital San Carlos, Madrid
Coronary Artery Bypass Grafting (CABG) Surgery
A Study Testing the Elana Device for Multi-Artery Heart Bypass Surgery
The purpose of the trial is to evaluate the feasibility and safety of multiple Elana Anastomotic Systems to anastomose multiple arterial grafts during coronary artery bypass grafting (CABG).
- Trial name
- MULTI-CAB (NCT07005843)
- Testing
- The Elana Anastomotic System
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- AMT Medical BV
Coronary Artery Bypass Surgery, Cognitive Impairment
Evaluation of the Safety and Efficacy of Ang-(1-7) to Enhance Cognitive Function in Participants Undergoing CABG
Coronary Artery Bypass Graft (CABG) is a surgical procedure known to be associated with cognitive impairment. Mechanisms of cognitive impairment are complex but may include insufficient oxygenation and inflammation due to…
- Trial name
- NCT03252093
- Testing
- Angiotensin-(1-7)
- Where
- 5 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Arizona
Cardiac Rehabilitation, Coronary Artery Bypass Surgery
Cardiac Rehabilitation After Coronary Artery Bypass Graft Surgery
This study aimed to evaluate the effects of cardiac rehabilitation program after CABG surgery on quality of life, sleep quality, anxiety, depression and cardiopulmonary functions.
- Trial name
- NCT06970938
- Testing
- Cardiac rehabilitation program
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Muhammed Onur Hanedan
Patient Care Team, Coronary Artery Disease
Developing an Intervention to Improve the Non-Technical Skills of the Cardiac Surgical Teams
Teams of several medical professionals conduct high-risk cardiac surgical procedures. These professionals work in complex, stressful operating room environments requiring effective communication and teamwork skills.
- Conditions
- Patient Care Team, Coronary Artery Disease, Coronary Artery Bypass, Surgery
- Trial name
- NCT06257511
- Testing
- Simulation-Based Mastery Learning of the Non-technical skills
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Coronary Artery Bypass Surgery, Paravertebral Block
The Effect of Paravertebral Block on Recovery After CABG Surgery
The study aims to evaluate the analgesic efficacy of paravertebral block, mobilization speed, respiratory functions, and complication rates in patients who have undergone cardiac surgery and are monitored in the intensive care…
- Trial name
- NCT06882083
- Testing
- paravertebral block
- Volunteers
- 120 people
- Sponsor
- Adiyaman University Research Hospital
Coronary Artery Bypass Graft Surgery (CABG)
Association Between μFR And CABG Outcomes
The goal of this observational study is to evaluate the association between Murray law-based quantitative flow reserve and outcomes after coronary artery bypass graft surgery.
- Trial name
- NCT06844721
- Where
- South Korea
- Volunteers
- 945 people
- Sponsor
- Seoul National University Hospital
Coronary Arterial Disease (CAD), Fraility
Correlation of Euroscore-II, STS Risk Scoring Systems and Frailty Tests with Cardiac Histopathological Findings in Coronary Bypass Surgery
Various risk classification systems are used to predict postoperative mortality and morbidity development in cardiac surgery. Risk calculation with these systems is a guide in determining preoperative strategies, performing cost…
- Conditions
- Coronary Arterial Disease (CAD), Fraility, Histopathology, Cardiac Risk Factors
- Trial name
- NCT06784609
- Testing
- Coronary Artery Bypass Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Coronary Artery Bypass Graft Surgery (CABG), Pain
Effect of Swedish Hand Massage on Pain in Patients Undergoing CABG Surgery
Coronary Artery Bypass Grafting (CABG) surgery is performed commonly today. Heart surgery performed on more than two million individuals every year leads patients experience severe postoperative pain for causes such as cutting of…
- Conditions
- Coronary Artery Bypass Graft Surgery (CABG), Pain, Pain Management, Nursing
- Trial name
- NCT06688617
- Testing
- Swedish Hand Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University - Cerrahpasa
Post Coronary Artery Bypass Grafting, Post-Cardiac Surgery Patients
Effect of Respiratory Trainer on Cardiopulmonary Functions in Patients with Upper Cross Syndrome Post-Cardiac Surgery
The purpose of this study is to investigate if there is any effect of the respiratory training on cardiopulmonary functions in patients with upper cross syndrome post-cardiac surgery.
- Conditions
- Post Coronary Artery Bypass Grafting, Post-Cardiac Surgery Patients, Upper Cross Syndrome, Respiratory Muscle Weakness
- Trial name
- NCT06673953
- Testing
- Respiratory Muscle Training by (The Breather), Traditional physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Patients Waiting for Coronary Artery Bypass Graft Surgery, Patients Waiting for Aortic Valve Repair or Replacement
Pre-operative Rehabilitation for Reduction of Hospitalization After Coronary Bypass and Valvular Surgery.
The PREHAB study is a clinical trial where frail patients waiting for heart surgery are randomly chosen to either receive the current standard of care or to participate in an 8-week exercise/education program at a community-based…
- Conditions
- Patients Waiting for Coronary Artery Bypass Graft Surgery, Patients Waiting for Aortic Valve Repair or Replacement, Patients Waiting for Mitral Valve Repair or Replacement, Patients Waiting for Combined Procedures. (CAGB and Valve)
- Trial name
- PREHAB (NCT02219815)
- Testing
- Prehab Intervention
- Where
- 5 sites in Canada
- Volunteers
- 89 people
- Sponsor
- St. Boniface Hospital
Coronary Artery Bypass Graft Surgery, Aortic Valve Replacement
Outcomes After Albumin Vs Lactated Ringer's Solution in CABG and AVR Procedures
This is a prospective, randomized, double-blinded study to compare the use of albumin versus lactated Ringer's solution in patients undergoing coronary artery bypass graft surgery and in patients undergoing aortic valve…
- Trial name
- NCT04652375
- Testing
- Albumin Solution, Lactated Ringer's Solution
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- Yale University