Clinical trials: Coronary Artery Bypass Surgery
Coronary Artery Bypass, Coronary Artery Bypass Graft
A Single Centre Study Comparing Continuous Interstitial Fluid Lactate Detection to Standard Measurements of Lactate in Patients Undergoing Elective Coronary Artery Bypass Graft Surgery and/or Valve Replacement.
The main goal of this study is to see if a wearable device can reliably track changes in lactate levels in the body. We\'ll compare the device\'s readings to standard blood tests to ensure accuracy.
- Conditions
- Coronary Artery Bypass, Coronary Artery Bypass Graft, Coronary Artery Bypass Graft Surgery (CABG), Valve Replacement
- Trial name
- CONTINUUM LINT (NCT06602336)
- Testing
- Continuous Lactate Monitoring Device
- Where
- United Kingdom
- Volunteers
- 61 people
- Sponsor
- Queen Mary University of London
Chest Wall Blocks
Serratus Anterior Plan Block (SAP) and Pectoralis (PECSI-II) Blocks on Left Internal Mammarian Artery (LIMA) Blood Flow
To investigate whether the anterior chest wall blocks performed before the surgery have an effect on the LIMA (left internal mammarian artery) blood flow in patients who will undergo coronary artery bypass surgery.
- Trial name
- NCT05907798
- Testing
- LIMA Blood flow
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Coronary Artery Disease, Ischemic Heart Disease
Coronary Revascularization Outcomes Within Necessary Sex and Gender Aspects
The aim of this observational single-centre study is the optimization of coronary artery bypass grafting (CABG) tactics considering gender and sex approach on the basis of complex comparative evaluation of surgical…
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Coronary Artery Bypass Grafting
- Trial name
- CROWN-SAGA (NCT06749171)
- Testing
- coronary artery bypass grafting
- Where
- Russia
- Volunteers
- 400 people
- Sponsor
- Federal State Budgetary Institution "Federal Center for Cardiovascular Surgery named after S.G. Sukh
Coronary Artery Bypass Surgery
CD0104 VEST II Post Marketing Surveillance Study
This study is designed to collect post market data on use of the VEST, particularly on saphenous vein grafts to the right territory of the heart.
- Trial name
- VEST II (NCT02332330)
- Testing
- VEST
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 30 people
- Sponsor
- Vascular Graft Solutions Ltd.
Coronary Artery Disease
Association Between Vitamin D and Perioperative Hemoglobin Levels in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery: Role of Hepcidin
Preoperative anemia is present in more than 50% of patients undergoing cardiac surgery, which is associated with increased risk of transfusion, increased length of stay in the intensive care unit, and increased incidence of renal…
- Trial name
- NCT04986033
- Where
- South Korea
- Volunteers
- 135 people
- Sponsor
- Yonsei University
Analgesic Effects, Systemic Stress Response
Bilateral Ultrasound Guided Pectoralis Nerve Block Induces Hemodynamic Stability With Reducing Systemic Stress Response for Off-pump Coronary Artery Bypass Graft
Opioids used in attenuation of the neuroendocrine stress response in patients undergoing off-pump coronary artery bypass graft (OPCAB) it produces predictable satisfactory analgesia and sedation but with side effects such as…
- Conditions
- Analgesic Effects, Systemic Stress Response, Hemodynamic Stability
- Trial name
- NCT03734848
- Testing
- Bilateral Ultrasound Guided Pectoralis Nerve Block.
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cardiovascular Disease, Coronary Artery Disease
Italian Registry on Unprotected Left Main
The RITMO (Registro Italiano sul trattamento del Tronco coMune non protettO) observational study will appraise the prevalence, management strategy, and prognosis of unprotected left main coronary artery disease in Italy.
- Trial name
- RITMO (NCT00612053)
- Where
- Italy
- Volunteers
- 1,200 people
- Sponsor
- University of Turin, Italy
Coronary Artery Bypass Grafting
Risk Factors for Deep Sternal Wound Infection After Coronary Artery Bypass Grafting
Deep sternal wound infection (DSWI) constitutes a serious complication after coronary artery bypass grafting (CABG) surgery with potentially devastating consequences for patients.
- Trial name
- NCT07043296
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hypoxemia, Recruitment
Comparison of Four Different Recruitment Maneuvers in Patients After Coronary Surgery
The risk of respiratory failure after cardiac surgery is high, and it may result in many complications. The maneuver of alveolar recruitment may improve the oxygen transport in the human organism.
- Trial name
- RECR-CABG (NCT01457651)
- Testing
- Alveolar recruitment
- Where
- Russia
- Volunteers
- 76 people
- Sponsor
- Northern State Medical University
Myocardial Reperfusion Injury
The Role of Pioglitazone in Vascular Transcriptional Remodeling
Acute myocardial infarction (AMI) remains the leading cause of death worldwide. In this scenario, early coronary reperfusion is the main therapeutic strategy as it substantially reduces mortality.
- Trial name
- PREVALENT (NCT05775380)
- Testing
- Pioglitazone 45 mg
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Campinas, Brazil
Coronary Artery Bypass Graft Surgery, Coronary Artery Disease
Cardiac Rehabilitation in Coronary Artery Bypass Graft Surgery
This randomized controlled trial investigates the comparative effects of a combined preoperative and postoperative cardiac rehabilitation program versus a postoperative-only program on functional capacity, pulmonary function…
- Trial name
- NCT07006441
- Testing
- Preoperative Cardiac Rehabilitation, Postoperative Cardiac Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Atlas University
Enhanced Recovery After Cardiac Surgery
Pecto-intercostal Plane Block in On-pump Coronary Bypass Graft Surgery
Fast track and ultrafast track cardiac anaesthesia appear to demonstrate improved outcomes without compromising patient safety. Their benefits include shorter intensive care unit stays, reduced duration of mechanical ventilation…
- Trial name
- NCT04343105
- Testing
- pecto-intercostal plane block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Coronary Artery Disease
Secondary Prevention After Coronary Bypass Surgery
Despite immediate symptomatic success after coronary bypass surgery in patients with coronary artery disease, this effect is not sustained over time since risk factors for coronary artery disease are still in place.
- Trial name
- NCT00843089
- Testing
- Education
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Jeffrey Kramer, MD
Coronary Artery Disease With Need for Bypass Surgery, Coronary Artery Disease(CAD)
Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery
This interventional prospective randomized study is designed to compare hemodynamic management using postural mobilization (+/- noradrenaline) versus noradrenaline only in patients undergoing open-heart coronary artery bypass…
- Conditions
- Coronary Artery Disease With Need for Bypass Surgery, Coronary Artery Disease(CAD), Coronary Artery Bypass, Off Pump Coronary Artery Bypass Graft
- Trial name
- OPTICAB (NCT07163858)
- Testing
- passive leg raising for hemodynamic management during open-heart coronary bypass grafting, Use of Noradrenaline only in control group
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Infirmerie Protestante de Lyon
Coronary Artery Disease, Coronary Artery Bypass Grafting
Total Arterial Revascularization (TAR)
Total arterial revascularisation with in-situ confihuration of BITA is superior than y-graft in patients underwent CABG.
- Trial name
- NCT03753048
- Testing
- Y-Graft, In-Situ
- Where
- Russia
- Volunteers
- 880 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Intubation;Difficult, Coronary Bypass
Comparison of Two Different Videolaryngoscopes Regarding Hemodynamic Parameters in Open Heart Surgey
Endotracheal intubation increased the heart rate and blood pressure in normal patients. Open heart surgery patients are more prone to hemodynamic variability.
- Trial name
- NCT03483285
- Testing
- airtraq, storz
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kocaeli University
Anesthesia, Hypothermia
Examine the Effects of Maintaining Body Core Temperature During CABGs
Although data on cardioprotective effects (as profile of troponin I)of perioperative maintenance of normothermia during CABGs are already known, little is known about the effects of maintaining normothermia on clinical outcomes…
- Conditions
- Anesthesia, Hypothermia, Coronary Artery Bypass Grafting
- Trial name
- NCT00791050
- Testing
- Allon Thermowrap. MTRE Advanced Technologies Ltd.
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Centro Cardiologico Monzino
Coronary Artery Disease
PeRcutaneous cOronary Intervention of Native Coronary arTery Versus Venous Bypass Graft in Patients With Prior CABG
Multi-centre, randomised clinical trial with anticipated 17 European centres: in the Netherlands, Belgium, Germany and UK. Patients with a dysfunctional bypass graft with a clinical indication for revascularization will be…
- Trial name
- PROCTOR (NCT03805048)
- Testing
- Percutaneous coronary intervention
- Where
- 21 sites in Belgium, Germany and 3 more
- Volunteers
- 221 people
- Sponsor
- Amsterdam UMC, location VUmc
Cardiac Event, Arrest; Cardiac, Complicating Surgery
Prevena Incision Management
The question this research project wants to explore is whether using the Prevena Incision Management System (Prevena) will improve sternal wound edge oxygenation in patients undergoing Coronary Artery bypass surgery with…
- Conditions
- Cardiac Event, Arrest; Cardiac, Complicating Surgery, Coronary Bypass Graft Stenosis, Complication of Coronary Artery Bypass Graft
- Trial name
- Prevena (NCT02814084)
- Testing
- Bilateral Internal Mammary Artery grafts, Prevena
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Coronary Artery Disease
The Stent or Surgery (SoS) Trial
This study compared two different methods of restoring blood flow to the heart when there has been a narrowing or blockage in the blood vessels that supply the heart.
- Trial name
- NCT00475449
- Testing
- percutaneous coronary intervention, coronary artery bypass grafting
- Volunteers
- 988 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
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