Clinical trials: Coronary Artery Bypass Surgery
AF - Atrial Fibrillation
Predictors of Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting: A Prospective Cohort Study
There are a wide range of significant epidemiological, clinical, and operative predictors for the development of post-CABG AF including older age, female gender, large LA diameter, higher CHA2DS2-VASc score, valve replacement and…
- Trial name
- NCT04193813
- Testing
- Observational
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Ain Shams University
Complication of Coronary Artery Bypass Graft, Complication of Extracorporeal Circulation
Combined Use of a Novel Cardioplegic Formula With MPS ® Using the MiECC in Isolated CABG Versus OPCABG
A patient group receiving a novel cardioplegic formula with MPS ® (Myocardial protection system) and using the MiECC (Minimal extracorporeal circulation system) when undergoing coronary artery bypass grafting is compared to a…
- Trial name
- OPCBAG (NCT03609723)
- Testing
- CABG
- Where
- Switzerland
- Volunteers
- 2,433 people
- Sponsor
- University Hospital, Basel, Switzerland
D017202
ADR-002K for Patients With Ischemic Cardiomyopathy Who Undergo Coronary Artery Bypass Surgery
Ischemic cardiomyopathy undergoing coronary artery bypass surgery
- Trial name
- NCT04695522
- Testing
- ADR-002K administration
- Where
- Japan
- Volunteers
- 6 people
- Sponsor
- Osaka University
Coronary Artery Disease
Topical Application of Tranexamic Acid to Reduce Post-operative Bleeding in Coronary Artery Bypass Surgery
The goal of this project is to determine whether the use of tranexamic acid, a clot-promoting drug, applied topically over the heart in coronary artery bypass graft surgery (CABG) will reduce post operative blood loss.
- Trial name
- NCT01519245
- Testing
- Tranexamic Acid, normal saline
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Coronary Artery Bypass Surgery
Exercise Tolerance in Patients With CABG and Sternotomy vs. Patients With Minimally Invasive Coronary Surgery
In this study, up to 20 healthy individuals, 20 endo-ACAB patients, and 20 CABG patients undergo a maximal cardiopulmonary exercise test after hospital discharge (for patients only). Exercise tolerance is compared between groups.
- Trial name
- ENDO-ACAB (NCT02433951)
- Testing
- Cardiopulmonary exercise test
- Where
- Belgium
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Coronary Artery Disease, Obesity
Structured Physiotherapy Program in Obese and Non-obese Patients
A routine physiotherapy program has been shown to be effective in the prevention and treatment of cardiopulmonary diseases. It also significantly increases functional capacity following coronary artery bypass grafting.
- Trial name
- NCT05357937
- Testing
- standard physiotherapy program
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- University of Jazan
Post Operative Cognitive Dysfunction
Pre-operative Intra-nasal Dexmedetomidine or Insulin for Prevention of Early Post-operative Cognitive Dysfunction in Patients Undergoing Elective Coronary Artery Bypass Graft.
On pump coronary revascularization is a very common leading cause for post-operative cognitive dysfunction regarding patient age grouping and diffuse systemic inflammatory response induced by bypass machine .
- Trial name
- NCT06741566
- Testing
- intranasal saline group, intranasal insulin, Intranasal dexmedetomidine
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
Effect of Drug in CABAG Patients
Effect of Dexmedetomidine on Left Ventricular Function in Coronary Artery Bypass Graft Surgery Outcome
50 patients of both sexes undergoing elective CABG surgery will be randomly divided into 2 groups, study group (Dex) group and control group (C) to determine the effect of dexmedetomidine on the peri-operative hemodynamic changes…
- Trial name
- CABAG (NCT05778305)
- Testing
- Dexmedetomidine, normal saline
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Surgical Site Infection (SSI), Mediastinitis
Use of Platelet-Rich Plasma to Reduce Sternal Wound Complications After CABG With Median Sternotomy
The goal of this clinical trial is to learn whether applying autologous platelet-rich plasma (PRP) to the sternal wound during heart surgery improves wound healing and reduces complications after surgery.
- Conditions
- Surgical Site Infection (SSI), Mediastinitis, Delayed Wound Healing
- Trial name
- NCT07352020
- Testing
- Autologous Platelet-Rich Plasma (PRP) Application, Standard Sternal Wound Closure
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Coronary Artery Disease
PCI vs. CABG in the Treatment of Unprotected Left Main Stenosis
Coronary Artery Bypass Grafting Versus Drug Eluting Stent Percutaneous Coronary Angioplasty in the Treatment of Unprotected Left Main Stenosis.
- Trial name
- LeftMain/NOBLE (NCT01496651)
- Testing
- Percutaneous coronary intervention, Coronary artery bypass graft operation
- Where
- Denmark
- Volunteers
- 1,201 people
- Sponsor
- Evald Hoej Christiansen
Post Operative Pain, Post Operative Anxiety
The Effect of Virtual Reality on Postoperative Pain and Anxiety in Cardiac Surgery.
The objective of this study is to investigate the effect of VR on post-operative pain and anxiety management in cardiac surgery patients undergoing a coronary artery bypass grafting (CABG) procedure.
- Conditions
- Post Operative Pain, Post Operative Anxiety, Heart Surgery, Coronary Artery Bypass Grafting
- Trial name
- VRECOVERY (NCT06001502)
- Testing
- Virtual Reality distraction therapy
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Cardiac Revascularization
ICU Stay in Patients With Low Ejection Fraction Undergoing Cardiac Revascularization: Comparison of On-pump vs Off-pump Coronary Artery Bypass Grafting
Coronary artery bypass graft (CABG) surgery can result in severe postoperative complications, such as renal and pulmonary failure.
- Trial name
- NCT04639856
- Testing
- Coronary Artery Bypass Grafting
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Armed Forces Institute of Cardiology, Pakistan
Coronary Artery Bypass Surgery, Cardiopulmonary Bypass
Safety and Effectiveness of the Medtronic Resting Heart Bypass System in Heart Surgery Patients
The purpose of this study is to determine if the Medtronic Resting Heart Bypass system is safer and results in less inflammatory reaction than traditional bypass machines used in coronary artery bypass surgery.
- Trial name
- NCT00303641
- Testing
- Medtronic Resting Heart Bypass System
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Muscle Wasting
Effects of Functional Electrical Stimulation in Patients Undergoing Coronary Artery Bypass Grafting Surgery
Even with major advances in clinical therapy and percutaneous interventions, coronary artery bypass grafting (CABG) is the most common cardiac surgery performed worldwide and is an effective treatment in reducing symptoms and…
- Trial name
- NCT03560713
- Testing
- Functional Electrical Stimulation (FES)
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Universidade Federal de Santa Maria
Myocardial Edema
Effect of 80-mg Atorvastatin on Myocardial Edema
The purpose of this study is to determine whether atorvastatin 80mg can reduce the development of myocardial edema following coronary artery bypass surgery. This study also want to determine: 1.
- Trial name
- NCT02901379
- Testing
- Atorvastatin 80mg, Atorvastatin 10mg
- Volunteers
- 40 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Coronary Heart Disease, Artificial Intelligence
Effects of AI Assisted Follow-up Strategy on Secondary Prevention in CABG Patients
The present study is trying to find out whether artificial intelligence assisted follow-up strategy will improve secondary prevention in CABG patients.
- Conditions
- Coronary Heart Disease, Artificial Intelligence, Sleep Apnea
- Trial name
- NCT04636996
- Testing
- artificial intelligence assisted follow-up
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Coronary Artery Bypass Graft Surgery Patients
Music Therapy and Mindfulness Meditation
Coronary artery bypass graft surgery (CABG) involves bypassing a blocked artery with a healthy blood vessel elsewhere from body allowing the blood flow to be restored to heart.
- Trial name
- NCT06631846
- Testing
- Music therapy, Mindfulness meditation, Music therapy and mindfulness meditation
- Sponsor
- Universiti Tunku Abdul Rahman
Pregabalin, Delirium Treatment
Pregabalin Versus Dexmedetomidine for Delirium Treatment After Coronary Artery Bypass Grafting
The aim of this study is to determine the effect of pregabalin versus dexmedetomidine on the treatment and lasting duration of delirium in fast tracking elderly patients after Coronary Artery Bypass Grafting.
- Conditions
- Pregabalin, Delirium Treatment, Coronary Artery Bypass Grafting, Dexmedetomidine
- Trial name
- NCT05640453
- Testing
- Pregabalin, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Coronary Artery Disease
Effect of Intravenous Ferric Carboxymaltose on Hemoglobin Response and Transfusion in Patients With Iron Deficiency Anemia After Off-Pump Coronary Artery Bypass Grafting
In this prospective open-label randomized tral, 100 patients with elective off-pump coronary artery bypass (OPCAB) or minimal invasive direct coronary bypass (MIDCAB) surgery were enrolled.
- Trial name
- NCT04898569
- Testing
- Ferinject, Normal Saline Flush
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Wounds and Injuries, Wound Infection
Effects of Early Postoperative Showering After Coronary Artery Bypass Grafting Using Bilateral Internal Thoracic Artery
The study to evaluate effects of early postoperative showering after coronary artery bypass grafting using bilateral internal thoracic artery
- Trial name
- NCT06237283
- Testing
- Early shower
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Sejong General Hospital
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