Clinical trials: Coronary Artery Disease (CAD)
Coronary Artery Disease
Registry Experience at the Washington Hospital Center, DES - Endeavor for Myocardial Infarction
Single-center registry of patients treated with at least one Endeavor, zotarolimus-eluting, Stent as the primary treatment for acute coronary syndrome at the Washington Hospital Center, with the aim of assessing clinical success…
- Trial name
- REWARDS-EMI (NCT01003717)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Rebecca Torguson
Myocardial Infarction
Prevalence and Long-term Impact of Non-atherosclerotic CAD
Despite a relatively high prevalence of non-atherosclerotic coronary artery disease (NACAD) among young women, the majority of these abnormalities were misdiagnosed in this population, and thus treatments were not targeted…
- Trial name
- PRYME (NCT01479140)
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Cardiology Research UBC
Heart Failure, Coronary Artery Disease
The Usefulness of Growth Differentiation Factor 15 (GDF-15) for Risk Stratification in Cardiac Surgery
Growth determination factor 15 (GDF-15) and high sensitive troponin-t (hsTnT) are emerging humoral markers for risk stratification in clinically stable heart failure patients and in patients with stable coronary artery disease.
- Trial name
- NCT01166360
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- University of Luebeck
Non-Obstructive Coronary Atherosclerosis
PericOronary INflammaTion in Non-Obstructive Coronary Artery Disease
Among patients with ischemic heart disease who are referred for coronary angiography, a substantial proportion have non-obstructive coronary artery disease (CAD).
- Trial name
- POINT-NOCAD (NCT05031520)
- Testing
- Coronary computed tomography angiography (CCTA), Isovue, Nitroglycerin
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- NYU Langone Health
Coronary Artery Disease, Acute Coronary Syndrome
PRESSUREwire Study
The purpose of this study is to understand routine use of FFR (Fractional Flow Reserve) and alternate indices in clinical practice.
- Trial name
- NCT02935088
- Testing
- Fractional Flow Reserve
- Where
- 71 sites in United States, Austria and 13 more
- Volunteers
- 2,217 people
- Sponsor
- Abbott Medical Devices
Gout, Coronary Artery Disease
Uric Acid Study in Healthy Male Volunteers
This study is being conducted to examine the effect of AZD6140 on the levels of certain chemicals in subjects' blood and urine.
- Trial name
- NCT00738842
- Testing
- AZD6140
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Cardiovascular Diseases, Coronary Disease
Training Levels Comparison Trial
To determine the effects of high or low intensity long-term exercise conditioning in patients with coronary artery disease.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00000460
- Testing
- Low intensity exercise, High intensity exercise
- Sponsor
- University of Alabama at Birmingham
Sleep Apnea, Diabetic Nephropathy Type 2
Sleep Apnea, Coronary Atherosclerosis and Heart Failure in Diabetes Patients With Nephropathy
Background: Diabetes, and especially diabetic kidney disease is associated with the development of cardiovascular disease such as calcification in the coronary arteries and heart failure.
- Conditions
- Sleep Apnea, Diabetic Nephropathy Type 2, Coronary Atheroscleroses, Heart Insufficiency
- Trial name
- SLEEP (NCT04549324)
- Where
- Denmark
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Coronary Artery Disease
Assessing Diagnostic Value of Non-invasive FFRCT in Coronary Care
The objective of the HeartFlow ADVANCE Registry is to evaluate utility, clinical outcomes and resource utilization of FFRCT-guided evaluation in clinically stable, symptomatic patients with coronary artery disease (CAD) in order…
- Trial name
- ADVANCE (NCT02499679)
- Volunteers
- 4,737 people
- Sponsor
- HeartFlow, Inc.
Coronary Heart Disease
Efficacy and Safety of Aspirin Therapy With CABG
evaluate the safety of preoperative aspirin therapy when performing bypass surgery in conditions of artificial blood circulation
- Trial name
- NCT02942680
- Testing
- acetylsalicylic acid started for 24 hours before surgery, acetylsalicylic acid stayed for 5 days before surgery
- Where
- Russia
- Volunteers
- 350 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Artery Disease, HMG-CoA Reductase Inhibitor Toxicity
Pleiotropic Effects of Atorvastatin in High Cardiovascular Risk Patients
The present study constitutes a study examining the effect of atorvastatin on vascular function in high cardiovascular risk patients.
- Conditions
- Coronary Artery Disease, HMG-CoA Reductase Inhibitor Toxicity, Atherosclerosis, Oxidative Stress
- Trial name
- NCT01013103
- Testing
- Atorvastatin, high vs low dose
- Where
- Greece
- Volunteers
- 72 people
- Sponsor
- Hippocration General Hospital
Coronary Disease
Pro-calcitonin Marker as Indicator of Ischemia in Patients With Complicated Coronary Intervention.
The aim of this study is to determine on preliminary basis weather an elevated pro-calcitonin level can be used to assess ischemia as a result of coronary artery complications during percutaneous coronary intervention (PCI).
- Trial name
- NCT01609569
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Saint Michael's Medical Center
Coronary Artery Disease, Drug Eluting Stent
CREATE Trial, Prospective, Observational Study
Observation of the safety and effectiveness of Cre8 stent, Cre8 evo stent in patients with ischemic heart disease with long coronary lesions
- Trial name
- NCT05658250
- Testing
- CRE8 polymer-free Amphilimus-eluting stent, Cre8 evo stent
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Coronary Artery Disease, Hyponatremia
Hyponatremia and Hypoalbuminemia is Morbimortality Predictors in Coronary Artery Bypass Graft Surgery
Coronary artery disease is a common medical disease in many populations. The pathogenesis of this disease is very complex. Surgery is one of the treatment choices. Assessing the risk factors will improve the surgical outcome.
- Conditions
- Coronary Artery Disease, Hyponatremia, Hypoalbuminemia
- Trial name
- NCT02765061
- Volunteers
- 1,157 people
- Sponsor
- Ankara University
Coronary Artery Disease
Effect of FFRCT-angio in Functional Diagnosis of Coronary Artery Stenosis
Coronary CT angiography (CTA) or invasive coronary angiography (CAG) is usually performed to evaluate the severity of coronary stenosis depending on the probability of CAD.
- Trial name
- NCT04493086
- Testing
- FFRCT-angio
- Where
- China
- Volunteers
- 500 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Atherosclerotic Cardiovascular Disease (ASCVD), Coronary Heart Disease (CHD)
VICTORION-ASCERTAIN: Implementation Study (v-ASCERTAIN)
The goal of this study is to understand and compare an alternative model of care in comparison to the usual model of care in include male and female participants ≥18 years of age with a history of ASCVD (hear and blood vessels…
- Conditions
- Atherosclerotic Cardiovascular Disease (ASCVD), Coronary Heart Disease (CHD), Cerebrovascular Disease, Peripheral Arterial Disease (PAD)
- Trial name
- v-ASCERTAIN (NCT05834673)
- Testing
- SMS messages, Telephone-based support calls, GP Education
- Where
- Australia
- Volunteers
- 6 people
- Sponsor
- Monash University
Cardiovascular Diseases, Heart Diseases
Cardiovascular Disease Mortality in The NAS-NRC Twin Registry
To analyze cardiovascular disease mortality and total mortality in the NAS-NRC Twin Registry using a new methodology that allowed for censored observations of outcomes, environmental covariates, and unmeasured…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Diabetes Mellitus
- Trial name
- NCT00005266
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Renal Failure, Kidney Disease
Prevention of Serious Adverse Events Following Angiography
The purpose of this research study is to compare the effectiveness of intravenous isotonic sodium bicarbonate with intravenous isotonic sodium chloride and oral N-acetylcysteine (NAC) with oral placebo for the prevention of…
- Conditions
- Acute Renal Failure, Kidney Disease, Coronary Artery Disease
- Trial name
- PRESERVE (NCT01467466)
- Testing
- IV isotonic saline, IV isotonic bicarbonate, N-acetylcysteine
- Where
- 54 sites in United States, Australia and 2 more
- Volunteers
- 5,177 people
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases, Heart Diseases
Social Dominance, Gender, and Cardiovascular Reactivity
To examine biopsychosocial processes that might contribute to the associations among social dominance, gender, and cardiovascular reactivity,.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease
- Trial name
- NCT00005522
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease
Clopidogrel High Dose Evaluation for the Patient With Coronary Artery Disease in Japan
The purpose of this study is to evaluate the effect of high dose clopidogrel as the antiplatelet therapy on inhibition of platelet aggregation in Japanese patients scheduled for percutaneous coronary intervention due to ischemic…
- Trial name
- CHOICE (NCT01069302)
- Testing
- Clopidogrel
- Where
- Japan
- Volunteers
- 106 people
- Sponsor
- Takeshi Morimoto
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.