Clinical trials: Coronary Bypass
Coronary Artery Disease, Coronary Artery Bypass Graft Surgery
The Effect of Listening to Holy Quran Recital on the Incidence of Delirium Post-CABG
This study is planned to check the effect of holy Quran recital on the development of delirium after conronary artery bypass graft surgery (CABG).
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Graft Surgery, Delirium, Postoperative
- Trial name
- NCT06346990
- Testing
- Holy Quran Recital
- Volunteers
- 264 people
- Sponsor
- Applied Science Private University
Coronary Artery Disease, CABG
Clinimetric Properties of Performance Based Functional Outcome Measure After (CABG) Surgery
The purpose of this research is to determine which performance based functional outcome test among Time up and go test, Five times sit to stand test, 2 minute walk test and 6 minute walk test has the greatest significance in…
- Trial name
- NCT07060937
- Testing
- Physiotherapy Protocol
- Where
- 2 sites in Pakistan
- Volunteers
- 100 people
- Sponsor
- Riphah International University
Coronary Artery Bypass Graft Surgery (CABG), Radial Artery Grafts
Effect of Oral Isosorbide Mononitrate Plus Amlodipine Antispasm Therapy on Outcomes of Radial Artery Grafts After CABG
The goal of this clinical trial is to to evaluate the effect of oral isosorbide mononitrate plus amlodipine antispasm therapy on outcomes of radial artery grafts in patients underwent primary isolated CABG.
- Conditions
- Coronary Artery Bypass Graft Surgery (CABG), Radial Artery Grafts, Graft Failure
- Trial name
- ASRAB (NCT06730945)
- Testing
- Oral isosorbide mononitrate 4+ amlodipine
- Where
- China
- Sponsor
- Ruijin Hospital
Acute Coronary Syndrome
Effect of Glucose-insulin-potassium Solution on Myocardial Protection During Off-pump Coronary Bypass Surgery in Patients With Acute Coronary Syndrome
Patients undergoing multivessel off-pump coronary bypass surgery (OPCAB) inevitably experience cumulative ischemia-reperfusion injury at myocardium.
- Trial name
- NCT01384656
- Testing
- GIK solution
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Yonsei University
Coronary Artery Disease, Multivessel Coronary Artery Disease
Robotically-assisted Minimally-invasive Direct Coronary Artery Bypass With Stenting, Randomized Against Coronary Artery Bypass Graft Surgery
The study objective is to compare standard CABG to a hybrid revascularization strategy (RA-MIDCAB + PCI) in patients who have multi-vessel CAD and an indication for surgery, but who have a slightly higher risk of post-operative…
- Trial name
- ROBOT RCT (NCT06378775)
- Testing
- Coronary Artery Bypass Graft, Robotically-assisted minimally-invasive direct coronary artery bypass, Percutaneous Coronary Intervention
- Volunteers
- 80 people
- Sponsor
- Cardiology Research UBC
Heart; Surgery, Heart, Functional Disturbance as Result
The Role of Modified Ultrafiltration Following Open Heart Surgery
This study aims to investigate the effect of combining conventional ultrafiltration and modified ultrafiltration compared to conventional ultrafiltration alone in patients who underwent open heart surgery.
- Trial name
- NCT06085066
- Testing
- Conventional Ultrafiltration alone on Cardiopulmonary bypass, Conventional Ultrafiltration followed by Modified Ultrafitration on Cardiopulmonary bypass
- Where
- Indonesia
- Volunteers
- 38 people
- Sponsor
- Universitas Indonesia
Coronary Arterial Disease (CAD), Coronary Artery Bypass Graft (CABG)
Comparison of Oxygen Reserve Index and Spirometry in Predicting Respiratory Complications After Coronary Artery Bypass Surgery
Coronary artery disease (CAD) is one of the most common cardiac conditions, primarily caused by atherosclerosis. Studies have shown that environmental factors such as lifestyle, diet, genetics, and air pollution contribute to the…
- Conditions
- Coronary Arterial Disease (CAD), Coronary Artery Bypass Graft (CABG), Postoperative Pulmonary Complication
- Trial name
- NCT07063277
- Testing
- Preoperative Evaluation with ORI and Spirometry
- Where
- Turkey (Türkiye)
- Volunteers
- 142 people
- Sponsor
- Ankara Bilkent Sehir Hastanesi
Cardiopulmonary Bypass, Cardiac Surgery
Central and Peripheral Arterial Pressure Decoupling In Cardio-Pulmonary Bypass
Central and peripheral arterial pressure decoupling occurs in some clinical conditions like sepsis or cardiopulmonary bypass. This decoupling may leed to unsuitable decisions such as the use of catecholamines.
- Conditions
- Cardiopulmonary Bypass, Cardiac Surgery, Extracorporeal Circulation
- Trial name
- CAPD-CPB (NCT02652858)
- Testing
- Non-invasive blood pressure oscillometer (NIBP) implementation
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Heart Valve Diseases, Cardiopulmonary Bypass
Acupuncture Improves Sleep in Patients Undergoing Cardiopulmonary Bypass
Due to various causes, such as brain impairment, environment changes, anxious,et al. patients, who undergo cardiopulmonary bypass, often suffer from poor quality of sleep.
- Trial name
- NCT01231776
- Testing
- electronic acupuncture
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Acute Coronary Syndrome (ACS)
Effect of Perioperative Clopidogrel Responsiveness on Ischemic Outcome in Patients With Acute Coronary Syndrome Undergoing Off-pump Coronary Artery Bypass Surgery
The whole blood Thrombelastograph (TEG®) Platelet Mapping™ assay measures clot strength, maximal amplitude (MA), reflecting maximal platelet function, and detects the reduction in platelet function, presented as percentage…
- Trial name
- NCT02184884
- Testing
- MACE after OPCAB, without MACE after OPCAB
- Where
- South Korea
- Volunteers
- 195 people
- Sponsor
- Yonsei University
Kidney Failure, Acute, Acute Kidney Insufficiency
Minocycline to Prevent Acute Kidney Injury After Cardiac Surgery
This study proposes to investigate whether treatment with minocycline pre-operatively in patients with mild to moderate chronic kidney disease undergoing cardiac surgery will reduce the occurence of kidney injury.
- Trial name
- NCT00556491
- Testing
- minocycline
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Tarek M. El-Achkar
Coronary Disease
320 Multidetector Computed Tomography Prior to Coronary Artery Bypass Surgery
Recent advances in technology have resulted in the development of scanners that can n image the heart arteries within 10 to 20 minutes but without the need for admission to hospital or insertion of catheters.
- Trial name
- NCT01169948
- Testing
- Computed tomography scan
- Where
- United Kingdom
- Sponsor
- University of Edinburgh
Aortic Valve Replacement, Coronary Artery Bypass Grafting
Hemodynamic Assessment of Mosaic Ultra Stented Heart Valve in the Aortic Position
The special fixation methodology of the Mosaic Ultra stented procine bioprosthesis allows valves to maintain their natural leaflet structure and root geometry which prevents leaflet calcification and improves hemodynamic…
- Trial name
- NCT00477555
- Testing
- Aortic implantation of Mosaic Ultra porcine bioprosthesis
- Where
- 11 sites in Austria, Belgium and 3 more
- Volunteers
- 43 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Coronary Artery Disease
The Internal Thoracic Artery Skeletonization Study: A Paired, Within-Patient Comparison
The purpose of this study is to determine whether skeletonization of the internal thoracic artery leads to improved flow, increased length, improved sternal perfusion, and decreased pain and dysesthesia in patients undergoing…
- Trial name
- NCT00265499
- Testing
- Skeletonization of the internal thoracic artery
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Ottawa
Coronary Artery Disease Amenable to Bypass Graft Surgery
Graft Patency in Beating Heart Vs. Conventional CABG Using Cardiac CT
The purpose of this study is to compare graft patency rates following coronary artery bypass graft surgery performed by beating heart vs. conventional techniques using cardiac CT scanning to evaluate the bypass grafts.
- Trial name
- NCT00259493
- Testing
- Off-Pump Coronary Artery Bypass Graft Surgery
- Where
- Canada
- Volunteers
- 350 people
- Sponsor
- Trillium Health Centre
Blood Transfusion Associated Adverse Reactions
Antihistamine for Prevention of HTR After Blood Primed CPB
This study will be a randomized, double-blinded, placebo-controlled study conducted at a university hospital. Forty children undergoing elective repair of a congenital heart defect will be included.
- Trial name
- HTR - CPB (NCT07536152)
- Testing
- Antihestamine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kasr El Aini Hospital
Heart Failure, Heart Attack
IMPACT-CABG Trial: IMPlantation of Autologous CD133+ sTem Cells in Patients Undergoing Coronary Artery Bypass Grafting
Following myocardial infarct, cellular therapy is a potential approach to repopulate the injured myocardium, to treat heart failure and restore cardiac function.
- Conditions
- Heart Failure, Heart Attack, Coronary Artery Bypass Surgery
- Trial name
- IMPACT-CABG (NCT01467232)
- Testing
- Injection of autologous CD133+ stem cells at the time of coronary artery bypass grafting
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Coronary Artery Disease
Comparison of One-stop Hybrid Revascularization Versus Off-pump Coronary Artery Bypass for the Treatment of Multi-vessel Disease
The "one-stop" hybrid coronary revascularization combines minimally invasive direct coronary artery bypass (MIDCAB) and PCI to be performed in the hybrid operating suite, an enhanced operating room equipped with radiographic…
- Trial name
- NCT01034371
- Testing
- Minimally invasive direct coronary artery bypass, PCI-Drug eluting stents, Off-pump coronary artery bypass
- Where
- 2 sites in China
- Volunteers
- 400 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Disease, Sleep Disorder
The Effect of Eye Mask Applied on Patients Undergoing Coronary Artery Bypass Graft Surgery
Introduction: Coronary Artery Bypass Graft (CABG) performed with open heart surgery technique is a successful operation in the treatment of cardiovascular diseases.
- Conditions
- Coronary Artery Disease, Sleep Disorder, Pain, Postoperative
- Trial name
- NCT06010498
- Testing
- eye mask, standart care
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Pneumonia, Cardio/Pulm: Respiratory Failure
Lung Ultrasonography After Major Cardiac Surgery
Diagnosis of pneumonia remains difficult in intensive care unit (ICU), notably after cardiac surgery. Lung ultrasonography (LUS) has been successfully used for diagnosis of pneumonia, but its usefulness and reliability was never…
- Conditions
- Pneumonia, Cardio/Pulm: Respiratory Failure, Cardiopulmonary Bypass
- Trial name
- ECHOVAP (NCT03279887)
- Testing
- Lung Ultrasound
- Volunteers
- 51 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
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