Clinical trials: Coronary Bypass
Coronary Artery, Anxiety
The Effect of Diaphragmatic Breathing Exercise on Symptom Severity, Sleep Quality and Anxiety in CABG Patients.
Coronary artery bypass surgery (CABC) is a commonly performed surgical procedure for the treatment of blockages in the heart vessels. This surgical intervention aims to improve the blood circulation of the patients' heart muscle.
- Conditions
- Coronary Artery, Anxiety, Symptom, Sleep
- Trial name
- NCT06356896
- Testing
- diaphragmatic breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- KTO Karatay University
Mitral Valvular Heart Disease
Comparison of 6% Hydroxyethyl Starch 130/0.4 With 5% Albumin as Priming Solution for Cardiopulmonary Bypass
Comparison of 6% hydroxyethyl starch 130/0.4 with 5% albumin as priming solution for cardiopulmonary bypass
- Trial name
- NCT00978588
- Testing
- 6% hydroxyethyl starch 130/0.4 and 5% albumin
- Volunteers
- 36 people
- Sponsor
- Yonsei University
Coronary Artery Disease
Multicentre Radial Artery Patency Study: Results of Patency Beyond 5 Years After Coronary Artery Bypass Surgery
Bypass surgery is often required to treat severe coronary heart disease. Either arteries or veins can be used as bypass grafts. We wish to compare the long-term durability of the saphenous vein from the leg to that of the radial…
- Trial name
- RAPS - 5 years (NCT00187356)
- Testing
- Radial Artery and Saphenous Vein Grafts Randomized to either right coronary or left circumflex coronary artery territories
- Where
- 13 sites in Canada, New Zealand
- Volunteers
- 269 people
- Sponsor
- Sunnybrook Health Sciences Centre
CABG
Effects of Early Mobility Protocols in Cardiac ICU
In this study the investigator aim to find the effects of early mobility on different physical activity protocols in post CABG patients.
- Trial name
- NCT06029556
- Testing
- Mobility out of Bed, Ergometry in Bed
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Riphah International University
CAD - Coronary Artery Disease, CABG
Comparative Analysis of Analgesic Approaches in the Early Period After CABG
The goal of this clinical trial is to study postoperative analgesia in patients undergoing CABG. And learn if tafalgin (tyrosyl-D-arginyl-phenylalanyl-glycine amid) treats pain not inferiory then morphine.
- Conditions
- CAD - Coronary Artery Disease, CABG, Analgesia Assessment
- Trial name
- CABG-PAIN (NCT07451522)
- Testing
- Tafalgin (tyrosyl-D-arginyl-phenylalanyl-glycine amide), Morphine (+)
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Primorsky Regional General Hospital #1
Coronary Artery Disease
On-pump Versus Off-pump Coronary Artery Bypass Grafting , Short Term Outcomes , Sohag Experience
Coronary artery disease (CAD) and its sequlae, such as myocardial infarction, arrhythmia and heart failure, are among the leading causes of death around the world .
- Trial name
- NCT06069986
- Testing
- coronary artery bypass graft CABG
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Sohag University
Videolaryngoscopy
Laryngoscopy and Coronary Artery Bypass Graft Surgery
In this prospective, randomized, controlled trial, the purpose is to compare Macintosh laryngoscope, EzVision® video laryngoscope, McGrath® video laryngoscope and Storz® video laryngoscope in terms of hemodynamic response…
- Trial name
- VL (NCT06349005)
- Testing
- Tracheal intubation using Storz VL, Tracheal intubation using Macintosh laryngoscopy, Tracheal intubation using MacGrath VL
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Cardiac; Arteriosclerosis, Aortic Valve Disease
The Association Between Delivered Oxygen and Cerebral Impact During the Use of Cardiopulmonary Bypass.
Investigating the connection between delivered oxygen index and cerebral impact with COx (cerebral oximetry index) och cerebral injury markers during the routine use of cardiopulmonary bypass.
- Trial name
- NCT05620875
- Testing
- Cerebral injury markers, Cerebral oximetry index
- Where
- Sweden
- Volunteers
- 106 people
- Sponsor
- Uppsala University
Analgesia
NOL-Guided Superficial Parasternal Intercostal Plane Block Versus Erector Spinae Plane Block
This clinical trial focuses on an elaborate, propensity-matched, non-inferiority comparison of NOL-guided Superficial Parasternal Intercostal Plane Block (SPIPB) and Erector Spinae Plane Block (ESPB) within the context of…
- Trial name
- NESP-II (NCT06070701)
- Testing
- Superficial Parasternal Block (SIPB), Erector Spinae Plane Block (ESPB), General anesthetic
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu
Acute Coronary Syndrome, Coronary Bypass Stenosis
Coronary CT Angio Evaluating Graft Patency in ACS Patients Treated With DAPT or Single ASA After CABG (CoCAP)
The purpose of this study is to compare the presence of graft patency in single aspirin vs dual anti platelet therapy (DAPT) treatment including ticagrelor in patients with acute coronary syndrome (ACS) treated with coronary…
- Trial name
- NCT04783701
- Where
- 6 sites in Norway, Sweden
- Volunteers
- 360 people
- Sponsor
- University Hospital, Linkoeping
Platelet Function
Remote Ischemic Conditioning and Platelet Dysfunction
The purpose of this study is to evaluate the effects of remote ischemic conditioning on platelet function during off-pump coronary artery bypass surgery.
- Trial name
- NCT03125681
- Testing
- Remote ischemic conditioning, Control
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
Oxidative Stress, Systemic Inflammatory Response Syndrome
Inflammatory Response and Oxidative Stress in Cardiac Surgery: Min. Invasive vs. Conventional Extracorporeal Circulation
The goal of our research project is to measure and compare oxidative stress markers, and systemic inflammatory response in patients undergoing open heart surgery with either conventional or minimally invasive extracorporeal…
- Conditions
- Oxidative Stress, Systemic Inflammatory Response Syndrome, Extracorporeal Circulation; Complications
- Trial name
- NCT06477757
- Testing
- Minimally Invasive Extracorporeal Circulation, Conventional Extracorporeal Circulation
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- University Medical Centre Maribor
Cardiopulmonary Bypass, Lactate
Prognostic Value of Peak Lactate During Cardiopulmonary Bypass in Adult Cardiac Surgeries
Tissue hypoperfusion during cardiopulmonary bypass (CPB) affects cardiac surgical outcomes. Lactate, an end product of anaerobic glycolysis from oxygen deficit, is an obtainable marker of tissue hypoxia.
- Trial name
- NCT03934892
- Testing
- serum lactate
- Volunteers
- 97 people
- Sponsor
- Hualien Tzu Chi General Hospital
C.Surgical Procedure; Cardiac
Ketamine Pharmacokinetics in Children Having Heart Surgery
What are the pharmacokinetics of ketamine in infants and children requiring ketamine for induction of anesthesia for cardiac surgery that requires CPB? Specific Aim 1: To determine the pharmacokinetic parameters of a single…
- Trial name
- NCT00598195
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Coronary Artery Disease, Multivessel Coronary Artery Disease
Robotically-assisted Minimally-invasive Direct Coronary Artery Bypass With Stenting, Randomized Against Coronary Artery Bypass Graft Surgery
The study objective is to compare standard CABG to a hybrid revascularization strategy (RA-MIDCAB + PCI) in patients who have multi-vessel CAD and an indication for surgery, but who have a slightly higher risk of post-operative…
- Trial name
- ROBOT RCT (NCT06378775)
- Testing
- Coronary Artery Bypass Graft, Robotically-assisted minimally-invasive direct coronary artery bypass, Percutaneous Coronary Intervention
- Volunteers
- 80 people
- Sponsor
- Cardiology Research UBC
Postoperative Complications
Cardiac Surgery and Postoperative Organ Dysfunction
The aim of the study is to identify the correlation between ischaemia reperfusion injury and postoperative multiorgan damage during cardiopulmonary cardiac surgery; and to investigate biomarkers that can predict postoperative…
- Trial name
- NCT05529212
- Testing
- ischemic reperfusion injury
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Myocardial Infarction, Coronary Artery Bypass
Improving Cardiac Rehabilitation Exercise Using Target Heart Rate Trial
The goal of this clinical trial is to compare two types of exercise prescriptions in cardiac rehabilitation eligible older adults (60 years or older) with heart disease.
- Conditions
- Myocardial Infarction, Coronary Artery Bypass, Percutaneous Coronary Intervention, Heart Failure
- Trial name
- PACE SETTER (NCT05925634)
- Testing
- RPE (usual care), GXT+THHR (intervention)
- Where
- 2 sites in United States
- Volunteers
- 320 people
- Sponsor
- Baystate Medical Center
Post-cardiac Surgery, Inflammation
Cytokine Adsorption During Complex Cardiac Surgery: a Controlled Randomized Trial
This prospective single-centre randomized controlled trial aims at evaluating the safety and efficacy of hemoadsorption with HA-380® during cardio-pulmonary bypass in 40 patients undergoing complex cardiac surgery.
- Conditions
- Post-cardiac Surgery, Inflammation, Organ Dysfunction Syndrome, Cardiac Disease
- Trial name
- JACCS (NCT06512623)
- Testing
- Hemoadsoprtion
- Where
- Switzerland
- Volunteers
- 41 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Cardiopulmonary Bypass Surgery
Efficacy of Pathogen Inactivation Strategies for Platelet Transfusion
This is a prospective randomized clinical trial designed to determine the hemostatic ability of pathogen reduced platelet, when compared to non-pathogen reduced platelets suspended in platelet additive solution.
- Trial name
- NCT06535360
- Testing
- Platelet transfusion
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Maryland, Baltimore
Thoracic Surgery, Cardiopulmonary Bypass
Cerebral Autoregulation Monitoring During Cardiac Surgery
Neurological complications from cardiac surgery are an important source of operative mortality, prolonged hospitalization, health care expenditure, and impaired quality of life.
- Trial name
- NCT00981474
- Testing
- blood pressure maintenance based on cerebral blood flow autoregulation measurement, Control group
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- Northwestern University
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