Clinical trials: Coronary Ectasia
Marfan Syndrome
Study of the Efficacy of Losartan on Aortic Dilatation in Patients With Marfan Syndrome
The purpose of this study is to evaluate if losartan limits aortic dilatation in patients with Marfan syndrome.
- Trial name
- MARFANSARTAN (NCT00763893)
- Testing
- Losartan
- Where
- France
- Volunteers
- 303 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Heart Disease
A Study Assessing the Effect of RO4607381 on Vascular Function in Patients With Coronary Heart Disease (CHD) or CHD-Risk Equivalent Patients
This study will assess the safety, tolerability and efficacy of RO4607381 in patients with coronary heart disease (CHD) or CHD risk equivalents.
- Trial name
- NCT00655538
- Testing
- dalcetrapib
- Where
- 23 sites in Austria, France and 5 more
- Volunteers
- 476 people
- Sponsor
- Hoffmann-La Roche
Cardiovascular Diseases, Testicular Neoplasms
High-Intensity Aerobic Interval Training in Testicular Cancer Survivors
This study evaluates the impact of a supervised 12-week high-intensity aerobic interval exercise program (versus a self-directed exercise usual care group) on traditional and novel cardiovascular disease risk factors and…
- Trial name
- HIITTS (NCT02459132)
- Testing
- High-intensity aerobic interval exercise
- Volunteers
- 63 people
- Sponsor
- University of Alberta
Coronary Artery Disease
Evaluate Safety and Efficacy of Alveo HP Balloon Dilatation Catheter for Balloon Dilatation of Coronary Artery Stenosis
This is a prospective, multi-center, single-group study aims to evaluate the safety and efficacy of Alveo HP Balloon Dilatation Catheter for balloon dilatation of coronary artery stenosis.
- Trial name
- NCT05998252
- Testing
- Alveo HP Balloon Dilatation Catheter
- Where
- 3 sites in China
- Volunteers
- 60 people
- Sponsor
- BrosMed Medical Co., Ltd
Coronary Artery Disease
Efficacy and Safety of Sirolimus-coated Coronary Balloon Dilatation Catheter for Coronary Small Vessels
To evaluate the safety and efficacy of a sirolimus-coated coronary balloon dilatation catheter for the treatment of small vessel lesions of primary coronary arteries.
- Trial name
- NCT06345209
- Testing
- Sirolimus-coated Coronary Balloon Dilatation Catheter, Drug-coated Coronary Balloon Dilatation Catheter
- Volunteers
- 236 people
- Sponsor
- BrosMed Medical Co., Ltd
Ventricular Function, Left
Assessment of Cardiac Involvement of Common Cold in High Performing Athletes by Cardiac Magnetic Resonance Imaging (MRI)
Cardiovascular magnetic resonance (CMR) imaging will be used to assess the impact of common colds and physical training in high-performing athletes. Healthy individuals from the general public will serve as a comparison group.
- Trial name
- NCT00739895
- Testing
- Cardiac magnetic Resonance study, Blood testing
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Endothelial Function of Saphenous Vein Grafts
Investigation of Endothelium in Saphenous Vein Grafts
This is a single center prospective study of 30 patients undergoing elective heart bypass surgery (CABG) with at least two vein grafts from the leg (SVG).
- Trial name
- NCT01510821
- Testing
- Use of Maquet Vasoshield Pressure-limiting syringe on SVG, Use of non-regulated syringe on SVG
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Aortic Aneurysm, Thoracic, Aortic Dissection
Point-of-Care Focused Cardiac Ultrasound in Assessing the Thoracic Aorta
The purpose of this prospective study is to compare point-of-care focused cardiac ultrasound (FOCUS) to thoracic computed tomographic angiography (CTA) in the measurement of ascending aortic dimensions.
- Trial name
- NCT01671618
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Yale University
Heart Failure, Heart Dilation
The Use of Blood Biochemical Markers for Diagnostics of Heart Muscle Diseases
The aim of the study is to determine the analytical characteristics of the microRNA enzymatic immunoassay (miREIA) method and to determine various relations among miRNA biomarkers and heart failure (HF) with reduced ejection…
- Conditions
- Heart Failure, Heart Dilation, Left Ventricular Hypertrophy
- Trial name
- NCT05726695
- Testing
- microRNA test, Heart ultrasound examination
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital Ostrava
Coronary Artery Disease
Biomarkers for Cardiovascular Disease
Biomarkers for Cardiovascular Disease Summary: This study will examine the function of the lining cells of blood vessels and measure substances in the blood to see how they relate to various blood tests, including new tests under…
- Trial name
- NCT00109018
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Turner Syndrome
Aortic Dimensions in Turner Syndrome
An observational study of 102 women with Turner syndrome followed for 6 years with a two-yearly examination including ECHO, MRI of the heart and 24 ambulatory blood pressure.
- Trial name
- NCT00624949
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Coronary Artery Disease
Rise Semi Compliant Balloon Study in Patient With CAD
Single arm, prospective, multi-center, trial designed to enrol approximately 66 patients. All patients will undergo PCI using at least one RISE SC balloon as per routine clinical practice and will be followed until discharge for…
- Trial name
- NCT04796038
- Testing
- Balloon dilatation
- Where
- 3 sites in Switzerland
- Volunteers
- 67 people
- Sponsor
- Biosensors Europe SA
Aortic Stenosis, TAVI(Transcatheter Aortic Valve Implantation)
Dilation Optimisation for Uniform Bioprosthetic Leaflet Expansion
The goal of this clinical trial is to discover if routine 'double tap' balloon post-dilation improves valve expansion and clinical outcomes in adults undergoing Transcatheter Aortic Valve Implantation (TAVI) with the SAPIEN…
- Trial name
- ACE-DOUBLE (NCT07430267)
- Testing
- 'Double tap' balloon post-dilation
- Where
- 3 sites in Australia
- Volunteers
- 250 people
- Sponsor
- The Alfred
Coronary Artery Ectasia
Arrhythmogenic Risk Assessment in Coronary Artery Ectasia Patients
The investigators thought to explore arrhythmias outcome - hidden arrhythmias, ECG features: Tp-Te interval and Tp-Te/QTc ratio, fQRS among patients with coronary artery ectasia as compared to normal coronary artery patients.
- Trial name
- NCT05106530
- Testing
- Holter, ECG
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Healthy
Radial Artery Dilation Study: The Effect of Topical Administration of Nitroglycerin and Lidocaine Versus Lidocaine Alone of the Radial Artery Diameter
The radial artery, which is located on the outer side of the forearm, can be used in interventional procedures, such as cardiac catheterization, to provide access to the arterial blood supply.
- Trial name
- NCT00686231
- Testing
- Nitroglycerin 15mg, Nitroglycerin 30mg, Lidocaine 20mg
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
ST-Elevation Myocardial Infarction
Brasilia Heart Study
BHS is a cohort study of consecutive myocardial infarction (MI) patients admitted within the first 24 hours of symptoms and has been ongoing since May of 2006.
- Trial name
- BHS (NCT02062554)
- Where
- Brazil
- Volunteers
- 1,000 people
- Sponsor
- University of Campinas, Brazil
Coronary Artery Disease, Ischemic Heart Disease
Essential Pro Study ( rEPIC04E-HK )
Single center, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of Essential Pro to meet EU Medical Device regulation (MDR) requirements in all…
- Trial name
- rEPIC04E-HK (NCT06631157)
- Testing
- Essential pro
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Fundación EPIC
Atrial Fibrillation, Left Atrial Dilatation
His-pacing and AV-node Ablation vs. Pulmonary Vein Isolation for Atrial Fibrillation
Objective To investigate if conduction system pacing ((CSP) i.e. atrioventricular node ablation + His bundle pacing or Left Bundle Branch pacing) is as good as (or better than) atrial fibrillation ablation with pulmonary vein…
- Trial name
- His-PAAF (NCT04512586)
- Testing
- Conduction System pacing and AV node ablation, Atrial fibrillation ablation by pulmonary vein isolation
- Where
- 4 sites in Sweden
- Volunteers
- 45 people
- Sponsor
- Region Skane
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Marfan Syndrome
Randomized, Double-blind Study for the Evaluation of the Effect of Losartan Versus Placebo on Aortic Root Dilatation in Patients With Marfan Syndrome Under Treatment With Beta-blockers
To study the effect of losartan (an angiotensin receptor blocker-ARB) on aortic root growth in patients with Marfan syndrome, already treated with beta-blockers (BB). The effect of losartan will be compared to placebo.
- Trial name
- NCT00782327
- Testing
- Losartan
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- University Hospital, Ghent