Clinical trials: Coronary Ectasia
Thoracic Aorta Dilatation, Marfan Syndrome
Thoracic Aortic Dilatation Syndromes
Aortic dilatation syndromes are comprised by a group of different syndromes, of which Marfan syndrome is the best described. Many of the aorta dilatation associated syndromes are heritable connective tissue disorders but some…
- Trial name
- NCT02111668
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Aarhus
Atherosclerosis, Cardiovascular Disease
A Prospective Study on Predictive Value of Non-Invasive Atherosclerotic Measurements in Elderly Chinese
The purpose of this study is to determine whether non-invasive atherosclerotic measurements (baPWV, IMT, FMD, CACS, ABI) are valuable predictors for cardiovascular events in elderly.
- Trial name
- NCT01208116
- Testing
- Cardiovascular events
- Where
- China
- Volunteers
- 1,290 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University General Hospital
Healthy, Healthy Participants
Acute Effects of Structured Exercise and Static Stretching on Vascular Function, Neuromuscular Performance, and Metabolic Regulation in Adults
This experimental study investigates the acute cardiovascular and vascular responses to a single session of resistance training, with and without additional static stretching, compared with a resting control condition.
- Conditions
- Healthy, Healthy Participants, Healthy Subjects (HS), Resistance Training Adaptation
- Trial name
- NCT07364149
- Testing
- Resistance Training, Resistance training + Static Stretching
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Cardiomyopathy
New Horizons for the Treatment of Cardiomyopathy in Children
Collecting mono nuclear cells from the patient's blood after a course of granulocyte stimulation then injecting them into the weak heart muscle measuring the heart function at the beginning and after 2.4.6 months to assess the…
- Trial name
- NCT04893629
- Testing
- mono nuclear cells injection, Digoxin+furosemide+captopril
- Where
- Syria
- Volunteers
- 22 people
- Sponsor
- Damascus University
ST-Elevation Myocardial Infarction
Brasilia Heart Study
BHS is a cohort study of consecutive myocardial infarction (MI) patients admitted within the first 24 hours of symptoms and has been ongoing since May of 2006.
- Trial name
- BHS (NCT02062554)
- Where
- Brazil
- Volunteers
- 1,000 people
- Sponsor
- University of Campinas, Brazil
Atrial Fibrillation, Hypertension,Essential
Left Atrial Enlargement: A Crucial Indicator for Identifying Atrial Fibrillation in Patients With Hypertension
Based on the data of inpatients with hypertension and a cross-sectional study with a large sample size, this study aims to find the early warning value of the left anteroposterior atrial diameter for the possible occurrence of…
- Conditions
- Atrial Fibrillation, Hypertension,Essential, Left Atrial Dilatation
- Trial name
- NCT06359873
- Testing
- CHA2DS2-VASc score, C2HEST score, and left atrial diameter (LAD)
- Where
- China
- Volunteers
- 58,427 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Aortic Stenosis
Transfemoral Transcatheter Aortic Valve Implantation With or Without Predilation of the Aortic Valve (EASE-IT TF)
Prior to the deployment of transcatheter heart valves (THV), balloon aortic valvuloplasty (BAV) is often performed under rapid right ventricular pacing (burst >180 bpm) with the induction of a functional cardiac arrest for up to…
- Trial name
- EASE-IT-TF (NCT02760771)
- Testing
- with BAV, without BAV
- Where
- Germany
- Volunteers
- 196 people
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Coronary Disease
Randomized Trial of Coronary Angioplasty for de Novo Lesions in sMall vesSElS With Drug Eluting Balloon.
Significant lesions in small coronary arteries are frequently found (35%-50%) in patients with coronary artery disease. Independently of the type of coronary angioplasty the restenosis and the need for repeat revascularization…
- Trial name
- RAMSES (NCT01722799)
- Testing
- Drug elluting Balloon (DEB), Drug elluting coronary stent (DES)
- Where
- Spain
- Volunteers
- 97 people
- Sponsor
- Andres Iñiguez Romo, MD, PhD
Heart Failure
Safety Study of the Ventricular Partitioning Device (VPD) Implant System in Heart Failure Patients
The CardioKinetix Ventricular Partitioning Device (VPD) is intended to isolate the malfunctioning portion of the left ventricle in patients with symptoms of heart failure due to ischemic heart disease.
- Trial name
- PARACHUTE (NCT00573560)
- Testing
- VPD Implant System
- Where
- 7 sites in United States, Serbia
- Volunteers
- 20 people
- Sponsor
- CardioKinetix, Inc
Coronary Artery Ectasia
A New Classification and Interventional Therapy for Coronary Artery Ectasia
This study is aim to present a new classification for coronary artery ectasia and find the best interventional therapy for different types of patients were treated and studied.
- Trial name
- NCIPCAE (NCT04265989)
- Testing
- Single BMS, Single or Double BMS, BMS+DES
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Disease
Optimization of Percutaenous Coronary Intervention With Liberal Use of Post-dilatation
To achieve optimal long-term clinical results after percutaneous coronary intervention (PCI), adequate deployment of stents is essential.
- Trial name
- OPTIMIZE-PCI (NCT06558474)
- Testing
- Liberal post-dilatation strategy during PCI
- Where
- Netherlands
- Volunteers
- 12,000 people
- Sponsor
- Cathreine BV
Polynesian Bronchiectasis
Bronchi Dilation in Polynesian Patients: Monocentric Retrospective Study
The study hypothesis is that dilations of idiopathic bronchi are particularly common in French Polynesia, and that there are arguments in favour of an underlying genetic factor.
- Trial name
- NCT04798950
- Where
- French Polynesia
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Myocardial Infarction
Prevalence and Long-term Impact of Non-atherosclerotic CAD
Despite a relatively high prevalence of non-atherosclerotic coronary artery disease (NACAD) among young women, the majority of these abnormalities were misdiagnosed in this population, and thus treatments were not targeted…
- Trial name
- PRYME (NCT01479140)
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Cardiology Research UBC
Coronary Ectasia, Microbial Disease
The Relationship Between Microbiota and Coronary Ectasia
Introduction: It is now known that the microbiota is far beyond the microbial communities living in certain parts of our body and functions like a metabolic organ.
- Trial name
- NCT06384703
- Testing
- Taking blood for kit study
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Konya Beyhekim Training and Research Hospital
Ventricular Function, Left
Assessment of Cardiac Involvement of Common Cold in High Performing Athletes by Cardiac Magnetic Resonance Imaging (MRI)
Cardiovascular magnetic resonance (CMR) imaging will be used to assess the impact of common colds and physical training in high-performing athletes. Healthy individuals from the general public will serve as a comparison group.
- Trial name
- NCT00739895
- Testing
- Cardiac magnetic Resonance study, Blood testing
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Coronary Artery Disease
Effect of BNP (Brain Natriuretic Peptides) on Endothelial Dysfunction Induced by Coronary Angioplasty
Patients receiving BNP or nitroglycerin (IV) during the angioplasty procedure. 24 h after the procedure, vascular reactivity will be re-examined using the brachial artery flow-mediated dilatation study.
- Trial name
- NCT00262574
- Testing
- Nesiritide,
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Coronary Artery Disease
Turkish Isolated Coronary Ectasia Registry: The T-ICE Registry
The T-ICE study is a prospective, observational study aiming to have information about the treatment and long-term prognosis of patients with isolated coronary artery ectasia.
- Trial name
- T-ICE (NCT05897333)
- Where
- Turkey (Türkiye)
- Volunteers
- 3,000 people
- Sponsor
- Gazi University
Marfan Syndrome
Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome
Marfan syndrome is a hereditary connective tissue disorder. Many individuals with this condition die because of the associated heart and blood vessel abnormalities.
- Trial name
- NCT00429364
- Testing
- Losartan Potassium, Atenolol
- Where
- 26 sites in United States, Belgium and 1 more
- Volunteers
- 608 people
- Sponsor
- Carelon Research
Mitral Valve Regurgitation, Left Atrium Dilatation and Hypertrophy
Pilot Study of Lovaza (Omega 3 Fatty Acids) to Improve Cardiac Antioxidant/Anti-inflammatory Profile Before Cardiac Surgery
In the absence of treatment, severe mitral valve regurgitation (MR) results in left atrium (LA) dilatation and hypertrophy, followed ultimately by left ventricular dysfunction and heart failure.
- Conditions
- Mitral Valve Regurgitation, Left Atrium Dilatation and Hypertrophy, Mitochondrial Dysfunction in the Heart, Cardiomyocyte Apoptosis
- Trial name
- NCT01046604
- Testing
- Lovaza group
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- East Carolina University
Neurological Diseases, Heart or Respiratory Failure,, Sepsis, Trauma.
Effects of Tracheal Intubation on Ventilation With a Laryngeal Mask During Percutaneous Dilatation Tracheostomy
The length of tracheal intubation may affect the subsequent ventilation with a laryngeal mask during percutaneous tracheostomy.
- Trial name
- NCT00771784
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Padova