Clinical trials: Coronary Microvascular Perfusion in Patients With Ischemic Heart Disease
Angina Patients With Non-obstructive Coronary Artery Disease, Coronary Microvascular Disease
Study Targeting Myocardial Perfusion and Symptom Relief in Women With SGLT2 Inhibitors (STRONG)
The goal of this clinical trial is to that Sodium-glucose cotransporter 2 inhibitors treatment will improve Coronary Microvascular Disease with anginal symptoms associated with non-obstructive coronary disease in women.
- Conditions
- Angina Patients With Non-obstructive Coronary Artery Disease, Coronary Microvascular Disease, Coronary Microvascular Dysfunction (CMD)
- Trial name
- STRONG (NCT06600178)
- Testing
- Brenzavvy (bexagliflozin), 20 mg Oral Tablet
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Virginia
Microcirculatory Perfusion, ST Elevation Myocardial Infarction
Deferred or Immediate Stent Implantation Based on Microvascular Function in STEMI
Timely percutaneous coronary intervention (PCI) with stenting implantation is the current standard treatment for patients with ST-segment elevation myocardial infarction (STEMI).
- Trial name
- SALVAGE (NCT03581513)
- Testing
- Deferred or Immediate Stent Implantation
- Where
- 8 sites in China
- Volunteers
- 629 people
- Sponsor
- Harbin Medical University
Myocardial Infarction
Myocardial Perfusion Study to Detect Coronary Microvascular Abnormality in Diabetic Patients With Nonfatal Myocardial Infarction
The goal of this study is to use MCE (myocardial contrast/perfusion echocardiography) to study and compare short/long term change of myocardial perfusion abnormality and cardiac outcome in diabetic patients after nonfatal MI…
- Trial name
- GEMyCE 1 (NCT01749683)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- State University of New York - Upstate Medical University
Coronary Microvascular Perfusion in Patients With Ischemic Heart Disease
PGE1 Improves Coronary Microcirculation Dysfunction in Patients With CAD and Diabetes
This study is undertaken to determine if intravenous Lipo-PGE1 therapy would improve coronary microvascular perfusion in patients with ischemic heart disease by CMRI.
- Trial name
- NCT03159559
- Testing
- Lipo-PGE1
- Volunteers
- 60 people
- Sponsor
- Tongji Hospital
ST-segment Elevation Myocardial Infarction
Efficacy and Safety Study of Deferred Stenting in Patients With STEMI
It is known that no reflow phenomenon by microvascular obstruction after revascularization in STEMI increase infarct size, cardiac remodeling, and a risk of late mortality.
- Trial name
- INNOVATION (NCT02324348)
- Testing
- Deferred coronary stenting, Immediate coronary stenting
- Where
- South Korea
- Volunteers
- 114 people
- Sponsor
- Korea University Anam Hospital
Ischemic Heart Disease
Hyperbaric Oxygen Therapy in Patients With Chronic Stable Ischemic Heart Disease: An Option for Therapeutic Angiogenesis?
Hyperbaric oxygen therapy (HBOT) is proposed as a possible in vivo angiogenic stimulator for improving microvascular myocardial perfusion and anginal symptoms as assessed by myocardial perfusion imaging and angina questionnaire…
- Trial name
- NCT02760394
- Testing
- HBOT
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Assaf Harofeh MC