Clinical trials: Coronary Patient
Heart Failure With Reduced Ejection Fraction (HFrEF)
Effectiveness of Video Monitoring and Care Transition for Heart Failure Patients (EVIT-HF): Randomized Clinical Trial
The goal of this clinical trial is to measure the effectiveness of video monitoring associated with the transition of care for patients with heart failure.
- Trial name
- EVIT-HF (NCT06731166)
- Testing
- self-care
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- Federal University of Uberlandia
Acute Myocardial Infarction
Safety Study of AMI MultiStem® to Treat Heart Attacks
The purpose of this study is to determine if escalating doses of AMI MultiStem® delivered by catheter can safely be given to patients that have had a recent heart attack treated with stent implantation.
- Trial name
- NCT00677222
- Testing
- AMI MultiStem®
- Where
- 7 sites in United States
- Volunteers
- 25 people
- Sponsor
- Healios K.K.
Acute Decompensated Heart Failure
DORAYA-HF Early Feasibility Study
The study objective is to evaluate the feasibility of the Doraya Catheter and measure clinical performance and safety endpoints, in ADHF patients deemed to have insufficient diuretic response.
- Trial name
- NCT05206422
- Testing
- Doraya Catheter
- Where
- 14 sites in United States
- Volunteers
- 21 people
- Sponsor
- Revamp Medical Inc.
Type 2 Diabetes Mellitus, Coronary Artery Disease
DARE: Diabetes in cArdiac REhabilitation
The aim of the DARE study is to see whether strict glycemic control during cardiac rehabilitation may ameliorate the improvement of exercise capacities (VO2 peak, peak workload, ventilatory threshold)in patients with type 2…
- Trial name
- NCT00354237
- Testing
- Conventional antidiabetic treatment, Intensive insulin treatment
- Where
- 12 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Diabetes Mellitus, Congestive Heart Failure
Homing in on Health: Study of a Home Delivered Chronic Disease Self Management Program
The purpose of the study is to determine the effectiveness of a home-delivered variant of the chronic disease self management program in improving health outcomes in patients with chronic conditions.
- Conditions
- Diabetes Mellitus, Congestive Heart Failure, Arthritis, COPD
- Trial name
- NCT00263939
- Testing
- Homing in on Health
- Where
- United States
- Volunteers
- 415 people
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Aortic Stenosis, Amyloid
Atrial Amyloid May Influence Outcomes in Patients Undergoing Surgical Aortic Valve Replacement
Background (Context): Some older adults who undergo surgery to replace a narrowed heart valve (called aortic stenosis) may also have small protein deposits in their heart.
- Trial name
- AORTICMARKER (NCT07105501)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Germans Trias i Pujol Hospital
Coronary Artery Disease
Cangrelor Prasugrel Transition Study
To demonstrate that patients treated with cangrelor can be directly switched to oral prasugrel and that patients treated with prasugrel can be switched to cangrelor without a significant decrease in the extent of inhibition of…
- Trial name
- NCT01852019
- Testing
- Cangrelor, Prasugrel
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The Medicines Company
Acute Chest Pain
Early Cardiac Computed Tomography (CT) In Patients Admitted With Acute Chest Pain
This is a randomised trial comparing early Cardiac Computed Tomography (CCT) to current standard practice for diagnosis of acute chest pain in patients at low to intermediate risk of having coronary artery disease (CAD), in a UK…
- Trial name
- EXACCT (NCT00767065)
- Testing
- Cardiac Computed Tomography, Standard care
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Aortic Stenosis, Altitude
Short-term Exposure to High Altitude in Patients With Asymptomatic Aortic Stenosis
Aortic stenosis is a common disease with increasing prevalence due to an aging population. Aortic valve replacement is indicated for symptomatic severe aortic stenosis.
- Trial name
- ASALT (NCT06894550)
- Testing
- Participants will be escorted to high altitude and undergo a series of test
- Where
- Switzerland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Chronic Heart Failure
Muscle Afferent Feedback Effects in Patients With Heart Failure
The purpose of the study is to find out more about the mechanism by which neural feedback from the working muscle affects the development of central fatigue during exercise.
- Trial name
- NCT01919918
- Testing
- Muscle Contraction with Metabolite Solution Administration
- Where
- 2 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Utah
Ischemic Heart Disease
Ranolazine for Improving Symptoms of Palpitations
Patients with ischemic heart disease often report multiple symptoms, including angina and palpitations. Ranolazine has antiarrhythmic effects which are largely a result of the drug's effect on multiple ion channels.
- Trial name
- RYPPLE (NCT01495520)
- Testing
- Ranolazine
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
Aortic Valve Disease, Heart Valve Prosthesis Implantation
Comparison of Antithrombotic Treatments After Aortic Valve Replacement. Rivaroxaban: A New Antithrombotic Treatment for Patients With Mechanical Prosthetic Aortic Heart Valve.
Objectives Primary objective: To determine if rivaroxaban (Xarelto) is feasible and safe for prevention of major complications in patients undergoing a mechanical aortic heart valve replace-ment.
- Conditions
- Aortic Valve Disease, Heart Valve Prosthesis Implantation, Anticoagulants
- Trial name
- CATHAR (NCT02128841)
- Testing
- Rivaroxaban
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Myocardial Infarction, Heart Failure
Personalised Risk scOre For Implantation of Defibrillators in Patients With Reduced LVEF≤35% and a Low Risk for Sudden Cardiac Death
The objective of the study is to demonstrate that in post-MI patients with symptomatic heart failure who receive optimal medical therapy for this condition, and with reduced LVEF ≤ 35% but low risk for SCD according to a…
- Conditions
- Myocardial Infarction, Heart Failure, Sudden Cardiac Death
- Trial name
- PROFID-Reduced (NCT04540354)
- Testing
- Optimal Medical Therapy (OMT), Implantable cardioverter-defibrillator (ICD)
- Sponsor
- Helios Health Institute GmbH
Congenital Heart Disease in Children
Cardiac Simulator for Surgical Planning
The goal of this clinical trial is to learn if a computer software program (cardiac simulator) for surgical planning will lead to improvements in patient care by decreasing the incidence of unsuccessful interventions and…
- Trial name
- NCT06373705
- Testing
- Cardiac simulator
- Volunteers
- 275 people
- Sponsor
- Stanford University
Heart Transplantation
Haemoadsorption During Heart Transplantation
To investigate whether the use of haemoadsorption (HA) on cardiopulmonary bypass during heart transplantation (HTX) has an effect on circulating cytokine levels for the first 120 hours after HTX and induces a decreased…
- Trial name
- CytoSorbHTX (NCT05270902)
- Testing
- CytoSorb Adsorber
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Critically Ill, Cardiac Disease
Respired Gases in Patients Post Cardiac Surgery
Certain diseases relating to the heart can only be definitively treated with surgery. When untreated, these can lead to heart failure with a lack of supply of oxygen-rich blood to the tissues, leading to damage to other organs.
- Conditions
- Critically Ill, Cardiac Disease, Mitral Valve Disease
- Trial name
- REGAPS (NCT05531253)
- Testing
- Data collection using the Optical Gas Analyser
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- University of Oxford
Type II Diabetes
Type II Diabetes Influence on Left Ventricular Remodeling and Outcomes in Patients Undergoing Aortic Valve Replacement Surgery.
This project focuses on the physiopathology of left ventricular remodeling associated with type II diabetes in patients with aortic valve stenosis referred for surgical aortic valve replacement.
- Trial name
- DIAPASON (NCT01862237)
- Testing
- Intervention
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Congenital Heart Disease, Single-ventricle
Clinical Characteristics and Associations of the "Good Fontan" Patient
This study aims to determine what are some of the clinical characteristics and associations of Fontan patients who are doing well, as well as how accurate cardiology providers are at predicting the likelihood of future adverse…
- Trial name
- NCT03470428
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Boston Children's Hospital
Heart Failure With Preserved Ejection Fraction, Iron Deficiencies
The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life
This study will address whether the additional use of Ferric Derisomaltose on top of standard care will improve exercise capacity and quality of life in patients with acute heart failure and iron deficiency.
- Conditions
- Heart Failure With Preserved Ejection Fraction, Iron Deficiencies, Acute Heart Failure
- Trial name
- COREVIVE-HFpEF (NCT05991128)
- Testing
- Ferric derisomaltose
- Where
- China
- Volunteers
- 170 people
- Sponsor
- China-Japan Friendship Hospital
Acute Coronary Syndromes
Impact of Atorvastatin Versus Rosuvastatin on 25 Hydroxy Vitamin D Levels in Patients With Acute Coronary Syndrome
there will be 2 groups of patients with acute coronary syndrome. The patients will receive one of the 2 study drugs and impact on raising Vitamin D level will be seen after 6 months
- Trial name
- NCT06765265
- Testing
- Rosuvastatin 20 mg/day, Atorvastatin 40 mg
- Where
- Pakistan
- Volunteers
- 152 people
- Sponsor
- King Edward Medical University
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