Clinical trials: Coronary Patient
Diabetes Mellitus, Type 2, Diabetic Angiopathies
Effect of HMP on Diabetic Microangiopaemia in T2DM
The study mainly investigates the therapeutic effect of Heart-Protecting Musk Pill (HMP) on patients with diabetic microangiopathy.
- Trial name
- NCT05095922
- Testing
- Heart-Protecting Musk Pill, Valsartan Capsules, Calcium Dobesilate Capsules
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Affiliated Hospital of Nantong University
Cardiac Surgery
Serial Measurement of a Plasma Stroke Biomarker Panel in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass
The purpose of this study is to investigate changes in new plasma stroke biomarker panel in patients undergoing cardiac surgery with the use of cardiopulmonary bypass.
- Trial name
- Stroke08 (NCT00812656)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Klinikum Ludwigshafen
Heart Failure
Prolonged Intravenous Therapy Versus Early Initiation of an Oral Loop Diuretic in Decompensated Heart Failure
The goal of this clinical study is to compare treatment regimens of loop diuretics in patients with decompensated heart failure.
- Trial name
- NCT05652322
- Testing
- Furosemide Pill 150% equivalent iv dose, Furosemide Pill 200% equivalent iv dose, Furosemide Injection
- Where
- 3 sites in Poland
- Sponsor
- Jan Kochanowski University
Fluid Overload, Organ Edema
"The Effect of Reduced Fluid Load After Cardiac Surgery"
The purpose of this study is to verify that an infusion of hypertonic saline/colloids during cardio-pulmonary-bypass will reduce fluid overload and organ edema for cardiac patients with expected long-CPB-time.
- Conditions
- Fluid Overload, Organ Edema, Organ Function
- Trial name
- NCT01438502
- Testing
- HyperHAES® (hypertonic saline/HES)
- Sponsor
- Haukeland University Hospital
Congestive Heart Failure
EarlySense Monitoring Device Evaluation on CHF Patients
CHF patients will be monitored using EarlySense ES-16 device and will simultaneously fill diaries and log their weight daily. The data collected and analyzed by the ES-16 device will be correlated with the CHF status data.
- Trial name
- NCT00382746
- Testing
- EarlySense monitoring device
- Where
- Israel
- Sponsor
- EarlySense Ltd.
Atrioventricular Block
RandomIsed sTudy of Physiologic cArdiac stimuLation in patIents With Atrio-ventricular Conduction Disease
Study objective is to assess whether stimulation of the conduction system reduces cardiac decompensation events in patient follow-up, and how applicable this is in clinical practice and also to determine the impact of the studied…
- Trial name
- ITALIA (NCT07279870)
- Testing
- Conduction System Pacing (CSP), Right Ventricular (RV) Pacing
- Where
- 14 sites in Italy
- Volunteers
- 1,260 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Diabetes Mellitus, Type 2, Cardiac Surgery
Dapagliflozin Therapy In Cardiac Surgery
This randomized controlled trial is to assess the effects of perioperative dapagliflozin on type 2 diabetic patients undergoing cardiac surgery
- Trial name
- NCT05621551
- Testing
- Dapagliflozin
- Where
- China
- Volunteers
- 178 people
- Sponsor
- China National Center for Cardiovascular Diseases
Hypertension, Ischemic Heart Disease
Participatory Patient Care Planning in Primary Care
In the aging population, the prevalence of chronic diseases and multimorbidity has become common. Therefore, the planning and coordination of care have become more important.
- Conditions
- Hypertension, Ischemic Heart Disease, Diabetes Mellitus
- Trial name
- 4PHC (NCT02992431)
- Testing
- Participatory patient care planning, Usual care
- Where
- Finland
- Volunteers
- 600 people
- Sponsor
- Kuopio University Hospital
Anemia, Aortic Stenosis
Erythropoietin + Iron Therapy for Anemic Patients Undergoing Aortic Valve Replacement
The objective of the study is to evaluate the efficacy of Erythropoietin (EPO) (+ iron) in reducing the rate of red blood cell transfusion requirements in patients with aortic stenosis undergoing transcatheter aortic valve…
- Trial name
- EPICURE (NCT02390102)
- Testing
- Erythropoietin
- Where
- Canada
- Volunteers
- 117 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Acute Myocardial Infarction, Percutaneous Coronary Intervention
CardiOvascular Risk and idEntificAtion of Potential High-risk Population in Acute Myocardial Infarction II (COREA-AMI II)
This study is intended to provide contemporary data on the residual cardiovascular risk in all consecutive patients with acute myocardial infarction, especially in patients who survived stably within one-year after percutaneous…
- Conditions
- Acute Myocardial Infarction, Percutaneous Coronary Intervention, Major Adverse Cardiovascular Events, Bleeding
- Trial name
- NCT02806102
- Testing
- Percutaneous coronary intervention, Dual-antiplatelet therapy
- Where
- 2 sites in South Korea
- Volunteers
- 13,000 people
- Sponsor
- Seoul St. Mary's Hospital
Atrial Fibrillation
HERA FIb Registry for Patients With Atrial Fibrillation
The single-center HERA AFIb registry was created to assess real-world prevalence, demographic characteristics and management of patients with atrial fibrillation (AF) in the era of novel oral anticoagulant regimes (NOAC)…
- Trial name
- NCT05995561
- Testing
- no intervention is planned.
- Where
- Germany
- Volunteers
- 12,297 people
- Sponsor
- University Hospital Heidelberg
Heart Failure，Congestive
Left Ventricular Dyssynchrony in Multipole Pacing
Left ventricular dyssynchrony will be assessed by echocardiography using different programming of an implantable cardioverter defibrillator.
- Trial name
- NCT03187470
- Testing
- Different programming of a CRT defibrillator
- Where
- Germany
- Volunteers
- 41 people
- Sponsor
- Adnan Kastrati, MD
Systemic Sclerosis, Scleroderma
Cardiac Safe Transplants for Systemic Sclerosis
This study is designed to treat systemic sclerosis (scleroderma) patients with an autologous stem cell transplant using a regimen of immune suppressant drugs and chemotherapy that is less toxic to your heart.
- Trial name
- CAST (NCT03593902)
- Testing
- Rituximab, Fludarabine, Cyclophosphamide
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Northwestern University
Postoperative Quality of Recovery, Postoperative Quality of Recovery in the Postanesthesia Care Unit
Quality of Recovery in the Post-anesthesia Care Unit
This prospective observational study aims to identify the minimal clinically important difference of the QoR-PACU2 questionnaire.
- Trial name
- MiDiQoR (NCT06905353)
- Volunteers
- 188 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Graves' Disease in Remission (Disorder)
Heart Rate Monitoring by Wearable Devices in Graves' Disease
A multi center randomized controlled study including 3 arms (wearable device group, control group 1, control group 2). This study is to investigate clinical feasibility of heart rate monitoring using wearable devices to detect…
- Trial name
- NCT04333342
- Testing
- heart rate monitoring using wearable devices
- Where
- 6 sites in South Korea
- Volunteers
- 180 people
- Sponsor
- Seoul National University Bundang Hospital
Rare Diseases, Thoracic Aortic Aneurysm (TAA)
Fibroblasts and Thoracic Aortic Aneurysms: in Vitro Characterization in With Marfan Syndrome and Genetic Aortic Diseases
The aim of the present study is to characterise the phenotype of fibroblasts and to classify different mechanisms involved in the onset and progression of TAAD in syndromic and non-syndromic subjects in order to evaluate…
- Conditions
- Rare Diseases, Thoracic Aortic Aneurysm (TAA), Marfan Syndrome
- Trial name
- FIBRA (NCT06786754)
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Unprotected Left Main Coronary Artery Disease
Comparison of HYBRID Versus Two-Stent Strategies in Unprotected True Left MAIN Bifurcation
The number of deaths from heart disease is rising globally, particularly in developing countries. This condition involves the narrowing of arteries that supply blood to the heart.
- Trial name
- HYBRID MAIN (NCT07159737)
- Testing
- Two-stent strategy, Hybrid Strategy
- Volunteers
- 800 people
- Sponsor
- Hospital Sultanah Bahiyah
Heart Failure
Management of Acute Heart Failure: Contribution of Ultrasound Daily "in Bed Patient" Adjustment on Therapy With Impact Measure on re Hospital Rate During 30 Days
Our hypothesis: a daily bedside echocardiographic assessment, protocolized, simple and reproducible estimation of filling pressures with an evaluation of mitral inflow and the inferior vena cava, allow a more reliable estimate of…
- Trial name
- JECICA (NCT02892227)
- Testing
- Transmitral flow estimation
- Where
- 2 sites in France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Chest Pain, Anxiety
The Effects of Use of Auditory Stimulation Methods on Cardiac Patients' Clinical Outcomes
This study will be used to compare the effects of two auditory stimulation methods on improving vital signs parameters, reducing the severity of chest pain, and improving the sleep quality of cardiac patients.
- Conditions
- Chest Pain, Anxiety, Sleep
- Trial name
- NCT06670027
- Testing
- Family voice, Nature sound
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Damanhour University
Coronary Artery Disease
Everolimus- Versus Biolimus-Eluting Stents in All-Comers
This study sought to investigate safety and efficacy of biolimus-eluting stents (BES) with biodegradable polymer as compared with everolimus-eluting stents (EES) with durable polymer through 3 years of follow-up.
- Trial name
- EverBio (NCT01472705)
- Where
- Switzerland
- Volunteers
- 814 people
- Sponsor
- University of Freiburg
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