Clinical trials: Coronary Patient
Hypertension, Insulin Resistance
Effects of Pioglitazone in Hypertensive Patients
Insulin resistance is often complicated with hypertension. AGE and inflammation play important roles in insulin resistance. Some studies reported that pioglitazone, insulin sensitizer, is effective for patients with insulin…
- Trial name
- NCT01472497
- Testing
- Pioglitazone
- Where
- Japan
- Volunteers
- 16 people
- Sponsor
- Tottori University Hospital
Angina Pectoris, Metabolic Syndrome X
Rosiglitazone Versus Placebo in Chronic Stable Angina
We wish to see if the drug rosiglitazone, currently used in the treatment of type 2 diabetes, could be used as a new treatment for angina when compared with placebo in overweight subjects who do not have overt diabetes.
- Trial name
- NCT00225355
- Testing
- Rosiglitazone
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Glasgow
Rhythm; Disorder
Audiovisuell Distraction Via 2d Videoglasses During Catheter Ablation Procedures in Cardiac Rhythm Disorders.
In this randomized controlled trial, amount of sedation exposure and patient satisfaction is evaluated in patients undergoing catheter ablation for rhythm disorders via an audiovisual distraction.
- Trial name
- NCT04873076
- Testing
- Audiovisual distraction using 2d video glasses from HappyMed GmbH
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- University Hospital, Essen
Cardiac Surgery in Adult Patient
Randomized Trial of 2% Chlorhexidine-70% Isopropanol vs 5% Povidone Iodine-69% Ethanol for Skin Antisepsis in Reducing Surgical-site Infection After Cardiac Surgery
Despite completion of more than 9 million procedures each year in France, the best antiseptic solution to be used for preparing the skin to reduce risk of surgical site infection (SSI) remains unknown.
- Trial name
- CLEAN2 (NCT03560193)
- Testing
- 2%Chlorhexidine-70%Isopropanol, 5%Povidone Iodine- 69%Ethanol
- Where
- 8 sites in France
- Volunteers
- 3,316 people
- Sponsor
- Poitiers University Hospital
Cardiac Surgery, Cardiopulmonary Bypass
Heparin Based on Ideal Body Weight for Cardiopulmonary Bypass in Obese Patients
The optimal heparin regimen during cardiopulmonary bypass (CPB) has not been well established in obese patients. Results of a preview study show that the standard heparin management based on total body weight in obese patients…
- Conditions
- Cardiac Surgery, Cardiopulmonary Bypass, Obese Patients (BMI ≥ 30 kg/m²)
- Trial name
- HEPOIRINE (NCT02675647)
- Testing
- Heparin, IV route, based on patients body weights (UI/kg), Cardiopulmonary bypass, Protamin administration
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Strength Training Effects, HFrEF - Heart Failure With Reduced Ejection Fraction
Eccentric Muscle Training in Cardiac Rehabilitation
The goal of this interventional study is to assess the training effects in a training schedule in which eccentric overload training and eccentric cycle training are used.
- Trial name
- NCT07636343
- Testing
- eccentric bike training, eccentric overload training, aerobic treadmill training
- Where
- Belgium
- Volunteers
- 3 people
- Sponsor
- University Hospital, Antwerp
Block Complete Heart, Atrial Fibrillation (AF)
Closed-Loop Stimulation in Left Bundle Branch Area Pacing
This prospective, single-center, crossover study evaluated the effects of closed-loop stimulation (CLS) compared with conventional accelerometer-based rate-adaptive pacing (VVIR) in patients with permanent atrial fibrillation…
- Conditions
- Block Complete Heart, Atrial Fibrillation (AF), Chronotropic Incompetence
- Trial name
- NCT07812935
- Testing
- Closed-Loop Stimulation, Accelerometer-Based VVIR Pacing
- Where
- Poland
- Volunteers
- 33 people
- Sponsor
- Bartlomiej Wrobel
Female, Male
Towards a Sex-specific "Female Enhanced Recovery After Cardiac Surgery'' (F-ERAS) Pathway:
The aim of this study is to evaluate the differences between men and women undergoing cardiac surgery. We will look at perioperative factors such as body weight, body surface area, previous medical history, pharmacokinetics…
- Conditions
- Female, Male, Surgery,Cardiac
- Trial name
- F-ERAS (NCT06175650)
- Testing
- Cardiac surgery
- Where
- Netherlands
- Volunteers
- 5,500 people
- Sponsor
- Jennifer Breel
Chagas Disease, Chagas Cardiomyopathy
Cardiac Rehabilitation in Chagas Heart Failure
Due to the lack of information in the literature about the role of cardiac rehabilitation on Chagas heart failure, the aim of the present study was to evaluate the effects of a cardiac exercise program on functional capacity…
- Trial name
- NCT02516293
- Testing
- Exercise, nutritional and pharmaceutical counseling
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Evandro Chagas National Institute of Infectious Disease
Homebased Cardiac Rehabilitation Program After Ischemic Heart Disease
Homebased Monitoring Cardiac Rehabilitation Program
The current state of mobile communication and technology is a tool to support home programs for chronic disease management, useful to facilitate access to these types of programs, because the investigators could obtain telematics…
- Trial name
- NUUBO (NCT02796404)
- Testing
- Homebased cardiac rehabilitation program, Traditional cardiac rehabilitation program
- Where
- 3 sites in Spain
- Volunteers
- 148 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Coronary Artery Disease, Human Immunodeficiency Virus (HIV)
Pericardial Fat and Inflammation in HIV Patients and Controls
The investigators propose to correlate 1) cardiac MRI pericardial adipose volume, 2) the presence of pericardial monocytes and 3) circulating immune biomarkers in persons with and without CHD and HIV infection compared to…
- Trial name
- NCT02399384
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Cincinnati
Intubation Complication
Evaluation of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation Using Conventional Laryngoscope Versus C-MAC Video Laryngoscope in Patients Undergoing Elective Coronary Artery Bypass Grafting (CABG) Surgery
This study is being done to compare hemodynamic response upon endotracheal intubation using either conventional laryngoscopy with Macintosh blade versus C-Mac video laryngoscope in patients undergoing elective coronary artery…
- Trial name
- NCT04433884
- Testing
- Endotracheal intubation using a laryngoscope
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- Aga Khan University
Acute Coronary Syndrome
Long-term Follow-up of Health Related Quality of Life in Patients With Acute Coronary Syndrome
This study is aiming to i)measure longterm health related quality of life (HRQL) outcomes of the EMMACE3 patients hospitalised with acute coronary syndromes (ACS) and evaluate possible associations with their cardiovascular…
- Trial name
- EMMACE-3X (NCT01955525)
- Where
- United Kingdom
- Volunteers
- 3,500 people
- Sponsor
- University of Leeds
Quality of Life
Impact of Perioperative Exenatide Infusion on Quality of Life in Cardiac Surgery Patients
A diminution of quality of life is often reported by patients after coronary artery bypass graft (CABG) surgery. A part of this diminution could be explain by postoperative left ventricular (LV) dysfunction.
- Trial name
- ExeQOL (NCT02432976)
- Testing
- Exenatide, Insulin
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Refractory Angina Pectoris
Extracorporeal Shock Wave Therapy for the Treatment of Ischemic Heart Disease
Low intensity shockwaves have been proven in animal studies to induce local growth of new blood vessels from existing ones. The hypothesis of this study is that shockwave therapy could improve the symptoms of patients with…
- Trial name
- NCT01241968
- Testing
- Cardiac Extracorporeal Shockwave Therapy generator (Cardiospec)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Medispec
Heart Failure
Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure
The study is designed to be a prospective, randomized study is to compare the effectiveness of two standard of care loop diuretics (furosemide versus torsemide) on clinical outcomes among patients currently on a stable dose of…
- Trial name
- TFO (NCT05093621)
- Testing
- Furosemide, Torsemide
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Yale University
Cryptogenic Stroke, Atrial Fibrillation
Incidence and Predictors of Recurrent Stroke in Cryptogenic Stroke Patients With Atrial Fibrillation
Brief Summary: This study aimed to investigate the risk and factors that predict recurrent stroke in patients who initially had a stroke with no clear cause (called cryptogenic stroke) and were later found to have atrial…
- Conditions
- Cryptogenic Stroke, Atrial Fibrillation, Recurrent Ischemic Stroke
- Trial name
- NCT07126184
- Testing
- Extended Cardiac Monitoring
- Where
- Pakistan
- Volunteers
- 109 people
- Sponsor
- Nangarhar University
Aortic Regurgitation
Velocity Vector Imaging in Patients With Moderate-to-Severe Aortic Regurgitation
Velocity Vector Imaging may provide reliable and detailed information on left ventricular segmental function in asymptomatic patients with moderate-to severe AR.
- Trial name
- NCT00624884
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Florence Nightingale Hospital, Istanbul
STEMI - ST Elevation Myocardial Infarction, Reperfusion Injury, Myocardial
Combination With Treg Levels and CMR to Assess the Severity and Prognosis of Reperfusion Injury After PPCI in STEMI Patients
This study aims to determine whether combination with regulatory T cell (Treg) levels and cardiac magnetic resonance imaging (CMR) are predictive of the severity of reperfusion injury following myocardial infarction and the…
- Trial name
- TregCMRRS (NCT03939338)
- Testing
- Treg levels and CMR results
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Beijing Friendship Hospital
Amyloidosis, AL Amyloidosis
BE.Amycon Biobank & Data Registry UZ Leuven
The goal of this study is to collect and store human body material (HBM) of patients with amyloidosis in a biobank "BE.Amycon biobank" for future research and to collect clinical data of patients with amyloidosis in a database…
- Conditions
- Amyloidosis, AL Amyloidosis, Amyloidosis Cardiac
- Trial name
- NCT07172243
- Where
- 2 sites in Belgium
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
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