Clinical trials: Coronary Patient
Pulmonary Hypertension
Ablation of the Pulmonary Artery With High Pulmonary Hypertension During Mitral Valve Surgery
The aim of this prospective randomized study was to evaluate the effectiveness and safety of the original ablation procedures ganglion plexus pulmonary artery with simultaneous correction of valvular heart disease, complicated by…
- Trial name
- NCT02374229
- Testing
- Surgical ablation of ganglion plexus pulmonary artery., mitral valve surgery
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Heart Disease, Myocardial Infarction
Prospective Coronary Heart Disease Cohort
To evaluate the biomarkers for the prognosis of coronary heart disease, patients with coronary heart disease will be recruited and followed up for at least 2 years.
- Trial name
- NCT05699629
- Where
- China
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- Shandong First Medical University
Congestive Heart Failure
THalidomide on Left ventricUlar Morphology aND Function in congEstive heaRt Failure
Several studies have shown that inflammation and matrix degradation have pathogenic effects on the myocardium by influencing heart contractility, inducing hypertrophy, degrading the matrix, or enhancing fibrosis, thus…
- Trial name
- THUNDER (NCT01640639)
- Testing
- Thalidomide
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
Ventilator Weaning, Airway Extubation
Can a Pain Monitor Predict When Postoperative Intensive Care Unit Patients Are Ready to Breathe on Their Own? A Pilot Study
The goal of this observational study is to learn if a chest monitor that tracks heart rhythm can help predict whether adults on a breathing machine after surgery will be able to breathe on their own once the breathing tube is…
- Conditions
- Ventilator Weaning, Airway Extubation, Respiration, Artificial
- Trial name
- NCT07771101
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Diabetes Mellitus, Coronary Disease
Empagliflozin Versus Sitagliptin Therapy for Improvement of Myocardial Perfusion Reserve in Diabetic Patients With Coronary Artery Disease
This trial evaluates the effects of Empagliflozin versus Sitagliptin, in addition to standard of care, on global myocardial perfusion reserve using dynamic single-photon emission computed tomography (SPECT) images.
- Trial name
- ELITE (NCT03208465)
- Testing
- Empagliflozin, Sitagliptin
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- CHEOL WHAN LEE, M.D., Ph.D
Cardiogenic Shock, Extracorporeal Membrane Oxygenation
Effect of Reduced Vasopressors on Mortality in ECMO-supported Cardiogenic Shock Patients
The goal of this observational study is to learn about the association between vasopressor exposure levels and outcomes in adults with cardiogenic shock receiving VA-ECMO.
- Conditions
- Cardiogenic Shock, Extracorporeal Membrane Oxygenation, Vasopressors, Hemodynamic Management
- Trial name
- VREM-CS (NCT06862700)
- Testing
- Vasopressor Exposure Levels
- Where
- China
- Volunteers
- 534 people
- Sponsor
- Xiaotong Hou
Atrial Fibrillation (AF), Obesity & Overweight
Exercise and Dietary Lifestyle Intervention on Reducing Atrial Fibrillation Burden, Cardiac and Body Fat Mass.
Atrial fibrillation (AF) is the most common cardiac arrhythmia and is strongly associated with obesity and excess body fat. Lifestyle interventions, including exercise and dietary modification, may reduce AF burden, but long-term…
- Trial name
- MOVE-AF (NCT07430007)
- Testing
- Tailored Exercise and Dietary Lifestyle Program, Usual Clinical Care
- Where
- 4 sites in Finland
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Type 2 Diabetes Mellitus
Vascular Function and Biomarker Assessments in Healthy Volunteers and in Patients With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate the vascular function and biomarkers in healthy volunteers and type 2 diabetic patients.
- Trial name
- NCT04744636
- Testing
- Other
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institut de Recherches Internationales Servier
Myocardial Infarction
Study on the Efficacy and Mechanism of Cardiac Rehabilitation for Stem Cell Mobilization and Heart Failure Improvement
One emerging concept is that some form of injury or inflammation is a prerequisite for the success of circulating-cell participation in differentiated tissue structure and function.
- Trial name
- NCT00154466
- Testing
- cardiac rehabilitation
- Where
- Taiwan
- Volunteers
- 58 people
- Sponsor
- National Taiwan University Hospital
Primary Amyloidosis of Light Chain Type
High Cut-off Hemodialysis in Patients With Advanced Cardiac AL Amyloidosis and End Stage Renal Disease
The aim of the study is to assess survival of patients with advanced cardiac AL amyloidosis treated with high cut-off hemodialysis (HCO-HD) combined with chemotherapy.
- Trial name
- DIACAL (NCT01531751)
- Testing
- High Cut-off Hemodialysis, Chemotherapy
- Where
- Italy
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention
The EPIVER Randomized Controlled Trial
The trial aims to estimate the efficacy and safety of the intracoronary administration of adrenalin, verapamil, as well as their combination compared to standard treatment in patients with STEMI and refractory coronary no-reflow…
- Conditions
- ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention, No-Reflow Phenomenon
- Trial name
- EPIVER (NCT04573751)
- Testing
- Standard therapy, Epinephrine, Verapamil
- Where
- Russia
- Volunteers
- 104 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Diabetes
Effect of Compound Danshen Dripping Pills on Diabetic Patients With Coronary Microcirculation Disturbance
Most patients with diabetes complicated with microvascular circulation disorder have normal coronary angiography but still suffer from chest tightness, chest pain and so on.
- Trial name
- NCT05295329
- Testing
- Compound Danshen Dropping Pills
- Where
- 7 sites in China
- Volunteers
- 120 people
- Sponsor
- Ruijin Hospital
Cardiac Surgery, Insulin Resistance
Impact of Preoperative Oral Carbohydrate Loading on Insulin Resistance in Adult Cardiac Surgery Patients
The goal of this clinical trial is to investigate the effect of preoperative oral carbohydrate on insulin resistance in adult cardiac surgery patients with a cardiopulmonary bypass machine.
- Trial name
- NCT07212153
- Testing
- Oral Carbohydrate Drink (Maltodextrin)
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Rifdhani Fakhrudin Nur
Stable Coronary Artery Disease
Impact of Intensive Exercise Training on Coronary Collateral Circulation in Patients With Stable CAD
Exercise training in patients with coronary artery disease is able to correct several risk factors. Furthermore endothelial function can be improved.
- Trial name
- NCT01209637
- Testing
- exercise training, Intensive exercise training
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Leipzig
Heart Failure
A Study on Remote Health Support for Patients With Heart Failure.
This multicenter prospective observational feasibility study evaluates the implementation of the RAPHAEL model, a remote monitoring palliative care approach for patients with heart failure.
- Trial name
- RAPHAEL (NCT07440472)
- Where
- 9 sites in Germany, Italy and 7 more
- Volunteers
- 90 people
- Sponsor
- Universitat Internacional de Catalunya
Type 2 Diabetes, Coronary Heart Disease
Trial on Safety & Performance of TAXUS Element vs. XIENCE Prime Stent in Treatment of Coronary Lesion in Diabetics
The TUXEDO-India is a prospective, single blind, multi-center randomized clinical trial to assess the TAXUS Element™ in a consecutive population of diabetic patients with coronary artery disease undergoing coronary…
- Trial name
- Tuxedo (NCT03125772)
- Testing
- TAXUS Element™ Paclitaxel-Eluting Stent System, Xience PRIME Everolimus-Eluting Stent System
- Where
- India
- Volunteers
- 1,830 people
- Sponsor
- Fortis Escorts Heart Institute
Heart Failure With Preserved Ejection Fraction (HFpEF)
An Open-label Extension Study Evaluating Safety and Tolerability of LCZ696 in Subjects Who Completed PARAGON-HF in Japan.
This study evaluated the safety and tolerability of LCZ696 treatment in Japanese heart failure patients (NYHA Class II-IV) with preserved ejection fraction after CLCZ696D2301 (PARAGON-HF).
- Trial name
- NCT03909295
- Testing
- LCZ696
- Where
- 17 sites in Japan
- Volunteers
- 52 people
- Sponsor
- Novartis Pharmaceuticals
Stable Angina (SA), Unstable Angina (UA)
Breaking Fasts Ahead of Cardiac Caths
The goal of this clinical trial is to find out whether fasting is necessary before urgent inpatient cardiac catheterizations. For patients presenting with urgent heart-related pain or even mild heart attacks, researchers want to…
- Conditions
- Stable Angina (SA), Unstable Angina (UA), NSTEMI - Non-ST Segment Elevation MI
- Trial name
- BACON-RCT (NCT06996639)
- Testing
- Non-Fasting, Fasting
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of South Florida
Heart Failure
Clinical Efficacy of Remote Monitoring in the Management of Heart Failure
This is a clinical trial to evaluate the clinical benefit of remote monitoring in patients with heart failure having an ICD-CRT implanted.
- Trial name
- EFFECT (NCT01723865)
- Where
- 16 sites in Italy
- Volunteers
- 988 people
- Sponsor
- Effect Group, Italy
Acute Myocardial Infarction
A Study of INO-1001, an Intravenous PARP (Poly [ADP Ribose] Polymerase) Inhibitor in Acute Heart Attack Patients Undergoing Primary Percutaneous Coronary Intervention
The primary purpose of this study is to assess the safety of INO-1001 in subjects who have experienced a heart attack and are to be treated with coronary angioplasty.
- Trial name
- NCT00271765
- Testing
- INO-1001
- Where
- 16 sites in United States, Israel
- Volunteers
- 40 people
- Sponsor
- Inotek Pharmaceuticals Corporation
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