Clinical trials: Coronary Patient
Atrial Fibrillation
Atrial Fibrillation: Canadian Atrial Fibrillation Evaluation (CAFE) Study -
To evaluate whether atrial fibrillation (AF) therapies in Guidant Pulsar Max II or Insignia Plus DR have an effect on the occurance of AF in patients with no prior history of AF
- Trial name
- CAFE (NCT00848445)
- Testing
- Guidant Pulsar Max II or Insignia Plus DR, Atrial pacing preference turned on or off
- Volunteers
- 270 people
- Sponsor
- Boston Scientific Corporation
Arrhythmogenic Right Ventricular Cardiomyopathy, FAPI PET
FAPI PET/CT Imaging in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (FAPI-ARVC))
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease associated with fibrofatty myocardial replacement, ventricular arrhythmias, and an increased risk of sudden cardiac death.
- Conditions
- Arrhythmogenic Right Ventricular Cardiomyopathy, FAPI PET, Cardiac Magnetic Resonance Imaging
- Trial name
- FAPI-ARVC (NCT07563660)
- Testing
- 68Ga-DOTA-SA-FAPI PET/CT
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Istanbul University - Cerrahpasa
Atrial Fibrillation
Atrial Fibrillation Characterization on Paroxysmal and Persistent Patients
Background and Hypothesis: Atrial Fibrillation (AF) treatment strategies have limitations. The efficacy of the procedure depends in several factors such as age, AF duration, atrial diameter and atrial electrophysiological…
- Trial name
- PAPER-AF (NCT05343923)
- Where
- Spain
- Volunteers
- 55 people
- Sponsor
- Felipe Atienza
Chronic Heart Failure, Iron Deficiency
Intravenous Iron Treatment in Patients With Heart Failure and Iron Deficiency: IRONMAN
This study will address whether the additional use of Intravenous (IV) iron on top of standard care will improve the outlook for patients with heart failure and iron deficiency.
- Conditions
- Chronic Heart Failure, Iron Deficiency, Left Ventricular Systolic Dysfunction
- Trial name
- IRONMAN (NCT02642562)
- Testing
- Ferric Derisomaltose
- Where
- 72 sites in United Kingdom
- Volunteers
- 1,160 people
- Sponsor
- University of Glasgow
Atherosclerotic Vascular Disease
Colchicine in Vascular Inflammation Assessed With PET Imaging
The purpose of this trial is to assess the effects of colchicine on vascular inflammation measured by (FDG)-PET imaging in patients with atherosclerotic vascular disease.
- Trial name
- COLPET (NCT02162303)
- Testing
- Colchicine
- Where
- Canada
- Volunteers
- 106 people
- Sponsor
- Montreal Heart Institute
Pulmonary Disease, Chronic Obstructive
Changes in Blood Gases, Disturbance of Breath During Sleep and Cardiovascular Co-morbidity in COPD Patients
Respiration failure type 2 is loss of the lungs ability to take up oxygen (O2) and get rid of carbon dioxide (CO2). The diagnosis is based on blood gas measurement of pressures of O2 and CO2.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Hypercapnia, Hypoxemia
- Trial name
- NCT00888342
- Testing
- supplementary oxygen, zopiclone, alcohol
- Where
- 2 sites in Norway
- Volunteers
- 150 people
- Sponsor
- LHL Helse
Chronic Heart Failure, Coronary Disease
Role of Endothelial Function, Muscular Fitness and Metabolism in Functional Activity in Patients With Chronic Heart Failure (CHF)
Shortness of breath, fatigue, and exercise intolerance are clinical symptoms of chronic heart failure (CHF). Recent studies suggested that peripheral impairment was the major cause of clinical symptoms, and mechanism may be…
- Conditions
- Chronic Heart Failure, Coronary Disease, Dilated Cardiomyopathy
- Trial name
- NCT01139086
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Heart Failure
Evaluation of the Program to Help Return Home Patients Hospitalized for Heart Failure, From Paris Saint-Joseph Hospital
The prevalence of heart failure is very high worldwide is between 1 and 2% in developed countries. The French Federation of Cardiology estimates that a million people are affected in France.
- Trial name
- PRADO_IC2 (NCT04613973)
- Where
- France
- Volunteers
- 633 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Hypoplastic Left Heart Syndrome (HLHS), Aortic Arch Hypoplasia
Seeking for Perfected Aortic Arch Reconstruction Using a Graphically Designed Patient-specific Surgical Patch
Vascular Reconstruction is one of the most challenging areas of surgery, the surgeon has to create a completely watertight reconstruction without any narrowing or deformity that will restore normal flow characteristics, even at…
- Trial name
- NCT06853054
- Testing
- Personalized patch template
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- The Hospital for Sick Children
End Stage Renal Disease
Monitoring in Dialysis -- a Prospective, Multi-center, Single-arm, Non-randomized, Observational Study in Patients Who Are Undergoing Hemodialysis.
The primary objective of this study is to estimate the proportion of hemodialysis patients experiencing clinically significant cardiac arrhythmias over a 6-month period using continuous cardiac monitoring with an implanted…
- Trial name
- MiD (NCT01779856)
- Testing
- REVEAL Insertable Cardiac Monitor (ICM)
- Where
- 10 sites in United States, India
- Volunteers
- 81 people
- Sponsor
- Medtronic Corporate Technologies and New Ventures
STEMI, Cardiovascular Disease
Vascular Healing After Implantation of FANTOM Bioresorbable Scaffold in STEMI: A FANTOM STEMI Study
The study will assess the safety and performance of the Fantom sirolimus eluting bioresorbable vascular scaffold (BVS) in the acute setting of myocardial infarction with unstable lesions and thrombogenic milieu.This is a…
- Conditions
- STEMI, Cardiovascular Disease, Bioresorbable Scaffold
- Trial name
- FANTOM STEMI (NCT03785431)
- Testing
- PCI with Phantom Bioresorbable Scaffold
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- Medical University of Warsaw
Inherited Cardiac Arrhythmias, Long QT Syndrome
Long Term Monitoring for Risk of Sudden Death
Risk prediction in in inherited heart rhythm conditions that may cause sudden cardiac arrest or death is difficult. Sometimes the risks may be low but the loss of life in an otherwise healthy young individual is catastrophic.
- Conditions
- Inherited Cardiac Arrhythmias, Long QT Syndrome, Arrhythmogenic Right Ventricular Cardiomyopathy, Brugada Syndrome
- Trial name
- NCT04124237
- Where
- Canada
- Volunteers
- 1,051 people
- Sponsor
- University of British Columbia
Paroxysmal Atrial Fibrillation
SINGLE SHOT CHAMPION
Pulmonary vein isolation (PVI) is an effective treatment for atrial fibrillation (AF). Currently, Medtronic Arctic Front Cryoballoon is the most frequently used single shot technology and hence is the benchmark for upcoming…
- Trial name
- NCT05534581
- Testing
- PVI using the Arctic Front Cryoballoon (Medtronic), PVI using FARAPULSE Pulsed Field Ablation (Boston Scientific)
- Where
- 2 sites in Switzerland
- Volunteers
- 210 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Heart Diseases
The Precision of Pulmonary Artery Cardiac Output-measurements in Spontaneously Breathing Patients
The intention of this study is to determine whether the precision of the measure of cardiac output can be optimized by conducting the measurement while the participant is instructed to exhale slowly.
- Trial name
- TEMP2 (NCT01944254)
- Testing
- Cardiac output measurement at random to respiration, Cardiac output measurement synchronised at start of expiration, Cardiac output measurement timed to instructed exhalation
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Norwegian University of Science and Technology
Diabetes Mellitus
Comparison of Coronary Xience V and the Cypher Select+ Stents in Diabetic Patients
In stent neointimal hyperplasia may be less in the Cypher select plus stent compared to the Xience V stent in diabetic patients.
- Trial name
- DIABEDES IV (NCT00552994)
- Testing
- Cypher Select plus, Xience V stent
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Odense University Hospital
Friedreich Ataxia
Coronary Artery Disease in Patients With Friedreich's Ataxia
Friedreich's ataxia is a debilitating, inherited disease cause by mutations in a protein called frataxin (FXN). FXN is one of several proteins that controls the production of iron-sulfur clusters, molecules that are essential for…
- Trial name
- NCT04649866
- Testing
- plethysmography
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Pittsburgh
Left Ventricular Dysfunction, Coronary Artery Bypass Surgery
Laboratory Outcome Predictors in Coronary Surgery
Evaluate less employed markers of tissue hypoperfusion as venoarterial carbon dioxide partial pressure difference (ΔPCO2) and estimated respiratory quotient (eRQ) combined to other classically studied markers as predictive…
- Conditions
- Left Ventricular Dysfunction, Coronary Artery Bypass Surgery, Tissue Hypoperfusion
- Trial name
- NCT01178866
- Where
- Brazil
- Volunteers
- 87 people
- Sponsor
- University of Sao Paulo
Atrial Fibrillation
Eliminate Thromboembolism: Improving Anticoagulation in Non-valvular Atrial Fibrillation Patients
ELITE (Eliminate Thromboembolism: Improving Anticoagulation in Non-valvular Atrial Fibrillation Patients) is a two year research project to assess warfarin management issues faced by atrial fibrillation (AF) patients in…
- Trial name
- ELITE (NCT02461602)
- Where
- 21 sites in United States
- Volunteers
- 251 people
- Sponsor
- Duke University
Heart Failure
Characterizing Guideline Adoption and Treatment Quality in Clinical Routine of German HFrEF Care
This was a multicenter, non-randomized, non-interventional cohort study with prospective and retrospective collection of primary data on heart failure with reduced ejection fraction (HFrEF) patient treatment and care following a…
- Trial name
- CONNECT (NCT06004453)
- Testing
- Heart Failure medications
- Where
- 94 sites in Germany
- Volunteers
- 899 people
- Sponsor
- Novartis Pharmaceuticals
Perioperative/Postoperative Complications, Morality
Estimated Oxygen Extraction Versus Dynamic Parameters for Perioperative Hemodynamic Optimization
The aim of the study is to evaluate the complications rate of high risk patients undergoing non-cardiac surgery that receive two different protocols of hemodynamic optimization.
- Trial name
- NCT04053595
- Testing
- Dynamic parameters of fluid responsiveness protocol, Estimated oxygen extraction protocol
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Università Politecnica delle Marche
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