Clinical trials: Coronary Patient
Diastolic Dysfunction
Perioperative Measurements of Diastolic Function in Cardiac Surgery
This observational clinical trial will investigate the following perioperative indices relating to cardiac surgery: 1. The significance of measurements involving left heart relaxation (LV diastolic function) and its relation to…
- Trial name
- NCT02285309
- Testing
- Cardiac Surgery and enoximone
- Volunteers
- 100 people
- Sponsor
- University College, London
Counterpulsation, Angina Pectoris
Effectiveness of ECP Therapy in Stable Angina Pectoris Patients
External Counterpulsation (ECP) is a non-invasive therapy using pressured cuff that is performed on patients with refractory stable angina pectoris to relieve symptoms and increase quality of life.
- Trial name
- NCT04873687
- Testing
- External Counter Pulsation (ECP) therapy
- Where
- Indonesia
- Volunteers
- 84 people
- Sponsor
- Universitas Padjadjaran
Atrial Fibrillation, Anticoagulants and Bleeding Disorders
Safety and Efficacy of Edoxaban in Thoracoscopic Ablation
The aim of this study is to compare the safety and efficacy of edoxaban and warfarin for prevention of stroke during a 6-month follow up after total thoracoscopic ablation.
- Trial name
- NCT04121767
- Testing
- Edoxaban, Warfarin
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Heart Diseases, Left Ventricular Dysfunction
InterventiOn of Biventricular Pacemaker Function on ventrIcular Function Among Patients With LVAD's
The primary reason the investigators are doing this study are to understand how the right side of the heart functions in heart failure patients with left ventricular assist devices (LVADs, or "mechanical hearts").
- Trial name
- ROBIN (NCT03232736)
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Coronary Heart Disease, Atherosclerosis
Fluvastatin AmelIorates aTHerosclerosis Study
The study is designed to assess the effect of statin on atherosclesrosis progression as well as to explore its potential mechanism besides lipid modifying , such as effect on inflammation and vascular calcification.
- Trial name
- FAITH (NCT01681199)
- Testing
- Fluvastatin extended release tablet
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Beijing Anzhen Hospital
Heart Failure
Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure
The study is designed to be a prospective, randomized study is to compare the effectiveness of two standard of care loop diuretics (furosemide versus torsemide) on clinical outcomes among patients currently on a stable dose of…
- Trial name
- TFO (NCT05093621)
- Testing
- Furosemide, Torsemide
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Yale University
Psoriasis, Vascular Inflammation
Trial on the Effect of Adalimumab on Vascular Inflammation in Patients With Psoriasis
This study is a double-blinded randomized multicenter placebo controlled trial to determine the effect of adalimumab on vascular inflammation (ascending aorta and carotides) in patients with moderate to severe psoriasis.
- Conditions
- Psoriasis, Vascular Inflammation, Coronary Atherosclerosis
- Trial name
- NCT01722214
- Testing
- Adalimumab
- Where
- 5 sites in Canada
- Volunteers
- 107 people
- Sponsor
- Innovaderm Research Inc.
Heart Failure
Corheart 6 LVAS Long-term Follow-up Study
The purpose of this clinical study is to explore the long-term efficacy and safety of the Corheart 6 Left Ventricular Assist System (LVAS) as a treatment for patients with advanced heart failure.
- Trial name
- NCT06267612
- Testing
- Corheart 6 Left Ventricular Assist System
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Heart Patients After ICD Implantation
Rehabilitation, Quality of Life, and Exercise Tolerance in Patients With an ICD
RELAX-ICD Trial/Research Study; Quality of Life/Protocol No.P-KARE-01: A 3-month outpatient rehabilitation therapy and psychological counselling including informative talks with conventional therapy, by a cardiologist or general…
- Trial name
- NCT00346112
- Testing
- psycho-educational
- Where
- Switzerland
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Heart Failure, Decompensated Heart Failure
Use of Point-of-Care Ultrasound (POCUS) to Reduce Hospital Length of Stay in Patients With Heart Failure ( POCUSHF )
This study will evaluate whether using bedside ultrasound (also called Point-of-Care Ultrasound or POCUS) can help improve the care of hospitalized patients with decompensated heart failure.
- Conditions
- Heart Failure, Decompensated Heart Failure, Hospital Length of Stay
- Trial name
- POCUSHF (NCT06965712)
- Testing
- Point-of-Care Ultrasound (POCUS)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Florida International University
COVID-19 Pandemic
The Combined Usage of Clinical Physical Finding in Management of COVID 19 Patients
Physiological indicators such as blood pressure, heart rate, respiratory rate, and consciousness status of COVID-19 patients are used to apply the START (simple triage and rapid treatment, START), Modified Early Warning Score…
- Trial name
- NCT06528119
- Testing
- COVID 19 pandemic
- Where
- Taiwan
- Volunteers
- 10,000 people
- Sponsor
- St. Martin De Porress Hospital
Simulation Training, Anticoagulant Drugs
E-learning to Improve Oral Anticoagulant Use in Hospitalized Older People With AF
Atrial Fibrillation (AF) is the most common cardiac arrhythmia and the main cause of cardioembolic stroke. Oral Anticoagulation (OAC) has been shown to significantly prevent AF-related thromboembolism, however, despite convincing…
- Conditions
- Simulation Training, Anticoagulant Drugs, Elderly, Atrial Fibrillation
- Trial name
- SIM-AF (NCT03188211)
- Testing
- E-learning educational program, Control
- Where
- 20 sites in Italy
- Volunteers
- 247 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Clinical Study
Chronoprognosis of Myocardial Infarction in Patients With Type 2 Diabetes Mellitus
Purpose: To develop a mathematical model for the occurrence of MI in patients with T2D by studying the relationship between the internal personalized biorhythms of the patients and the external transit rhythms of space objects…
- Trial name
- NCT05645419
- Testing
- personalized chronoprevention
- Where
- Kazakhstan
- Volunteers
- 60 people
- Sponsor
- University Medical Center, Kazakhstan
Percutaneous Coronary Intervention
Randomized Controlled Trials of Electro-acupuncture Effects on Perioperative Anxiety in Patients Treated With PCI
Randomized Controlled Trials of Electro-acupuncture Effects on Perioperative Anxiety in Patients Treated with PCI
- Trial name
- NCT03789344
- Testing
- acupuncture, Psychotherapy, blank control
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Huan Wang, MD
Post-Sternotomy Deep Sternal Wound Infection
Vancomycin and Negative Pressure Therapy for Post-sternotomy Deep Sternal Wound Infection
Only a limited number of studies have been published that monitored the penetration of antibiotics from blood into exudate in patients treated with negative pressure wound therapy (NPWT), and that evaluated the adequacy of…
- Trial name
- NCT06506032
- Testing
- Intravenous Vancomycin administration, Standard postoperative therapy
- Where
- 5 sites in Czechia
- Volunteers
- 10 people
- Sponsor
- University Hospital Ostrava
Heart Failure, Prefrail Elderly
High-technology TeleRehabilitation for the Treatment of the FRAgile Patient
The aim of this randomized controlled clinical trial is to evaluate the efficacy of an 8-week sensorimotor and cognitive telerehabilitation program in frail and pre-frail older adults with stable chronic heart failure.
- Conditions
- Heart Failure, Prefrail Elderly, Frail Elderly Syndrome
- Trial name
- TeleRiab4Fra (NCT07561021)
- Testing
- Telerehabilitation, Caregiver-Supervised Home Exercise Program
- Volunteers
- 70 people
- Sponsor
- University of Salerno
Healthy Participants
The Influence of Doctor-patient Communication on Treatment Expectation, Placebo and Nocebo Response
The purpose of this study is to determine whether a patient-centered compared to doctor-centered communication style of a physician influences the treatment expectation and the placebo and nocebo response in healthy individuals.
- Trial name
- SENSE (NCT03949816)
- Testing
- medical consultation: different doctor-patient-centered style of communication, information letter / no medical consultation
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Coronary Artery Disease
Blood Flow Reserve: Effects After Training With Heavy Inspiratory Exercises
The goal of this single-site, parallel-group, double-blind, sham-controlled randomized control trial is to examine the effect of high-intensity inspiratory muscle strength training (IMST) on coronary blood flow assessed using…
- Trial name
- BREATHE (NCT05632614)
- Testing
- High-intensity IMST, Low-intensity IMST
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Acute Coronary Syndrome
Coronary Flow Reserve in Patients With Bio-active Stent or Everolimus-eluting Stent Implanted in Acute Coronary Syndrome
The aim of the trial is to assess coronary artery reactivity using adenosine-induced coronary flow reserve (CFR) by transthoracic echocardiography in patients with Bio-active stent (BAS) and Everolimus-eluting stent (EES) distal…
- Trial name
- BASE-CFR (NCT01080872)
- Testing
- CFR
- Where
- 2 sites in Finland
- Volunteers
- 40 people
- Sponsor
- The Hospital District of Satakunta
Atrial Fibrillation, Type 2 Diabetes
The Effect of High-Intensity Interval Training on Glucose Variability and Atrial Fibrillation Symptoms
The incidence of atrial fibrillation (AF), the most common heart rhythm disorder, is increasing. The symptoms of AF include: unpleasant heartbeats; difficulty breathing; tiredness; dizziness; and, reduced exercise capacity.
- Trial name
- Glucose-AF (NCT04190212)
- Testing
- High-intensity interval training + standard care
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Ottawa Heart Institute Research Corporation
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