Clinical trials: Coronary Revascularization
Erectile Dysfunction, Coronary Artery Disease
Erectile and Ejaculatory Function Following Coronary Revascularization
This observational, cross-sectional study aims to compare erectile and ejaculatory function between men with a history of coronary revascularization and men without known coronary artery disease.
- Conditions
- Erectile Dysfunction, Coronary Artery Disease, Ejaculation Disorders
- Trial name
- NCT07878260
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Coronary Artery Disease (CAD), Bypass, Cardiopulmonary
Multivessel Minimally Invasive Coronary Bypass Grafting as HYBRID Revascularization Versus Conventional Off-pump Coronary Artery Bypass Grafting
The MICRA-HYBRID trial is a prospective, multicenter, randomized controlled study comparing multivessel hybrid coronary revascularization (HCR) as minimally invasive arterial bypass grafting to left-sided coronary targets (LAD…
- Conditions
- Coronary Artery Disease (CAD), Bypass, Cardiopulmonary, Minimally Invasive Coronary Revascularization Surgery, Off-pump Coronary Artery Bypass
- Trial name
- MICRA-HYBRID (NCT07314138)
- Testing
- Multivessel Hybrid Coronary Revascularization, Off-pump coronary arterial bypass grafting (OPCAB)
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
MACE, Cardiac Death
Real-World Cohort Study of Cardiopulmonary Function in Chinese Patients With Cardiovascular Disease: CPET Evaluation and Five-Year Prognostic Follow-Up Based on a Multicenter Structured Data Platform
The goal of this observational study is to observe the characteristics of cardiopulmonary exercise testing (CPET) parameters in patients across different cardiovascular diseases and to evaluate the predictive value of…
- Conditions
- MACE, Cardiac Death, Unplanned Repeat Revascularization, Cardiac Rehospitalization
- Trial name
- China-CPET (NCT07130968)
- Where
- China
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Coronary Artery Disease
Eliminate Coronary Artery Disease
The purpose of this study is to determine whether pharmacologic lowering of low density lipoprotein cholesterol (LDL), initiated in healthy young to middle aged adults can eliminate or markedly reduce the composite endpoint of…
- Trial name
- ECAD (NCT02245087)
- Testing
- Atorvastatin
- Where
- 3 sites in Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Appropriate Use Criteria, Coronary Revascularization
Validation of Chinese Version Appropriate Use Criteria for Coronary Revascularization
Coronary revascularization (CR) is increasing rapidly in China and varies significantly in proportion ( PCI:CABG=15:1). Few studies assess the appropriateness of CR in China.
- Trial name
- NCT02880605
- Where
- China
- Volunteers
- 11,235 people, healthy volunteers welcome
- Sponsor
- China National Center for Cardiovascular Diseases
Ischemic Heart Disease
Oral Glutamine in Cardiopulmonary Bypass
Introduction: Glutamine (GLN) is the most abundant free amino acid in the body. It modulates immune cell function and is an important energy substrate for most cells (especially for enterocytes and lymphocytes) in critical…
- Trial name
- NCT02491931
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Coronary Artery Disease, Angina Pectoris
Change in Exercise Capacity as Measured by Peak Oxygen Uptake After CTO PCI
The purpose of this project is to objectively assess the change (improvement) in exercise capacity in patients undergoing routine percutaneous coronary intervention (PCI) for chronic total occlusion (CTO)
- Trial name
- EXERTION (NCT02499666)
- Testing
- Percutaneous Coronary Intervention, Coronary stent, Clopidogrel
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Myocardial Infarction
Complete Lesion Versus Culprit Lesion Revascularization
To investigate the clinical outcomes of acute myocardial infarction (AMI) patients with multivessel disease undergoing percutaneous coronary intervention (PCI) either in infarct-related artery only or in multivessel in Drug…
- Trial name
- COCUA (NCT01180218)
- Testing
- complete revascularization, Culprit revasularization
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Diabetes Mellitus, Insulin Resistance
Diabetes Genome Project: A Prospective Registry to Identify Genetic Variation Among Diabetic Patients
Previous scientific research has found multiple genes that affect the risk for developing heart disease or complications during the treatment of heart disease.
- Conditions
- Diabetes Mellitus, Insulin Resistance, Atherosclerosis
- Trial name
- DGP (NCT00428961)
- Where
- United States
- Volunteers
- 1,607 people, healthy volunteers welcome
- Sponsor
- Saint Luke's Health System
Coronary Artery Disease
Clinical and Angiographic Outcomes of Post-drug-coated Balloon Angioplasty in Native Coronary Lesions
The progression of cardiac revascularization techniques, starting with standard balloon angioplasty (POBA) and progressing to the creation of drug-coated balloons (DCB) and drug-eluting stents (DES).
- Trial name
- NCT06340373
- Testing
- DCB Angioplasty
- Where
- Bangladesh
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiovascular Diseases, Bangladesh
Cardiac Infarct, Cardiac Event
Feasibility of the "Heart-track" Rehabilitative Device Prototype
Abstract Title: "Heart-track" cardiac rehabilitation device prototype designed for exercise training post coronary revascularisation: A usability study Background: Percutaneous Coronary Intervention (PCI) is a common surgical…
- Trial name
- NCT04059627
- Testing
- Heart Track
- Where
- Singapore
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Coronary Artery Disease
Clinical Validation of PROPECG-TMT
This clinical validation evaluates the performances of physicians with and without learning with PROPECG-TMT assistance for screening coronary artery revascularization on TMT-ECG.
- Trial name
- NCT06624852
- Testing
- Screening for coronary artery revascularization based on TMT-ECG
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI), Dual Anti-platelet Therapy
Aspirin-Free Strategy After 3-6 Month Dual Antiplatelet Therapy in Acute Coronary Syndrome
This randomized controlled trial aims to evaluate the safety and efficacy of an aspirin-free strategy after 3-6 months of dual antiplatelet therapy (DAPT) in patients with acute coronary syndrome (ACS) who have undergone complete…
- Trial name
- NCT07736196
- Testing
- Aspirin-Free Strategy, Dual Antiplatelet Therapy
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Assiut University
Myocardial Infarction
Venous Function in Cardiovascular Disease Patients
The primary aim is to determine the acute effect of two different training interventions on venous plasticity in patients with myocardial infarction (MI), revascularization or coronary artery graft surgery compared to age-matched…
- Trial name
- NCT01474408
- Testing
- interval training day 1, Moderate exercise day 2, Control day 3
- Where
- Norway
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Myocardial Infarction, Coronary Revascularization
Transfusion Trigger After Operations in High Cardiac Risk Patients
The goal of the proposed study is to determine whether a liberal transfusion strategy (transfusion trigger at Hb < 10 gm/dl) in Veterans at high cardiac risk who undergo major open vascular and general surgery operations is…
- Conditions
- Myocardial Infarction, Coronary Revascularization, Acute Renal Failure
- Trial name
- TOP (NCT03229941)
- Testing
- Blood Transfusion
- Where
- 16 sites in United States
- Volunteers
- 1,424 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases
GeneBank at the Cleveland Clinic: Molecular Determinants of Coronary Artery Disease
This proposal delineates a research plan to collect blood from patients undergoing heart catheterization or who have had a heart catheterization within one year and are coming in for outpatient appointments, or who have scheduled…
- Trial name
- GATC (NCT00590200)
- Volunteers
- 9,880 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Myocardial Ischemia, Heart Failure
sST2 Biomarker Level in Acute/Chronic Coronary Syndrome After Revascularization
The role of soluble circulating suppression of tumorigenicity 2 biomarker (sST2) in the ischemic heart disease patient is a debatable point.
- Conditions
- Myocardial Ischemia, Heart Failure, Coronary Intervention
- Trial name
- ST2 (NCT05686057)
- Testing
- percutanous coronary angiography with stenting
- Where
- 2 sites in Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Myocardial Infarction, Ischemic Stroke
Emulation of the Moderate Alcohol and Cardiovascular Health Trial (MACH15)
The aim of this study is to assess how long-term alcohol consumption influences health risks by emulating the Moderate Alcohol and Cardiovascular Health Trial (MACH15).
- Conditions
- Myocardial Infarction, Ischemic Stroke, Angina Pectoris, Coronary Revascularization
- Trial name
- NCT06583161
- Testing
- Moderate drinking, Quitting, Social drinking
- Volunteers
- 503,325 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Primary Percutaneous Coronary Intervention
Influence Of Incomplete Revascularization on Long-Term Outcomes After Primary Percutaneous Coronary Intervention (PPCI)
evaluate the influence of incomplete revascularization during the index hospitalization on in-hospital and long-term outcomes in STEMI patients undergoing PPCI in Assiut University heart hospital.
- Trial name
- NCT04332250
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Amany Edward Ramzy