Clinical trials: Coronary Slow Flow
Coronary Slow Flow
Prediction Value of Ecg on Coronary Slow-flow
The investigators aimed to investigate the vessel heterogeneity of Thrombolysis in Myocardial Infarction frame count (TFC) in the three coronary arteries, and its relation to P-wave dispersion, in patients with coronary slow flow…
- Trial name
- PECS (NCT02650557)
- Testing
- angiography
- Where
- China
- Volunteers
- 998 people
- Sponsor
- Sun Yat-sen University
Slow Coronary Flow, Normal, or Near Normal Coronary Angiography
Effects of Nicorandil on Angina Symptoms in Patients With Coronary Slow Flow
Slow coronary flow is an angiographically diagnosed phenomenon defined as delayed opacification of epicardial arteries in the absence of significant arterial narrowing and blockade.
- Conditions
- Slow Coronary Flow, Normal, or Near Normal Coronary Angiography, Stable Angina
- Trial name
- NCT02254252
- Testing
- Nicorandil, Nitroglycerin
- Volunteers
- 54 people
- Sponsor
- Mashhad University of Medical Sciences
Coronary Artery Disease, Coronary Artery Ectasia
Evaluation of Emotional Status and Coronary Flow Characteristics by TIMI Frame Count Method
This study evaluates the effects of emotional status on coronary flow in patients undergoing elective coronary angiography. Patients whom undergoing elective coronary angiography will fulfill the Beck Anxiety Inventory, Beck…
- Conditions
- Coronary Artery Disease, Coronary Artery Ectasia, Slow-Flow Phenomenon, Endothelial Dysfunction
- Trial name
- STRAIN-TIMI (NCT02831153)
- Testing
- coronary angiography
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Ertan YETKIN
ST Segment Elevation Myocardial Infarction, Elective Percutaneous Coronary Intervention
Prevention of Coronary Slow Flow or No-Reflow During EPCI in Patients With Acute STEMI
Elective percutaneous coronary intervention (EPCI) is the common treatment of ST segment elevation myocardial infarction (STEMI).Slow flow / no-reflow phenomenon following EPCI in STEMI patients has been a serious and common…
- Trial name
- NOSLOWFLOW-Ⅱ (NCT03406832)
- Testing
- Nitroprusside Sodium, Tirofiban Hydrochloride, Heparinized saline
- Where
- 28 sites in China
- Volunteers
- 1,000 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
ST Elevation Myocardial Infarction, No-Reflow Phenomenon
Rivaroxaban for Slow Coronary Flow After PCI in STEMI
The goal of this clinical trial is to learn if drug Rivaroxaban works to improve slow flow in STEMI patients after PCI in adults. It will also learn about the safety of drug Rivaroxaban.
- Trial name
- NCT07195812
- Testing
- Dual Antiplatelet (DAPT) Therapy, Rivaroxaban
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
High-sensitivity C-reactive Protein, Carotid Stiffness
High-Sensitive CRP and Carotid Stiffness Between Patients With and Without Coronary Slow Flow
This study aims to compare the levels of high-sensitivity C-reactive protein (hs-CRP) and carotid artery stiffness between patients with coronary slow flow phenomenon (CSFP) and those with normal coronary flow.
- Conditions
- High-sensitivity C-reactive Protein, Carotid Stiffness, Coronary Slow Flow
- Trial name
- NCT07076745
- Testing
- High-sensitivity C-reactive protein, Stiffness Measurement
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Coronary Artery Disease, Microvascular Dysfunction
Mainz Intracoronary Database. The Coronary Slow-flow and Microvascular Diseases Registry
Primary goal of the registry is to collect prospective data on patients undergoing coronary angiography in Mainz. Following amendment of the procol, this study will also include patients who received an Aborb bioresorbable…
- Trial name
- MICAT (NCT02180178)
- Testing
- observational only- no intervention
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Johannes Gutenberg University Mainz
Coronary Angiography, Coronary Artery Disease
Assessment Of Total Coronary Circulation Time Using TIMI Frame Count Method (TCCT-TIMI)
The aim of this study is to evaluate and describe the total coronary circulation time (TCCT) by using TIMI frame count method in patients performed coronary angiography.
- Conditions
- Coronary Angiography, Coronary Artery Disease, Coronary Artery Ectasia, Slow-Flow Phenomenon
- Trial name
- TCCT-TIMI (NCT02818127)
- Testing
- coronary angiography
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Vascular and Molecular Cardiology Society
Human Immunodeficiency Virus (HIV), Cardiovascular Disease (CVD)
The Effects of Statin Therapy on Coronary Flow Reserve and Inflammatory Markers in HIV-Positive Patients
The purpose of this study is to determine whether the use of rosuvastatin in Human Immunodeficiency Virus (HIV) infected individuals lowers inflammation in blood vessels, improves blood circulation in the small arteries that…
- Trial name
- NCT02234492
- Testing
- Rosuvastatin
- Where
- 2 sites in Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Coronary Disease
Slow Coronary Artery Flow: Influence on Morbidity and Mortality
To compare patients with Slow Coronary Artery Flow to patients with normal flow and to determine whether there is a difference in their future incidence of heart disease.
- Trial name
- NCT00603226
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hillel Yaffe Medical Center
ST Segment Elevation Myocardial Infarction, Coronary Slow Flow Phenomenon
Efficacy of Intracoronary Infusion of Different Medicine in STEMI Patients With CSFP
The study intends to evaluate the efficacy of different medicine delivering by targeted perfusion catheter in coronary administration on coronary blood flow in STEMI patients with CSFP.
- Trial name
- NCT03296670
- Testing
- Alprostadil, Nitroglycerin
- Where
- China
- Volunteers
- 57 people
- Sponsor
- RenJi Hospital
Coronary Microvascular Disease, Myocardial Infarction
Treatment of Slow-flow After Primary Percutaneous Coronary Intervention With Flow-mediated Hyperemia
A total of 100 patients with ST-elevation myocardial infarction (STEMI) presenting slow-flow after primary-percutaneous coronary intervention (PPCI) will be randomized to pharmacologic treatment with hyperemic drugs versus…
- Trial name
- RAIN FLOW (NCT04685941)
- Testing
- Drug-mediated hyperemia, Flow-mediated hyperemia
- Where
- 5 sites in Spain
- Volunteers
- 67 people
- Sponsor
- Fundación EPIC
Ischemic Heart Disease
Phase II Study for the Diagnosis and Functional Assessment of CAD Using Transthoracic-Echodoppler
The purpose of this study is to evaluate the efficacy and tolerance of a dipyridamole/adenosine combination given intravenously, as a slow bolus and at low doses to adenosine alone (given at its recommended dosage adjusted to…
- Trial name
- NCT01593644
- Testing
- adenosine + dipyridamole
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Adenobio N.V
Coronary Angiography
"Normal Coronary Artery" With Slow Flow Improved by Adenosine Injection, Dipyridamole Treatment and Clinical Follow-up
The investigators will investigate patients undergoing coronary angiography with normal coronary but slow blood flow that was normalized after adenosine injection into the coronary artery.
- Trial name
- NCT00960817
- Testing
- Statin, aspirin, Dipyridamole
- Where
- Israel
- Sponsor
- Hillel Yaffe Medical Center
Coronary Artery Disease, Atherosclerosis, Coronary
HIV Infection And Evolvement of Atherosclerotic Plaque
In a prospective multi-center observational study, 200 HIV-infected patients treated with antiretroviral treatment (ART) and who suffered from coronary artery disease (CAD) will be enrolled.
- Conditions
- Coronary Artery Disease, Atherosclerosis, Coronary, Hiv, HIV Infections
- Trial name
- HIVE (NCT04810364)
- Testing
- Quantitative coronary angiography, intravascular imaging with percutaneous intervention
- Where
- 2 sites in Russia
- Volunteers
- 1,000 people
- Sponsor
- Central Clinical Hospital of the Russian Academy of Sciences
Acute Myocardial Infarction, Percutaneous Coronary Intervention
Effects of Different Vasodilators on Coronary No-reflow During primAry percuTaneous Coronary intErvention in Patients With Acute Myocardial Infarction
The purpose of this study is to evaluate the efficacy of three different vasodilators including diltiazem, verapamil and nitroglycerin for reversal of no-reflow/slow-flow during direct percutaneous coronary intervention for acute…
- Trial name
- EDUCATE-AMI (NCT00712894)
- Testing
- Diltiazem, Verapamil, Nitroglycerin
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Fudan University
HIV
Sildenafil to Treat HIV-Associated Pulmonary Hypertension
This study will examine how blood pressure in the lungs is controlled in healthy people, people with HIV and people with HIV and pulmonary artery hypertension (high blood pressure in the lungs, also called PAH).
- Trial name
- NCT00327080
- Testing
- MRI, L-NMMA, Acetylcholine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
ST Elevation Myocardial Infarction (STEMI), Acute Coronary Syndromes (ACS)
A Single-Center, Retrospective, Propensity-Score-Matched Cohort Study Comparing Drug-Coated Balloon Versus Drug-Eluting Stent for Reducing Immediate Post-Procedural Slow-Flow/No-Reflow in Acute ST-Elevation Myocardial Infarction Patients With High Thrombus Burden
This is a single-center, retrospective, propensity-score-matched observational study. It aims to compare the rate of immediate slow-flow or no-reflow after percutaneous coronary intervention (PCI) between drug-coated balloon…
- Trial name
- STEMI-DCB (NCT07806370)
- Testing
- Drug-Coated Balloon (DCB), Drug-Eluting Stent (DES)
- Where
- China
- Volunteers
- 668 people
- Sponsor
- Xijing Hospital
ST Segment Elevation Myocardial Infarction, Primary Percutaneous Coronary Intervention
Prevention of Coronary Slow Flow or No-Reflow During PPCI in Patients With Acute STEMI
Primary percutaneous coronary intervention (PPCI) is the gold standard of treatment of ST segment elevation myocardial infarction (STEMI).Slow flow / no-reflow phenomenon following PPCI in STEMI patients has been a serious and…
- Trial name
- NOSLOWFLOW-Ⅰ (NCT03406819)
- Testing
- Nitroprusside Sodium, Tirofiban Hydrochloride, Heparinized saline
- Where
- 28 sites in China
- Volunteers
- 1,000 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
ST-Segment Elevation Myocardial Infarction (STEMI), No-Reflow Phenomenon
Adenosine Pre-Medication in Primary Percutaneous Coronary Intervention
Primary objective of the study is to evaluate the impact of adenosine pre-medication on incidence of slow flow/no-reflow after primary percutaneous coronary intervention.
- Conditions
- ST-Segment Elevation Myocardial Infarction (STEMI), No-Reflow Phenomenon, Coronary Slow Flow, Acute Myocardial Infarction
- Trial name
- AMPACT (NCT07536802)
- Testing
- Adenosine pre-medication, Standard care
- Where
- 2 sites in Pakistan
- Volunteers
- 1,148 people
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan