Clinical trials: Coronary Stent Implantation
Coronary Artery Perforation
Covered Stents in Treatment of Coronary Artery Perforation
Covered stents have been mainly used for treatment of potentially life-threatening coronary artery perforation and coronary artery aneurysm.
- Trial name
- CRACK (NCT04630314)
- Testing
- Percutaneus Coronary Intervention
- Where
- 6 sites in Poland
- Volunteers
- 119 people
- Sponsor
- Medical University of Silesia
Major Adverse Cardiovascular and Cerebrovascular Events (MACCE)
Observational Prospective Study OPTIMA II - Follow-up
The current follow-up study was planned to reveal the rates of Major Adverse Cardiovascular and Cerebrovascular Events (MACCE) during 4-year follow-up in patients participated in OPTIMA study.
- Trial name
- OPTIMAII (NCT02099565)
- Where
- Russia
- Volunteers
- 572 people
- Sponsor
- AstraZeneca
Acute Coronary Syndrome
Soluble Receptors for Advanced Glycation End-Products and PCI
It is hypothesized that patients with low pre-PCI serum levels of sRAGE should receive DES implantation and/ or procedures taken to increase serum levels of sRAGE and/ or decrease the serum levels of AGE.
- Trial name
- NCT01867034
- Testing
- Drug Eluting Stent, Bare Metal Stent
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Saskatchewan
Coronary Stent Restenosis
Effect of Metal Skin Sensitivity on Restenosis After Stent Implantation
This trial is intended to find wether there is a connection between allergy to metals and reooclusion of stents in the coronary arteries
- Trial name
- NCT00226525
- Testing
- skin sensitivity test
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Hadassah Medical Organization
Coronary Artery Disease, Atherosclerosis
Biological Efficacy of Clopidogrel After Implantation of Drug-eluting Stents (SPACE)
The risk of thrombotic complications after implantation of drug-eluting stents (DES) may be increased in patients with diabetes mellitus (DM) or metabolic syndrome (MS).
- Conditions
- Coronary Artery Disease, Atherosclerosis, Diabetes Mellitus, Metabolic Syndrome X
- Trial name
- SPACE (NCT00298428)
- Testing
- blood samples
- Where
- 2 sites in France
- Volunteers
- 159 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Disease, Diabete Mellitus
The Efficacy of SGLT-2 Inhibitor in Patients With CAD and DM Undergoing PCI.
The study is to compare the effects of SGLT-2 inhibitors and other oral hypoglycemic agents in patients with coronary heart disease and diabetes mellitus undergoing percutaneous coronary intervention.
- Trial name
- NCT05333159
- Testing
- SGLT2 inhibitor
- Where
- China
- Volunteers
- 1,424 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease
Aroxxen® Inhalation for Cardioprotection After Elective PCI With Stent Implantation
This is an open-label, randomized, multicenter Phase II clinical study designed to evaluate the cardioprotective effect, to determine the optimal dosages and duration of inhalation, and to assess the clinical safety of the…
- Trial name
- NCT07397351
- Testing
- Aroxxen
- Where
- Russia
- Volunteers
- 180 people
- Sponsor
- Research Institute of Geroprotective Technologies
Coronary Artery Disease, Coronary Restenosis
Systemic Treatment With Everolimus for the Prevention of MACE After Bare Metal Stent Implantation
The purpose of the present study is to provide the first in-human safety and efficacy evaluations of systemic oral anti-proliferative Everolimus therapy compared to placebo in patients treated by bare metal stents for significant…
- Trial name
- NCT00426049
- Testing
- Everolimus
- Where
- Germany
- Volunteers
- 484 people
- Sponsor
- German Heart Institute
Coronary Disease
Optimal Physiologic Intravascular Ultrasound Imaging Criteria After Drug Eluting Stent Implantation
Invasive imaging criteria of the Coronary arteriography (CAG) and intravascular ultrasound imaging (IVUS), satisfying procedural optimization after drug eluting stent (DES) implantation, were used in < 10% DS by CAG and 5-5.5mm2…
- Trial name
- NCT01667757
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Inje University
Coronary Artery Disease
Effect of Different Anti-platelet Strategies on the Long-term Outcome After Sirolimus Drug-eluting Stent Implantation
The study aims to assess the effectiveness of dual antiplatelet therapy, aspirin alone versus steeply discontinued clopidogrel plus aspirin in preventing clinical MACE events.Our subject is beyond a 12-month period patients…
- Trial name
- EASTS (NCT01233167)
- Testing
- clopidogrel
- Volunteers
- 5,232 people
- Sponsor
- Sir Run Run Shaw Hospital
Coronary Artery Disease
Motivational Interviewing After Coronary Stenting
This study aimed to examine the effect of motivational interviewing on healthy lifestyle behaviors and biochemical parameters in patients who underwent stent implantation after coronary angiography.
- Trial name
- NCT07659951
- Testing
- Motivational Interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Biruni University
Coronary Artery Disease
Stenting With or Without Coating Compared With Angioplasty in Non-benestent Disease
The purpose of this study is to evaluate the clinical and angiographic outcome of implantation of stents eluting or not eluting Sirolimus in patients with complex coronary artery lesions suitable for percutaneous coronary…
- Trial name
- NCT00192881
- Testing
- Bx Sonic & Cypher stent from Cordis
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronary Artery Disease
1-month vs 12-month DAPT for ACS Patients Who Underwent PCI Stratified by IVUS: IVUS-ACS and ULTIMATE-DAPT Trials
Prospective, multicenter, randomized, double-blind, placebo-controlled trials.
- Trial name
- NCT03971500
- Testing
- AntiPlatelet therapy, Percutaneous coronary intervention
- Where
- China
- Volunteers
- 3,710 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Myocardial Infarction
Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction
The primary objectives of the trial are: 1. To establish the safety and efficacy of the use of bivalirudin (+ bail-out GP IIb/IIIa inhibitors) compared to the use of unfractionated heparin + GP IIb/IIIa inhibitors in patients…
- Trial name
- NCT00433966
- Testing
- Bivalirudin, Unfractionated heparin, Bare metal stent
- Where
- United States
- Volunteers
- 3,602 people
- Sponsor
- Cardiovascular Research Foundation, New York
Coronary Artery Disease
Clopidogrel Use and Long-term Safety After Drug-Eluting Stents Implantation
The purpose of ZEST-LATE (Evaluation of the Long-term Safety After Zotarolimus-Eluting Stent, Sirolimus-Eluting Stent, or PacliTaxel-Eluting Stent Implantation for Coronary Lesions - Late Coronary Arterial Thrombotic Events)…
- Trial name
- ZEST-LATE (NCT00590174)
- Testing
- Aspirin, Aspirin,Clopidogrel
- Where
- 20 sites in South Korea
- Volunteers
- 1,175 people
- Sponsor
- Seung-Jung Park
Coronary Artery Disease
Optimization of Percutaenous Coronary Intervention With Liberal Use of Post-dilatation
To achieve optimal long-term clinical results after percutaneous coronary intervention (PCI), adequate deployment of stents is essential.
- Trial name
- OPTIMIZE-PCI (NCT06558474)
- Testing
- Liberal post-dilatation strategy during PCI
- Where
- Netherlands
- Volunteers
- 12,000 people
- Sponsor
- Cathreine BV
ST Segment Elevation Myocardial Infarction
DANish Study of Optimal Acute Treatment of Patients With ST-elevation Myocardial Infarction
This study focuses on Cardioprotective strategies.
- Trial name
- DANAMI-3 (NCT01435408)
- Testing
- Conventional primary PCI, Ischemic postconditioning., Deferred stenting in primary PCI.
- Where
- 5 sites in Denmark
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronary Artery Disease, Atheroscleroses, Coronary
Long Term Follow-up of Comparison of Clopidogrel vs. Aspirin Monotherapy After Drug-eluting Stent Implantation
This is an retrospective extended study of a randomized clinical trial (The HOST-EXAM trial ClinicalTrials.gov Identifier: NCT02044250).
- Trial name
- HOST-EXAM-EX (NCT05567536)
- Testing
- Antiplatelet Agents
- Volunteers
- 5,530 people
- Sponsor
- Seoul National University Hospital
Acute Coronary Syndrome, Acute Myocardial Infarction
ShorT and OPtimal Duration of Dual AntiPlatelet Therapy-2 Study for the Patients With ACS
The purpose of this study is to evaluate the safety of reducing dual antiplatelet therapy (DAPT) duration to 1 month after implantation of the everolimus-eluting cobalt-chromium stent (CoCr-EES) under the setting of acute…
- Conditions
- Acute Coronary Syndrome, Acute Myocardial Infarction, Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- STOPDAPT-2 ACS (NCT03462498)
- Testing
- 1-months DAPT, 12-month DAPT
- Where
- Japan
- Volunteers
- 3,008 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Coronary Heart Disease, Stable Angina Pectoris
BuMA OCT Study(A Comparative Evaluation of the Extent of Neointima Formation at 3 Months After Implantation Using OCT)
The objective of this study is a comparative evaluation of BuMA stent and of EXCEL stent in terms of the extent of neointima formation at 3 months after implantation using OCT.
- Conditions
- Coronary Heart Disease, Stable Angina Pectoris, Unstable Angina Pectoris, Silent Myocardial Ischemia
- Trial name
- NCT01752582
- Testing
- BuMA stent, EXCEL stent
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sino Medical Sciences Technology Inc.