Clinical trials: Coronary Stent Occlusion
Coronary Artery Disease
A New Strategy Regarding Discontinuation of Dual Antiplatelet
Drug-eluting stents (DES), markedly reducing the neointimal hyperplasia after stent implantation compared with bare-metal stents (BMS), have improved angiographic and clinical outcomes in the complex lesions and patients with…
- Trial name
- NCT01145079
- Testing
- Zotarolimus-eluting stent, Zotarolimus-eluting stent for ACS and DM, Everolimus-eluting stent for long lesion
- Where
- South Korea
- Volunteers
- 982 people
- Sponsor
- Yonsei University
Coronary Atherosclerosis Due to Calcified Coronary Lesion, Chronic Total Occlusion of Coronary Artery
The XLIMUS-DES in Very Complex Lesions
Stent delivery failure occurs in 4% of all percutaneous coronary interventions (PCI) and >90% of these failures are due to vessel tortuosity and/or calcification.
- Trial name
- NCT02360020
- Testing
- XLimus
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Clinica Mediterranea
Coronary Occlusion, Thrombosis (Stent Thrombosis)
XIENCE V Everolimus Eluting Coronary Stent System (EECSS) China: Post-Approval Randomized Control Trial (RCT)
This is a prospective, randomized, active-controlled, open label, parallel two-arm, multi-center, post-approval study descriptively comparing the XIENCE V EECSS to the CYPHER SELECT PLUS Sirolimus-Eluting Coronary Stent System…
- Conditions
- Coronary Occlusion, Thrombosis (Stent Thrombosis), Vascular Disease, Myocardial Ischemia
- Trial name
- NCT01178268
- Testing
- XIENCE V EECSS, CYPHER SELECT PLUS SECSS
- Where
- 2 sites in China
- Volunteers
- 546 people
- Sponsor
- Abbott Medical Devices
Myocardial Infarction, Coronary Artery Disease
The Viability-Guided Angioplasty After Acute Myocardial Infarction-Trial (The VIAMI-Trial)
The VIAMI-trial investigates the effects of balloon angioplasty with stenting of the infarct-vessel in the early phase after acute myocardial infarction.
- Trial name
- NCT00149591
- Testing
- coronary balloon-angioplasty with stenting
- Where
- 12 sites in Netherlands
- Volunteers
- 300 people
- Sponsor
- Netherlands Heart Foundation
Coronary Artery Disease
Anti Ischemic Effects of Abciximab in Angioplasty and Stenting Patients
AIR STUDY TITLE: Anti-Ischemic effects of Abciximab(Reopro) PATIENT POPULATION: Patients undergoing PCI(an interventional procedure placing a small stent/metallic tube to keep a narrowed artery in your heart open) and either on a…
- Trial name
- AIR (NCT00379418)
- Testing
- Abciximab
- Where
- 2 sites in United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Emory University
Coronary Artery Disease, Intracoronary Lithotripsy
Influence of Calcium Pattern on Plaque Modification Achieved With Intracoronary Lithotripsy
Calcified coronary artery disease is a frequently encountered problem that can lead to poorer outcomes for patients undergoing PCI.
- Conditions
- Coronary Artery Disease, Intracoronary Lithotripsy, Optical Coherence Tomography, Percutaneous Coronary Intervention
- Trial name
- NCT04698902
- Testing
- Intracoronary lithotripsy
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Fundacion Investigacion Interhospitalaria Cardiovascular
Cardiovascular Diseases, Coronary Disease
Angioplasty and Heart Stents to Treat Individuals With an Occluded Artery Following a Heart Attack
The purpose of this study is to evaluate arterial patency and left ventricular ejection fraction by examining angiographic data one year following a heart attack and treatment with late revascularization.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- TOSCA-2 (NCT00025766)
- Testing
- PCI with stenting, Optimal Medical Therapy
- Where
- Canada
- Volunteers
- 380 people
- Sponsor
- University Health Network, Toronto
Coronary Artery Disease
Elixir Medical Clinical Evaluation of the Novolimus-Eluting Coronary Stent System: A Randomized Study "EXCELLA II STUDY"
Randomized Study To evaluate the safety and effectiveness of the Elixir Medical DESyne Novolimus-Eluting Coronary Stent System with Durable Polymer through the assessment of clinical, angiographic and IVUS endpoints as compared…
- Trial name
- NCT00792753
- Testing
- Medtronic Endeavor Coronary Stent System, DESyne BD Novolimus Stent System, DESyne Novolimus Stent System
- Where
- 8 sites in Australia, Belgium and 6 more
- Volunteers
- 360 people
- Sponsor
- Elixir Medical Corporation
Coronary Artery Disease
Comparison of BuMA eG Based BioDegradable Polymer Stent With EXCEL Biodegradable Polymer Sirolimus-eluting Stent in "Real-World" Practice
PANDA III is sought to investigate the safety and efficacy of a PLGA-polymer with electro-grafting base layer sirolimus-eluting stent (SES) versus a PLA-polymer SES at 12 months follow-up.
- Trial name
- PANDA-III (NCT02017275)
- Testing
- BuMA, EXCEL
- Where
- China
- Volunteers
- 2,348 people
- Sponsor
- Sino Medical Sciences Technology Inc.
Coronary Disease
Safety and Efficacy Study of the Nile PAX Drug-Eluting Coronary Bifurcation Stent
The purpose of this trial is to assess the safety and efficacy of the Nile PAX® Drug Eluting Coronary Bifurcation Stent System for the treatment of single de novo bifurcation lesions in native coronary arteries with a main branch…
- Trial name
- BIPAX (NCT01308229)
- Testing
- Nile PAX® paclitaxel-eluting coronary stent
- Where
- 10 sites in Brazil, Bulgaria and 5 more
- Volunteers
- 102 people
- Sponsor
- MINVASYS
Coronary Occlusions
AngiographiC Evaluation of the Everolimus-Eluting Stent in Chronic Total Occlusions - the ACE-CTO Study
Chronically total occlusions (CTO) are difficult to treat and have high risk for restenosis. Although everolimus-eluting stents (EES) [(Xience, Abbott Vascular) or Promus (Boston Scientific)] are very promising for the treatment…
- Trial name
- ACE-CTO (NCT01012869)
- Testing
- everolimus-eluting stent
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- North Texas Veterans Healthcare System
Coronary Artery Disease, Coronary Artery Stenosis Stent
Deep Learning CAD Screening on Chest CT
Coronary artery disease (CAD) is one of the leading causes of death worldwide. Many people have early atherosclerosis without symptoms, and some may develop significant coronary stenosis before any warning signs appear.
- Trial name
- CAD-AI (NCT07181512)
- Testing
- Deep Learning Analysis of Non-contrast Chest CT
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yifan Guo
Coronary Atherosclerosis, Angina Pectoris
Trial of Drug Eluting Stent Versus Bare Metal Stent to Treat Coronary Artery Stenosis
Stenosis of the coronary arteries may be treated by balloon dilatation followed by the implantation of a metal stent. However, restenosis occurs in 10-20% of patients treated with bare metal stents (BMS).
- Conditions
- Coronary Atherosclerosis, Angina Pectoris, Myocardial Infarction
- Trial name
- NORSTENT (NCT00811772)
- Testing
- Percutaneous coronary intervention (PCI)
- Where
- 8 sites in Norway
- Volunteers
- 9,013 people
- Sponsor
- University of Tromso
Coronary Artery Disease, Ischemic Heart Disease
Culprit-first in Primary Percutaneous Coronary Intervention
The aim of this study is to assess the impact of culprit-first versus culprit-last percutaneous coronary intervention on the door to balloon time and clinical outcomes in patients with ST-elevation myocardial infarction.
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Myocardial Infarction, STEMI
- Trial name
- NCT05415085
- Testing
- Culprit-first PCI
- Where
- Israel
- Volunteers
- 106 people
- Sponsor
- Shaare Zedek Medical Center
Coronary Artery Disease, Myocardial Ischemia
Genoss DES Prospective Multicenter Registry
This registry is a clinical post-market evaluation of the Genoss DES in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Myocardial Infarction
- Trial name
- NCT03045913
- Testing
- Genoss DES
- Where
- 17 sites in South Korea
- Volunteers
- 2,000 people
- Sponsor
- Young Jin Youn, MD, PhD
Coronary Artery Disease
Noninferiority Trial Of Sirolimus With Ascorbic Acid Versus Everolimus in All-comers
The objective of this study is to demonstrate the primary hypothesis that, in patients with chronic and acute coronary syndromes requiring percutaneous coronary intervention (PCI), the novel sirolimus-ascorbic acid eluting stent…
- Trial name
- NOVA (NCT07566091)
- Testing
- Sirolimus-Ascorbic Acid Eluting Stent, Everolimus-Eluting Stent
- Where
- South Korea
- Volunteers
- 2,034 people
- Sponsor
- Jung-min Ahn
Coronary Artery Disease
Optimization of Percutaenous Coronary Intervention With Liberal Use of Post-dilatation
To achieve optimal long-term clinical results after percutaneous coronary intervention (PCI), adequate deployment of stents is essential.
- Trial name
- OPTIMIZE-PCI (NCT06558474)
- Testing
- Liberal post-dilatation strategy during PCI
- Where
- Netherlands
- Volunteers
- 12,000 people
- Sponsor
- Cathreine BV
Coronary Artery Disease
Single-centre, Registry Trial, the Patients Presented With Stable Coronary Artery Disease
This is a prospective study to analyze the outcome of provisional main vessel stenting on side branch by utilizing Two-Dimensional (2D) and Three-Dimensional (3D) frequency domain optical coherence tomography (FD-OCT).
- Trial name
- NCT02364778
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Coronary Artery Disease
The ATLANTA First in Man Study of the Catania Stent
To evaluate the short-term and mid-term safety and efficacy of the Catania coronary stent for the treatment of up to two de novo lesions in native coronary arteries.
- Trial name
- ATLANTA (NCT00799032)
- Testing
- PCI
- Where
- Italy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- CeloNova BioSciences, Inc.
Coronary Artery Disease, Acute Coronary Syndrome
Polymer-free Sirolimus Eluting Stent: Real-world Investigation of Safety and Outcomes
POLARIS is a prospective, single-centre, single-arm observational pilot registry evaluating the real-world safety and efficacy of the Focus np (Abluminus np, Concept Medical, Tampa, FL, USA) polymer-free sirolimus-eluting stent…
- Conditions
- Coronary Artery Disease, Acute Coronary Syndrome, Myocardial Infarction, Stent Thrombosis
- Trial name
- POLARIS (NCT07563231)
- Testing
- Polymer-free sirolimus-based submicron carrier-eluting stent Focus np (Abluminus np, Concept Medical, Tampa, FL, USA)
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Dorian Garin