Clinical trials: Coronavirus (SARS-CoV)
Patients Undergoing Cardiac or Thoracic Surgery
Patient Outcome of Cardiac Surgery During the COVID-19 Pandemic
This study will describe the recovery process of patients undergoing cardiac surgery during the covid-19 pandemic. This will focus on hemodynamic failure and organ dysfunction after surgery.
- Trial name
- NCT04389463
- Testing
- No intervention
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Nantes University Hospital
SARS-CoV 2
IgG/IgM Antibody Test in Patients Who Have Tested Negative or Positive for COVID-19 With the Standard Method of COVID19 Testing.
The purpose of this study is to evaluate point of care SARS-Cov2 Virus IgG/IgM rapid test cassette Clungene test and correlate it with the standard method of testing in inpatients who have tested positive or negative for COVID19.
- Trial name
- NCT04402814
- Testing
- Clungene rapid test cassette
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- Fadi Haddad, M.D.
COVID-19, SARS-CoV 2
EuRopean Study of MAjor Infectious Disease Syndromes Related to COVID-19
Background Rapid European COVID-19 Emergency Research response (RECoVER), is a project involving 10 international partners that has been selected for funding by the European Union under the Horizon 2020 research framework…
- Trial name
- MERMAIDS 2 (NCT04364711)
- Where
- 11 sites in Estonia, Greece and 6 more
- Volunteers
- 300 people
- Sponsor
- UMC Utrecht
SARS-CoV Infection, Covid19
Study of SARS-CoV2 Virus (COVID-19) Seroprevalence Among Lyon-Bron Military Health Schools Personnel
Emerging in China in December 2019, Covid-19, whose pathogen is SARS-Cov-2, was declared a global pandemic in March 2020. The clinical presentation is highly variable, ranging from asymptomatic forms to acute respiratory distress…
- Trial name
- SeroCovEms (NCT04516928)
- Testing
- Anti-SARS-CoV2 Serology, Questionnaire
- Where
- France
- Volunteers
- 392 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Covid19, Coronavirus
Serology to COVID-19 for Recording Exposures and Evaluating Needs
As the global and pandemic spread of the novel coronavirus (SARS-CoV-2, COVID-19) continues, many knowledge gaps remain with regard to the epidemiology and transmission of infection, as well as the normal immunological responses…
- Conditions
- Covid19, Coronavirus, SARS-CoV Infection
- Trial name
- SCREEN (NCT04566965)
- Testing
- SARS-CoV-2
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
SARS-CoV 2, COVID-19
Convalescent Plasma Trial in COVID -19 Patients
Plasma therapy using convalescent plasma has been shown to be effective in severe acute respiratory syndrome, Ebola virus infection and in H1N1 influenza.
- Trial name
- NCT04356534
- Testing
- plasma therapy using convalescent plasma with antibody against SARS-CoV-2, Routine care for COVID-19 patients
- Where
- Bahrain
- Volunteers
- 40 people
- Sponsor
- Royal College of Surgeons in Ireland - Medical University of Bahrain
COVID-19, Fatigue
Differential Diagnosis of Persistent COVID-19 by Artificial Intelligence
The pandemic caused by SARS-CoV-2 infection has resulted, in addition to the well-known acute symptoms, in the emergence of persistent, diffuse and heterogeneous symptoms referred to as persistent COVID.
- Conditions
- COVID-19, Fatigue, Distress Respiratory Syndrome, Cognitive Dysfunction
- Trial name
- DICOPERIA (NCT05629793)
- Testing
- Experimental tests
- Where
- 7 sites in Spain
- Volunteers
- 136 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Arbovirus Infections, SARS-CoV Infection
Human Epidemiology of Newly Identified Arboviruses
A local network is being set up to study the impact of arboviruses in our region. It is committed to a one-health approach, in particular with research without a priori for new viruses hosted among vectors and wildlife.
- Trial name
- ARBODOCC (NCT04954352)
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
SARS-CoV2 Infection, COVID-19
Prevalence and Impact of COVID-19 on Maternal and Infant Health in African Populations
There is growing evidence that COVID-19 threatens maternal and perinatal health. Pregnant women are at higher risk of severe complications (severe pneumonia, hospitalizations, intensive care unit admission, invasive mechanical…
- Trial name
- MA-CoV (NCT05303168)
- Where
- 2 sites in Gabon, Mozambique
- Volunteers
- 1,000 people
- Sponsor
- Barcelona Institute for Global Health
Covid19, SARS-CoV Infection
The DAWN Antivirals Trial for Ambulatory COVID-19 Patients
This is a prospective, placebo controlled, individually randomized controlled phase III trial in Primary Care, assessing the efficacy of antivirals, i.e. camostat and molnupiravir, in accelerating recovery in Covid-19 patients.
- Trial name
- DAWN (NCT04730206)
- Testing
- Camostat, Molnupiravir
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- KU Leuven
SARS-CoV Infection
Comparison of Strategies Based on RT-PCR or Antigenic Test for the Screening of SARS-CoV-2 Infection (COVID-19).
The virological diagnosis of SARS-CoV-2 infection is pivotal for the control of the outbreak by large screening of a- or pauci-symptomatic subjects.
- Trial name
- AutoCoV (NCT04859023)
- Testing
- saliva sample combined to an anterior nare self-swabbing (Self-samples), saliva sample (Self-sample), Survey of SARS-COV-19 knowledge
- Where
- France
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Coronavirus, Respiratory Distress Syndrome
LIBERATE Trial in COVID-19
The study aims to evaluate the reduction in severity and progression of lung injury with three doses of lipid ibuprofen in patients with SARS-CoV-2 infections.
- Conditions
- Coronavirus, Respiratory Distress Syndrome, SARS-CoV Infection
- Trial name
- LIBERATE (NCT04334629)
- Testing
- Ibuprofen
- Where
- United Kingdom
- Sponsor
- King's College London
Covid19, SARS-CoV Infection
Epidemiologic Assessment of SARS-CoV-2 (COVID-19) Prevalence in Minnesota
The purpose of this epidemiologic study is to estimate the prevalence and incidence of anti-SARS-CoV-2 antibodies in at-risk, exposed, affected populations.
- Conditions
- Covid19, SARS-CoV Infection, SARS-CoV-2, Corona Virus Infection
- Trial name
- NCT04473183
- Testing
- Specimen Collection, Surveys
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
SARS-CoV Infection, Severe Acute Respiratory Syndrome (SARS) Pneumonia
Chloroquine Diphosphate for the Treatment of Severe Acute Respiratory Syndrome Secondary to SARS-CoV2
In December 2019, the Municipal Health Committee of Wuhan, China, identified an outbreak of viral pneumonia of unknown cause. This new coronavirus was called SARS-CoV-2 and the disease caused by that virus, COVID-19.
- Trial name
- CloroCOVID19 (NCT04323527)
- Testing
- Chloroquine diphosphate
- Where
- Brazil
- Volunteers
- 278 people
- Sponsor
- Fundação de Medicina Tropical Dr. Heitor Vieira Dourado
COVID, SARS-CoV 2
Transfusion of Convalescent Plasma for the Early Treatment of Patients With COVID-19
No specific therapeutic agents or vaccines for COVID-19 are available. Several therapies, are under investigation, but the antiviral efficacy of these drugs is not yet known.
- Trial name
- TSUNAMI (NCT04393727)
- Testing
- CONVALESCENT PLASMA
- Where
- Italy
- Volunteers
- 1 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
SARS CoV 2 Infection
Study to Evaluate Safety, Tolerability, Pharmacokinetics and the Food Effect on PK of ASC10 Tablets in Healthy Subjects
This is a phase I, randomized, double-blind, placebo-controlled study to evaluate safety, tolerability, and pharmacokinetics of ASC10 tablets and an open-label, crossover design to evaluate the food effect on PK of ASC10 in…
- Trial name
- NCT05523141
- Testing
- ASC10
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ascletis Pharmaceuticals Co., Ltd.
COVID-19, SARS CoV 2 Infection
STREngthening COronavirus Disease 2019 (COVID-19) Surveillance in Africa
The aim of this observational study was to develop, with the intended users, an epidemic surveillance and response system that will be effective, sensitive, coordinated and appropriate.
- Conditions
- COVID-19, SARS CoV 2 Infection, COVID-19 Pandemic
- Trial name
- STREESCO (NCT06170320)
- Where
- Benin
- Volunteers
- 7,000 people
- Sponsor
- Institut de Recherche pour le Developpement
COVID-19, SARS-CoV 2
Trial to Promote Recovery From COVID-19 With Endocrine Therapy
Patients with COVID-19 requiring inpatient hospitalization will be randomized to treatment with standard of care or standard of care + bicalutamide.
- Trial name
- RECOVER (NCT04374279)
- Testing
- Bicalutamide 150 Mg Oral Tablet
- Where
- United States
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
SARS-CoV-2 Virus Infection
COV-COMPARE Immunogenicity of Vaccine VLA2001 Compared to AZD1222
This is a multicentre, randomized, observer-blind, active-controlled, superiority, study in adults to compare the immunogenicity of VLA2001 to AZD1222 in terms of GMT of SARS-CoV-2-specific neutralising antibodies.
- Trial name
- COV-COMPARE (NCT04864561)
- Testing
- VLA2001, AZD1222, VLA2001 - adolescent part
- Where
- 31 sites in United Kingdom
- Volunteers
- 4,034 people, healthy volunteers welcome
- Sponsor
- Valneva Austria GmbH
COVID-19
The Effects of a Multi-factorial Rehabilitation Program for Healthcare Workers Suffering From Post-COVID-19 Fatigue Syndrome
The SARS-CoV2 pandemic has kept the world in suspense for over a year now. Almost 100 million people around the world have contracted COVID-19 to date and over 2 million people have died of COVID-19 by the end of January 2021.
- Trial name
- NCT04841759
- Testing
- Exercise
- Where
- Austria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna