Clinical trials: Coronavirus Disease (COVID)19
Covid19
Cardiac Assessment After Covid-19 Disease in Elite Altheltic Population
COVID-19 infection coud induce cardiac injuries. Before returning to sport, cardiac evaluation is recommended by sports federations, based on the precautionary principle and the opinion of expert consensus.
- Trial name
- CADE (NCT04653857)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Montpellier
Covid19, Covid-19 ARDS
Efficacy and Safety of Remdesivir and Tociluzumab for the Management of Severe COVID-19: A Randomized Controlled Trial
This randomized clinical trial was designed and intended to evaluate the efficacy of Remdesivir and Tocilizumab as a treatment for severe Acute Respiratory Distress Syndrome (ARDS) caused by Coronavirus disease 2019 (COVID-19).
- Trial name
- NCT04678739
- Testing
- Remdesivir, Tocilizumab
- Where
- 4 sites in Bangladesh
- Volunteers
- 205 people
- Sponsor
- M Abdur Rahim Medical College and Hospital
Pneumonia, Viral, Corona Virus Infection
Convalescent Antibodies Infusion in COVID 19 Patients
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which originated in Wuhan, China, has become a major concern all over the world.
- Trial name
- NCT04418531
- Testing
- Anti-coronavirus antibodies (immunoglobulins) obtained with DFPP form convalescent patients
- Sponsor
- Piero Luigi Ruggenenti
PASC Post Acute Sequelae of COVID 19
Physiological and QoL Benefits of Qi-Gong in Post-acute Sequelae of Covid-19
The goal of this clinical trial is to determine whether Qi-Gong can improve physiological function and quality of life (QoL) in individuals with post-acute sequelae of SARS-CoV-2 infection (PASC).
- Trial name
- QG-PASC (NCT06879925)
- Testing
- QI-GONG and control
- Where
- 2 sites in Taiwan
- Volunteers
- 80 people
- Sponsor
- POCHIWU
Postnatal Depression
Impact of Giving Birth During the Covid 19 Pandemia on Postnatal Women's Depression
Postnatal depression is an important problematic in French population with approximatively 10 -20% of women who suffer from postnatal depression. This pathology may have strong negative impact on both women and neonate's health.
- Trial name
- DEPRECOVID (NCT04368208)
- Testing
- Assessment of postnatal depression using the the Edinburgh questionnaire between 4 and 6 weeks after delivery
- Where
- France
- Volunteers
- 501 people
- Sponsor
- Poitiers University Hospital
COVID - 19
Vitamin E Supplementation As Adjunctive Therapy To Lower Inflammation In COVID-19 Patients
Since the first reported case of the novel coronavirus (SARS-CoV-2) in humans at the end of 2019 in Wuhan, the virus had infected approximately 100 million individuals.
- Trial name
- VITEC (NCT07412574)
- Testing
- Patients were randomly assigned, under a double-blind design, α-Tocopherol group (n = 22)
- Where
- Mexico
- Volunteers
- 56 people
- Sponsor
- Universidad Veracruzana
Mortality, Intensive Care Unit
Effect of Favipiravir on Mortality in Patients With COVID-19 at a Tertiary Center Intensive Care Unit
Effect of Favipiravir and Lopinavir-Ritonavir on Mortality in a Tertiary Center Intensive Care Unit: Single Center Experience
- Trial name
- NCT04645433
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Covid19, Thrombosis
Enoxaparin at Prophylactic or Therapeutic Doses in COVID-19
SINGLE CENTER PHASE III INTERVENTIONAL RANDOMIZED CONTROLLED TRIAL comparing efficacy and safety of enoxaparin at prophylactic dose (standard treatment) and enoxaparin at therapeutic dose (OFF-LABEL treatment) in 300 COVID-19…
- Trial name
- EMOS-COVID (NCT04646655)
- Testing
- Enoxaparin
- Where
- Italy
- Volunteers
- 142 people
- Sponsor
- ASST Fatebenefratelli Sacco
COVID 19, Influenza
COVID-19 Booster and IIV Schedule in Immunocompromised Hosts
The goal of this pragmatic embedded open-label, 2 x 2 factorial phase II randomized controlled trial is to evaluate strategies to improve COVID-19 booster and influenza vaccine immunogenicity in people living with…
- Conditions
- COVID 19, Influenza, Rheumatoid Arthritis (RA), Systemic Lupus Erthematosus
- Trial name
- CO2I2 (NCT06599658)
- Testing
- Inactivated influenza vaccine (IIV) at baseline, COVID-19 Vaccines at a 3-month interval, Inactivated influenza vaccine at Month 1
- Where
- 3 sites in Canada
- Volunteers
- 660 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Quality of Life, Intensive Care Unit Syndrome
Patients´ Mental and Physical Health After Covid-19 Treated in ICU in Sweden
Covid-19 is a disease where both clinical experience and thus knowledge about the long-term effects of the disease are currently sparse.
- Trial name
- NCT06042790
- Where
- Sweden
- Volunteers
- 2,500 people
- Sponsor
- Swedish Intensive Care Registry
COVID-19
Evaluating the Safety and Efficacy of AD17002 Intranasal Spray in Treating Participants With Mild to Moderate COVID-19
AD17002 enhances nasal mucosal innate immunity and has met safety and efficacy endpoints in studies of nasal adjuvants or intranasal immunomodulators.
- Trial name
- NCT05541510
- Testing
- AD17002 + Formulation buffer
- Where
- 3 sites in Indonesia
- Volunteers
- 180 people
- Sponsor
- Advagene Biopharma Co. Ltd.
Post-COVID-19 Syndrome
Impact Of Sensory Re-Education Paradigm On Sensation And Quality Of Life In Patients Post-Covid 19 Polyneuropathy
This study will be conducted to investigate the effect of a sensory re-education paradigm on sensation and proprioception in patients with post covid-19 neuropathy.
- Trial name
- COVID (NCT05911113)
- Testing
- sensory re-education training, traditional treatment
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
COVID - 19
Open Label Study to Compare Efficacy, Safety and Tolerability of Hydroxychloroquine Combined With Azithromycin Compared to Hydroxychloroquine Combined With Camostat Mesylate and to "no Treatment" in SARS CoV 2 Virus
Patients with COVID-19 which are 60 years old or above or with comorbidities are at risk of deteriorating and developing severe illness.
- Trial name
- COSTA (NCT04355052)
- Testing
- hydroxychloroquine in combination with camostat mesylate, Hydroxychloroquine in combination of Azithromycin
- Where
- 2 sites in Israel
- Volunteers
- 250 people
- Sponsor
- Sheba Medical Center
COVID 19, Depression
COVID-19 : Stress Within Hospital Workers
As of December 2019, the global pandemic of COVID-19 has spread rapidly throughout the world, putting healthcare staff at the frontline.
- Conditions
- COVID 19, Depression, Stress, Psychological, Burnout
- Trial name
- NCT05037214
- Where
- France
- Volunteers
- 779 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Coronavirus, COVID-19
A Study of COVID 19 Convalescent Plasma in High Risk Patients With COVID 19 Infection
Purpose of Study The purpose of this study to evaluate, the effectiveness of convalescent plasma in combatting the symptoms and effects of the coronavirus disease, COVID-19.
- Conditions
- Coronavirus, COVID-19, Convalescent Plasma
- Trial name
- NCT04392232
- Testing
- Convalescent Plasma
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Long COVID-19 Syndrome, COVID 19
Evaluating the Impact of a Functional and Cognitive Strategy in Patients With Long Covid-19
This study aims to evaluate the impact of a functional and cognitive rehabilitation strategy compared to evidence-based informational messages, on functional capacity, cognitive abilities, quality of life, and disease progression…
- Conditions
- Long COVID-19 Syndrome, COVID 19, Noncommunicable Disease, Hypertension
- Trial name
- NCT06871293
- Testing
- Functional and cognitive rehabilitation strategy, Evidence-Based Informational Support
- Where
- Colombia
- Volunteers
- 374 people
- Sponsor
- Fundación Cardioinfantil Instituto de Cardiología
Corona Virus Infection
Restoring Non-Emergent Cardiovascular Care in the Peri- COVID-19 Era
Pre-procedure and Short-Term COVID-19 Testing of Outpatients Undergoing Non-emergent Invasive Cardiovascular Procedures
- Trial name
- RECIPE (NCT04636021)
- Testing
- COVID-19 testing
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Pinnacle Health Cardiovascular Institute
COVID-19, Coronavirus Infection
A Study of Hydroxychloroquine, Vitamin C, Vitamin D, and Zinc for the Prevention of COVID-19 Infection
This is a Phase II interventional study testing whether treatment with hydroxychloroquine, Vitamin C, Vitamin D, and Zinc can prevent symptoms of COVID-19
- Conditions
- COVID-19, Coronavirus Infection, Sars-CoV2, Corona Virus Infection
- Trial name
- HELPCOVID-19 (NCT04335084)
- Testing
- Hydroxychloroquine, Vitamin C, Vitamin D
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
SARS-CoV Infection, Acute Respiratory Distress Syndrome
Glenzocimab in SARS-Cov-2 Acute Respiratory DistrEss syNdrome Related to COVID-19
A randomized, double blind, multicenter, placebo-controlled, parallel group, fixed dose, phase II study to evaluate the efficacy and safety of glenzocimab in ARDS.
- Conditions
- SARS-CoV Infection, Acute Respiratory Distress Syndrome, COVID-19, ARDS
- Trial name
- GARDEN (NCT04659109)
- Testing
- glenzocimab
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Acticor Biotech
Covid19, Corona Virus Infection
Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDS
The world is currently experiencing a coronavirus (CoV-2) pandemic. A new (SARS)-CoV infection epidemic began in Wuhan, Hubei, China, in late 2019; originally called 2019- nCoV the virus is now known as SARSCoV- 2 and the disease…
- Conditions
- Covid19, Corona Virus Infection, ARDS, Aviptadil
- Trial name
- NCT04536350
- Testing
- Aviptadil 67μg
- Where
- 2 sites in Switzerland
- Volunteers
- 83 people
- Sponsor
- Prof. Dr. Jörg Leuppi