Clinical trials: Coronavirus Disease-2019
Corona Virus Disease 2019,COVID-19
Tetrandrine Tablets Used in the Treatment of COVID-19
The study is expected to treat patients with mild and severe neo-coronary pneumonia through standard treatment regimens in combination with tetrandrine tablets, thereby reducing the clinical progress of some patients, improving…
- Trial name
- TT-NPC (NCT04308317)
- Testing
- Tetrandrine
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Henan Provincial People's Hospital
COVID, Coronavirus
The COVID-19 Disease and CARdiac Events Study
An observational study of consecutive patients testing positive for COVID-19 who require admission to hospital to determine the degree of myocardial injury through biomarkers and echocardiography and the impact of this on…
- Trial name
- COVICARE (NCT04438993)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- NHS Lanarkshire
Coronavirus Disease 2019
Autoimmunity Contributes to the Severe Progression of COVID-19
Although elderliness and chronic comorbidities such as hypertension, diabetes, cardiovascular diseases and respiratory diseases, are known risk factors for severe progression of COVID-19, it still remains puzzling on why younger…
- Trial name
- NCT04967781
- Testing
- autoimmunity
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Zhongnan Hospital
COVID-19
Favipiravir Combined With Tocilizumab in the Treatment of Corona Virus Disease 2019
The purpose of this study is to evaluate the efficacy and safety of favipiravir combined with tocilizumab in the treatment of corona virus disease 2019.
- Trial name
- NCT04310228
- Testing
- Favipiravir Combined With Tocilizumab, Favipiravir, Tocilizumab
- Where
- 6 sites in China
- Volunteers
- 150 people
- Sponsor
- Peking University First Hospital
COVID 19
Post Exposure Prophylaxis in Healthcare Workers Exposed to COVID-19 Patients
More cases of COVID-19 pandemic are being reported daily around the world. It is highly infectious and, over 7 million people have been infected and more than 400,000 people have died globally till this date.
- Trial name
- HCQ-COVID19 (NCT04437693)
- Testing
- Hydroxychloroquine
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
COVID-19
A Phase 2 Trial of Infliximab in Coronavirus Disease 2019 (COVID-19).
The investigators hypothesize that early institution of TNFα inhibitor therapy in patients with severe COVID-19 infections will prevent further clinical deterioration and reduce the need for advanced cardiorespiratory support and…
- Trial name
- NCT04425538
- Testing
- Infliximab
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Tufts Medical Center
COVID-19
Efficacy and Safety of Anluohuaxian in the Treatment of Rehabilitation Patients With Corona Virus Disease 2019
To evaluate the efficacy and safety of Anluohuaxian in blocking the progression of pulmonary fibrosis and improving lung function in patients with COVID-19.
- Trial name
- NCT04334265
- Testing
- Anluohuaxian
- Where
- 9 sites in China
- Volunteers
- 750 people
- Sponsor
- Peking University First Hospital
Coronavirus Disease (COVID-19)
Aerosol Transmission of Severe Acute Respiratory Syndrome Coronavirus of Coronavirus Disease 2019
There is little information on the characteristics of airborne severe acute respiratory syndrome coronavirus containing aerosols, their concentration, or their infectivity.The aim was to determine airborne severe acute…
- Trial name
- COVID-19 (NCT04609774)
- Testing
- Severe Acute Respiratory Syndrome CoronaVirus 2 detection
- Where
- Argentina
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Pneumonia, Ventilator-Associated, Coronavirus Infection
Convalescent Antibodies Infusion in Critically Ill COVID 19 Patients
The 2019 outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or COVID 19), which originated in Wuhan, China, has become a major concern all over the world.
- Trial name
- NCT04346589
- Testing
- Anti-coronavirus antibodies (immunoglobulins)obtained with DFPP from convalescent patients
- Where
- 5 sites in Italy
- Volunteers
- 9 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Covid-19
Correlation of Antibody Response to COVID-19 Vaccination in Pregnant Woman and Transplacental Passage Into Cord Blood.
The goal of this study is to study the correlation of maternal and cord blood level of Anti SAR-CoV.
- Trial name
- NCT06259656
- Testing
- COVID-19 Spike Protein IgG Quantitative Antibody (CMIA)
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vachira Phuket Hospital
COVID-19, Coronavirus Disease 2019
A Study to Look at the Health Outcomes of Patients With COVID-19 and Influenza
The main purpose of this study is to understand: the symptoms of COVID-19 or influenza- health-related outcomes of people with COVID-19 or influenza (influenza only included in updated study analyses) the potential effects of…
- Conditions
- COVID-19, Coronavirus Disease 2019, Influenza
- Trial name
- NCT05160636
- Testing
- COVID-19 Vaccine
- Where
- United States
- Volunteers
- 999 people
- Sponsor
- Pfizer
2019 Novel Coronavirus Disease, 2019 Novel Coronavirus Infection
Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 Patients
This study is designed to test the efficacy and safety of combinations of two well-understood agents - famotidine and celecoxib.
- Conditions
- 2019 Novel Coronavirus Disease, 2019 Novel Coronavirus Infection, 2019-nCoV Disease, 2019-nCoV Infection
- Trial name
- NCT05077969
- Testing
- Famotidine, Celecoxib
- Where
- 15 sites in United States
- Volunteers
- 4 people
- Sponsor
- Leidos Life Sciences
COVID-19, Pneumonia, Viral
Checkpoint Blockade in COVID-19 Pandemic
This is a prospective, multicenter, randomized, controlled, open-label, phase 2 clinical trial
- Trial name
- COPERNICO (NCT04335305)
- Testing
- Tocilizumab, Pembrolizumab (MK-3475)
- Where
- 7 sites in Spain
- Volunteers
- 12 people
- Sponsor
- MedSIR
Coronavirus Disease 2019
Clinical Trials of the Consistency and Non-inferiority Bridging Between Batches of Recombinant New Coronavirus Vaccine (CHO Cells)
Popular topic:Clinical trials of the consistency and non-inferiority bridging between batches of recombinant new coronavirus vaccine (CHO cells) Research purpose:Main purpose:1)To evaluate the interbatch consistency of…
- Trial name
- NCT05091411
- Testing
- Recombinant new coronavirus vaccine (CHO cell) group
- Where
- China
- Volunteers
- 1,680 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Covid19
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB-DXP593 in Participants With Mild-to-Moderate Coronavirus Disease 2019 (COVID-19)
The primary objective of this study is to evaluate the efficacy of BGB-DXP593 administered intravenously as a single dose in participants with mild to moderate COVID-19
- Trial name
- NCT04551898
- Testing
- BGB-DXP593
- Where
- 18 sites in United States, Brazil and 2 more
- Volunteers
- 181 people
- Sponsor
- BeiGene
COVID-19, Critical Illness
Recovery of Patients From COVID-19 After Critical Illness
Patients who are critically ill with COVID-19 requiring life support in an intensive care unit (ICU) have increased risk of morbidity and mortality.
- Trial name
- NCT04401254
- Where
- 29 sites in Australia
- Volunteers
- 536 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Covid19, Multiple Sclerosis
COVID-19 and Multiple Sclerosis Disease Modifying Therapies
The COVID-19 pandemic is a major concern for people on long-term treatments that modify the immune system function. People with multiple sclerosis (pwMS) form a large group who receive such treatments called disease modifying…
- Trial name
- NCT04863586
- Where
- United Kingdom
- Volunteers
- 14,240 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Neoplasms, Coronavirus
ASCO Survey on COVID-19 in Oncology (ASCO) Registry
The American Society of Clinical Oncology (ASCO) Survey on Coronavirus 2019 (COVID-19) in Oncology Registry (ASCO Registry) aims to help the cancer community learn more about the patterns of symptoms and severity of COVID-19…
- Trial name
- NCT04659135
- Where
- 77 sites in United States
- Volunteers
- 7,000 people
- Sponsor
- American Society of Clinical Oncology
Covid19, Distress, Emotional
The Practice of Providing Palliative Care in the Situation of the COVID-19 (Coronavirus Disease 2019) Pandemic in Czech Republic
Pandemic of coronavirus SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus 2) causing the disease COVID-19 (Coronavirus Disease 2019) overwhelmed healthcare and brought new challenges and stressful situations.
- Trial name
- PEOpLe-C19 (NCT04910243)
- Testing
- Questionnaire Survey
- Where
- Czechia
- Volunteers
- 307 people
- Sponsor
- Brno University Hospital
Coronavirus Disease 2019 (COVID-19)
A Randomized, Open-label, Dose-ranging Study in Adults and Pediatric Individuals ≥ 12 Years of Age to Assess the Safety, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of AZD7442, for Pre-exposure Prophylaxis of COVID-19
A Phase II Randomized, Open-label, Multicenter, Dose-ranging Study in Adults and Pediatric Individuals ≥ 12 years of Age to Assess the Safety, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of AZD7442, a Combination…
- Trial name
- ENDURE (NCT05375760)
- Testing
- AZD7442 (tixagevimab [AZD8895] + cilgavimab [AZD1061])
- Where
- 16 sites in United States
- Volunteers
- 251 people
- Sponsor
- AstraZeneca