Clinical trials: Coronavirus Sars-Associated
Sars-CoV-2 Infection, Lung Fibrosis
Low-field Magnetic Resonance Imaging of Pediatric COVID-19
SARS-CoV-2 (Severe acute respiratory syndrome coronavirus type 2) is a new coronavirus and identified causative agent of COVID-19 disease. They predominantly cause mild colds but can sometimes cause severe pneumonia.
- Conditions
- Sars-CoV-2 Infection, Lung Fibrosis, Covid19
- Trial name
- DECRYPT (NCT04990531)
- Testing
- Low-field magnetic resonance imaging, Blood sample
- Where
- Germany
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Covid19
Prolonged Symptoms and Reasons for Consultation in Town Medicine Associated With COVID-19 Infection in the Hauts de France Region
Several publications document the occurrence of prolonged or late-onset symptoms beyond 3 weeks after the first clinical manifestations of SARS-COV2 infection.
- Trial name
- COCO_Vi_LATE (NCT04817293)
- Testing
- Questionnaire, medical consultation
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tourcoing Hospital
Coronavirus Infection, COVID-19
Clinical Study of the Safety and Immunogenicity of a Recombinant Viral Vector AAV5 (Adeno-Associated Virus Type 5 )-RBD (Receptor Binding Domain)-S Vaccine for the Prevention of Coronavirus Infection (COVID-19)
A randomized, double-blind, placebo-controlled, adaptive, seamless phase I / II clinical study of the safety and immunogenicity of a recombinant viral vector AAV5-RBD-S vaccine for the prevention of coronavirus infection…
- Trial name
- COVER (NCT05037188)
- Testing
- Low dose BCD-250 injection, High dose BCD-250 injection, Low dose or high dose BCD-250 injection
- Where
- 2 sites in Russia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Biocad
Covid19
Study of Socio-demographic Factors, Behaviors and Practices Associated With Infection With SARS-CoV-2 Responsible for COVID-19
The objective of the study is to identify socio-demographic factors, behaviors and practices associated with infection with SARS-CoV-2 to help determine where and how patients mostly get infected with SARS-CoV-2.
- Trial name
- ComCor (NCT04607941)
- Testing
- Questionnaires, Phone interviews
- Where
- 2 sites in France
- Volunteers
- 766,818 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
COVID-19 Stress Syndrome, COVID-19 Vaccine Adverse Reaction
COVID-19 Vaccination Detoxification in LDL-C
The study hypothesizes that SARS-CoV-2 vaccination poisoning hibernates in human host in Low Density Lipoprotein Cholesterol (LDL-C). The clinical trial is a follow-up from the intervention trial with NCT number NCT05711810.
- Conditions
- COVID-19 Stress Syndrome, COVID-19 Vaccine Adverse Reaction, COVID-19-Associated Thromboembolism, COVID-19 Post-Intensive Care Syndrome
- Trial name
- NCT05839236
- Testing
- Atorvastatin Calcium Tablets
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Yang I. Pachankis
Pulmonary Complications, Cardiovascular Complications
The Incidence of Pulmonary, Cardiovascular and Renal System Non-communicable Complications Associated With the Post-acute Phase of the Infection by Covid-19
More than 660 million cases of COVID-19 have been reported worldwide, with 183 million cases in the EU alone. In several people, after recovery, the effects of the first waves of COVID-19 persisted beyond the acute phase and…
- Conditions
- Pulmonary Complications, Cardiovascular Complications, Renal Complications, COVID-19
- Trial name
- POINT (NCT06608849)
- Testing
- Blood samples, Six-minute walk test, Spirometry, HRCT, Heart ultrasound, Completion of questionnaires of symptoms
- Where
- 6 sites in Greece
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Hellenic Institute for the Study of Sepsis
Anxiety Related to the COVID-19 Pandemic
Survey of the Anxiety Associated With the COVID-19 Pandemic
The study aims to systematically examine various aspects of the anxiety associated with the COVID-19 pandemic in Germany. The data collection is carried out online with longitudinal repeated measurements.
- Trial name
- CORA (NCT04331106)
- Testing
- Online Questionnaire
- Where
- Germany
- Volunteers
- 7,500 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Patients Post-COVID-19, Controls
Sequelae of COVID-19 With Focus on Exercise Capacity and Underlying Mechanisms
The project is designed as a cross-sectional study and aims to examine long-term consequences of coronavirus disease 2019 (COVID-19) for selected bio-behavioural parameters while taking the disease course severity into account.
- Trial name
- COR-PHYS (NCT05118711)
- Testing
- Cardiorespiratory fitness, Lung function, Muscular strength and balance tests
- Where
- Switzerland
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Arno Schmidt-Trucksäss
Covid19
Description of Immunologic, Enzymatic and Metabolic Biomarkers Associated to the Severity of COVID-19 (SARS-CoV-2) and Its Resolution
Prospective study to describe the immunological, metabolic and serologic profile in the acute and post acute phases of Coronavirus disease (COVID-19)
- Trial name
- BIOMARK-COVID (NCT04664023)
- Testing
- Blood collection at Day 8, Day 16, Day 24, Month 6 and Month 12 after first symptoms from SARS-CoV-2 infection., Blood collection at 1st injection of vaccine against COVID-19, at at second injection of vaccine, at Month 1, Month 2, Month 6 and Month 12 after second injection of vaccine for volunteers
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Travel-Related Illness, Malaria
Infection Tracking in Travellers. The Project Aims to Identify Profiles of Travel-associated Illness and to Follow up on Long-term Sequelae of Arboviral Infections and Malaria
The investigators hypothesize that sex, age, area of exposure and purpose of travel are associated with different travel-related infections. The investigators also hypothesize that certain infections will have long-term sequelae.
- Conditions
- Travel-Related Illness, Malaria, Dengue, Chikungunya
- Trial name
- ITIT (NCT04672577)
- Testing
- Observational study
- Where
- Switzerland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Patricia Schlagenhauf
Coronavirus Infection, Severe Acute Respiratory Syndrome
COVID-19 Health Professional Impact Study
The COVID-19 (coronavirus) pandemic has had a huge impact on healthcare resources and staff in the UK. Understanding the key risk factors associated with infection amongst healthcare workers is essential for future pandemic…
- Trial name
- CHIP (NCT04527432)
- Testing
- Survey, SARS-CoV-2 antibody test
- Where
- United Kingdom
- Volunteers
- 1,504 people, healthy volunteers welcome
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Coronavirus Infections, Coronavirus Sars-Associated
Protocol Design for Evaluating the Immunity of Bivalve Fluids From Anodonta Cygnea in SARS and COVID-19
The present work proposes to find if a bio-active composite in the hemolymph or plasma of the freshwater bivalve Anodonta cygnea is able to offer immunity and specificity for meliorating the major symptoms in human SARS and…
- Conditions
- Coronavirus Infections, Coronavirus Sars-Associated, SARS (Severe Acute Respiratory Syndrome), COVID-19
- Trial name
- NCT05054075
- Testing
- Marine liquid and fluids, Impregnation, Incubation
- Where
- 2 sites in Portugal
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
SARS-Associated Coronavirus, Covid19
Treatment of Critically Ill Patients With Covid-19 With Convalescent Plasma
This study aims to collect convalescent plasma and use it as experimental treatment in critically ill Covid-19 patients in order to reduce mortality and length of stay in intensive care unit.
- Conditions
- SARS-Associated Coronavirus, Covid19, SARS-CoV Infection
- Trial name
- NCT04468009
- Testing
- Convalescent plasma
- Where
- Argentina
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Hospital de Infecciosas Francisco Javier Muniz
Covid19, High Altitude
Prevalence of COVID-19 in High Altitude : Insights From the Highest City of the World
Since the beginning of 2020, SARS-CoV-2 outbreak spread over the world, conducting in a pandemic state declared by the world health organization in March 2020.
- Trial name
- RINCOVID (NCT04604249)
- Testing
- SARS-CoV-2 rapid diagnostic test (COVID-PRESTO® IgM/IgG, AAZ, Boulogne-Billancourt, France)
- Where
- Peru
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centre d'Expertise sur l'Altitude EXALT
SARS-CoV-2, BCG
SARS-CoV-2/COVID-19 Infection Among Health Care Workers
The present study finds opportunities and justifications, taking into consideration that the nature of professional practice in health needs scientific evidence resulting from systematic and systemic studies to strengthen the…
- Conditions
- SARS-CoV-2, BCG, Health Care Worker, COVID-19
- Trial name
- NCT04826718
- Testing
- Questionaire
- Where
- Cabo Verde
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Universidade de Cabo Verde
Covid19, MIS-C Associated With COVID-19
Pediatric COVID Outcomes Study (PECOS)
This is a multisite prospective observational study to evaluate the clinical sequelae of symptomatic and asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the pediatric population, including…
- Conditions
- Covid19, MIS-C Associated With COVID-19, MIS-C Multisystem Inflammatory Syndrome in Children, SARS-CoV2 Infection
- Trial name
- NCT04830852
- Where
- 2 sites in United States
- Volunteers
- 1,097 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Covid19, COVID-19 Pneumonia
NAC for Attenuation of COVID-19 Symptomatology
The objective of this study is to determine whether oral NAC is effective at attenuating COVID-19 disease symptom severity and duration of symptoms.
- Conditions
- Covid19, COVID-19 Pneumonia, COVID-19 Respiratory Infection, COVID-19 Lower Respiratory Infection
- Trial name
- NACinCOVID2 (NCT05074121)
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
COVID, Sars-CoV2
Efficacy of N-Acetylcysteine (NAC) in Preventing COVID-19 From Progressing to Severe Disease
The purpose of this study is to assess the efficacy of N-acetylcysteine (NAC) in preventing those with mild or moderate COVID-19 from progressing to severe disease
- Conditions
- COVID, Sars-CoV2, SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere, Oxidative Stress
- Trial name
- NCT04419025
- Testing
- N-acetylcysteine
- Where
- 4 sites in United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
COVID-19, Pneumonia, Viral
Effectiveness of Covid-19 Vaccination in Eswatini Against SARS-CoV-2 Associated Hospitalization and Death
Since late December 2019, the novel human coronavirus (SARS-CoV-2) first reported in China, has spread worldwide. Vaccines to prevent SARS-CoV-2 infections have been developed in record time and several candidate vaccines have…
- Trial name
- NCT04914832
- Testing
- AZD1222
- Where
- Eswatini
- Volunteers
- 75,012 people, healthy volunteers welcome
- Sponsor
- Shabir Madhi
COVID-19
Efficacy of Breathox Device Inhalation Therapy in the Treatment of Acute Symptoms Associated With COVID-19 and in the Prevention of the Use of Health Resources
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), the new coronavirus, causes a disease called COVID-19 that can trigger aggressive inflammatory responses.
- Trial name
- BREATH (NCT05196581)
- Testing
- Dispersible NaCl powder 10 sessions, Dispersible NaCl powder 5 sessions
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Suzana Erico Tanni Minamoto