Clinical trials: Cortisol
Sepsis, Septic Shock
Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis
Prospective, experimental, longitudinal cohort study in septic patients treated at ER and ICU at General Hospital Zone 11 IMSS Piedras Negras Coahuila.
- Trial name
- NCT04197115
- Testing
- Vitamin C, Hydrocortisone, Complex B
- Where
- Mexico
- Volunteers
- 19 people
- Sponsor
- IMSS Hospital General de Zona 11, Piedras Negras
Family Resilience, Parent-Infant Bonding
Development and Evaluation of an Intelligent Parent-Infant Connection-Based Intervention to Strengthen Family Resilience in Preterm Infant Care
This study aims to develop, optimize, and evaluate the effectiveness of a family resilience intervention centered on intelligent parent-infant connection for parents of preterm infants.
- Conditions
- Family Resilience, Parent-Infant Bonding, Parents of Premature Infants, Intelligent Intervention
- Trial name
- NCT07373002
- Testing
- Intelligent Intervention to enhance Parent-Infant Connection and Family Resilience, Routine Care
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Healthy
Rapid Effects of Hydrocortisone on Glucose-induced Insulin Secretion in Healthy Humans
The purpose of this study is to investigate the effect of hydrocortisone on glucose-induced insulin secretion and sensitivity, by means of an intravenous glucose tolerance test with frequent sampling (FSIGT) followed by minimal…
- Trial name
- NCT00709839
- Testing
- Hydrocortisone, Glucose 33%
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Cushing Syndrome, Adrenal Insufficiency
Clinical Study on Circadian Genes Dysregulation in Patients With Glucocorticoid Disorders
This is a multicentric, prospective, intervention study on circadian genes expression in peripheral blood mononuclear cells as biomarkers of circadian rhythm derangement in patients affected by alterations of endogenous…
- Conditions
- Cushing Syndrome, Adrenal Insufficiency, Cushing Disease, Addison Disease
- Trial name
- CHROnOS (NCT04374721)
- Testing
- circadian gene expression evaluation
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Depression
Genetic and Biochemical Markers of Interferon-Induced Depression.
The purpose of this study is to identify predictors and associated biochemical markers of interferon-induced depression. It is hypothesized that genetic variation in genes related to the serotonergic system may predict…
- Trial name
- NCT00252538
- Where
- 3 sites in United States
- Volunteers
- 133 people
- Sponsor
- US Department of Veterans Affairs
Psychological Stress, Depression - Major Depressive Disorder
The Effect of Mindfulness in Inflammation Markers (IL-6, TNF-A, CRP and Cortisol) Among Survivors of Tidal Flooding in Sayung Demak
Recurrent tidal flooding (rob) in the coastal areas of Sayung District, Demak Regency, poses a continuous environmental threat that inflicts housing damage, economic instability, and prolonged socioeconomic uncertainty on local…
- Conditions
- Psychological Stress, Depression - Major Depressive Disorder, Anxiety, Inflammation
- Trial name
- NCT07790055
- Testing
- Mindfulness Body Scan Training
- Where
- Indonesia
- Volunteers
- 75 people
- Sponsor
- Natalia Dewi Wardani, MD
Mild Autonomous Cortisol Secretion
Ketoconazole Effects on the Daily Cortisol Rhythm in Mild Autonomous Cortisol Secretion
Background: Cortisol is a hormone in the blood. Cortisol levels normally go down at night and up in the morning. Mild autonomous cortisol secretion (MACS) is a disease in which the body makes too much cortisol.
- Trial name
- NCT07649317
- Testing
- Ketoconazole
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Sleep
Kavalactones on Sleep and Cortisol in Healthy Special Forces Trainees
This research study is being done to better understand the effects of kava supplementation on sleep quality and salivary cortisol in the context of the acute physical and psychological stress of military special forces…
- Trial name
- NCT05381025
- Testing
- Kava (Piper methysticum) extract
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Thorne HealthTech, Inc
Stress, Stress (Psychology)
Effect of Magnesium-, Vitamin C- and Grape Seed Extract-Enriched Date Bars on Perceived Stress and Salivary Cortisol Levels in Young Women
This randomized controlled trial aims to evaluate the effect of a 4-week daily consumption of a functional date bar enriched with magnesium, vitamin C, and grape seed extract on perceived stress and salivary cortisol levels in…
- Trial name
- NCT07585422
- Testing
- Functional Bar
- Where
- Russia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- K.G. Razumovsky Moscow State University of Technologies and Management
Pituitary Neoplasms, Craniopharyngiomas
Effect of Perioperative Glucocorticoid Replacement on Prognosis of Surgical Patients With Sellar Lesions
The purpose of this four-arm randomized controlled study is to determine whether eliminating glucocorticoids (GC) replacement in perioperative period in surgical patients with sellar lesion could result in similar or better…
- Trial name
- NCT02190994
- Testing
- Hydrocortisone, Prednisone
- Where
- China
- Volunteers
- 100 people
- Sponsor
- West China Hospital
Neonatal Disorder
Impact of Tactile Kinesthetic Stimulation and Soft Tissue Manipulation on Cortisol in Preterm
Effect of Soft tissue Therapy in managing Procedural Pain among neonates admitted to the neonatal intensive care unit. This study focuses on procedural pain management with the help of Soft tissue manipulation, which includes…
- Trial name
- NCT06845137
- Testing
- Tactile-Kinesthetic Stimulation (TKS) and Soft Tissue Manipulation (STM), Standard Therapy
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- faizan kashoo, PT
Jaw, Edentulous, Partially
The Effect of Immediate Implant Placement and Provisionalization in the Esthetic Zone
The purpose of this study is to compare two different techniques of placing dental implants: 1) removing the tooth and placing the implant immediately and 2) removing the tooth and placing both the implant and a temporary crown…
- Trial name
- 3i (NCT02021331)
- Testing
- immediate implant placement without provisionalization, immediate implant placement with immediate provisionalization
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Oxidative Stress, Aging
Stress Resilience Study
The purpose of this study is to test the hypothesis that physiological adaptations to regular exercise training (i.e. physical fitness) attenuates age-related decline in stress resilience to both oxidative stress and the…
- Trial name
- NCT00891488
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kronos Longevity Research Institute
Postpartum Depression (PPD)
Moringa Oleifera and Phoenix Dactylifera L. Effects on Cortisol and Breast Milk in Postpartum Depression
Postpartum depression affects 10-20% of new mothers globally, potentially disrupting breast milk production. This study aimed to provide valuable insights into effective interventions to improve the health and well-being of…
- Trial name
- NCT07337512
- Testing
- Phoenix dactylifera L, Moringa oleifera
- Where
- Indonesia
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- Melania Asi
Postoperative Pain, Cesarean Section
Effect of a Transversus Abdominis Plane Block on Wound Healing, Stress, and Immune Response After a Cesarean Delivery
The primary purpose of this study is to determine whether the addition of a TAP block to standard analgesia after the cesarean delivery will impact postoperative wound healing and attenuate postoperative stress and immune…
- Conditions
- Postoperative Pain, Cesarean Section, Wound Heal
- Trial name
- NCT05840406
- Testing
- Postoperative pain management with acetaminophen, Bilateral TAP Block with levobupivacaine, Bilateral TAP Block with levobupivacaine and dexmedetomidine
- Where
- Croatia
- Volunteers
- 105 people
- Sponsor
- University Hospital Sestre Milosrdnice
Infant, Premature Birth
Massage Application and Motor Performance, Stress Assessment in Premature Babies
In our study, the effect of infant massage applied in the intensive care unit on motor performance and stress hormones in premature babies will be examined. The number of patients to participate in the study was determined as 30.
- Trial name
- NCT06075992
- Testing
- experimental group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Mustafa Kemal University
Septic Shock
Activated Protein C and Corticosteroids for Human Septic Shock
This study aims at comparing the efficacy and safety of recombinant human activated protein C to that of low dose of corticosteroids and at investigating the interaction between these drugs in the management of septic shock
- Trial name
- APROCCHS (NCT00625209)
- Testing
- recombinant human activated protein C and hydrocortisone and fludrocortisone
- Where
- 4 sites in France
- Volunteers
- 1,241 people
- Sponsor
- University of Versailles
Prostate Cancer
The Effect of Intrarectal Ice Application on Pain, Anxiety, Cortisol Level, Complication Development in Transrectal Ultrasonography Guided Prostate Biopsy
Transrectal ultrasound (TRUS)-guided prostate biopsy is one of the most commonly performed urological procedures today. This technique involves the insertion of a needle through the rectal mucosa to access the prostate.
- Trial name
- NCT06998121
- Testing
- Intrarectal ıce application
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Mersin University
Esophageal Stenosis Acquired
Mixed Gel of Hydrocortisone and Aluminium Phosphate Preventing Endoscopic Submucosal Dissection Postoperative Stenosis for Patients With Large Esophageal Carcinoma
Endoscopic submucosal dissection as the fastest growing endoscopic treatment technology in the past decade has been widely used in the treatment of early esophageal cancer and gastric cancer without local lymph node metastasis.
- Trial name
- NCT03165344
- Testing
- Hydrocortisone sodium succinate mixed with Aluminium Phosphate gel (route of administration), Triamcinolone Acetonide (route of administration), Prednisone (route of administration)
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Peking University Third Hospital
Shock, Septic
Effects of Hydrocortison Treatment on Angiotensin II and Angiotensin II Receptors in Patients With Septic Shock
This study aims to evaluate the role of angiotensin II, AT1, and AT2 on catecholomine responsive and catecholomine resistant septic shock, and the effect of hydrocortisone traetment on catecholomine resistant septic shock and…
- Trial name
- NCT04647552
- Testing
- Drug Steroid
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Inonu University
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