Clinical trials: Cortisol
Diabetes, Stroke
Testing the Developmental Origins Hypothesis
INTRODUCTION: CHIPS-Child is a parallel, ancillary study to the CHIPS randomized controlled trial (RCT). CHIPS is designed to determine whether 'less tight' control [target diastolic BP (dBP) 100mmHg] or 'tight' control [target…
- Conditions
- Diabetes, Stroke, Obesity
- Trial name
- CHIPS-Child (NCT01545492)
- Where
- 41 sites in United States, Australia and 6 more
- Volunteers
- 626 people
- Sponsor
- Children's & Women's Health Centre of British Columbia
Interleukin-6, Cortisol
Effectivity of Bilateral Transversus Thoracis Muscle Plane Block After Open Heart Surgery
This Study aimed to assess The Effectivity of Bilateral Transversus Thoracis Muscle Plane Block to Reduce Pain and Stress Response After Open Heart Surgery
- Trial name
- NCT04544254
- Testing
- Bilateral transversus thoracis muscle plane block, Control
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Acute Myocardial Infarction
Hair Cortisol and Testosterone Levels in Patients With and Without Acute Myocardial Infarction(MI)
The purpose of this study is to determine whether hair levels of cortisol and testosterone are elevated in patients with acute MI compared to controls.
- Trial name
- NCT01144065
- Testing
- Hair sampling for the measurement of cortisol and testosterone
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Meir Medical Center
Septic Shock, Sepsis
Stress Doses of Hydrocortisone on Coagulation Dysfunction in Patients With Septic Shock
The purpose of this study is to find out whether stress doses of hydrocortisone attenuate coagulation dysfunction in patients with septic shock.
- Trial name
- NCT02266589
- Testing
- Hydrocortisone
- Volunteers
- 84 people
- Sponsor
- Nanjing PLA General Hospital
Hormonal Response, Mineral Metabolism
Effects of Chronic Exercise on Hormonal and Mineral Biomarkers in Male University Students
The purpose of this study is to investigate the effects of a high-intensity interval training (HIIT) program on hormonal and mineral biomarkers and aerobic fitness in male university students.
- Conditions
- Hormonal Response, Mineral Metabolism, Exercise Training
- Trial name
- NCT07893613
- Testing
- High-intensity interval training program
- Where
- Tunisia
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- High Institute of Sports and Physical Education of Kef
Parkinson's Disease, Coping Skills
Expressive Writing for Individuals With Parkinson's Disease and Their Caregivers
This randomized, controlled trial (RCT) evaluates the benefits of expressive compared to neutral writing in individuals with Parkinson's Disease and their support persons.
- Trial name
- PDEWS (NCT02217735)
- Testing
- Writing Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Virginia Commonwealth University
Impacted Third Molar Tooth
Topical Hydrocortisone for Pain and Edema Control After Third Molar Surgery
The investigators set out to develop a clinical trial in order to test the topical use of hydrocortisone as a intraoperative irrigant solution.
- Trial name
- NCT03179813
- Testing
- Hydrocortisone, Control
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cognitive Assessment, Working Memory
Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure.
The proposed project will evaluate the synergistic effects of a nutritional formulation, 'Think Tank' on cognitive performance following exposure to a psychological and physical stressor.
- Conditions
- Cognitive Assessment, Working Memory, Executive Function (Cognition), Sustained Attention
- Trial name
- NCT07319117
- Testing
- Skoshify 'Think Tank' Formulation
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Liver Cirrhosis
Supplemental Corticosteroids in Cirrhotic Hypotensive Patients With Suspicion of Sepsis
The main goal of the study is to investigate the clinical relevance, efficacy and safety of treating hypotensive cirrhotic patients with suspicion of sepsis and on vasopressors with low-dose hydrocortisone in order to reverse…
- Trial name
- SCOTCH; (NCT02602210)
- Testing
- Hydrocortisone, NaCL 0.9%
- Where
- 10 sites in Belgium, Czechia and 5 more
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Psychological Distress
The Psychological Effect of the Covid-19 Pandemic
At the end of 2019, the novel coronavirus disease (Covid-19), which emerged in China, has become a public health emergency of international concern.
- Trial name
- NCT05503589
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Dental Implant in Compromised Adjacent Sockets
Soft Tissue Stability in the Esthetic Zone: A Randomized Clinical Trial Comparing Vestibular Socket Therapy With Contour Augmentation for Compromised Adjacent Sockets
While early implant placement with guided bone regeneration (GBR) offers advantages, the desire for reduced treatment time and fewer surgical steps continues to drive the exploration of alternative approaches.
- Trial name
- NCT06673446
- Testing
- vestibular socket therapy
- Where
- Egypt
- Volunteers
- healthy volunteers welcome
- Sponsor
- British University In Egypt
Postresuscitation Syndrome
HYdrocortisone and VAsopressin in Post-RESuscitation Syndrome
The primary objective is to demonstrate the superiority of arginine-vasopressin (AVP) and hydrocortisone compared with norepinephrine regarding day-30 survival and neurological recovery in post-cardiac arrest patients with…
- Trial name
- HYVAPRESS (NCT04591990)
- Testing
- Administration of AVP, Administration of hydrocortisone
- Where
- 14 sites in France
- Volunteers
- 380 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pregnancy Related, Cannabis Use
Effects of Pregnancy-associated Hormones on THC Metabolism in Women
Cannabis use is prevalent among pregnant women, but the effects of use on both the developing fetus and pregnant woman are unknown.
- Trial name
- PrECEPT (NCT04374773)
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dental Fear and Anxiety
Assessing the Efficacy of Lemongrass and Lavender Aromatherapy in Reducing Dental Anxiety and Pain Associated With Local Anesthetic Injections in Pediatric Dental Patients
The goal of this clinical trial is to evaluate whether aromatherapy using lemongrass or lavender essential oils can reduce dental anxiety and pain perception in children aged 7-11 years undergoing local anesthetic administration…
- Trial name
- NCT07113080
- Testing
- lavender essential oil inhaled using face mask, lemongrass essential oil inhaled using face mask
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hiba Ahmed Eltayeb
Dental Caries
Impact of Atraumatic Restorative Treatment and Oral Health Promotion on Psychological and Salivary Aspects of Children
This study evaluated the impact of atraumatic restorative treatment associated with oral health educational strategy on dental anxiety, oral health-related quality of life and salivary biochemical and microbiological…
- Trial name
- NCT03100773
- Testing
- Oral health educational strategy, Atraumatic Restorative Treatment
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Congenital Adrenal Hyperplasia
Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia
This study is a randomized, double-blind, active-controlled, phase III study of Chronocort® compared with immediate-release hydrocortisone replacement therapy in participants aged 16 years and over with Congenital Adrenal…
- Trial name
- CONnECT (NCT05063994)
- Testing
- Chronocort, Cortef
- Where
- 21 sites in United States, France and 1 more
- Volunteers
- 55 people
- Sponsor
- Neurocrine UK Limited
Obesity
Longitudinal Study of the Psychological Impact of Bariatric Surgery
This prospective observational study evaluates the effect of bariatric surgery on mental health and hair cortisol in patients with morbid obesity over a 3-year follow-up.
- Trial name
- BARI-SCL (NCT07780058)
- Where
- 2 sites in Spain
- Volunteers
- 70 people
- Sponsor
- University of Alicante
Alcohol Abuse, Craving
Using Neurofeedback to Understand the Relationship Between Stress and Alcohol Consumption
In this research project, the aim is to discover the role specific brain networks play in the relationship between stress reactions and the desire for alcohol and alcohol consumption.
- Conditions
- Alcohol Abuse, Craving, Psychosocial Stressor, Neural Stress Response
- Trial name
- NeuStress (NCT06247306)
- Testing
- ScanSTRESS fMRI-paradigm (Streit et al., 2014), real-time fMRI neurofeedback
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Allergic Conjunctivitis
Hydrocortisone Ophthalmic Ointment 0.5% for Treatment of Allergic Conjunctivitis
The purpose of this study is to determine the safety and effectiveness of hydrocortisone ophthalmic ointment compared to placebo in the treatment of Allergic Conjunctivitis.
- Trial name
- NCT01860664
- Testing
- hydrocortisone ophthalmic ointment 0.5%
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Koffler Vision Group
Prader-Willi Syndrome
Cortisol Activity in Patients With Prader-Willi Syndrome and Healthy Controls
The purpose of the study is to find out if people with Prader-Willi syndrome have a difference in the protein which changes inactive cortisone to the active stress hormone cortisol.
- Trial name
- NCT00932932
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
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