Clinical trials: Cosmetic Outcome
Uterine Myoma, Uterine Adenomyosis
Single Incision Laparoscopic Surgery (SILS) Versus Conventional Laparoscopic Hysterectomy
Multi-center prospective randomized trial of single port laparoscopic surgery (SILS) versus conventional 3-4 ports laparoscopic hysterectomy.
- Trial name
- NCT01483417
- Testing
- Single incision Laparoscopic hysterectomy, Conventional laparoscopic hysterectomy
- Where
- 8 sites in South Korea
- Volunteers
- 240 people
- Sponsor
- Samsung Medical Center
Breast Cancer Female
Cosmetic Outcome, Patient-reported Outcomes, and Reconstruction-related Complications in Breast Cancer Women Treated With or Without Post-mastectomy Radiation Therapy
This study aim to investigate the breast reconstruction outcome after mastectomy with or without radiation therapy from the patient's point of view.
- Trial name
- NCT03523078
- Testing
- Breast reconstructive surgery
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Yonsei University
Breast Cancer
RAPID: Randomized Trial of Accelerated Partial Breast Irradiation
To determine if Accelerated Partial Breast Irradiation, using 3D CRT, is as effective as Whole Breast Irradiation following breast conserving surgery in women with an new histological diagnosis of ductal carcinoma in situ only or…
- Trial name
- NCT00282035
- Testing
- APBI utilizing 3D-CRT radiation, Whole breast irradiation
- Where
- 33 sites in Australia, Canada and 1 more
- Volunteers
- 2,135 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Breast Cancer
Patient Registry: Partial Breast Irradiation
This is an Aurora Health Care system registry of patients receiving accelerated partial breast irradiation and external beam.
- Trial name
- PBI Registry (NCT01127971)
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- Wake Forest University Health Sciences
Successful Surgical Procedure, Operative Time
LESS Surgery Versus Conventional Multiport Laparoscopy in Ovarian Drilling
laparoendoscopic single-site surgery is compared to conventional multi-port laparoscopy for polycystic ovary syndrome in infertile women undergoing ovarian drilling as regards successful surgical procedure with less side effects
- Conditions
- Successful Surgical Procedure, Operative Time, Cosmetic Outcome, Intra- and Post- Operative Complications
- Trial name
- NCT03206892
- Testing
- laparoscopic ovarian drilling
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Orbital Implants
A Modified Orbital Implantation Technique in Enucleation
To assess the functional and cosmetic outcomes of enucleation with rectus end-to-end suturing surgical technique in hydroxyapatite orbital implants
- Trial name
- NCT01207713
- Volunteers
- 45 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Papillary Thyroid Carcinoma, Thyroid Cancer
Cross-sectional Case and Control Study on Quality of Life, Appearance and Functions in PTC Via Different Surgical Approach
An observational cross-sectional case-control study on the postoperative quality of life (5 aspects, general quality of life, thyroid specific quality of life, scar appearance, voice and swallowing functions) of papillary thyroid…
- Trial name
- NCT05932121
- Testing
- Thyroid lobectomy via trans-axillary approach, Thyroid lobectomy via open approach
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Breast Cancer
Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients
In this ABLATIVE-2 trial, low-risk breast cancer patients will be treated with MRI-guided single dose preoperative partial breast radiotherapy to assess the rate of pathologic complete response after an interval of six to twelve…
- Trial name
- ABLATIVE-2 (NCT05350722)
- Testing
- Single dose ablative radiotherapy
- Where
- 7 sites in Australia, Netherlands
- Volunteers
- 100 people
- Sponsor
- Amsterdam UMC, location VUmc
Thyroidectomy, Distress
Postoperative Distress and Cosmetic Outcomes After Open Versus Robotic Thyroidectomy
Robotic assistance during thyroid surgery has been utilized clinically in Korea since late 2007. Robotic thyroidectomy has also been validated for surgical management of the thyroid gland.
- Conditions
- Thyroidectomy, Distress, Surgery
- Trial name
- Robot1 (NCT01075269)
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Korean Association of Endocrine Surgeons
Breast Neoplasm Female, Radiotherapy
A Randomized Trial of Five Fraction Partial Breast Irradiation (RAPID2)
The primary objective of this study is to determine in women with node negative BC ≤3cm in size, if PBI compared to WBI, both given once-a-day over 1 week following BCS, is non-inferior for LR and reduces adverse cosmesis.
- Conditions
- Breast Neoplasm Female, Radiotherapy, Cosmetic Outcome
- Trial name
- NCT05417516
- Testing
- Whole Breast Irradiation (WBI), Partial Breast Irradiation (PBI)
- Where
- 31 sites in Australia, Canada
- Volunteers
- 910 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Breast Cancer
Ten Fraction Adjuvant Hypofractionated Radiotherapy in Node Positive Breast Cancer
Post-operative loco-regional (LR) hypofractionated radiotherapy (Hypo-RT) is an attractive approach in locally advanced breast cancer (LABC).
- Trial name
- HIPOMAMMLINF (NCT04792346)
- Testing
- breast/chest wall radiotherapy
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- Regina Elena Cancer Institute
Cosmetic Outcome, Infection
Sutures Versus Glue in Laparoscopic Port Site Closure.
Cosmesis postoperatively is an important consideration for both patients and surgeons and consequently surgeons have become increasingly interested in replacing conventional sutures by means of adhesive bonds for the closure of…
- Conditions
- Cosmetic Outcome, Infection, Cost
- Trial name
- STILS (NCT03843866)
- Testing
- 4-0 Monocryl, Adhesive Glue
- Where
- Ireland
- Volunteers
- 200 people
- Sponsor
- St. James's Hospital, Ireland
Recurrent Breast Carcinoma, Ipsilateral Recurrence
Preoperative Partial Breast Reirradiation and Repeat Breast-conserving Surgery in Patients With Recurrent Breast Cancer: the REPEAT Trial
Over the past decades, interest in second breast-conserving therapy (BCT) has increased due to, among others, advancements in radiotherapy techniques.
- Trial name
- REPEAT (NCT06640881)
- Testing
- ablative single-dose PBI
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Amsterdam UMC, location VUmc
Scar, Skin Scarring
Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
Patients will be randomized either to receive standard daily dressing or hydrocolloid dressing using a randomization generator. After closing the wound with the sutures,the scar will be covered by a hydrocolloid dressing, which…
- Conditions
- Scar, Skin Scarring, Skin Cancer, Wound Heal
- Trial name
- NCT05618912
- Testing
- Hydrocolloid dressing, Petrolatum jelly dressing
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Indiana University
Eyelid Laceration
Cosmetic Outcome Study of Lid Laceration Repair With Suture Versus Tissue Adhesive
This project is a randomized, controlled trial investigating wound cosmetic appearance after repair of traumatic lid lacerations with three different approaches to skin closure: absorbable sutures, non-absorbable sutures, and…
- Trial name
- NCT01918059
- Testing
- Tissue Adhesive skin closure, Absorbable suture skin closure, Non-absorbable suture skin closure
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Breast Image Scale Index for Self Esteem Evaluation, Breast Symmetry Index
Prospective Non-randomized Evaluation of Oncoplastic Surgery
Breast conserving therapy (BCT) is the standard treatment for intraductal or invasive breast cancer patients. However cosmetic results, e.g. symmetry and nipple displacement, are sometimes poor reducing the quality of life.
- Conditions
- Breast Image Scale Index for Self Esteem Evaluation, Breast Symmetry Index, Quality of Life, Morbidity
- Trial name
- iTOP (NCT01396993)
- Testing
- Breast Surgery
- Where
- Austria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Wound Complication, Surgical Wound Infection
Electrocautery Versus Scalpel for Skin Incisions
The aim of this research project is to compare electrocautery to scalpel for laparotomy skin incisions, with the following objectives: 1. To investigate whether electrocautery produces a cosmetically inferior surgical scar. 2.
- Conditions
- Wound Complication, Surgical Wound Infection, Post-operative Pain
- Trial name
- NCT01496404
- Testing
- Electrocautery, Scalpel
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- St. Paul's Hospital, Canada
Bowen's Disease
Trial of Excision Versus Photodynamic Therapy in the Treatment of Bowen's Disease
The purpose of this study is to identify the most optimal therapy for Bowen's disease: excision versus Photodynamic therapy.
- Trial name
- NCT00472706
- Testing
- excision, Photodynamic therapy
- Volunteers
- 65 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Breast Cancer
Use of the Contura™ Catheter to Deliver Accelerated Partial Breast Irradiation to "Low-risk" Breast Cancer Patients
The purpose of this national, multi-site study is to determine the safety and effectiveness of the Contura catheter in breast cancer patients undergoing accelerated partial breast irradiation.
- Trial name
- NCT00882596
- Testing
- Accelerated partial breast irradiation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cancer Center of Irvine
Seroma
The QUILT Study: Quilting Sutures in Patients Undergoing Breast Cancer Surgery
Seroma is the most common complication following breast cancer surgery, with reported incidence up to 90%. Seroma causes patient discomfort, is associated with surgical site infections (SSI), often requires treatment and…
- Trial name
- QUILT (NCT05272904)
- Testing
- Quilting, Conventional wound closure
- Where
- Netherlands
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Canisius-Wilhelmina Hospital