Clinical trials: Cost Benefit Analysis
Prescriptions, Costs and Cost Analysis
Impacts of a Physician-targeted Price Transparency Tool on Medication Out-of-pocket Costs
The goal of this study is to evaluate whether presenting patient out-of-pocket cost information to the provider at the time of prescribing leads to orders for medications with lower out-of-pocket costs.
- Trial name
- NCT04940988
- Testing
- Real-time benefits check
- Where
- United States
- Volunteers
- 21,401 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Heart Failure
SAFEty and Efficacy of HOME-based Hospitalization Versus Inpatient Care for Patients With Acute Heart Failure in Chronic Heart Failure.
Evaluation of the efficacy, safety and and cost of home care versus conventional hospitalization care at 3-months in patients with worsening chronic heart failure.
- Trial name
- SAFE-HOME (NCT03156686)
- Testing
- HOME-based hospitalization
- Where
- 2 sites in France
- Volunteers
- 10 people
- Sponsor
- French Cardiology Society
Second-degree Hemorrhoids
Comparison Between Single and Triple Rubber Band Ligation for the Treatment of Hemorrhoids
Rubber band ligation is a widely adopted treatment of internal hemorrhoids in busy coloproctology institutions. All three major hemorrhoidal clusters (left lateral, right anterior and right posterior) use to be ligated in order…
- Trial name
- NCT01383577
- Testing
- Single hemorrhoidal ligation, Triple hemorrhoidal ligation
- Where
- Brazil
- Volunteers
- 76 people
- Sponsor
- Federal University of Amazonas
Respiratory Tract Infections, Cough
Effectiveness of Improving Diagnostic and Communication Skills on Antibiotic Prescribing Appropriateness in Acute Cough
Despite their marginal benefit, about 60% of uncomplicated acute lower respiratory infections (ALRTI) are currently treated with antibiotics.
- Trial name
- ISAAC-CAT (NCT03931577)
- Testing
- C-reactive protein rapid testing, Communication skill enhancement
- Where
- Spain
- Volunteers
- 2,940 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Cataract
Economic Evaluation of Femtosecond Laser Assisted Cataract Surgery
Cataract is the leading cause of blindness worldwide and cataract surgery is the most frequent surgery performed in France. A new technology, the femtosecond laser-assisted cataract surgery, has to be compared with…
- Trial name
- FEMCAT (NCT01982006)
- Testing
- Cataract surgery with Phacoemulsification, Femtosecond laser-assisted cataract surgery
- Where
- 5 sites in France
- Volunteers
- 920 people
- Sponsor
- University Hospital, Bordeaux
Hyperglycemia, Obesity
Primary Care Community Partnerships to Prevent Diabetes
The purpose of this study is to determine if providing free-of-charge access to a group-based lifestyle intervention delivered in partnership with the community is cost-effective for the prevention of type 2 diabetes.
- Conditions
- Hyperglycemia, Obesity, Diabetes Mellitus
- Trial name
- RAPID (NCT00656682)
- Testing
- Dietitian Counseling Alone, Dietitian Plus Community Group Lifestyle
- Where
- United States
- Volunteers
- 509 people
- Sponsor
- Northwestern University
Colorectal Neoplasm
Enhancing Prevention Pathways Toward Tribal Colorectal Health
Recent improvements in colorectal cancer (CRC) incidence, mortality, stage at diagnosis, and survival in the general U.S. population have been attributed to routine screening with prompt removal of polyps, early detection, and…
- Trial name
- NCT02882620
- Testing
- High Intensity (Group 1), Medium Intensity (Group 2), Reference Group (Group 3)
- Where
- United States
- Volunteers
- 1,788 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Neoplasms, Colorectal, Neoplasm Metastasis
A Longitudinal Study of Colorectal Cancer Patients With Metastatic Disease in Middle-Norway
The main objective is to provide original research results that may change clinical practice related to metastatic colorectal cancer.
- Trial name
- NCT02395224
- Testing
- cancer treatment and follow-up according to current regional and national guidelines
- Where
- 7 sites in Norway
- Volunteers
- 354 people
- Sponsor
- Norwegian University of Science and Technology
Hypothermia, Heart Arrest
Clinical and Economical Interest of Endovascular Cooling in the Management of Cardiac Arrest (ICEREA Study)
According to international guidelines, mild therapeutic hypothermia is recommended for resuscitated patients after cardiac arrest due to ventricular fibrillation.
- Trial name
- NCT00392639
- Testing
- Comparison of 2 cooling procedures
- Where
- France
- Volunteers
- 389 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postoperative Complications
Clinical Outcomes and Costs Analyses in Use of Goal Directed Therapy
The aim of the study is to evaluate clinical and economic impact of Goal Directed Fluid Therapy according to NICE haemodynamic protocol.
- Trial name
- NCT01995786
- Testing
- Goal Directed Fluid Therapy FloTrac/Vigileo
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Regina Elena Cancer Institute
Esthetic Zone, Single Tooth Lost
Cost Effectiveness of Various Implant Placement Protocols in the Esthetic Zone
Loss of teeth in the anterior upper jaw significantly affects both well-being and chewing function. Nowadays, dental implants are the treatment of choice for replacing missing teeth with fixed dental prostheses and are often…
- Conditions
- Esthetic Zone, Single Tooth Lost, Accuracy of Dental Implants, Dimensional Changes
- Trial name
- NCT05940662
- Testing
- Immediate Implant Placement, Early Implant Placement, Late Implant Placement
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- University of Bern
Chronic Disease
Analysis of the Efficiency of a Chronic Disease Self-Management Programme in a Vulnerable Population in Five European Countries
According to the World Health Organization (WHO), it is estimated that around 35% of women and 29% of men are affected by chronic conditions and this percentage is clearly influenced by specific risk factors, such as lifestyle…
- Trial name
- EFFICHRONIC (NCT03840447)
- Testing
- Chronic Disease Self-Management programme
- Where
- France
- Volunteers
- 235 people
- Sponsor
- University Hospital, Montpellier
Arhythmia
Comparison and Analysis of Functionality, Safety, Cost-effectiveness, and Environmental Impact of Reprocessed and New Ablation Catheters in Electrophysiological Procedures.
This study evaluates whether re-sterilized (reprocessed) ablation catheters are as effective and safe as new ablation catheters when used for electrophysiological procedures.
- Trial name
- RE-USE EP (NCT07522424)
- Testing
- Ablation - new, Ablation - reprocessed
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- Ivan Zeljkovic
Substance Use Disorders, Recidivism
Preventing OUD in Justice-Involved Youth
The United States is experiencing an opioid epidemic. Sadly, opioid-related fatalities are on the rise, causing profound emotional, financial, and cultural impacts.
- Trial name
- POST (NCT04901312)
- Testing
- Adolescent Community Reinforcement Approach, Assertive Continuing Care, Trauma Affect Regulation Guide for Education and Therapy
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- Seattle Children's Hospital
Aging, Elderly
Successful Aging and Age-related Decline
Recent studies have shown promising cognitive and physical interventions aimed at slowing down ageing-related declines in quality of life, but they lack strong ecological validity (brief durations, unrealistic goals, no…
- Conditions
- Aging, Elderly, Cognitive Decline, Physical Decline
- Trial name
- MyAgeWell (NCT06376656)
- Testing
- Cognitive stimulation, Physical activity
- Where
- Malaysia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sunway University
Frail Elderly Syndrome
Transforming Primary Care for Older Canadians Living With Frailty
It is well known that older Canadians are high users of health care services. What is less well known is that the health care system is not well-designed to meet the needs of those who use it most.
- Trial name
- NCT03442426
- Testing
- Integrated model of primary care
- Where
- 3 sites in Canada
- Volunteers
- 695 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Low Back Pain
Efficacy and Cost: Benefit Ratio of 0, 1, and 2 Medial Branch Blocks for Lumbar Facet Joint Radiofrequency Denervation
Lumbar zygapophysial (facet) joint pain is a common cause of low back pain. Radiofrequency (RF) denervation is an effective and low risk treatment of chronic low back pain of suspected facet joint etiology.
- Trial name
- NCT00484159
- Testing
- Radiofrequency denervation of medial branches, 0.5% bupivacaine, 2% lidocaine
- Where
- 2 sites in United States
- Volunteers
- 151 people
- Sponsor
- Johns Hopkins University
Emotional Disorder, Depression
Cost-benefit Evaluation of a Transdiagnostic Psychological Treatment for Emotional Disorders in Primary Care
The aim of this study is to compare, in cost-effectiveness and cost-utility terms, a brief transdiagnostic cognitive-behavioural therapy in two different modes, individual and group, with the treatment usually administered in…
- Conditions
- Emotional Disorder, Depression, Somatoform Disorders, Anxiety Disorders
- Trial name
- PsicAP-Costs (NCT04847310)
- Testing
- Group brief transdiagnostic cognitive-behavioral therapy, Individual brief transdiagnostic cognitive-behavioral therapy, Treatment as usual
- Where
- 3 sites in Spain
- Volunteers
- 128 people
- Sponsor
- Universidad de Córdoba
Influenza Vaccine, Cost-Benefit Analysis
Cost-consequence Analysis of Influenza Vaccination in a Teaching Hospital in Rome
Flu vaccination, as well as being effective to prevent seasonal influenza, decreases staff illness and absenteeism and reduces costs resulting from loss of productivity.
- Trial name
- NCT06304038
- Testing
- Flu Vaccine
- Where
- Italy
- Volunteers
- 5,483 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Colorectal Neoplasms
Quality of Life of Patients With Colorectal Neoplasm and Cost-Effectiveness Analysis of Colorectal Cancer Screening
Introduction: Colorectal cancer (CRC) is the second most common cancer among Chinese in Hong Kong and the second leading cause of cancer death in this population.
- Trial name
- NCT02038283
- Where
- 3 sites in Hong Kong
- Volunteers
- 587 people
- Sponsor
- The University of Hong Kong