Clinical trials: Cost Effectiveness
Hilar Cholangiocarcinoma
Efficacy and Cost Analysis of Plastic Stent Compare to Metallic Stent in Hilar Cholangiocarcinoma
The purpose of this study is to compare the adequacy of unilateral endoscopic biliary drainage using metallic stent with plastic stent in unresectable, complex, hilar, cholangiocarcinoma and cost analysis.
- Trial name
- NCT00721175
- Testing
- biliary stent (self expandable metallic stent), PS
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Khon Kaen University
Activities of Daily Living, Everyday Activities
The Cancer Home Life Intervention Study. A Randomised, Controlled Multicentre Trial and a Health Economic Evaluation
The purpose of this study is to examine the effectiveness and cost-effectiveness of the Cancer Home Life Intervention compared to usual care on performance of and participation in everyday activities and quality of life in people…
- Conditions
- Activities of Daily Living, Everyday Activities, Palliative Care, Cancer
- Trial name
- NCT02356627
- Testing
- The Cancer Home Life Intervention
- Where
- 2 sites in Denmark
- Volunteers
- 242 people
- Sponsor
- University of Southern Denmark
Chest Pain
Impact on Management of the HEART Risk Score in Chest Pain Patients
Aim of this study is to quantify the impact of the use of the HEART risk score on patient outcome and on costs in patients with chest pain presenting at the emergency room, as compared to not using the score.
- Trial name
- HEART-Impact (NCT01756846)
- Testing
- usual care, use of HEART risk score
- Where
- 9 sites in Netherlands
- Volunteers
- 3,666 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Chronic Obstructive Pulmonary Disease, Asthma
Effectiveness and Implementation of the Assessment of Burden of Chronic Conditions (ABCC)-Tool
This study is designed to evaluate the effectiveness and implementation of the Assessment of Burden of Chronic Conditions (ABCC)-tool for patients with COPD, asthma, diabetes mellitus type 2 or heart failure (and any combination…
- Conditions
- Chronic Obstructive Pulmonary Disease, Asthma, Diabetes Mellitus, Type 2, Heart Failure
- Trial name
- NCT04127383
- Testing
- Assessment of Burden of Chronic Conditions (ABCC)-tool
- Where
- Netherlands
- Volunteers
- 237 people
- Sponsor
- Maastricht University
Chronic Neck Pain, Neck Pain
Cost-Effectiveness Analysis of a Virtual Reality-Assisted Hypnotherapy Program on Quality of Life in Patients with Chronic Neck Pain: a Multicenter, Randomized, Prospective, Comparative, Open-Label, Parallel-Group Study
This randomized, prospective study aims to evaluate the effectiveness and cost-efficiency of a Virtual Reality (VR)-assisted hypnotherapy program on quality of life in patients with chronic neck pain.
- Trial name
- NCT06697795
- Testing
- Virtual Reality-Assisted Hypnotherapy, Standard Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- University of Beykent
Latent Tuberculosis, HIV
Quantiferon Gold Test for Detecting Tuberculosis (TB) Infection in HIV/AIDS Patients in South Africa
The purpose of this study is to use a cluster randomized trial to compare the effectiveness of linking the Quantiferon-gold in-tube test (QGIT) with routine CD4 testing to the routine use of the tuberculin skin test (TST), the…
- Trial name
- NCT02119130
- Testing
- QGIT
- Where
- 14 sites in South Africa
- Volunteers
- 3,506 people
- Sponsor
- Johns Hopkins University
Congenital Heart Disease
Fibrinogen Concentrate vs Cryoprecipitate
One of the most common hemostatic derangements in pediatric open- heart surgery is an acute acquired hypofibrinogenemia. This compromises fibrin clot generation and platelet aggregation, resulting in increased bleeding and…
- Trial name
- NCT03014700
- Testing
- Fibrinogen Concentrate, Cryoprecipitate
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
HIV, HIV Infections
Mobile Phone Technology for Prevention of Mother-to-Child Transmission of HIV: Acceptability, Effectiveness, and Cost (Kenya)
Although gains have been made in achieving the health-related Millennium Development Goals (MDG), much is still needed in countries affected by high levels of HIV/AIDS.
- Conditions
- HIV, HIV Infections, AIDS, Antiretroviral Therapy
- Trial name
- NCT01645865
- Testing
- Control, Intervention
- Where
- Kenya
- Volunteers
- 600 people
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
Refractory Angina Pectoris, Gene Transfer
Adenovirus Vascular Endothelial Growth Factor D (AdvVEGF-D) Therapy for Treatment of Refractory Angina Pectoris
The purpose of the study is to evaluate the safety and efficacy of catheter mediated endocardial adenovirus-mediated vascular endothelial growth factor-D (AdVEGF-D) regenerative gene transfer in patients with refractory angina to…
- Conditions
- Refractory Angina Pectoris, Gene Transfer, Coronary Artery Disease
- Trial name
- ReGenHeart (NCT03039751)
- Testing
- AdvVEGF-D, Control Rx
- Where
- 2 sites in Denmark, Finland
- Volunteers
- 63 people
- Sponsor
- Kuopio University Hospital
Blood Pressure, Pharmacy
Effectiveness of a Community Pharmacy-based Health Promotion Program on Hypertension in Bangladesh and Pakistan
The aim of this multi-country research project is to reduce the blood pressure of individuals with hypertension over a 18-month period in Bangladesh and Pakistan.
- Conditions
- Blood Pressure, Pharmacy, Cost-effectiveness
- Trial name
- NCT06148142
- Testing
- Pharmacy based health promotion
- Where
- Bangladesh
- Volunteers
- 3,600 people
- Sponsor
- Hitotsubashi University
Proximal Tibia Fracture
The Efficacy and Cost Effectiveness of Preoperative and Postoperative Cryotherapy in Proximal Tibia Fractures
Consenting patients with proximal tibia fractures will be randomized to 10 degree or 21 degree cryotherapy sleeves. Time to discharge and complications will be monitored.
- Trial name
- ARCTIC CAT (NCT01104831)
- Testing
- Cryotherapy, Room temperature cuff
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Obesity
Game of Stones: A Research Study That Texts Men to Help Them Lose Weight
In 2014, 24% of UK men were obese. However men rarely participate in weight loss programmes. This study looks at whether two interventions which show promise can help obese men lose weight and keep it off.
- Trial name
- NCT03040518
- Testing
- Narrative SMS, Endowment Incentive
- Where
- 2 sites in United Kingdom
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Stirling
Sciatica, Sciatica Due to Intervertebral Disc Disorder
Transforaminal Epidural Injection in Acute Sciatica
Patients suffering from sciatica are treated conservatively for the first 8 weeks due to the favourable prognosis. This period is preferably extended up to 14-16 weeks after which patients may opt for surgery.
- Conditions
- Sciatica, Sciatica Due to Intervertebral Disc Disorder, Sciatic Radiculopathy
- Trial name
- TEIAS (NCT03924791)
- Testing
- Lidocaine, Methylprednisolone Acetate, Dexamethasone
- Where
- 2 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- C.L.A.Vleggeert-Lankamp
Childhood Obesity
Hyvinkää Childhood Obesity Study (HCOS), Randomized Controlled Clinical Trial for Effectiveness and Costs of a 1-year Lifestyle Intervention.
The aim of this study is to evaluate the effects of lifestyle intervention on the management of childhood overweight and to explore the factors that contribute to the outcome, as well as the costs for the health care system.
- Trial name
- HCOS (NCT06126679)
- Testing
- 1-year dietary and physical activity intervention of childhood obesity
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Helsinki University Central Hospital
Pancreatic Necrosis
Study of a Lumen- Apposing, Covered, Self-Expanding Metal Stent (Axios™) Versus Multiple Double Pigtail Stents
The present study aims to compare the clinical efficacy and cost effectiveness of the AXIOS™ stent versus the "conventional" approach using double pigtail plastic stents in the treatment of patients with walled-off pancreatic…
- Trial name
- NCT02673541
- Testing
- AXIOS™ stent, Double Pigtail Stents
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Intermittent Claudication
(Cost) Effectiveness Study of Exercise Therapy in Patients With Peripheral Arterial Disease
The purpose of this study is to determine if supervised exercise therapy in a physiotherapeutic setting, with or without therapy feedback, is more (cost-)effective than exercise therapy based on a 'go home and walk' advice…
- Trial name
- EXITPAD (NCT00279994)
- Testing
- Exercise therapy, Accelerometer (PAM; Personal Activity Monitor), Oral Exercise Therapy advise
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Atrium Medical Center
Leukemia, Myelocytic, Acute
Voriconazole or Placebo in the Prophylaxis of Lung Infiltrates in Patients Undergoing Induction Chemotherapy for Acute Myelogenous Leukemia
The purpose of the study is to determine whether voriconazole is as effective as antifungal prophylaxis in patients undergoing chemotherapy for acute myelogenous leukemia (AML).
- Trial name
- NCT00152594
- Testing
- voriconazole
- Where
- 3 sites in Germany
- Volunteers
- 150 people
- Sponsor
- University of Cologne
Mouth, Edentulous
A Cost-effectiveness Analysis of the Single-implant Mandibular Overdenture Treatment
The aim of this study is to assess the cost-effectiveness of the mandibular overdenture retained by a single implant. The study hypothesis is that SIMO is more effective but more costly than the conventional denture, though this…
- Trial name
- SIMOECON (NCT02710357)
- Testing
- Mandibular Overdenture, Mandibular complete denture
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Interdisciplinary Communication, Postoperative Complications
Effects of Preoperative Multidisciplinary Team Meetings for High-risk, Adult, Noncardiac Surgical Patients
The current multicenter stepped wedge randomized cluster trial study aims to assess whether implementation of preoperative multidisciplinary team (MDT) discussions is (cost)effective for high risk noncardiac surgical patients.
- Conditions
- Interdisciplinary Communication, Postoperative Complications, Noncardiac Surgery, Surgical Procedures, Operative
- Trial name
- PREPARATION (NCT05703230)
- Testing
- Structured preoperative multidisciplinary team meeting
- Where
- 14 sites in Netherlands
- Volunteers
- 1,200 people
- Sponsor
- Rijnstate Hospital
Remote Consultation, Community Psychiatry
Psychiatric Consultation Through Videoconference in a Primary Care Setting
In our study we will aim to examine the issues of cost analysis, quality of life, clinical efficacy and satisfaction of psychiatric consultations through videoconference in a primary care setting in comparison with in-person…
- Trial name
- NCT00298961
- Testing
- Videoconference equipment FALCON/IP
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Sha'ar Menashe Mental Health Center