Clinical trials: Cost Effectiveness
Food Insecurity
Comparing the Effectiveness of Two Produce Prescription Approaches On Fruit and Vegetable Intake and Food Security, While Exploring Implementation Outcomes Such as Reach, Implementation, Sustainability, and Cost
The produce prescription program is one type of food is medicine (FIM) programs, where healthcare providers "prescribe" fruits and vegetables (F\&V) to patients with low household incomes, experience food insecurity, and one or…
- Trial name
- NutriConnect (NCT06263751)
- Testing
- Product prescription program- NutriConnect Credit, Product prescription program- NutriConnect Delivery
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Washington University School of Medicine
Renal Calculi, Nephrolithiasis
Comparison Between Different Types of Flexible Ureteroscopes
The current study aims to compare the performance of three distinct single-use digital flexible ureteroscope types in terms of cost-effectiveness, postoperative complications, operating time, and stone-free rates (SFRs).
- Trial name
- FURS (NCT07360353)
- Testing
- LithoVue™ (Boston Scientific Corporation), WiScope® (OTU Medical Inc. (Silicon Valley, USA)), Single-Use Ureterorenoscope (Scivita Medical Technology Co., Ltd.)
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Ain Shams University
Dyspnea
B-type Natriuretic Peptide for Acute Shortness of Breath EvaLuation (BASEL) Study - Private Practice
Cost-effective management of heart failure and pulmonary disease is of paramount importance. Unfortunately, the rapid and accurate differentiation of heart failure from other causes of dyspnea in private practice is challenging.
- Trial name
- NCT00130611
- Testing
- BNP measurement, Clinical examination
- Where
- 9 sites in Germany, Switzerland
- Volunteers
- 250 people
- Sponsor
- University Hospital, Basel, Switzerland
Morbid Obesity
Cost-Effectiveness and Outcome of Robot-assisted Vs Laparoscopic Roux-en-Y Gastric Bypass
The objective of this randomized controlled trial is to compare perioperative outcomes between laparoscopic and robotic approaches in patients with severe obesity who are candidates for RYGB.
- Trial name
- LvRRYGB (NCT07153419)
- Testing
- Laparoscopic and robotic (DaVinci) RYGB
- Where
- Italy
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Chronic Renal Failure
Cost Utility Analysis of Erythropoietin for Anemia Treatment in Hemodialysis Patients
To study the cost utility analysis of Erythropoietin (EPO) for maintaining the different hemoglobin (Hb) target levels in anemic hemodialysis patient in routine clinical practice.
- Trial name
- CUAEPO (NCT01049711)
- Testing
- erythropoietin
- Where
- Thailand
- Volunteers
- 152 people
- Sponsor
- Mahidol University
Knee Osteoarthritis
ROSA Knee System vs Conventional Total Knee Arthroplasty
This is a randomized clinical study, in which 150 patients with end-stage osteoarthritis will be enrolled to ROSA®-assisted knee arthroplasty or conventional knee arthroplasty.
- Trial name
- ROSA_RCT (NCT05685693)
- Testing
- Robotic-assisted total knee arthroplasty (raTKA), conventional total knee arthroplasty
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Zuyderland Medisch Centrum
Malaria, Soil Transmitted Helminths
Effectiveness and Cost-effectiveness of Integrated Model for Malaria and Helminth Control
Malaria remains a major health problem, especially among children living in sub-Saharan Africa where more than 90% of the disease and deaths occur.
- Conditions
- Malaria, Soil Transmitted Helminths, Schistosomiasis, Seasonal Malaria Chemoprevention
- Trial name
- MALHELMIN (NCT06182176)
- Testing
- Sulphadoxine-pyrimethamine and Amodiaquine
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Severe Acute Malnutrition
Modified Dosage for Severe Acute Malnutrition
Protocols for the community-based management of acute malnutrition (CMAM) have not changed significantly for more than 20 years, with relatively complex treatment protocols and persistent supply chain challenges that have limited…
- Trial name
- MODAM-SAM (NCT06061484)
- Testing
- ready-to-use therapeutic food (RUTF), Amoxicillin
- Where
- 3 sites in Ethiopia
- Volunteers
- 2,400 people
- Sponsor
- Action Against Hunger USA
Mental Stress
The Effectiveness and Cost-effectiveness of Mental Wellness Youth Hub
The proposed study is to be carried out with 6000-7000 youths aged 12 - 24 in Hong Kong. The purpose of the study is to investigate the effectiveness and cost-effectiveness of a Hub project for young people: LevelMind@JC.
- Trial name
- NCT04840303
- Testing
- LevelMind@JC Mental Wellness Youth Hubs
- Where
- Hong Kong
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Frailty
Effect of an Exercise Program for Frail Older Adults
Despite the high level of evidence for physical activity as a countermeasure for frailty, the current Flemish standard of care does not include structural PA interventions for community-dwelling frail older adults.
- Trial name
- AA@HOME (NCT05946109)
- Testing
- ACTIVE-AGE@home
- Where
- Belgium
- Volunteers
- 195 people
- Sponsor
- Universitair Ziekenhuis Brussel
Hospital Costs, Length of Stay
A Trial of the Cost Effectiveness of IV Acetaminophen in Bariatric Surgery
Bariatric surgery is the only proven and effective long term treatment for morbid obesity. In an attempt to reduce patients' post-operative hospital stay, lower associated health care costs, and improve satisfaction scores, St…
- Conditions
- Hospital Costs, Length of Stay, Postoperative Pain Score, Patient Satisfaction
- Trial name
- NCT02233400
- Testing
- Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 113 people
- Sponsor
- St. Luke's Hospital and Health Network, Pennsylvania
Bronchiectasis
Randomised Open Label Trial of Hypertonic Saline and Carbocisteine in Bronchiectasis (CLEAR)
Patients with bronchiectasis (BE) suffer from a persistent cough, daily sputum expectoration, recurrent chest infections, and a poor health-related quality of life.
- Trial name
- CLEAR (NCT04140214)
- Testing
- Hypertonic saline, Carbocysteine 750 MG
- Where
- 20 sites in United Kingdom
- Volunteers
- 288 people
- Sponsor
- Belfast Health and Social Care Trust
Osteoarthritis, Knee
Spa Therapy in Knee Osteoarthritis: Study on Cost/Effectiveness - Cost/Utility and Possible Mechanisms of Action
The aim of this study is to evaluate both cost/effectiveness- cost/utility and the possible mechanisms of action of spa therapy in patients with primary knee osteoarthritis (OA).
- Trial name
- NCT01538043
- Testing
- local mud-pack therapy and balneotherapy
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Siena
Human Immunodeficiency Virus
Package of Resources for Assisted Contact Tracing: Implementation, Costs, and Effectiveness
Having health workers assist HIV-infected persons with the recruitment and testing of their sexual contacts and biological children is an effective and efficient way of identifying additional HIV-infected persons in need of HIV…
- Trial name
- PRACTICE (NCT05343390)
- Testing
- Enhanced implementation package, Standard implementation package
- Where
- 33 sites in Malawi
- Volunteers
- 841 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Breast Cancer
Evaluation of the Short Message Service Effectiveness in the Screening Invitation Strategy for Breast Cancer (USIMaPI)
Each year in France, breast cancer affects about 48,000 women and is the first cause of cancer death in women with 11,900 deaths estimated.
- Trial name
- USIMaPI (NCT03000920)
- Testing
- SMS before invitation, SMS Reminder 1
- Where
- 4 sites in France
- Volunteers
- 12,000 people
- Sponsor
- University Hospital, Tours
Rehabilitation, Spinal Fusion
Effect of a Case Manager to Assist the Rehabilitation for Lumbar Spinal Fusion Patients. A Randomised Controlled Trial.
The aim of the current study is to examine the effect of a case manager-assisting rehabilitation program compared to usual physical rehabilitation for patients undergoing a lumbar spinal fusion on functional disability, pain, and…
- Conditions
- Rehabilitation, Spinal Fusion, Case Managers
- Trial name
- NCT03433443
- Testing
- Case manager assisted rehabilitation, Usual physical rehabilitation
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cholelithiasis
Cost Effectiveness Analysis of Cholecystectomy, Projected Long Term Outcomes and Complications Evaluation
Participation in this research study does not involve any procedures. Health preference will be ascertained through standard techniques including time-tradeoff, standard gamble, and rating scale to assess risks regarding…
- Trial name
- NOTES (NCT01117415)
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Common Bile Duct Calculi
The Cost Effectiveness of Endoscopic Ultrasound ( EUS ) Based Strategy in Diagnosis of Common Bile Duct Stones
Multiple reports in the literature showed the efficacy of EUS comparable to ERCP in the diagnosis of common bile duct ( CBD ) stone.
- Trial name
- NCT02349568
- Testing
- High risk group, Intermediate risk group
- Where
- Thailand
- Volunteers
- 141 people
- Sponsor
- Prince of Songkla University
Mental Disorders
Evaluating the Clinical Cost-effectiveness of Two Primary Mental Health Service Frameworks in Yogyakarta, Indonesia
This study is a cluster randomised controlled trial, which aims to examine the short-term strategy of addressing treatment gap through increasing primary mental health service capacity.
- Trial name
- NCT02700490
- Testing
- Psychotherapy
- Where
- Indonesia
- Volunteers
- 400 people
- Sponsor
- University of Cambridge
Critical Illness, Mechanical Ventilation
Cost-Effectiveness of Inhaled Sedation Versus Intravenous Propofol in Mechanically Ventilated Critically Ill Adults
The goal of this observational study is to learn whether inhaled sedation is a cost-effective alternative to intravenous propofol in mechanically ventilated critically ill adults admitted to the intensive care unit.
- Conditions
- Critical Illness, Mechanical Ventilation, Respiratory Insufficiency
- Trial name
- NCT07734350
- Testing
- Isoflurane, Propofol (Astra-Zeneca)
- Volunteers
- 400 people
- Sponsor
- Hospital H+ Queretaro