Clinical trials: Cost-Benefit Analysis
Diabetes Mellitus, Hyperglycemia
Intervening in Diabetes With Healthy Eating, Activity, and Linkages To Healthcare - The I-D-HEALTH Study
The purpose of this study is to compare ways of giving advice and providing support to improve diet and physical activity in adult primary care patients with elevated body mass index and dysglycemia.
- Conditions
- Diabetes Mellitus, Hyperglycemia, Obesity, Glucose Metabolism Disorders
- Trial name
- I-D-HEALTH (NCT01435603)
- Testing
- Standard Lifestyle Advice, Advice Plus Lifestyle Intervention
- Where
- 2 sites in United States
- Volunteers
- 331 people
- Sponsor
- Northwestern University
Hip Fractures
Geriatric Fracture Centers - Evaluation of a Geriatric Co-management Program
The study will assess patients with at least one major AE related to treatment / hospitalization / immobilization in the Geriatric Fracture Center (GFC) group compared to the usual care group.
- Trial name
- NCT02297581
- Where
- 12 sites in United States, Austria and 4 more
- Volunteers
- 282 people
- Sponsor
- AO Innovation Translation Center
HIV
Gathering Records to Evaluate Antiretroviral Treatment-Malawi ( GREAT )
To achieve global goals for the treatment of HIV, most high-prevalence countries are experimenting with and scaling up differentiated service delivery models (DSD).
- Trial name
- GREAT (NCT04158895)
- Testing
- Routine medical record data collection
- Where
- Malawi
- Volunteers
- 1,000,000 people
- Sponsor
- Boston University
Competencies of Midwives, Cost-benefit Analysis of Modular Training
Effect of Skill Birth Attendant Training to Improve the Competency of Service Providers
This clinical trial's primary goal is to compare birth attendants' competencies. It aims to answer the questions: Does the new modular training package enhance the competencies of skilled birth attendants? Does the competencies…
- Trial name
- NCT05866016
- Testing
- Skill birth attendant training
- Where
- 2 sites in Nepal
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ministry of Health Gandaki Province, Nepal
Accidental Falls, Health Behavior
Kuopio Fall Prevention Study.
This study evaluates the 6 month exercise intervention (Taiji and gym course) combined with free use of communal recreation facilities in fall prevention.
- Conditions
- Accidental Falls, Health Behavior, Aging
- Trial name
- KFPS (NCT02665169)
- Testing
- Supervised physical exercise, Health counselling
- Where
- Finland
- Volunteers
- 914 people
- Sponsor
- Kuopio University Hospital
Respiratory Therapy, Respiration, Artificial
Initiation of Home Mechanical Ventilation at Home in Patients With Chronic Hypercapnic Respiratory Failure
Objective: To prove that initiation of chronic ventilatory support at home, in patients with chronic hypercapnic respiratory failure due to neuromuscular disease (NMD) or thoracic cage problem is not inferior compared to…
- Conditions
- Respiratory Therapy, Respiration, Artificial, Positive-Pressure Respiration, Neuromuscular Diseases
- Trial name
- Homerun (NCT03203577)
- Testing
- Initiation of mechanical ventilation
- Where
- Netherlands
- Volunteers
- 96 people
- Sponsor
- University Medical Center Groningen
Ambulatory Care Information Systems, Clinical Decision Support Systems
Improving Safety and Quality With Outpatient Order Entry
The purpose of this study is to evaluate the impact of integrating ambulatory computerized physician order entry (ACPOE) and advanced clinical decision support systems (CDSS) on safety and quality domains in the ambulatory…
- Trial name
- NCT00243334
- Testing
- Integration of advanced clinical decision support with ambulatory computerized physician order entry
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Brigham and Women's Hospital
Pregnancy, HIV
Benefits and Costs of Integrating Sexual-Reproductive Health and HIV Services in Kenya and Swaziland
The overarching aim of the Integra Initiative is to strengthen the evidence base on the impact of integrating family planning (FP), postnatal care (PNC) and HIV services in sub-Saharan Africa.
- Trial name
- Integra (NCT01694862)
- Testing
- Integrated FP/PNC service delivery
- Where
- 2 sites in Eswatini, Kenya
- Volunteers
- 4,763 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Stroke, Ischemic Attack, Transient
Post-Stroke Disease Management - Stroke Card
Patients after ischemic stroke are at high risk of recurrent cardiovascular events and of developing post-stroke complications. There is a substantial gap between risk factor management in real life and that recommended by…
- Conditions
- Stroke, Ischemic Attack, Transient, Secondary Prevention, Disease Management
- Trial name
- Stroke Card (NCT02156778)
- Testing
- Active Comparator: Extended Standard Care (Stroke Card), Active Comparator: Standard Care
- Where
- Austria
- Volunteers
- 2,149 people
- Sponsor
- Medical University Innsbruck
Malnutrition
Cost-effectiveness Study of the New Nutrition Screening Tool CIPA at Hospital Admission
Objectives: To evaluate the cost-effectiveness of implementing a malnutrition screening tool "CIPA" at the Hospital Universitario Nuestra Señora de la Candelaria (HUNSC), comparing the impact on health and the healthcare costs of…
- Trial name
- NCT02721706
- Testing
- CIPA nutritional screening tool
- Where
- Spain
- Volunteers
- 823 people
- Sponsor
- University Hospital of the Nuestra Señora de Candelaria
Respiratory Tract Infections
Point-of-care Testing of Respiratory Pathogens at Pediatric Emergency Room
The main objective of the trial is to evaluate the effect of point-of-care testing of respiratory pathogens at a pediatric emergency room on the antibiotic consumption and hospital admissions in acutely ill children.
- Trial name
- Hevi-RCT (NCT03932942)
- Testing
- QIAstat at pediatric emergency room
- Where
- Finland
- Volunteers
- 1,350 people
- Sponsor
- University of Oulu
Heart Failure, Ventricular Dysfunction, Left
ECG Low Ejection Fraction Detection and Guiding in AI Navigated Treatment Era
Asymptomatic left ventricular systolic dysfunction (ALVSD), identified as a key component of stage B heart failure (HF) by AHA/ACC guidelines, is a common precursor to clinically overt HF.
- Conditions
- Heart Failure, Ventricular Dysfunction, Left, Artificial Intelligence, Early Diagnosis
- Trial name
- ELEGANT (NCT06968533)
- Testing
- AI-ECG guided diagnosis
- Where
- Taiwan
- Volunteers
- 13,350 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Autism Spectrum Disorder
Improving Autistic Children's Experiences of Dental Care With Class-integrated Social Story
Children with autism spectrum disorder (ASD) are more likely to have unmet dental needs. Due to hypersensitivity and oral defensiveness, new or unexpected stimuli during dental examinations often precipitate anxiety and stress.
- Trial name
- NCT07166978
- Testing
- Social story
- Where
- Hong Kong
- Volunteers
- 106 people
- Sponsor
- The University of Hong Kong
Chronic Disease
Cost-benefit Analysis of a Clinical Pharmacist Intervention
Clinical pharmacy services are vital in the prevention of adverse drug events (ADEs) in clinical practice, extending beyond the hospital to chronic disease management in outpatient settings.
- Trial name
- NCT03803033
- Testing
- Clinical pharmacy-based home medication management review service
- Where
- Jordan
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Depressive Disorder
Increasing Cost-effectiveness of Inpatient Treatment of Affective Disorders
The cost-effectiveness of a new, guideline oriented sequential inpatient - outpatient treatment model will be investigated. Secondary outcomes are: patient satisfaction, practitioners' satisfaction and influence on work.
- Trial name
- INCA (NCT00662428)
- Testing
- Symptom based discharge management, Treatment as usual
- Where
- 5 sites in Germany
- Volunteers
- 202 people
- Sponsor
- University Hospital Freiburg
Uterine Cervical Neoplasm, Laparotomy
Different Surgical Approaches in Patients of Early-stage Cervical Cancer
This multi-center, randomized controlled study aims to compare the survival outcomes (including overall survival, progression-free survival and disease-free survival between Chinese uterine cervical patients receiving different…
- Conditions
- Uterine Cervical Neoplasm, Laparotomy, Laparoscopy, Survival
- Trial name
- NCT03739944
- Testing
- Laparotomic radical hysterectomy, Laparotomic radical trachelectomy, Laparoscopic radical hysterectomy
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Lei Li
Drug-resistant Tuberculosis, HIV Coinfection
Pragmatic Use of Next-generation Sequencing for Management of Drug-resistant Tuberculosis
TS ELiOT is a stepped-wedge, cluster randomized trial assessing the effect of a next-generation sequencing-based strategy on rifampin-resistant tuberculosis management and patient outcomes.
- Conditions
- Drug-resistant Tuberculosis, HIV Coinfection, Cost-Benefit Analysis
- Trial name
- TSELiOT (NCT05553236)
- Testing
- Targeted next-generation sequencing
- Where
- South Africa
- Volunteers
- 2,500 people
- Sponsor
- University of California, San Francisco
HIV, Latent Tuberculosis
Testing for Tuberculosis in the United Kingdom HIV Infected Population
Human Immunodeficiency Virus (HIV) is the strongest individual risk factor for the reactivation of tuberculosis (TB) after previous exposure to Mycobacterium tuberculosis (MTb).
- Trial name
- NCT02712671
- Testing
- Chest radiograph, Blood interferon gamma release assay, Tuberculin skin testing (TST)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- University College, London
Financial Benefit, Colorectal Cancer
Emilia-Romagna Surgical Colorectal Cancer Audit- ESCA
Focus of this project is to evaluate the possible financial benefit resulting from an optimization of surgical outcomes throughout a collaborative and systematic auditing activity.The primary objective of this analysis is to…
- Conditions
- Financial Benefit, Colorectal Cancer, Surgery, Auditing Activity
- Trial name
- ESCA (NCT03982641)
- Testing
- all colorectal cancer surgical procedures
- Where
- 9 sites in Italy
- Volunteers
- 1,400 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Cost-effectiveness Analysis, Chronic Kidney Disease Requiring Chronic Dialysis
Cost-effectiveness of Urgent-start Therapies Hemodialysis and Peritoneal Dialysis
This study will evaluate the cost-effectiveness of unplanned dialysis (peritoneal dialysis and hemodialysis) in chronic kidney disease (CKD) during the first year of therapy in a single center.
- Trial name
- NCT03474367
- Where
- Brazil
- Volunteers
- 198 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho