Clinical trials: Cost-Effectiveness
Depression, Social Anxiety
Effectiveness and Cost Effectiveness of OkeyMind for Social Anxiety Among Youth
This randomized controlled trial aims to evaluate the effectiveness and cost-effectiveness of a mobile-based psychoeducation program (OkeyMind) in mitigating symptoms associated with social anxiety among youth.
- Trial name
- NCT06490315
- Testing
- OkeyMind intervention, Wait-list control
- Where
- Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hong Kong Shue Yan University
Fall
Training- and Cost-effectiveness of an Internet-based Lifestyle-integrated Functional Exercise Program (iLiFE)
Falls are the second leading cause of unintentional injury and death around the globe. About one in every three older adults falls each year worldwide.
- Trial name
- NCT05694494
- Testing
- internet-based Lifestyle-integrated Functional Exercise (iLiFE), upper limb exercise training
- Where
- Hong Kong
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
HIV Infections
PrEP Seguro: Antiretroviral-based HIV Prevention Among Men at High Risk in Mexico
The objective of this R34 application is to prepare for testing innovative user-centered ways to promote PrEP adherence at scale.
- Trial name
- NCT03674983
- Testing
- Conditional Economic Incentive (CEI)
- Where
- Mexico
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Brown University
Pain
Post-operative Pain Management In Patients Undergoing Hullax Valgus Surgery
The purpose of this study is to investigate the efficacy and cost analysis of intravenous fentanyl combined with either local anesthesia infiltration or peroneal nerves block in patients with Hallux Valgus undergoing orthopedic…
- Trial name
- NCT01960595
- Testing
- IV fentanyl PCA, local bupivacaine infiltration and post-OP IV fentanyl PCA, Nerve Blocks and post-OP IV fentanyl PCA
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Knee Osteoarthritis, Hip Osteoarthritis
Use of Knotless Suture for Closure of Total Hip and Knee Arthroplasties
Barbed sutures offer several potential advantages in layered wound closure of hip and knee replacement surgeries. It use is gaining increased acceptance across many of the other surgical disciplines at this time.
- Trial name
- NCT00834483
- Testing
- Knotless suture for wound closure, Layered traditional wound closure (monocryl)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Asthma
REALL: A Retrospective Observational Study to Compare the Effectiveness and Cost-Effectiveness Between Different Step-3 Asthma Treatment Strategies
This is a retrospective observational study utilising anonymised individual patient clinical and prescribing information routinely collected by UK General Practitioners (GPs).
- Trial name
- REALL (NCT00628563)
- Where
- United Kingdom
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Hemorrhoids, Fissure in Ano
Multi-Drug Analgesia vs. Standard Solution for Anal Surgery
The primary aim is to test the magnitude and duration of analgesia provided by single dose multi-drug analgesia administered for perianal block, and compare with standard solution (Marcaine \& Lidocaine in 1:1 mixture - Total 60…
- Conditions
- Hemorrhoids, Fissure in Ano, Fistula;Rectal
- Trial name
- NCT03105674
- Testing
- Multi-drug local anesthetics (Combination), Standard local anesthetics (Combination)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Depression
Behavioral Medicine Intervention With Depressed Patients in a Community Health Center Setting
The linkage between the Massachusetts General Hospital (MGH)-Community Health Associates and the MGH-Benson Henry Institute for Mind-Body Medicine began in order to address the concern of providing affordable, easily accessible…
- Trial name
- NCT01330420
- Testing
- Relaxation Response Resiliency Program for Depression
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Prediabetic State & High Risk Individuals on the Basis of Diabetes Risk Score
(Pakistan Diabetes Prevention Program PDPP)
The Karachi-based Pakistan Diabetes Prevention Study aims to address key issues in the prevention of type 2 diabetes. Approximately 20,000 people From four communities will be screened for diabetes risk factors using a…
- Trial name
- PDPP (NCT01530165)
- Testing
- Life style intervention
- Where
- Pakistan
- Volunteers
- 1,564 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Morbidity of Hysterectomy
Finhyst 2006: Study on Morbidity of Hysterectomies in Finland
The purpose of this study is to analyze prospectively all hysterectomies performed in Finland for benign indications including all 46 public hospitals performing hysterectomies and also 7 private clinics.
- Trial name
- Finhyst 2006 (NCT00744172)
- Testing
- laparoscopy, vaginal, abdominal
- Where
- Finland
- Volunteers
- 5,279 people, healthy volunteers welcome
- Sponsor
- Society for Gynecological Surgery in Finland
Mouth, Edentulous
A Cost-effectiveness Analysis of the Single-implant Mandibular Overdenture Treatment
The aim of this study is to assess the cost-effectiveness of the mandibular overdenture retained by a single implant. The study hypothesis is that SIMO is more effective but more costly than the conventional denture, though this…
- Trial name
- SIMOECON (NCT02710357)
- Testing
- Mandibular Overdenture, Mandibular complete denture
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Sexually Transmitted Infection, HIV/AIDS
Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes (Philani Ndiphile)
This study aims to evaluate different screening strategies to decrease the burden of Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT) and Trichomonas vaginalis (TV) among pregnant women, and reduce adverse birth outcomes.
- Conditions
- Sexually Transmitted Infection, HIV/AIDS, Cost-effectiveness, Birth Outcomes
- Trial name
- NCT04446611
- Testing
- First antenatal care + test-of-cure, First antenatal care + week 30-34 gestation (no test-of-cure)
- Where
- South Africa
- Volunteers
- 2,247 people, healthy volunteers welcome
- Sponsor
- Foundation for Professional Development (Pty) Ltd
Cholera
Introduction of Cholera Vaccine in Bangladesh
The purpose of this study is to conduct and evaluate the feasibility and effectiveness of a mass cholera vaccination program to reduce diarrhea due to Vibrio cholerae in a high incidence urban area.
- Trial name
- ICVB (NCT01339845)
- Testing
- ShanChol, Vaccine and behaviour
- Where
- Bangladesh
- Volunteers
- 240,000 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Orthodontic Relapse, Retention in Orthodontic
Effectiveness, Patient Acceptance, and Cost Estimation of 3D-printed Retainer Compared to Hawley Retainer in Expansion Case: a Randomized Controlled Trial
Expansion of the arches is generally considered highly unstable and prone to relapse regardless of the type of expansion. Retention appliances play a vital role in preserving these changes.
- Trial name
- NCT07659041
- Testing
- 3D printed retainer, Hawley retainer
- Where
- 3 sites in Malaysia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Chronic Disease, Quality of Life
Electronic Patient Reported Outcome (ePRO) Mobile Application Pragmatic Trial
Canadian and international health care systems require solutions on how to address the needs of a relatively small population that take up a large portion of health care resources.
- Trial name
- NCT02917954
- Testing
- ePRO Tool Intervention
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Chest Pain
Impact on Management of the HEART Risk Score in Chest Pain Patients
Aim of this study is to quantify the impact of the use of the HEART risk score on patient outcome and on costs in patients with chest pain presenting at the emergency room, as compared to not using the score.
- Trial name
- HEART-Impact (NCT01756846)
- Testing
- usual care, use of HEART risk score
- Where
- 9 sites in Netherlands
- Volunteers
- 3,666 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Female Reproductive Problem, Infertility
Use of Corifolitropin Alfa in Oocyte Donors
The purpose of this study is to determine if corifollitropin alfa (long-term gonadotropin administration) is effective in a controlled ovarian stimulation protocol in oocyte donors compared to daily gonadotropin administration…
- Trial name
- NCT02213627
- Testing
- Corifollitropin alfa, Recombinant FSH, HP-hMG
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Educational Problems, Resuscitation
Group Size in Basic Life Support (BLS) Courses
Basic Life Support (BLS) is important for outcome in cardiac arrest.Therefore, it is crucial to improve the quality of education in resuscitation training.
- Trial name
- NCT03773861
- Testing
- errors made in one BLS session
- Where
- Switzerland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cancer, Neoplasm
Enhancing Successful Return to Work of Employees With Cancer, by Supporting Employers (MiLES Intervention)
The objective of this randomized controlled trial (RCT) is to evaluate the effectiveness of the MiLES intervention targeted at employers, on successful return to work (RTW) of employees with cancer, compared to care as usual…
- Trial name
- MiLES (NCT06672887)
- Testing
- MiLES
- Where
- 5 sites in Netherlands
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Scalp Laceration
Comparison Study on Hair Apposition Technique Performed Between Nurses and Doctors in Emergency Department.
The purpose of this study is to compare the effectiveness, complications and benefits of Hair Apposition Technique(HAT)performed by nurses or doctors.
- Trial name
- NCT00353769
- Testing
- Hair Apposition Technique
- Where
- Singapore
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital