Clinical trials: Cost-Effectiveness
Cholangiocarcinoma, Cholangiopathy
Spanish Registry of Direct Cholangiopancreatoscopy by Single Operator
Endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) remain fundamental tools for the diagnosis and treatment of many pancreatobiliary diseases.
- Conditions
- Cholangiocarcinoma, Cholangiopathy, Biliary Stricture, Choledocholithiasis
- Trial name
- NCT07064447
- Testing
- Cholangiopancreatoscopy
- Volunteers
- 260 people
- Sponsor
- Germans Trias i Pujol Hospital
Healthy Infants
Lactobacillus Reuteri DSM 17938 and Prevention of Respiratory and Gastrointestinal Infections in Mexican Infants
Randomized, doble blind, clinical, controlled trial aimed to investigate the role of Lactobacillus reuteri DSM 17938 in the prevention of gastrointestinal and respiratory tract infections in mexican children who attend day care…
- Trial name
- NCT01249911
- Testing
- Lreuteri
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- National Institute of Pediatrics, Mexico
Primary Spontaneous Pneumothorax (PSP), Conservative Management (Active Observation)
Conservative Management in Primary Spontaneous Pneumothorax: a Multicenter Randomized Non-inferiority Study
The goal of this randomized clinical trial is to find out whether a conservative management strategy (active observation without an initial invasive procedure) can treat as effectively as the standard treatment with chest tube…
- Trial name
- CONNEP (NCT07331805)
- Testing
- Conservative management (active observation), Chest tube drainage
- Volunteers
- 436 people
- Sponsor
- Corporacion Parc Tauli
Obesity, Diabetes
Comparison of Gastric By-Pass and Optimized Medical Treatment in Obese Diabetic Patients
The objectives are to compare the results of the Gastric By-Pass (GBP) to that of optimized medical therapy in patients with obesity and poorly controlled type 2 diabetes in terms of mortality, weight loss, glycemic control…
- Trial name
- DIABSURG (NCT01501201)
- Testing
- Gastric By-Pass, optimized medical management
- Where
- 10 sites in France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Lille
Rotator Cuff Tear
Operative Versus Non-operative Management of Rotator Cuff Tear
This study aims at determining the effectiveness and cost-effectiveness of surgical management of full-thickness rotator cuff tears compared to conservative treatment.
- Trial name
- NCT00695981
- Testing
- Rotator cuff repair, Conservative treatment
- Where
- 3 sites in Finland
- Volunteers
- 100 people
- Sponsor
- Central Finland Hospital District
Chest Pain, Coronary Artery Disease
Study of Value of Cardiac PET Scans With or Without CT Angiography and/or Measurement of Coronary Flow Reserve
How does PET myocardial perfusion imaging involving CT angiography and measurement of coronary flow reserve affect patient care.
- Trial name
- NCT00669968
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Kettering Health Network
Bladder Cancer
Cost-Effectiveness in Bladder Cancer
This randomized clinical multicentre trial aims to evaluate the efficacy of microsatellite analysis on voided urine to detect tumour recurrences in the follow-up of patients with superficial urothelialcell carcinoma (UCC).
- Trial name
- NCT00126958
- Testing
- urinary analysis
- Volunteers
- 500 people
- Sponsor
- Erasmus Medical Center
Pneumonia, Primary Health Care
Tools for the Integrated Management of Childhood Illness (TIMCI): Evaluation of Pulse Oximetry & Clinical Decision Support Algorithms in Primary Care
By introducing pulse oximetry, with or without clinical decision support algorithms, to primary care facilities in India, Kenya, Senegal and Tanzania, the Tools for Integrated Management of Childhood Illness (TIMCI) project aims…
- Conditions
- Pneumonia, Primary Health Care, Child Health, Hypoxia
- Trial name
- TIMCI (NCT04910750)
- Testing
- Pulse oximetry, Clinical Decision Support Algorithm
- Where
- 27 sites in Tanzania
- Volunteers
- 167,517 people
- Sponsor
- Swiss Tropical & Public Health Institute
Endotracheal Tube, Nasogastric Tube
AI-Assisted Chest X-Ray for Misplaced Endotracheal and Nasogastric Tubes and Pneumothorax in Emergency and Critical Care Settings
Background Advancements in artificial intelligence (AI) have driven significant breakthroughs in computer-aided detection (CAD) for chest X-ray imaging.
- Conditions
- Endotracheal Tube, Nasogastric Tube, Pneumothorax
- Trial name
- NCT06842043
- Testing
- AI-assisted model
- Where
- Taiwan
- Volunteers
- 10,900 people
- Sponsor
- National Taiwan University Hospital
Self-Injurious Behavior
The (Cost-) Effectiveness of Mindfulness-training and Cognitive Behavioural Therapy in Adolescents and Young Adults With Deliberate Self Harm
Background: In recent years, there has been a marked rise in the frequency of young people engaging in Deliberate Self-Harm (DSH). DSH refers to all kinds of self-harming behaviour, with and without suicidal intent.
- Trial name
- DSH (NCT00694668)
- Testing
- Cognitive Behavioral treatment, Mindfulness based cognitive therapy
- Where
- 3 sites in Netherlands
- Volunteers
- 84 people
- Sponsor
- Leiden University Medical Center
Kidney Disease, Chronic, Transplant Recipient (Kidney)
Effectiveness and Cost-effectiveness of a Pre-emptive Genotyping Strategy in Patients Receiving Tacrolimus
This is a phase IV multicentre adaptive single-blinded randomized clinical trial to evaluate if preemptively genotyping populations at pretransplant chronic kidney disease susceptible of receiving tacrolimus therapy is effective…
- Conditions
- Kidney Disease, Chronic, Transplant Recipient (Kidney), Immunosuppression
- Trial name
- TRANSPGx (NCT06701825)
- Testing
- Tacrolimus
- Where
- Spain
- Volunteers
- 114 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Diabetes Mellitus
Improving Diabetes Care:Effectiveness of Physician Profiling and Care Coordination by a Diabetes Resource Nurse
The purpose of this study is to test the effectiveness of physician profiling and care coordination by a diabetes resource nurse in improving the quality of diabetes care.
- Trial name
- NCT00258674
- Testing
- Medicare Claims Feedback, Medical Record Review, Diabetes Resource Nurse
- Where
- United States
- Volunteers
- 1,891 people
- Sponsor
- Baylor Research Institute
Alcohol Consumption
Project SHARE (Senior Health and Alcohol Risk Education)
Older adults become more sensitive to alcohol, and alcohol also interacts adversely with their common medical conditions and medications.
- Trial name
- NCT00107640
- Testing
- Patient-provider education
- Where
- United States
- Volunteers
- 1,186 people
- Sponsor
- University of California, Los Angeles
Diverticulitis
Diverticulitis: Antibiotics or Close Observation?
Rationale The prevalence of colonic diverticular disease is increasing in Western countries. Approximately 10 to 25% of patients with diverticular disease will eventually develop an episode of acute diverticulitis.
- Trial name
- DIABOLO (NCT01111253)
- Testing
- Amoxicillin-clavulanate
- Where
- 24 sites in Netherlands
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Moderate Acute Malnutrition
Modified Dosage for Moderate Acute Malnutrition (MODAM-MAM)
Protocols for the community-based management of acute malnutrition (CMAM) have not changed significantly for more than 20 years, with relatively complex treatment protocols and persistent supply chain challenges that have limited…
- Trial name
- MODAM-MAM (NCT06056089)
- Testing
- ready-to-use supplementary food (RUSF), ready-to-use therapeutic food (RUTF)
- Where
- 3 sites in Ethiopia
- Volunteers
- 2,400 people
- Sponsor
- Action Against Hunger USA
Somatization Disorder
Treatment of Patients With Longstanding Unexplained Health Complaints
The purpose of this study is to determine the effect of specialized treatment (including cognitive therapy, social counselling and a recommendation letter to the patients' primary care physician) on the functional level…
- Trial name
- NCT00132197
- Testing
- Cognitive Behavioral Therapy, Recommendation of care (letter to general practitioner [GP])
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- University of Aarhus
First Aid Training, Adolescent
PRECEDE-PROCEED BASED FIRST AID TRAINING: SELF-EFFICACY, SKILL AND COST ANALYSIS IN HIGH SCHOLL STUDENTS
This research has two objectives. Firstly, to determine the effect of a first aid training program, developed based on the PRECEDE-PROCEED model, on the first aid knowledge, self-efficacy, and skill levels of high school…
- Conditions
- First Aid Training, Adolescent, School Health
- Trial name
- NCT07770503
- Testing
- First aid training program developed based on the PRECEDE-PROCEED model., control group
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Health, Subjective, Cost Effectiveness
Effects of Patient-centered Telephone Education in Day Surgery
This study describe and evaluate the effectiveness of patient-centered telephone education in day surgery. The aim is to evaluate the effects of patient-centered telephone education on the experienced health of adult patients and…
- Trial name
- NCT03549403
- Testing
- Patient-centered telephone education
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Inflammatory Bowel Diseases, Crohn Disease
Cost-effectiveness of TPMT Pharmacogenetics
The purpose of this study is to determine whether thiopurine S-methyltransferase (TPMT) genotyping prior to thiopurine use is cost-effective in patients with inflammatory bowel disease (IBD) in need of immune suppression.
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- TOPIC (NCT00521950)
- Testing
- TPMT genotyping; Drug: azathioprine or 6-mercaptopurine, azathioprine (AZA) or 6-mercaptopurine (6-MP)
- Where
- 3 sites in Netherlands
- Volunteers
- 853 people
- Sponsor
- ZonMw: The Netherlands Organisation for Health Research and Development
Arhythmia
Comparison and Analysis of Functionality, Safety, Cost-effectiveness, and Environmental Impact of Reprocessed and New Ablation Catheters in Electrophysiological Procedures.
This study evaluates whether re-sterilized (reprocessed) ablation catheters are as effective and safe as new ablation catheters when used for electrophysiological procedures.
- Trial name
- RE-USE EP (NCT07522424)
- Testing
- Ablation - new, Ablation - reprocessed
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- Ivan Zeljkovic
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