Clinical trials: Cost-Effectiveness
Newborn Hypothermia
Efficacy of Celsi Warmer for the Management of Hypothermic Newborns
The purpose of the study is to evaluate the efficacy of a novel low-cost warming device to provide thermal care for newborn babies with hypothermia in low-resource hospitals.
- Trial name
- NCT06000826
- Testing
- Celsi Warmer
- Where
- Tanzania
- Volunteers
- 90 people
- Sponsor
- William Marsh Rice University
Parkinson Disease
Multidisciplinary Home-based Tele-rehabilitation Intervention
Falls in Parkinson's Disease (PD) are very frequent with often devastating consequences, increasing comorbidity, mortality, decreased quality of life and increased socio-health costs.
- Trial name
- TeleFall (NCT04694443)
- Testing
- Multidisciplinary tele-health intervention (physical therapy, neurologist, nurse, psychologist), Standard in-office medical care
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Esther Cubo
Rotator Cuff Injuries, Shoulder Pain
Cost-Effectiveness of Rotator Cuff Repair Methods
Shoulder pain is one of the most common musculoskeletal complaints in orthopedic practice. Rotator cuff injuries account for up to 70% of pain in the shoulder girdle.
- Conditions
- Rotator Cuff Injuries, Shoulder Pain, Shoulder Impingement, Shoulder Injuries
- Trial name
- NCT04146987
- Testing
- Rotator cuff repair surgery
- Where
- 2 sites in Brazil
- Volunteers
- 100 people
- Sponsor
- Hospital Israelita Albert Einstein
Fever, Malaria
Parasite-based Diagnosis for Malaria in Uganda: Feasibility and Cost-Effectiveness
The purpose of this study is to compare the cost-effectiveness of treating malaria based on three methods of diagnosis (rapid test, microscopy and presumptive diagnosis) among patients attending level three government health…
- Trial name
- NCT00565071
- Testing
- Field microscopy and Paracheck Pf®
- Where
- Uganda
- Volunteers
- 102,087 people
- Sponsor
- Makerere University
Anesthetic Gas Consumption and Cost-Effectiveness
Comparison of Different Ventilator and Vaporizer Technologies to Study Economic and Environmental Implications
The purpose of this study is to test whether or not the use of a low volume ventilator in an anesthesia machine reduces anesthetic costs significantly as compared to other high volume machines.
- Trial name
- NCT04851314
- Testing
- ICU certified ventilator, Non-ICU certified ventilator
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of California, Irvine
Organ Transplantation, Immunosuppressive Agents
Immunosuppressants to Postoperative Infection and Death
The goal of this observational study is to explore the different immunosuppressive agents and related outcomes in organ transplantation patients in Taiwan.
- Conditions
- Organ Transplantation, Immunosuppressive Agents, Cohort Study
- Trial name
- NCT06121804
- Testing
- Immunosuppressive Agents
- Where
- Taiwan
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Nonfunctioning Kidney, Renal Cell Carcinoma (RCC)
Laparoscopic Versus Open Nephrectomy : Clinical Effectivness and Cost Analysis
To evaluate and compare clinical effectiveness (operative time, blood loss, hospital stay, complications and etc) and cost analysis' between laparoscopic nephrectomy and open nephrectomy .
- Trial name
- NCT07461090
- Testing
- open or laparoscopic nephrectomy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Anemia, Inflammation
Frequent Dosing of CERA Improves Nutrition and Inflammation in Hemodialysis Patients
The response of Continuous Erythropoietic Receptor Activator (CERA) with different dose interval and the survey for influence factors: We aim to evaluate a better clinical response which can be achieved by different dosing…
- Conditions
- Anemia, Inflammation, Malnutrition
- Trial name
- NCT02232113
- Testing
- CERA
- Where
- Taiwan
- Volunteers
- 67 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Sepsis, Severe Sepsis
Protocolized Care for Early Septic Shock
The ProCESS study is large, 5-year, multicenter study of alternative resuscitation strategies for septic shock. The study hypothesizes that there are "golden hours" in the initial management of septic shock where prompt…
- Conditions
- Sepsis, Severe Sepsis, Septic Shock
- Trial name
- ProCESS (NCT00510835)
- Testing
- Early Goal Directed Therapy (EGDT), Protocolized Standard Care (PSC), Usual Care (UC)
- Where
- 31 sites in United States
- Volunteers
- 1,351 people
- Sponsor
- University of Pittsburgh
Sarcopenia
Prevalence and Effect of Lifestyle Modification on Clinical Outcomes and Cost-effectiveness Ratio for Sarcopenia
The purposes of this study were to investigate the prevalence and risk factors for sarcopenia in Chinese adults and elderly, and evaluate the effect of Lifestyle Modification Project (LMP) on Clinical Outcomes, Quality of Life…
- Trial name
- NCT02873676
- Testing
- nutritional intervention, resistance training program, lifestyle modification project
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Constipation - Functional, Constipation-predominant Irritable Bowel Syndrome
MOWOOT Device Treatment for Adults With Chronic Constipation
The primary objective is to compare the effectiveness of the experimental Intermittent Colonic Exoperistalsis (ICE) treatment with MOWOOT, with the active control of trans-anal irrigation (TAI) as standard-of-care.
- Conditions
- Constipation - Functional, Constipation-predominant Irritable Bowel Syndrome, Constipation Chronic Idiopathic, Constipation; Neurogenic
- Trial name
- MOTACC (NCT04666155)
- Testing
- Intermittent Colonic Exoperistalsis with MOWOOT device, Standard of care with Trans-Anal Irrigation
- Where
- 3 sites in United Kingdom
- Volunteers
- 86 people
- Sponsor
- usMIMA S.L.
Heart Failure, Coronary Artery Disease
Same Day Discharge (SDD) After Implantable Cardioverter Defibrillator (ICD) Implant
The purpose of this study is to determine whether it is safe to send patients home from the hospital on the same day following an implantable cardioverter defibrillator (ICD) implant.
- Trial name
- SDD for ICD (NCT01993862)
- Testing
- Same Day Discharge
- Where
- 28 sites in United States
- Volunteers
- 266 people
- Sponsor
- Abbott Medical Devices
Multiple Sclerosis
Home-Based Exergame Rehabilitation for Upper Limb Function in People With Multiple Sclerosis
This randomized pilot clinical trial aims to evaluate the effectiveness, feasibility, and cost-effectiveness of a semi-autonomous upper-limb rehabilitation program based on therapeutic exergames in people with Multiple Sclerosis…
- Trial name
- NCT07430462
- Testing
- Exergame-Based Upper Limb Rehabilitation Program, Conventional Home-Based Physiotherapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Marina Castel Sánchez
Atrial Fibrillation
Comparison of External Event Recorders for Atrial Fibrillation Monitoring
Ablation of atrial fibrillation is a well established treatment method to restore normal sinus rhythm and eliminate the need for continued antiarrhythmic therapy and anticoagulation.
- Trial name
- NCT00863382
- Testing
- Standard Event Monitor, Sleuth Monitor
- Where
- United States
- Sponsor
- Dhanunjaya Lakkireddy, MD, FACC
Pyeloplasty, Complications of Surgical Procedures or Medical Care
Cost-Effectiveness and Clinical Outcomes of Double J Stent Versus Percutaneous Feeding Tube Placement Following Open Pyeloplasty in Pediatric Patients: A Prospective Randomized Single-center Study
Open pyeloplasty is a common surgical intervention for pediatric patients with ureteropelvic junction obstruction. Post-operative management strategies, including the use of a double J stent and a percutaneous feeding tube, vary…
- Conditions
- Pyeloplasty, Complications of Surgical Procedures or Medical Care, Hospital Stay
- Trial name
- DJS (NCT06847841)
- Testing
- Double J Stent Placement, Percutaneous Feeding Tube Placement
- Where
- Pakistan
- Volunteers
- 140 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Keratosis, Actinic
IM Versus 5-FU Versus IMI Versus MAL-PDT in Treatment of Actinic Keratosis
A multi-centre randomised controled single blind clinical phase IV trial with the aim to determine the most effective treatment in terms of lesion reduction, costs and patient satisfaction in treatment of actinic keratosis (AK)…
- Trial name
- Akti (NCT02281682)
- Testing
- Imiquimod, 5-fluorouracil, Ingenol mebutate
- Where
- Netherlands
- Volunteers
- 624 people
- Sponsor
- Maastricht University Medical Center
Depression - Major Depressive Disorder
EEG Prediction and Clinical Efficacy of tDCS in Major Depression
The purpose of this randomized controlled trial is to investigate the non-inferiority, and possible superiority, of a high-dose home-based tDCS protocol compared with a conventional home-based protocol, and to assess its…
- Trial name
- DM-TDCS-PREDIC (NCT07611773)
- Testing
- High-dose home-tDCS, Conventional home-tDCS
- Where
- Spain
- Volunteers
- 270 people
- Sponsor
- Ionclinics & Deionic SL
PTSD, Sleep Disorder
Stepping Together for Children After Trauma, Norway
The goal of this randomized controlled trial is to learn about how to effectively help children (aged 7-12) who have developed moderate symptoms of posttraumatic stress after exposure to trauma, and prevent development of more…
- Conditions
- PTSD, Sleep Disorder, Depressive Symptoms, Quality of Life
- Trial name
- NorStep (NCT05734547)
- Testing
- Stepping Together for Children after Trauma (ST-CT), Usual care
- Where
- 2 sites in Norway
- Volunteers
- 160 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Human Papilloma Virus
Single Visit Clinical Validation of ScreenFire, a Low-cost HPV Test
The purpose of this study is to validate a new low-cost, self-collected HPV screening test (ScreenFire) and compare it to the standard provider collected careHPV, for the detection of high grade cervical cancer.
- Trial name
- SCALE (NCT05431699)
- Testing
- ScreenFire HPV test, careHPV test, Colposcopy and biopsy
- Where
- El Salvador
- Volunteers
- 9,100 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Stable Angina, Coronary Artery Disease
CCTA, CACS and ECG Stress Testing in Patients With Suspected CAD: Precision Phenotyping and Financial Evaluation
The "DATASET-PRECISE", a 3-arm parallel randomized study, aims to provide new insights in risk stratification of patients with suspected CAD in the Greek population.
- Conditions
- Stable Angina, Coronary Artery Disease, Atherosclerosis, Coronary Artery Calcification
- Trial name
- DATASET (NCT04424121)
- Testing
- CCTA
- Where
- 3 sites in Greece
- Volunteers
- 900 people
- Sponsor
- Aristotle University Of Thessaloniki
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.