Clinical trials: Cost-Effectiveness
Cyanide Poisoning
Hydroxycobalamin and Rural Emergency Medical Services Cyanide Exposure Patients: A Cost Analysis
The costs to a rural emergency medical services (EMS) system of a change from a traditional cyanide antidote kit to a kit containing hydroxocobalamin alone are currently unknown.
- Trial name
- NCT01656616
- Testing
- Cyanide antidote administration
- Where
- United States
- Sponsor
- MaineHealth
Physical Inactivity, Sedentary Behavior
Cost-effectiveness, Impact of a Workplace-based Intervention to Reduce Occupational Sitting Time in Office-based Workers
The purpose of this study is to examine the impact and cost effectiveness of a workplace-based intervention aimed at reducing prolonged occupational sitting among office-based workers. The study will be conducted in three phases.
- Conditions
- Physical Inactivity, Sedentary Behavior, Occupational Diseases, Physical Activity
- Trial name
- ISKE (NCT06149364)
- Testing
- ISKE
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Metopic Synostosis
Comparing Conservative to Surgical Treatment of Trigonocephaly Craniofacial Surgery in Children With Trigonocephaly: an Observational Cohort Study on Clinical Outcomes, Psychosocial Wellbeing, and Costs
RESEARCH QUESTION Is the effectiveness of conservative policy comparable to that of surgery in children with trigonocephaly, with regard to clinical outcomes and psychosocial functioning, stress for parents, and costs? DESIGN…
- Trial name
- Treat Trigono (NCT06069479)
- Testing
- craniofacial surgery
- Where
- Netherlands
- Volunteers
- 440 people
- Sponsor
- Erasmus Medical Center
Chest Pain, Coronary Heart Disease Risk
Comparison of the Cost-Effectiveness of Coronary CT Angiography Versus Myocardial SPECT in Patients With Intermediate Risk of Coronary Heart Disease
The investigators aim to compare the cost-effectiveness of CCTA and myocardial SPECT in patients with intermediate pre-test probability of CHD.
- Trial name
- CARE-CCTA (NCT01542086)
- Testing
- Myocardial SPECT, 64-channel coronary CT angiography (CCTA)
- Where
- South Korea
- Volunteers
- 1,050 people
- Sponsor
- Seoul National University Hospital
Abortion Rate
Post Abortion IUD & Recurrent Abortion 2001-2004
It has been shown that the immediate insertion of intrauterine devices (IUDs) post-abortion prevents repeat abortions. The researchers hypothesize that providing free IUDs post-abortion will be associated with a lower rate of…
- Trial name
- NCT00965770
- Testing
- Intrauterine device (IUD)
- Where
- Canada
- Volunteers
- 1,101 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Depression
Lifestyle Modification Program in the Prevention and Treatment of Depression
Introduction: Major depression is a highly prevalent pathology that is currently the second most common cause of disease-induced disability in our society.
- Trial name
- NCT03951350
- Testing
- Lifestyle Modification Program (LMP), Lifestyle Modification Program (LMP) + Information Communication Technologies (ICTs)
- Where
- Spain
- Volunteers
- 159 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Pain, Chronic, Cancer Pain
Telemedicine Versus In-Person Follow-up for Cancer Pain Management: An Equity and Cost Analysis Comparison Using a Prospective Quasi-Experimental Design
Cancer is the second leading cause of death worldwide, with approximately 18.1 million new cases and 9.6 million deaths reported in 2018.
- Conditions
- Pain, Chronic, Cancer Pain, Cancer Related Pain
- Trial name
- NCT05628246
- Testing
- Telemedicine, In-person
- Where
- Thailand
- Volunteers
- 193 people
- Sponsor
- Mahidol University
Cardiogenic Shock, Myocardial Infarction
Clinical Outcome and Cost-effectiveness of Reduced Noradrenaline by Using a Lower Blood Pressure Target in Patients With Cardiogenic Shock From Acute Myocardial Infarction
Rationale: Pump failure due to acute myocardial infarction (AMI) can lead to cardiogenic shock (CS): a state of low blood flow to end-organs with subsequent multi-organ failure that is associated with high mortality rated.
- Trial name
- NORSHOCK (NCT05168462)
- Testing
- Reduced noradrenaline use
- Where
- Netherlands
- Volunteers
- 776 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Weight Loss
Cost-Effectiveness of Weight Loss Prevention in Nursing Homes: A Controlled Trial
Low oral food and fluid intake and unintentional weight loss are common problems among long-stay nursing home (NH) residents and are associated with adverse, costly clinical outcomes.
- Trial name
- NCT02567513
- Testing
- Supplement Intervention, Snack Intervention
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Asthma, Chronic Obstructive Pulmonary Disease
Effectiveness of Influenza Vaccine Reminder Systems
Influenza disease causes significant morbidity and mortality in the Unites States each year. Although influenza can cause morbidity in otherwise healthy individuals, adults with chronic lung disease have significantly increased…
- Trial name
- NCT01852656
- Testing
- Postcard and IVR Reminder Group, Postcard Only Reminder Group, IVR Only Reminder Group
- Where
- United States
- Volunteers
- 12,255 people
- Sponsor
- Kaiser Permanente
DGBI, Depression/Anxiety
Feasibility and Acceptability of an Online ACT Intervention for Disorders of Gut-Brain Interaction
The goal of this clinical trial is to assess the acceptability, feasibility, and usability of the iACTforDGBI intervention among patients with Disorders of Gut-Brain Interaction (DGBI).
- Trial name
- iACTforDGBI (NCT06887751)
- Testing
- Acceptance and Commitment Therapy (ACT), Psychoeducation
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Örebro University, Sweden
HIV, Viral Hepatitis
A Cost Effective and Time Saving Blood Test to Detect Six Human Bloodborne Infectious Diseases
The consortium will develop a new in vitro diagnostic (IVD) test to screen donated blood for bloodborne infectious pathogens, saving blood banks time and costs required for analysis of mandatory pathogens.
- Trial name
- SAFE-Blood (NCT04304612)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Montpellier
Cerebral Palsy (CP)
Optimized AFO Care For Children With Cerebral Palsy.
Ankle-foot orthoses (AFOs) are widely prescribed in children with cerebral palsy (CP) to improve their gait, enhance mobility and prevent secondary complications during growth.
- Trial name
- OPTI-CARE (NCT07811336)
- Testing
- Optimized AFO care
- Where
- Netherlands
- Volunteers
- 86 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Stroke
Interdisciplinary Team Approach to Stroke Rehabilitation in Home Care
As the population ages and the number of stroke survivors increases, information is needed to determine the best way of providing home care services for rehabilitation to stroke survivors and their caregivers while containing…
- Trial name
- NCT00463229
- Testing
- Interprofessional Team Approach
- Where
- Canada
- Volunteers
- 101 people
- Sponsor
- McMaster University
Smoking
Implementing Tobacco Control in Dental Practice
Our goal is to test a dentist-hygienist team intervention to help dental patients quit smoking and determine if it can be effectively and cost-effectively implemented and sustained.
- Trial name
- NCT00297700
- Testing
- Active referral
- Where
- United States
- Volunteers
- 2,800 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cannabis Use Disorder
Rewards for Cannabis Abstinence-study
The goal of this clinical trial is to investigate the (cost-)effectiveness of contingency management (CM) compared with Cognitive Behavioural Therapy (CBT) for the treatment of cannabis use disorder (CUD) in youth (16-22 years).
- Trial name
- RECAB (NCT05836207)
- Testing
- Abstinence-focused Contingency Management (CM) - stand alone, Standard Outpatient Cognitive Behavioural Therapy (CBT)
- Where
- 5 sites in Netherlands
- Volunteers
- 154 people
- Sponsor
- Parnassia Addiction Research Centre
Parkinson Disease
Cue2Walk, Cost-effectiveness of Automated Freezing Detection and Provision of External Cues in Comparison to Usual Care in People With Parkinson's Disease
The majority of people with Parkinson's disease incur Freezing of Gait (FoG), which is not addressed adequately by medication. Cueing is a proven strategy to overcome FoG.
- Trial name
- NCT06416345
- Testing
- Cue2Walk, Usual Care
- Where
- 2 sites in Netherlands
- Volunteers
- 84 people
- Sponsor
- Amsterdam UMC, location VUmc
Critical Limb Ischemia
Prospective Observation Study of Outcome of Interventions for Critical Ischemia
Severe atherosclerosis in the leg arteries is termed critical limb ischemia (CLI). This condition gives great suffering for the patients in terms of pain, wounds and often developing gangrene.
- Trial name
- PROVENCE (NCT01794494)
- Testing
- Bypass surgery, Endovascular recanalization
- Where
- Sweden
- Volunteers
- 190 people
- Sponsor
- Sahlgrenska University Hospital
Stress Urinary Incontinence
Value of Urodynamics Prior to Stress Incontinence Surgery
To test the value of preoperatively performed urodynamics with regard to outcome of surgery for stress urinary incontinence (SUI) and to examine whether not performing urodynamics preoperatively is more cost effective than…
- Trial name
- VUSIS (NCT00509730)
- Testing
- Urodynamics
- Where
- Netherlands
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Physical Activity
Testing Adaptive Interventions to Improve Physical Activity for Sedentary Women
This study employs a Sequential Multiple Assignment Randomized Trial (SMART) and aims to determine the most effective adaptive intervention combining four efficacious treatments (enhanced physical activity monitor, motivational…
- Trial name
- NCT03558828
- Testing
- Step 1: PA Monitor, Step 1: PA Monitor + Text, Step 2: PA Monitor with Calls
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
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