Clinical trials: Cost-Effectiveness
Atrial Fibrillation
Comparison of External Event Recorders for Atrial Fibrillation Monitoring
Ablation of atrial fibrillation is a well established treatment method to restore normal sinus rhythm and eliminate the need for continued antiarrhythmic therapy and anticoagulation.
- Trial name
- NCT00863382
- Testing
- Standard Event Monitor, Sleuth Monitor
- Where
- United States
- Sponsor
- Dhanunjaya Lakkireddy, MD, FACC
Colorectal Cancer
The Effect of a Virtual Navigator on Colorectal Cancer Patient Empowerment
For individuals diagnosed with colorectal cancer, exposure to up-to-date cancer information and support as well as guidance to access the most appropriate health care services is crucial for cancer self-management and support.
- Trial name
- NCT01549327
- Testing
- Oncology Interactive Navigator, Routine Care
- Where
- 4 sites in Canada
- Volunteers
- 129 people
- Sponsor
- McGill University
Asthma
REALL: A Retrospective Observational Study to Compare the Effectiveness and Cost-Effectiveness Between Different Step-3 Asthma Treatment Strategies
This is a retrospective observational study utilising anonymised individual patient clinical and prescribing information routinely collected by UK General Practitioners (GPs).
- Trial name
- REALL (NCT00628563)
- Where
- United Kingdom
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Cerebrovascular Disorders, Smoking Cessation
Efficacy and Cost-Effectiveness of Cost-free Pharmacotherapy for Smoking Cessation for High-risk Smokers With Cerebrovascular Disease
Research Aims The aims of this research study are to determine whether cost-free smoking cessation pharmacotherapy: 1. Helps smokers with Transient Ischemic Attack (TIA) or stroke to quit smoking over the long-term, compared to…
- Trial name
- NCT00962988
- Testing
- Cost-Free Pharmacotherapy Group, Prescription Only Group
- Where
- 2 sites in Canada
- Volunteers
- 194 people
- Sponsor
- Ottawa Heart Institute Research Corporation
HIV Infection
BASTA Study on STI in HIV Infected Patients
This is a single center, independent study. The primary objective is to compare efficacy and safety of continuing a conventional HAART in chronically infected HIV patients with a therapeutic strategy based on long term…
- Trial name
- NCT00310245
- Testing
- STI (structured Treatment Interruption)
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Obesity, Obese
Cost-effectiveness Study of a Multidisciplinary Weight Loss Method to Improve the Health Condition of Obese Patients
Prospective, observational, multicenter study based on a registry of patients with obesity and associated comorbidities undergoing a standardized multidisciplinary weight loss method with a 2-year follow-up.
- Trial name
- PRONOCOST (NCT05833464)
- Where
- Argentina
- Sponsor
- Protein Supplies SL
Neoplasms
Personalized Live-remote Exercise Training for Cancer Survivors
Background Many people with cancer face ongoing problems from their disease and treatments, like fatigue, reduced physical fitness, feeling anxious or down, and neuropathy.
- Trial name
- LION (NCT06270628)
- Testing
- Exercise group
- Where
- Netherlands
- Volunteers
- 350 people
- Sponsor
- UMC Utrecht
Fibromyalgia Syndrome
Cost-utility and Biological Underpinnings of MBSR in Fibromyalgia Syndrome
Purpose: Fibromyalgia syndrome (FMS) is a disabling condition mainly characterized by chronic widespread pain, disturbed sleep, fatigue, and distress.
- Trial name
- EUDAIMON (NCT02561416)
- Testing
- MBSR, FibroQol, TAU
- Where
- Spain
- Volunteers
- 225 people
- Sponsor
- Fundació Sant Joan de Déu
Dental Caries in Children
Cost-effectiveness of Topical Fluoride in Preventing Deciduous Dental Caries in Preschool Children
Fluoride foam and fluoride varnish are effectiveness in prevention deciduous dental caries. However, the relative clinical efficacy and cost-effectiveness of these two interventions are uncertain.
- Trial name
- NCT05025163
- Testing
- 1.23% fluoride foam application, 2.26% fluoride varnish application
- Volunteers
- 1,083 people
- Sponsor
- National Center for Chronic and Noncommunicable Disease Control and Prevention, China CDC
Soft Tissue Injuries
Cost-effectiveness of Two Painkillers for Treating Pain After Limb Injuries
Background: Paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen are commonly used oral analgesics in emergency departments (ED) not only in Hong Kong but throughout the world.
- Trial name
- NCT00528658
- Testing
- Paracetamol, Ibuprofen
- Where
- Hong Kong
- Volunteers
- 782 people
- Sponsor
- Chinese University of Hong Kong
Atrial Flutter
Catheter Ablation as the First Line Therapy for Typical Atrial Flutter
Catheter ablation of typical atrial flutter is a well established technique with a high acute success rate and very low complication and recurrence rates.
- Trial name
- NCT00213408
- Testing
- Radiofrequency catheter ablation of typical atrial flutter
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Rouen
Cervical Cancer
Exploring the Efficacy, Safety and Cost-effectiveness Analysis of Cadonilimab in the Treatment of Cervical Cancer
Cadonilimab, a PD-1/CTLA-4 bi-specific antibody, is being developed by Akeso, Inc. for the treatment of a range of solid tumors, including cervical cancer, lung cancer, gastric/gastroesophageal junction cancer, liver cancer and…
- Trial name
- NCT06140589
- Testing
- Cadonilimab
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fujian Cancer Hospital
Inguinal Hernia
The (Cost-) Effectiveness of Paediatric Laparoscopic Hernia Repair Compared to Open Hernia Repair
This study assess the (cost-)effectiveness of open versus laparoscopic Percutaneous Inguinal Ring Suturing (PIRS) technique for unilateral inguinal hernia repair in children aged 0-16 years.
- Trial name
- HERNIIA-2 (NCT06451432)
- Testing
- Percutaneous Inguinal Ring Suturing (PIRS) technique
- Where
- 9 sites in Netherlands
- Volunteers
- 464 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Post-Acute-Stroke Rehabilitation
Effectiveness of a Wearable Device-based Assisted Post-stroke Rehabilitation System
Multidisciplinary rehabilitation facilitates functional recovery after stroke, and adherence to rehabilitation guidelines is associated with improved outcomes.
- Trial name
- NCT04997408
- Testing
- Customized exercise app, In-person therapist-supervised rehabilitation
- Volunteers
- 140 people
- Sponsor
- Landseed Hospital
Interstitial Lung Disease
Cost-effectiveness Analysis of Three Corticosteroids in ILDs
This was a 3 months prospective, open label, and parallel study to test the efficacy of 3 different corticosteroids in the management of interstitial lung diseases.
- Trial name
- NCT04982809
- Testing
- Betamethasone, Dexamethasone, Prednisolone
- Where
- Egypt
- Volunteers
- 107 people
- Sponsor
- Cairo University
UTERINE CERVICAL NEOPLASMS, ENDOMETRIAL NEOPLASMS
Cost-Effectiveness and Patients Satisfaction of Conventional vs Robotic-Assisted Laparoscopy in Gynecologic Oncologic Indications
Laparoscopic surgery is gaining currency in the field of oncologic care, particularly for colorectal and gynecologic cancers. This innovation could be used either for staging purpose and therefore could steer global therapeutic…
- Trial name
- NCT02865889
- Testing
- Laparoscopy in Gynecologic Oncologic Indications, Conventional surgery (abdominal radical surgery)
- Where
- France
- Volunteers
- 343 people
- Sponsor
- Institut Paoli-Calmettes
Hemorrhoids, Fissure in Ano
Multi-Drug Analgesia vs. Standard Solution for Anal Surgery
The primary aim is to test the magnitude and duration of analgesia provided by single dose multi-drug analgesia administered for perianal block, and compare with standard solution (Marcaine \& Lidocaine in 1:1 mixture - Total 60…
- Conditions
- Hemorrhoids, Fissure in Ano, Fistula;Rectal
- Trial name
- NCT03105674
- Testing
- Multi-drug local anesthetics (Combination), Standard local anesthetics (Combination)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Thromboses, Deep Vein, Surgery--Complications
Thromboprophylaxis in Patients Undergoing Orthopedic Surgeries; Comparison Between Rivaroxaban and Enoxaparin
The main objective is to reduce the incidence of venous thromboembolism (VTE) in orthopedic postoperative patients based on the potential benefit of using rivaroxaban as a monotherapy.
- Trial name
- NCT03299296
- Testing
- Rivaroxaban 10 Milligrams, Enoxaparin 40 Milligrams/0.4 Milliliters Prefilled Syringe
- Volunteers
- 100 people
- Sponsor
- Ahmed AbdelMoneim Hassan Ali
Diabetes Mellitus, Type 2
Dulce Digital-Me: An Adaptive mHealth Intervention for Underserved Hispanics With Diabetes
This study will compare Dulce Digital (i.e., the investigators' proven-effective combination of "one-size-fits-all" educational text messages and nurse monitoring of patient-transmitted blood glucose values) and Dulce Digital-Me…
- Trial name
- DD-Me (NCT03130699)
- Testing
- Dulce Digital, Dulce Digital-Me (Automated Delivery), Dulce Digital-Me (Medical Assistant)
- Where
- 2 sites in United States
- Volunteers
- 310 people
- Sponsor
- Scripps Whittier Diabetes Institute
Proton Pump Inhibitor, Primary Care
Proton Pump Inhibitors (PPI): a Study to Improve Appropriate Prescriptions in the Elderly
Proton Pump Inhibitors(PPIs) are the leading evidence-based therapy for upper gastrointestinal disorders and prevention of antiplatelet or non-steroidal anti-inflammatory drugs induced ulcer.
- Trial name
- LAPTOP-PPI (NCT04637750)
- Testing
- Educational intervention
- Where
- 3 sites in Italy
- Volunteers
- 800 people
- Sponsor
- Mario Negri Institute for Pharmacological Research