Clinical trials: Cost-Effectiveness
HIV
Assisted Partner Notification to Augment HIV Treatment and Prevention in Kenya
The main purpose of this implementation science study is to find out if providing aPS at 18 different Ministry of Health (MOH) VCT clinics in Kenya works and is cost-effective.
- Trial name
- APS (NCT01616420)
- Testing
- Assisted-partner notification services
- Where
- 18 sites in Kenya
- Volunteers
- 2,424 people, healthy volunteers welcome
- Sponsor
- University of Washington
Coronary Arteriosclerosis, Myocardial Infarction
The Efficacy and Cost-Effectiveness of Behavioral Counseling for Exercise in Men and Women Following Acute Myocardial Infarction (AMI) and Percutaneous Coronary Intervention (PCI)
Purpose: The purpose of this project is to determine how effective the telephone-based counseling program is at helping patients with heart disease become more physically active.
- Trial name
- NCT00250913
- Testing
- Telephone-based physical activity counseling program
- Where
- Canada
- Volunteers
- 304 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Chronic Obstructive Pulmonary Disease, COPD Exacerbation
Testing a Prediction Algorithm Into a Running Telehealth System for Patients With COPD
This trial will test a COPD prediction algorithm into a telehealth system from the previous Danish large-scale trial, TeleCare North (NCT01984840).
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD Exacerbation, COPD Exacerbation Acute, COPD
- Trial name
- NCT05218525
- Testing
- Algorithm
- Where
- Denmark
- Volunteers
- 138 people
- Sponsor
- Aalborg University
Type 2 Diabetes Mellitus
Cost Effectiveness of Glargine Insulin Versus NPH Insulin
Glycemic control is fundamental in the management of diabetes mellitus .If lifestyle intervention and full tolerated doses of one or two oral glucose lowering drugs (OGLDs) fail to achieve or sustain glycemic goals, insulin…
- Trial name
- NCT01832935
- Testing
- insulin glargine, Insulin NPH
- Where
- Iran
- Volunteers
- 200 people
- Sponsor
- Tehran University of Medical Sciences
Hypertension
Effectiveness and Cost-Effectiveness of a Digital Care Pathway and Asynchronous Communication for Patients With Hypertension
The goal of this clinical trial is to learn if digital care pathway (DCP) and digital non-real-time messaging, in other words, asynchronous communication (AC) with nurse works to treat high blood pressure in adults in primary…
- Trial name
- DEPTH (NCT07812350)
- Testing
- Digital care pathway for hypertension, Asynchronous communication with nurse
- Where
- 6 sites in Finland
- Volunteers
- 600 people
- Sponsor
- Wellbeing Services County of Pirkanmaa
Dupuytren's Disease
Evaluation of Xiaflex: Trial of Effectivenss iN Dupuytren's
This is a prospective, multi-centre, pragmatic randomized controlled trial to compare both the clinical effectiveness and cost-effectiveness of collagenase injections (CI) versus limited palmar fasciectomy (LPF) to determine if…
- Trial name
- EXTEND (NCT02725528)
- Testing
- collagenase injection, limited palmar fasciectomy
- Where
- 10 sites in Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- McMaster University
Lung Cancer
Multimodal Prehabilitation in Thoracic Surgery
This trial aims to assess the impact of a multimodal prehabilitation program in high-risk patients undergoing lung resection surgery.
- Trial name
- NCT04052100
- Testing
- Usual care, Multimodal prehabilitation
- Where
- Spain
- Volunteers
- 158 people
- Sponsor
- Hospital Clinic of Barcelona
Obstructive Sleep Apnea (OSA)
Sleep Thermography for Diagnosis of Obstructive Sleep Apnea (TERMOAPNEA)
To assess the diagnostic validity and cost-effectiveness of an infrared thermography system in adults with clinical suspicion of Obstructive Sleep Apnea (OSA).
- Trial name
- TERMOAPNEA (NCT04206449)
- Testing
- Therapeutic decision PSG, Therapeutic decision Infrared thermgraphy system
- Where
- Spain
- Volunteers
- 198 people
- Sponsor
- Hospital Universitario Araba
Diabetic Retinopathy
The Cost-effectiveness of Screening for Diabetic Retinopathy in Hong Kong
Introduction: There is no debate that people with diabetes should be screened for the development of retinopathy which can threaten their sight. However, there is no routine screening for retinopathy in Hong Kong at present.
- Trial name
- NCT01628289
- Testing
- charging a co-payment for Diabetic Retinopathy screening, free screening without charging a co-payment
- Where
- 3 sites in China
- Volunteers
- 4,644 people
- Sponsor
- The University of Hong Kong
Partial Edentulism Class 3
Compare CAD/CAM Metallic RPD to Conventional Metallic RPD in Terms of Oral Health Related Quality of Life
Patients will be randomised to receive CAD/CAM metallic removable partial denture (RPD) followed by Conventional metallic RPD (Group A), or the opposite sequence (Group B), with a 3-month wear duration for each denture and…
- Trial name
- NCT06567262
- Testing
- CAD/CAM metallic removable partial denture, Conventional metallic removable partial denture
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Cairo University
Unhealthy Lifestyle of Persons With Mental Disorders
HEalth Promotion Intervention in MEntal Health Care
Overweight and obesity have become a serious global public health problem and the prevalence of these conditions is even higher among persons with mental disorders, compared with the general population.
- Trial name
- HEPIMEC (NCT01336946)
- Testing
- Psycho educational and behavioural group sessions, Walking session
- Where
- 25 sites in Belgium
- Volunteers
- 742 people
- Sponsor
- University Ghent
Burns
Impact of a Clinical Decision Algorithm on Length of Hospital Stay and Costs of Care of Burned Patients
Reliable and valid assessment of burn wound depth or healing potential is essential to treatment decision-making, to provide a prognosis, and to compare studies evaluating different treatment modalities.
- Trial name
- NCT03876340
- Testing
- Treatment algorithm, Current treatment
- Where
- Mexico
- Volunteers
- 44 people
- Sponsor
- Hospital Central "Dr. Ignacio Morones Prieto"
Status Asthmaticus
Effectiveness and Cost Study Comparing Two Ways to Deliver Albuterol for the Treatment of Asthma in the Hospital
This study will be conducted as a randomized, double blinded, controlled trial. The control group will receive albuterol delivered by a nebulizer along with placebo treatments delivered by a metered dose inhaler (MDI) with a…
- Trial name
- NCT00623688
- Testing
- Metered Dose Inhaler & Optichamber Advantage Valve Holding Chamber (VHC), Airlife Sidestream High Efficiency Nebulizer
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Akron Children's Hospital
Low Back Pain
Stratified Primary Care for Low Back Pain
The SPLIT project evaluates the implementation of a stratified model of care for people with low back pain patients who consulted primary care.This involves evaluating the process of implementation as well as patient level…
- Trial name
- SPLIT (NCT04046874)
- Testing
- Usual Care, SPLIT Stratified Model of Care
- Where
- Portugal
- Volunteers
- 175 people
- Sponsor
- Instituto Politécnico de Setúbal
Rare Disorders, Rare Diseases
AI-assisted Rare Disease Diagnosis
A multicentre randomised controlled trial evaluating whether a rare-disease diagnostic large language model can improve diagnostic quality, efficiency, and health-economic outcomes for physicians managing patients with suspected…
- Trial name
- NCT07650799
- Testing
- AI system
- Where
- 12 sites in China
- Volunteers
- 1,056 people
- Sponsor
- Peking Union Medical College Hospital
Breast Neoplasms, Musculoskeletal Pain
Hypnosis to Reduce Aromatase Inhibitor Pain and Improve Adherence
The purpose of this study is to determine whether hypnosis is efficacious in reducing musculoskeletal pain in breast cancer survivors taking aromatase inhibitors, and by doing so, whether hypnosis can help survivors to be more…
- Trial name
- NCT02657993
- Testing
- Hypnosis, Attention Control
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Asthma
Rural Asthma Effectiveness Study
The investigators will test if their intervention, Asthma Self-Management for Adolescents (ASMA), an 8-week, high school-based intervention for teenagers, improves asthma in rural high school students with uncontrolled asthma…
- Trial name
- NCT03533764
- Testing
- ASMA
- Where
- United States
- Volunteers
- 359 people
- Sponsor
- Columbia University
Urinary Tract Infections, Catheter-Related Infections
Short-course Methenamine Hippurate for Prevention of Post-operative UTI
The investigators will determine the efficacy of an innovative short regimen of methenamine hippurate on prevention of post-operative UTI in patients requiring short-term catheterization after pelvic reconstructive surgery…
- Trial name
- NO-UTI (NCT02358993)
- Testing
- methenamine hippurate, Ciprofloxacin
- Where
- 4 sites in United States
- Volunteers
- 201 people
- Sponsor
- University of Pennsylvania
Metastatic Cancer
Medico-economic Evaluation Comparing the Impact of the New Fixed-dose Nivolumab Regimen With the Old mg/kg Regimen in the Management of Patients With Metastatic Cancer
Nivolumab is a selective monoclonal antibody that binds to the Programmed cell Death 1 (PD-1) receptor and causes reduced tumor growth. It is currently approved in France in many indications.
- Trial name
- IMEPOCA (NCT05380336)
- Where
- France
- Volunteers
- 40,000 people
- Sponsor
- Nantes University Hospital
Graduate Medical Education, Cost-Effectiveness
A Brief Intervention to Improve Cost-effective Resource Use Among Medicine Housestaff
OBJECTIVE: To test a brief intervention designed to improve the cost-effectiveness of care provided by medicine housestaff for hospitalized patients.
- Trial name
- NCT01303263
- Testing
- Educational Intervention
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Brigham and Women's Hospital
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