Clinical trials: Cost-Effectiveness
Breast Cancer, Aromatase Inhibitor
Pharmacopuncture for Aromatase Inhibitor Induced Arthralgia (AIA)
This is a pragmatic pilot trial designed to compare and evaluate the efficacy, safety, and cost-effectiveness of pharmacopuncture treatment versus a control group in aromatase inhibitor-induced arthralgia patients with breast…
- Conditions
- Breast Cancer, Aromatase Inhibitor, Aromatase Inhibitor Induced Arthralgia
- Trial name
- P-ATx for AIA (NCT07789717)
- Testing
- pharmacopuncture therapy, Conventional therapy
- Where
- 3 sites in South Korea
- Volunteers
- 30 people
- Sponsor
- Ilsan Cha hospital
Healthy
Optimisation of Monitoring for Clinical Research Studies
OPTIMON will compare the efficacy and the cost of two monitoring strategies: one based on the classic standards of quality assurance, and the other one being a priori "optimized" on the main scientific and regulatory principles.
- Trial name
- OPTIMON (NCT00780091)
- Testing
- classical monitoring strategy, optimized monitoring strategy
- Where
- France
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Osteoporotic Fracture
Effectiveness or Orthopedic Intervention in Osteoporosis Management After a Fracture of the Hip With Cost-Benefit Analysis
Patients who present with fragility fractures are consistently under-evaluated and under-treated for underlying osteoporosis. This point of care represents a lost opportunity to prevent future fractures.
- Trial name
- NCT02239523
- Testing
- Letter Group, Intervention Group
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Shaare Zedek Medical Center
Heart Failure, Coronary Artery Disease
IMAGE-HF Project I-A: Cardiac Imaging in Ischemic Heart Failure (AIMI-HF)
Medical imaging is one of the fastest growing sectors in health care and increases in utilization underscore the need to ensure imaging technology is developed and used effectively.
- Conditions
- Heart Failure, Coronary Artery Disease, Ischemic Cardiomyopathy
- Trial name
- AIMI-HF (NCT01288560)
- Testing
- Advanced cardiac imaging, Standard Cardiac Imaging
- Where
- 20 sites in United States, Argentina and 3 more
- Volunteers
- 1,390 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Hypertension, Diabetes Mellitus
Cohort Study on Patient Outcomes, Effectiveness and Cost-effectiveness of Intervention Programmes for DM/HT Patients
Objectives: To determine the outcome trajectories of patients with hypertension (HT) and/or diabetes mellitus (DM), and evaluate the long-term effectiveness and cost-effectiveness of the Risk Assessment and Management Programmes…
- Conditions
- Hypertension, Diabetes Mellitus, Cardiovascular Diseases, Morbidity, Multiple
- Trial name
- TRACC (NCT04302974)
- Testing
- Different structures and processes of primary care management strategies, Multi-disciplinary Risk Factor Assessment and Management Programmes for diabetes (RAMP-DM), Multi-disciplinary Risk Factor Assessment and Management Programmes for hypertension (RAMP-HT)
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Single Lung Ventilation, Thoracic Surgery
Double-lumen Tubes (DLT) - Health Economic Study
The aim of this study is to make a health economic evaluation comparing novice physicians use of VivaSight double-lumen tube and a conventional double-lumen tube for single-lung ventilation during thoracic surgery at a teaching…
- Conditions
- Single Lung Ventilation, Thoracic Surgery, Anesthesia, Cost-effectiveness
- Trial name
- NCT03817879
- Testing
- VivaSight double-lumen tube for single-lung ventilation, Conventional double-lument tube for single-lung ventilation
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Ambu A/S
Ceserean Section, Lower Limb Fractures
Infection Prevention for "Bellwether" Surgery in Ethiopia
The study examines surgical site infections and antimicrobial resistance following life-saving surgeries like C-sections and leg fracture repairs in Ethiopia.
- Conditions
- Ceserean Section, Lower Limb Fractures, Surgical Site Infection (SSI)
- Trial name
- NCT07647796
- Testing
- Surgical Site Infection Prevention and Control (IPC) Bundle
- Where
- Ethiopia
- Volunteers
- 1,000 people
- Sponsor
- Karolinska Institutet
Anxiety Symptoms, Depressive Symptoms
Triple Aim Psychotherapy: Aimed at Improving Patient Experience, Population Health, and Cost
Community mental health programs in publically-funded jurisdictions such as Canada often have limited budgets in order to provide services, which can result in inadequate access to effective treatment for patients.
- Trial name
- TAP (NCT03659591)
- Testing
- Cognitive Behaviour Therapy, Adaptive Psychological Training
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Joseph Brant Hospital
Basal Cell Carcinoma, Optical Coherence Tomography
(Cost)-Effectiveness of Optical Coherence Tomography (OCT) in Basal Cell Carcinoma (BCC)
A multi-centre randomized non-inferiority trial investigating the (cost-)effectiveness of Optical Coherence Tomography (OCT) versus regular punch biopsy in the diagnosis and subtyping of Basal Cell Carcinoma (BCC).
- Trial name
- ROCTI (NCT03848078)
- Testing
- Optical Coherence Tomography
- Where
- Netherlands
- Volunteers
- 598 people
- Sponsor
- Maastricht University Medical Center
Back Pain, Low Back Pain
A Prospective, Multicenter, Randomized Control Study To Determine Clinical Effectiveness, Patient Wellness and Cost of Pain Related Care of In-Elastic Lumbar Sacral Orthoses Versus Standard Medical Treatment in Patients Presenting With Acute Low Back Pain In Primary Care Centers (The ARREST Study)
The objective of this study is to evaluate sixty male and non-pregnant female patients diagnosed with acute moderate to severe low back pain with the onset of symptoms within 30 days.
- Trial name
- ARREST (NCT03100097)
- Testing
- Aspen Horizon 627 LSO
- Volunteers
- 62 people
- Sponsor
- Aspen Medical Products
Solution-focused Capability, Mental Well-being
Evaluation of the School-based SIM Program in Upper Secondary School Students
The Solution-Focused Intervention for Mental Health (SIM) is a universal, school-based programme designed to promote mental well-being among adolescents.
- Conditions
- Solution-focused Capability, Mental Well-being, Mental Problems, Perceived Stress
- Trial name
- SIMRCT1 (NCT07111676)
- Testing
- The Solution-focused Intervention for Mental health (SIM)
- Where
- Sweden
- Volunteers
- 727 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Diabetes Mellitus, Hypertension
Strengthening Primary Healthcare Delivery for Diabetes and Hypertension in Eswatini
The WHO-PEN@Scale project is a three-arm cluster-randomized trial that is investigating the population-level effects of a healthcare reform in Eswatini, which aims to strengthen primary care for diabetes and hypertension.
- Trial name
- NCT04183413
- Testing
- DSD, CDP
- Where
- Eswatini
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Obsessive Compulsive Disorder (OCD)
ZeroOCD: Learn to Overcome Contamination OCD With Your Smartphone
This study is a three-arm randomized controlled trial designed to evaluate the efficacy of a smartphone-based augmented reality (AR) cognitive behavioral therapy (CBT) app, called ZeroOCD, for individuals with elevated…
- Trial name
- ZeroOCD (NCT07194473)
- Testing
- ZeroOCD, Videoconferencing CBT
- Where
- 4 sites in Belgium, Netherlands and 2 more
- Volunteers
- 189 people
- Sponsor
- VU University of Amsterdam
Renal Calculi, Nephrolithiasis
Comparison Between Different Types of Flexible Ureteroscopes
The current study aims to compare the performance of three distinct single-use digital flexible ureteroscope types in terms of cost-effectiveness, postoperative complications, operating time, and stone-free rates (SFRs).
- Trial name
- FURS (NCT07360353)
- Testing
- LithoVue™ (Boston Scientific Corporation), WiScope® (OTU Medical Inc. (Silicon Valley, USA)), Single-Use Ureterorenoscope (Scivita Medical Technology Co., Ltd.)
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Ain Shams University
Total Knee Arthroplasty
Clinical Outcomes and Cost-effectiveness Analysis of ShapeMatch Technology
The currently held belief is that total knee replacement (TKR) requires the restoration of the overall limb alignment to coincide with the mechanical limb axis.
- Trial name
- NCT01483066
- Testing
- ShapeMatch Technology
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- University of Alberta
Dental Caries
Cost-efficacy of Atraumatic Restorations (ART) Using Different Encapsulated Glass Ionomer Cement
Given the clinical damage caused by errors commonly made during the dosage and handling of glass ionomer cement (GIC) of high viscosity powder-liquid type, the use of encapsulated ionomer has been recommended for final…
- Trial name
- NCT02730000
- Testing
- ART with Equia, ART with Riva Self Cure
- Where
- Brazil
- Volunteers
- 148 people
- Sponsor
- University of Sao Paulo
Dry Eye
Acupuncture for Dry Eye
The purpose of this study is to assess whether acupuncture is more effective than artificial tear drop in the treatment of dry eye.
- Trial name
- NCT01105221
- Testing
- Acupuncture, Refresh Plus
- Where
- 3 sites in South Korea
- Volunteers
- 150 people
- Sponsor
- Korea Institute of Oriental Medicine
Myocardial Infarction, STEMI
Cost-effectiveness of Genotype Guided Treatment With Antiplatelet Drugs in STEMI Patients: Optimization of Treatment (POPular Genetics)
Rationale: the use of antiplatelet drugs (i.e. clopidogrel, ticagrelor or prasugrel) is crucial in the treatment of patients undergoing percutaneous coronary intervention (PCI) with stent implantation to prevent atherothrombotic…
- Trial name
- NCT01761786
- Testing
- CYP2C19 genotyping
- Where
- 10 sites in Belgium, Italy and 1 more
- Volunteers
- 2,700 people
- Sponsor
- Vera HM Deneer
Depressive Disorder, Major
Mindfulness Based Cognitive Therapy and Antidepressant Medication in Recurrent Depression
The purpose of this study is to investigate the (cost)effectiveness of mindfulness based cognitive therapy (MBCT) compared to that of antidepressant medication, and its combination with regard to the prevention of relapse or…
- Trial name
- NCT00928980
- Testing
- Mindfulness Based Cognitive Therapy, Optimal Medical Care
- Where
- 13 sites in Netherlands
- Volunteers
- 317 people
- Sponsor
- Radboud University Medical Center
Dental Caries
Effectiveness of Fluoride Varnish in Prevention of Dental Caries in School Children
Despite the availability of free health dental service in Sri Lanka, the prevalence and severity of dental caries among 6year old school children stand at a very high level according to the results of national oral health survey…
- Trial name
- NCT02877888
- Testing
- fluoride varnish 22600ppm
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Peradeniya
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