Clinical trials: Cost-Effectiveness
Infertility, Polyp Uterus
HYALOBARRIER® GEL ENDO Versus no HYALOBARRIER® GEL ENDO Following Operative Hysteroscopy for Improving Reproductive Outcome in Women With Intrauterine Pathology Wishing to Become Pregnant
To compare the costs and effects of HYALOBARRIER® GEL ENDO versus no HYALOBARRIER® GEL ENDO for increasing the chance of conception leading to live birth measured at 30 weeks after randomization in women wishing to become…
- Conditions
- Infertility, Polyp Uterus, Myoma;Uterus, Adhesion
- Trial name
- AGNOHSTIC (NCT03880435)
- Testing
- Hyalobarrier® gel endo
- Where
- Belgium
- Volunteers
- 419 people
- Sponsor
- University Hospital, Ghent
Intracranial Aneurysms, Wide Neck Intracranial Aneurysms
Kaneka iED Coil System for the Treatment of Wide Necked Ruptured and Unruptured Intracranial Aneurysms
This is a multi-center, prospective, propensity matched twin armed study conducted on 50 patients in the experimental arm followed for 18 months after intervention evaluating cost effectiveness, safety and efficacy of therapy.
- Trial name
- CLASS (NCT05636124)
- Testing
- Kaneka i-ED coil
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Depression, Tuberculosis
Effectiveness and Cost-Effectiveness of Depression Treatment for Individuals With TB in South Africa
This hybrid type I effectiveness-implementation trial will increase understanding of the effectiveness and cost-effectiveness of integrating a brief evidence-based treatment for major depressive disorder (MDD) within the…
- Trial name
- NCT05091580
- Testing
- Interpersonal Counseling, Enhanced treatment as usual
- Where
- South Africa
- Volunteers
- 500 people
- Sponsor
- New York State Psychiatric Institute
Heart Failure, Asthma
Economic Evaluation of Heart Failure Management in Colombian Clinics
Cost effectiveness analysis of local management of patients diagnosed with heart failure disease compared with an ideal guideline-based management.
- Trial name
- EconoHeart (NCT01084564)
- Volunteers
- 300 people
- Sponsor
- AstraZeneca
COPD, Emphysema
Implementing and Evaluating the Genie Tool in COPD
The Generating Engagement in Network Involvement (GENIE) Tool is designed to support people to find and join social activities in their own neighbourhoods.
- Trial name
- GeCop (NCT02935452)
- Testing
- GENIE - social networking tool
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Southampton
Heart Failure, Diastolic
Muscle, Essential Amino Acids, and eXercise in Heart Failure
Half of heart failure patients have preserved ejection fraction (HFpEF). Like patients with reduced ejection fraction (HFrEF), HFpEF patients suffer from exercise intolerance (low VO2max), which reduces physical function, quality…
- Trial name
- MAAX-HF (NCT03312387)
- Testing
- Exercise, Essential Amino Acids
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Arizona State University
Cancer
Effectiveness of Blended and Unguided Delivery of Mindfulness-based Cognitive Therapy for Cancer Patients
Rationale: Approximately one in three cancer patients and survivors experience significant psychological distress. Previous research has shown that mindfulness-based interventions such as mindfulness-based cognitive therapy…
- Trial name
- BUDDY (NCT05336916)
- Testing
- Buddy
- Where
- Netherlands
- Volunteers
- 254 people
- Sponsor
- Radboud University Medical Center
Physical Activity
Testing Adaptive Interventions to Improve Physical Activity for Sedentary Women
This study employs a Sequential Multiple Assignment Randomized Trial (SMART) and aims to determine the most effective adaptive intervention combining four efficacious treatments (enhanced physical activity monitor, motivational…
- Trial name
- NCT03558828
- Testing
- Step 1: PA Monitor, Step 1: PA Monitor + Text, Step 2: PA Monitor with Calls
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Hypertensive Disorders of Pregnancy (HDP), Maternal Health Care
Cost-Effectiveness of an mHealth Application in Pregnancy Care
Participants will be randomly assigned to either the intervention arm (mHealth application users) or the control arm, in which participants will record their data on paper or in Excel according to standard practice or the…
- Conditions
- Hypertensive Disorders of Pregnancy (HDP), Maternal Health Care, Mobile Health Technology (mHealth), Preeclampsia (PE)
- Trial name
- Penelope (NCT07621133)
- Testing
- mHealth application Penelope, Control
- Where
- Czechia
- Volunteers
- 166 people
- Sponsor
- Principal Engineering s.r.o.
Graves Disease
The Impact of Person Centred Care (PCC) in Grave's Disease
Mental fatigue (MF) is prevalent after Graves' disease (GD), which is the most common form of hyperthyroidism. We have reported that 38% of patients, compared to 11% of control subjects, suffer from MF more than 1 year after…
- Trial name
- NCT06309316
- Testing
- Person-centred care (PCC)
- Where
- Sweden
- Volunteers
- 220 people
- Sponsor
- Vastra Gotaland Region
Radius; Deformity, Hip Osteoarthritis
Clinical Evaluation and Cost-effectiveness Analysis of 3D Digital Surgery in Traumatology
Digital surgery, in combination with patient specific instrumentation (PSI) is being used more and more in traumatology due to its proven benefits and applications.
- Conditions
- Radius; Deformity, Hip Osteoarthritis, Hip Arthritis, Hip Arthropathy
- Trial name
- NCT06603831
- Testing
- patients treated using 3D technology and Patient-Specific Instrumentation, Patients treated with conventional surgery, without using 3D technology
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Corporacion Parc Tauli
mHealth, Eating Disorder
Evaluation of a Program for Eating Disorders That Combines Cognitive-behavioral Therapy With Online Psychological Treatment
The purpose of this project is to conduct a multicentre, randomized controlled trial (RCT) with 250 patients diagnosed with an eating disorder (ED).
- Trial name
- NCT03197519
- Testing
- TCApp, TAU
- Where
- 4 sites in Spain
- Volunteers
- 108 people
- Sponsor
- Universitat Oberta de Catalunya
Frail Elderly Syndrome, Major Surgery
Multimodal Prehabilitation for Surgery in the Elderly: a Randomised, Prospective, Multicenter, Multidisciplinary Trial
This multicentric, randomised controlled trial is to the investigators knowledge the first implementation of a multimodal, multidisciplinary prehabilitation approach using knowledge from different specialties to lower…
- Trial name
- PREHABIL (NCT04461301)
- Testing
- Multimodal Prehabilitation
- Where
- Switzerland
- Volunteers
- 466 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Breast Cancer, Colorectal Cancer
Multicenter Prospective Cohort of Informal Caregivers in Burgundy and Franche-Comté
Medical progress and modification of lifestyles have prolonged life expectancy, despite the development of chronic diseases. The support and care are often provided by a network of informal caregivers composed of family, friends…
- Conditions
- Breast Cancer, Colorectal Cancer, Prostate Cancer, Alzheimer Disease
- Trial name
- ICE (NCT02626377)
- Testing
- Support provided by social worker, Information booklet receipt
- Where
- France
- Volunteers
- 186 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Esophageal Cancer, Precancerous Condition
Endoscopy Every 2 Years or Only as Needed in Monitoring Patients With Barrett Esophagus
RATIONALE: Screening tests may help doctors find cancer cells early and plan better treatment. It is not yet known whether endoscopy every 2 years is more effective than endoscopy only as needed in finding esophageal cancer in…
- Trial name
- NCT00987857
- Testing
- 2 yearly endoscopy, comparison of screening methods, diagnostic endoscopic procedure
- Where
- United Kingdom
- Volunteers
- 3,400 people
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Type 2 Diabetes Mellitus, Periodontitis
Integrated Diabetes and Oral Health Care in Oman
Type 2 diabetes mellitus (T2DM) and periodontal (gum) disease are closely related conditions that may negatively affect each other. However, oral health is not routinely integrated into diabetes self-management education.
- Conditions
- Type 2 Diabetes Mellitus, Periodontitis, T2DM, Periodontal Disease
- Trial name
- NCT07809477
- Testing
- Health Belief Model-Based Integrated Diabetes-Oral Health Educational Intervention, Standard Diabetes Education and Routine Care
- Volunteers
- 290 people
- Sponsor
- Oman Ministry of Health
HIV, Viral Hepatitis
A Cost Effective and Time Saving Blood Test to Detect Six Human Bloodborne Infectious Diseases
The consortium will develop a new in vitro diagnostic (IVD) test to screen donated blood for bloodborne infectious pathogens, saving blood banks time and costs required for analysis of mandatory pathogens.
- Trial name
- SAFE-Blood (NCT04304612)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Montpellier
Language Discordance
Cost Effectiveness of Language Services in Hospital Emergency Departments (EDs)
Numerous studies suggest that the use of in-person, professionally trained medical interpreters can reduce health care costs associated with diagnosing and treating patients with limited English proficiency.
- Trial name
- NCT01041014
- Testing
- Professional medical interpreter
- Where
- 2 sites in United States
- Volunteers
- 447 people
- Sponsor
- Mathematica Policy Research, Inc.
Malaria
Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Mozambique
The use of insecticide-treated bed nets (ITNs) has contributed to the substantial reduction in malaria cases and deaths. This progress is threatened by increasing resistance to commonly used insecticides in important mosquito…
- Trial name
- NCT04716387
- Testing
- Standard LLIN, Piperonyl butoxide ITN, Pyriproxyfen ITN
- Where
- Mozambique
- Volunteers
- 8,726 people
- Sponsor
- PATH
Neurocutaneous Syndromes, Neurofibromatosis Type 1 (NF1)
Precision Medicine for Neurocutaneous Syndromes in Western China
The goal of this observational study (retrospective multicenter cohort study) is to learn if precision medicine approaches-including genetic testing, targeted drugs, and coordinated care from multiple specialists-can improve…
- Conditions
- Neurocutaneous Syndromes, Neurofibromatosis Type 1 (NF1), Tuberous Sclerosis Complex (TSC), Sturge-Weber Syndrome (SWS)
- Trial name
- NCT07327164
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- West China Hospital
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