Clinical trials: Cost-Effectiveness
Neoplasms, Renal Cell Carcinoma
Evaluation of the Cost and Effectiveness Sunitinib Compared to Interferon-Alfa in Finland
Patient receiving sunitinib according the clinician's independent decision as first-line treatment of advanced renal cell carcinoma (RCC) will be asked for informed consent.
- Trial name
- NCT00980213
- Testing
- sunitinib
- Where
- 5 sites in Finland
- Volunteers
- 80 people
- Sponsor
- Pirkko-Liisa Kellokumpu-Lehtinen
Tuberculosis
Effectiveness of Active Case Finding of Household Contacts in a Routine Tuberculosis (TB) Control Program
The purpose of this study is to determine the effectiveness and cost-effectiveness of a new population-based active case-finding program among adult household contacts of new infectious TB cases to detect active TB cases in the…
- Trial name
- NCT02174380
- Testing
- Active Household Contact Evaluation
- Where
- Peru
- Volunteers
- 1,900 people
- Sponsor
- Lena Shah
Aorto-iliac Aneurysm
Evaluation Of Cost-Effectiveness Of Iliac Branch Endoprostheses
The study is a multi-center, voluntary observational study on an ambispective cohort of patients treated between January 2018 and December 2025.The study aims to enroll 300 patients (around 200 patients in the retrospective…
- Trial name
- ECO-IBE (NCT07096388)
- Testing
- endovascular repair, open surgical repair
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Prof. Andrea Kahlberg
Severe Haemophilia A
Efficacy and Cost Effectiveness of Pharmacokinetic Dosing in Haemophilia A
Patients with severe Haemophilia A need prophylactic factor VIII to reduce their risk of joint and soft tissue bleeds and to prevent or reduce joint damage.
- Trial name
- NCT02697370
- Testing
- Pharmacokinetic based dosage change
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Hampshire Hospitals NHS Foundation Trust
Physical Inactivity, Healthy Aging
Cost-effectiveness and Efficacy of Different Physical Exercise Interventions (ExerMOT4Health)
Online exercise has increased in popularity during the pandemic, but there is no evidence of its feasibility and benefits in older people and the influence of motivational strategies.
- Conditions
- Physical Inactivity, Healthy Aging, Older Adult
- Trial name
- ExerMOT4Health (NCT06425679)
- Testing
- Supervised synchronous online exercise intervention without motivational strategies, Supervised synchronous online exercise intervention with motivational strategies, Supervised face to face exercise intervention without motivational strategies
- Where
- 2 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Second Degree Burn
Evaluating the Cost-effectiveness, Efficacy, Safety and Tolerance of Mepilex® Ag Versus Silvadene®
The primary objective is to compare the incremental costs (direct and indirect) and benefits (healing outcomes, quality of life) of using foam silver dressing (Mepilex® Ag) to a Silver sulfadiazine 1% cream (Silvadene®) from the…
- Trial name
- NCT00742183
- Testing
- Mepilex, Silvadene
- Where
- 10 sites in United States
- Volunteers
- 100 people
- Sponsor
- Molnlycke Health Care AB
Proximal Tibia Fracture
The Efficacy and Cost Effectiveness of Preoperative and Postoperative Cryotherapy in Proximal Tibia Fractures
Consenting patients with proximal tibia fractures will be randomized to 10 degree or 21 degree cryotherapy sleeves. Time to discharge and complications will be monitored.
- Trial name
- ARCTIC CAT (NCT01104831)
- Testing
- Cryotherapy, Room temperature cuff
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Type 1 Diabetes
Use of Continuous Glucose Monitoring Devices Among People Living With Type 1 Diabetes in Kenya.
Diabetes mellitus (diabetes) is a chronic condition that represents a major public health and clinical concern. Self-monitoring of blood glucose (SMBG) is a critical part of the care of individuals with diabetes.
- Trial name
- ACCEDE (NCT05944731)
- Testing
- Continuous glucose monitor
- Where
- Kenya
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Severe Personality Disorder
The (Cost-)Effectiveness of Generalist Versus Specialist Treatment for Severe Personality Disorders'
The goal of this clinical trial is to investigate if generalist treatment (GIT-PD) is non-inferior in improving level op personality functioning compared to specialist treatment (MBT/ST) in patients with severe personality…
- Trial name
- P-DAET (NCT06789380)
- Testing
- Schema therapy, Mentalization-based treatment, Guideline-informed treatment for personality disorders
- Where
- 5 sites in Netherlands
- Volunteers
- 358 people
- Sponsor
- Arkin
Diverticulitis
Diverticulitis: Antibiotics or Close Observation?
Rationale The prevalence of colonic diverticular disease is increasing in Western countries. Approximately 10 to 25% of patients with diverticular disease will eventually develop an episode of acute diverticulitis.
- Trial name
- DIABOLO (NCT01111253)
- Testing
- Amoxicillin-clavulanate
- Where
- 24 sites in Netherlands
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Complications Due to Heart Valve Prosthesis
Cost Effectiveness Analysis In Patients With Heart Valve Prosthesis
The combined Antiplatelet and Anticoagulant treatment decreased thrombus formation and overall mortality. Also the initiation of an efficacious early anticoagulation protocol is important because of its potential impact on the…
- Trial name
- HVP (NCT02022527)
- Testing
- Acetyl Salicylic Acid, Warfarin
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Pharmacoeconomic Unit, Egypt
Tuberculosis
Food Incentives for TB Treatment Compliance in East Timor (FITTCET)
This study will examine whether food is a cost-effective method for improving treatment compliance for TB patients in Timor Leste.
- Trial name
- NCT00192556
- Testing
- food
- Where
- Australia
- Volunteers
- 270 people
- Sponsor
- Menzies School of Health Research
HIV, Hypertension
INTEGRATE-RX: Integrating Clinical Pharmacists in HIV Care to Mitigate Last-Mile Challenges and Reduce Cardiovascular Disease Burden
The risk of heart attacks and stroke is two times higher among people living with HIV (PLWH), as compared to the general population.
- Conditions
- HIV, Hypertension, Cardiovascular Disease Prevention
- Trial name
- INTEGRATE-RX (NCT07711366)
- Testing
- INTEGRATE-RX
- Where
- 2 sites in Kenya
- Volunteers
- 450 people
- Sponsor
- Temple University
Type 2 Diabetes Mellitus
Diabetes in Europe - Prevention Using Lifestyle, Physical Activity and Nutritional Intervention in Catalonia
Public health strategy on type2 diabetes prevention in primary health care. European coordinated project (DE-PLAN) adapted to Catalonia (DE-PLAN-CAT).
- Trial name
- DE-PLAN-CAT (NCT01519505)
- Testing
- Lifestyle intervention
- Where
- Spain
- Volunteers
- 2,082 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Advanced Cardiovascular Life Support
Blended vs Conventional Training for ACLS
The investigators conducted a stratified randomized controlled trial with an embedded cost-effectiveness analysis at a tertiary hospital in China.
- Trial name
- NCT07670637
- Testing
- HeartCode ACLS Blended Learning, Instructor-Led ACLS Training
- Where
- China
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Shanghai East Hospital of Tongji University
Crohn Disease in Remission, Crohn Disease
Lengthening Adalimumab Dosing Interval in Quiescent Crohn's Disease Patients
Crohn's disease is a chronic inflammatory bowel disease. This disease can be treated with, among other things, biologicals such as adalimumab.
- Trial name
- LADI (NCT03172377)
- Testing
- Lengthening adalimumab dosing interval
- Where
- 22 sites in Netherlands
- Volunteers
- 174 people
- Sponsor
- Radboud University Medical Center
Asthma
Real-world Effectiveness and Cost-effectiveness of Leading Inhaled Corticosteroids in Asthma Management
The objective of the study was to compare the effectiveness, cost-effectiveness and direct healthcare costs of managing asthma in patients with evidence of persistent asthma, following the initiation and increased dose of inhaled…
- Trial name
- QvarAsthma (NCT01141439)
- Testing
- Extra-fine hydrofluoroalkane-beclomethasone dipropionate, Fluticasone propionate, Beclomethasone dipropionate
- Where
- United Kingdom
- Volunteers
- 815,377 people
- Sponsor
- Research in Real-Life Ltd
Frequent Attenders
Effectiveness of the "7H" Intervention to Reduce Frequent Attendance in Primary Care
The main objective is to measure the effectiveness of a new intervention to decrease use of services of primary care frequent attenders (FA).Among the secondary objectives are to evaluate the cost-effectiveness and cost utility…
- Trial name
- "7H" (NCT01151969)
- Testing
- New multicomponent "7H" intervention
- Where
- Spain
- Volunteers
- 527 people
- Sponsor
- The Mediterranean Institute for the Advance of Biotechnology and Health Research
Shyness, Wellbeing
Improving Social Anxiety Symptoms (SocWell)
The investigators will test the value of an internet self-help package (E-Couch) for alleviating social anxiety symptoms in the general population.
- Trial name
- SocWell (NCT02451878)
- Testing
- E-Couch
- Where
- 2 sites in Australia, United Kingdom
- Volunteers
- 2,105 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Critical Illness, Mechanical Ventilation
Cost-Effectiveness of Inhaled Sedation Versus Intravenous Propofol in Mechanically Ventilated Critically Ill Adults
The goal of this observational study is to learn whether inhaled sedation is a cost-effective alternative to intravenous propofol in mechanically ventilated critically ill adults admitted to the intensive care unit.
- Conditions
- Critical Illness, Mechanical Ventilation, Respiratory Insufficiency
- Trial name
- NCT07734350
- Testing
- Isoflurane, Propofol (Astra-Zeneca)
- Volunteers
- 400 people
- Sponsor
- Hospital H+ Queretaro
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