Advanced Cardiovascular Life SupportNCT07670637
Blended vs Conventional Training for ACLS
A study testing HeartCode ACLS Blended Learning and Instructor-Led ACLS Training in people with Advanced Cardiovascular Life Support, run by Shanghai East Hospital of Tongji University at 1 site in China.
Trial summary
The investigators conducted a stratified randomized controlled trial with an embedded cost-effectiveness analysis at a tertiary hospital in China. Participants were randomized to either traditional instructor-led ACLS training (ILT ACLS) or blended-learning HeartCode ACLS training (HC ACLS). Read more about this study
- Who is it for?
- Ages 22 years and olderHealthy volunteers can take part
- Conditions the study is for
- Advanced Cardiovascular Life Support
- What is being tested?
- HeartCode ACLS Blended Learning and Instructor-Led ACLS Training
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 95 participants
- Where
- 1 siteChina
- Study dates
- 1 Jul 2024to 31 Dec 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 22 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Second-year resident physicians and nurses
- Working in the emergency, critical care, or anesthesiology departments
- Valid Basic Life Support (BLS) certification
- No prior Advanced Cardiovascular Life Support (ACLS) training
- Physical ability to perform chest compressions, bag-mask ventilation, and defibrillation
- Willing and able to provide written informed consent
Who cannot join
- Individuals without a valid BLS certification
Trial locations and contacts
1 site in 1 country.
China1 site
Shanghai East Hospital Affiliated To Tongji University
Shanghai, Shanghai Municipality, 200120
About this study
Official title: Blended Learning Approach Versus Conventional Training in Advanced Cardiovascular Life Support Training: A Randomized Controlled Trial With Cost-Effectiveness Analysis
The investigators conducted a stratified randomized controlled trial with an embedded cost-effectiveness analysis at a tertiary hospital in China. Participants were randomized to either traditional instructor-led ACLS training (ILT ACLS) or blended-learning HeartCode ACLS training (HC ACLS). The primary outcome was the overall first-attempt ACLS certification pass rate. A cost-effectiveness analysis was conducted from the institutional perspective using certification pass rate as the effectiveness measure. Costs estimation included program delivery costs and productivity losses associated with participant training time.
- Conditions
- Advanced Cardiovascular Life Support
- Being tested
- HeartCode ACLS Blended Learning, Instructor-Led ACLS Training
- Keywords
- Simulation, Blended Learning, Cost-Effectiveness, Online Learning
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
HeartCode ACLS Blended LearningBehavioural
A blended-learning ACLS course combining online HeartCode self-paced modules with instructor-facilitated hands-on practice sessions.
Instructor-Led ACLS TrainingBehavioural
A traditional, entirely in-person ACLS course delivered by certified instructors, following standard American Heart Association (AHA) guidelines, without online pre-learning components.
| Study group | Role | What they receive |
|---|---|---|
| HeartCode ACLS | Experimental | Participants received blended-learning HeartCode ACLS training, which combines online self-paced modules with hands-on practice sessions. Receives: Behavioral: HeartCode ACLS Blended Learning |
| Instructor-Led ACLS Training | Active comparator | Participants received traditional instructor-led ACLS training (ILT ACLS) delivered entirely in-person by certified instructors. Receives: Behavioral: Instructor-Led ACLS Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Overall First-Attempt ACLS Certification Pass Rate
The proportion of participants who pass the ACLS certification examination on their first attempt after completing the assigned training program.
Measured: Up to 2 days.
Secondary outcomes (6)
First-Attempt Pass Rate for Individual Assessments
Proportion of participants who pass each of the three individual assessments (high-quality BLS, airway management, and Megacode) on the first attempt.
Measured: Up to 2 days.
CPR Quality - Compression Depth
Mean chest compression depth (mm) recorded during Megacode assessment, measured by high-fidelity manikin with QCPR technology.
Measured: Up to 2 days.
CPR Quality - Compression Rate
Mean chest compression rate (compressions per minute) recorded during Megacode assessment.
Measured: Up to 2 days.
CPR Quality - Chest Recoil
Proportion of compressions with adequate chest recoil (percentage) recorded during Megacode assessment.
Measured: Up to 2 days.
Training Cost per Participant
Mean total training cost per participant (in RMB), including program delivery costs (equipment, facilities, materials, personnel) and productivity losses.
Measured: Through study completion, an average of 6 months.
Participant Satisfaction
Learner satisfaction measured using the AHA ACLS Classroom Course Evaluation Form, completed immediately after course completion.
Measured: Up to 2 days.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Jun 2026
- Study start1 Jul 2024
- Primary completion31 Dec 2024
- Study completion31 Dec 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Advanced Cardiovascular Life SupportStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- This is an educational intervention study comparing two training methods.
- Masking
- None (open label)
- Enrolment
- 95 participants (actual)
Sponsor and investigators
- Lead sponsor
- Shanghai East Hospital of Tongji University
- Sponsor type
- University, hospital or other
- Collaborators
- Tongji University
- Responsible party
- Principal investigator, Min Ding, Shanghai East Hospital of Tongji University
- Investigators
- Min Ding, MMED, Principal investigator, Department of Post-Graduate Education, Shanghai East Hospital, Tongji University School of Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07670637
- Sponsor's protocol ID
- 2024YS-296
- Other IDs
- 2026-0345-YB-05
- Status last verified
- Jun 2026
- First submitted
- 16 Jun 2026
- Last updated
- 26 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data (IPD) will not be shared because the informed consent did not include provisions for data sharing. Additionally, data sharing is restricted by applicable Chinese privacy laws (Personal Information Protection Law) regarding personal performance data. Given the single-center design and moderate sample size, the generalizability of the data is limited, and the study does not involve investigational products or regulatory submission.
Study at a glance
From the registry record, last updated by the sponsor on 26 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Blended Learning Approach Versus Conventional Training in Advanced Cardiovascular Life Support Training: A Randomized Controlled Trial With Cost-Effectiveness Analysis
- ClinicalTrials.gov ID
- NCT07670637
- Acronym / sponsor ID
- 2024YS-296
- Conditions
- Advanced Cardiovascular Life Support
- Keywords
- Simulation, Blended Learning, Cost-Effectiveness, Online Learning
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 95 participants (actual)
- Lead sponsor
- Shanghai East Hospital of Tongji UniversityUniversity, hospital or other
- Collaborators
- Tongji University
- Study start
- 1 Jul 2024 (actual)
- Primary completion
- 31 Dec 2024 (actual)
- Study completion
- 31 Dec 2024 (actual)
- First posted
- 26 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The investigators conducted a stratified randomized controlled trial with an embedded cost-effectiveness analysis at a tertiary hospital in China. Participants were randomized to either traditional instructor-led ACLS training (ILT ACLS) or blended-learning HeartCode ACLS training (HC ACLS). The primary outcome was the overall first-attempt ACLS certification pass rate. A cost-effectiveness analysis was conducted from the institutional perspective using certification pass rate as the effectiveness measure. Costs estimation included program delivery costs and productivity losses associated with participant training time.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- This is an educational intervention study comparing two training methods.
| Arm | Type | Receives |
|---|---|---|
| HeartCode ACLS | Experimental | Behavioral: HeartCode ACLS Blended LearningParticipants received blended-learning HeartCode ACLS training, which combines online self-paced modules with hands-on practice sessions. |
| Instructor-Led ACLS Training | Active comparator | Behavioral: Instructor-Led ACLS TrainingParticipants received traditional instructor-led ACLS training (ILT ACLS) delivered entirely in-person by certified instructors. |
Who may qualify
- Ages
- 22 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Second-year resident physicians and nurses
- Working in the emergency, critical care, or anesthesiology departments
- Valid Basic Life Support (BLS) certification
- No prior Advanced Cardiovascular Life Support (ACLS) training
- Physical ability to perform chest compressions, bag-mask ventilation, and defibrillation
Key exclusion criteria (1 listed)
- Individuals without a valid BLS certification
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| HeartCode ACLS Blended LearningA blended-learning ACLS course combining online HeartCode self-paced modules with instructor-facilitated hands-on practice sessions. | Behavioural | HeartCode ACLS |
| Instructor-Led ACLS TrainingA traditional, entirely in-person ACLS course delivered by certified instructors, following standard American Heart Association (AHA) guidelines, without online pre-learning components. | Behavioural | Instructor-Led ACLS Training |
Primary outcome
Overall First-Attempt ACLS Certification Pass Rate
Time frame: Up to 2 days.
The proportion of participants who pass the ACLS certification examination on their first attempt after completing the assigned training program.
6 secondary outcomes
First-Attempt Pass Rate for Individual Assessments
Time frame: Up to 2 days.
CPR Quality - Compression Depth
Time frame: Up to 2 days.
CPR Quality - Compression Rate
Time frame: Up to 2 days.
CPR Quality - Chest Recoil
Time frame: Up to 2 days.
Training Cost per Participant
Time frame: Through study completion, an average of 6 months.
Participant Satisfaction
Time frame: Up to 2 days.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Jun 2026.
- Individual participant dataSharing planned: No. Individual participant data (IPD) will not be shared because the informed consent did not include provisions for data sharing. Additionally, data sharing is restricted by applicable Chinese privacy laws (Personal Information Protection Law) regarding personal performance data. Given the single-center design and moderate sample size, the generalizability of the data is limited, and the study does not involve investigational products or regulatory submission.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Min Ding, MMED principal investigator
Department of Post-Graduate Education, Shanghai East Hospital, Tongji University School of Medicine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing HeartCode ACLS Blended Learning and Instructor-Led ACLS Training in people with Advanced Cardiovascular Life Support, run by Shanghai East Hospital of Tongji University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Overall First-Attempt ACLS Certification Pass Rate (time frame: Up to 2 days.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Jun 2026.