Clinical trials: Cost-effectiveness
Migraine
Pilot Study to Compare Frovatriptan vs. Topiramate for Prevention of Migraine
Subjects enrolled at 2 investigative sites will complete 3 visits. Following Visit 1, during a 1-month Baseline Period, subjects will treat with their usual medication and document any warning signs (Prodrome pre-headache) that a…
- Trial name
- NCT00846495
- Testing
- topiramate, frovatriptan
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Clinvest
Organ Transplantation, Immunosuppressive Agents
Immunosuppressants to Postoperative Infection and Death
The goal of this observational study is to explore the different immunosuppressive agents and related outcomes in organ transplantation patients in Taiwan.
- Conditions
- Organ Transplantation, Immunosuppressive Agents, Cohort Study
- Trial name
- NCT06121804
- Testing
- Immunosuppressive Agents
- Where
- Taiwan
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Osteo Arthritis Knee
Traditional Versus Alternative Alignment in TKR
As many as 20% of patients are unhappy with the results of total knee replacement (TKR). Various changes to surgical technique have tried to address this but have not led to a significant improvement in the numbers of patients…
- Trial name
- NCT03196011
- Testing
- TKR with mechanical alignment method, TKR with alternative alignment method
- Where
- United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Atrial Fibrillation, Stroke
Systematic ECG Screening for Atrial Fibrillation Among 75 Year Old Subjects in the Region of Stockholm and Halland, Sweden
The purpose of this study is to determine whether screening for atrial fibrillation by intermittent ECG recording and initiation of anticoagulation treatment among high risk individuals is cost-effective and can lower the…
- Trial name
- NCT01593553
- Testing
- ECG screening for atrial fibrillation using intermittent ECG recorder
- Where
- Sweden
- Volunteers
- 7,173 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Hypertension, Cost Effectiveness
Cost-effectiveness of RAMP-HT for Patients With Uncontrolled Hypertension in Hong Kong
Hypertension (HT) is an important risk factor for stroke, coronary heart disease (CHD), heart failure and renal diseases, and the leading risk factor of global disease burden.
- Trial name
- NCT03301194
- Testing
- RAMP-HT
- Where
- Hong Kong
- Volunteers
- 158,322 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Type 1 Diabetes
Use of Continuous Glucose Monitoring Devices Among People Living With Type 1 Diabetes in South Africa
Diabetes mellitus (diabetes) is a chronic condition that represents a major public health and clinical concern. Self-monitoring of blood glucose (SMBG) is a critical part of the care of individuals with diabetes.
- Trial name
- ACCEDE (NCT05944718)
- Testing
- Continuous glucose monitor
- Where
- 3 sites in South Africa
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Skin Cancer
Using Technology to Scale-Up an Occupational Sun Protection Policy Program
Comprehensive approaches that combine sun protection policy and education for outdoor workers can reduce their risk for skin cancer by reducing their exposure to solar ultraviolet radiation on the job.
- Trial name
- SSW-T (NCT03278340)
- Testing
- Sun Safe Workplaces - Technology, Sun Safe Workplaces -In Person
- Where
- 2 sites in United States
- Volunteers
- 2,644 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Myopia, Hyperopia
Evaluation of Effectiveness of Correcting Refractive Error With Ready-made Spectacles
This research project will compare two methods of correcting refractive error (long or short-sightedness) with spectacle lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- RECS (NCT00657670)
- Testing
- Ready-made spectacles, Spectacles
- Where
- 2 sites in China, India
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Competencies of Midwives, Cost-benefit Analysis of Modular Training
Effect of Skill Birth Attendant Training to Improve the Competency of Service Providers
This clinical trial's primary goal is to compare birth attendants' competencies. It aims to answer the questions: Does the new modular training package enhance the competencies of skilled birth attendants? Does the competencies…
- Trial name
- NCT05866016
- Testing
- Skill birth attendant training
- Where
- 2 sites in Nepal
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ministry of Health Gandaki Province, Nepal
The Study is Focused on People With Limited Health Literacy, We Are Not Studying a Disease or Condition
(Cost)Effectiveness of the Intervention 'Gezond en Goed Met Elkaar'
The goal of this intervention study is to learn if the intervention can increase positive health and health literacy in people with limited health literacy.
- Trial name
- GGME (NCT06644547)
- Testing
- Gezond en goed met elkaar
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Mass Screening, Colorectal Cancer
SMS Messaging as a Tool to Improve Cancer Screening Programs
The aim of this project is to assess the impact on health and economics of the implementation of text messaging (SMS) in cancer screening programs. Three interventions with SMS will be evaluated through community trials.
- Conditions
- Mass Screening, Colorectal Cancer, Breast Cancer
- Trial name
- M-TICS (NCT04343950)
- Testing
- SMS reminders to enhance colorectal cancer screening, SMS reminders to return the fecal immunochemical test at the pharmacy in CRC screening:, Invitation by SMS to previous participants in breast cancer screening:
- Where
- Spain
- Volunteers
- 44,601 people, healthy volunteers welcome
- Sponsor
- Institut Català d'Oncologia
Health Services Accessibility, Rural Health
Health Ahead Comparative Effectiveness Study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening…
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services
- Trial name
- HACE (NCT07669168)
- Testing
- AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- William Brandenburg, MD
Early Mobilization, Physiotherapy
Rehabilitation of Patients From the ICU to the Post-hospital Phase
Introduction: Advances in knowledge have contributed to the increase in the number of patients who survive prolonged hospitalization in an Intensive Care Unit (ICU), and, among them, critically ill patients who develop acute…
- Conditions
- Early Mobilization, Physiotherapy, Rehabilitation
- Trial name
- NCT06405529
- Testing
- Early and intensive mobilization protocol at the ICU and Rehabilitation post-hospital discharge
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dengue Fever
Bridging Economics and Public Trust: A Study of Dengue Vaccine Cost-effectiveness and Acceptance in Thais Visiting Hospital
Study 1: Cost-effectiveness of TAK-003 Dengue Vaccination in Thailand This study aims to evaluate the cost-effectiveness of introducing the live-attenuated tetravalent dengue vaccine (TAK-003) into Thailand's national…
- Trial name
- NCT07759596
- Testing
- Objective 1- economic evaluation of Thai children with dengue vaccine
- Where
- Thailand
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Diabetes Mellitus, Hypertension
Strengthening Primary Healthcare Delivery for Diabetes and Hypertension in Eswatini
The WHO-PEN@Scale project is a three-arm cluster-randomized trial that is investigating the population-level effects of a healthcare reform in Eswatini, which aims to strengthen primary care for diabetes and hypertension.
- Trial name
- NCT04183413
- Testing
- DSD, CDP
- Where
- Eswatini
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Antenatal Depression, Antenatal Anxiety
Effectiveness and Cost-effectiveness of Simultaneous Screening and Intervention for Antenatal Depression and Anxiety Symptoms From a Transdiagnostic Perspective: A Scale-up Feasibility Study
This scale-up study aimed to explore the effectiveness of simultaneous screening and intervention of antenatal depression and anxiety in preventing postpartum depression and anxiety and how scale-up might be successfully…
- Trial name
- NCT07349368
- Testing
- implementation group
- Where
- China
- Volunteers
- 3,314 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Smoking Cessation
A Cost-effectiveness Study of Nicotine Patches Distributed Through a Quitline
The study is to understand whether distribution of two different supplies of nicotine patches through a telephone quitline has an effect on quit rates. The two different supplies are four vs.
- Trial name
- NCT01889771
- Testing
- Nicotine Patch
- Volunteers
- 1,495 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Rehabilitation, Spinal Fusion
Effect of a Case Manager to Assist the Rehabilitation for Lumbar Spinal Fusion Patients. A Randomised Controlled Trial.
The aim of the current study is to examine the effect of a case manager-assisting rehabilitation program compared to usual physical rehabilitation for patients undergoing a lumbar spinal fusion on functional disability, pain, and…
- Conditions
- Rehabilitation, Spinal Fusion, Case Managers
- Trial name
- NCT03433443
- Testing
- Case manager assisted rehabilitation, Usual physical rehabilitation
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Malaria, Soil Transmitted Helminths
Effectiveness and Cost-effectiveness of Integrated Model for Malaria and Helminth Control
Malaria remains a major health problem, especially among children living in sub-Saharan Africa where more than 90% of the disease and deaths occur.
- Conditions
- Malaria, Soil Transmitted Helminths, Schistosomiasis, Seasonal Malaria Chemoprevention
- Trial name
- MALHELMIN (NCT06182176)
- Testing
- Sulphadoxine-pyrimethamine and Amodiaquine
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Caregiver Burden, Financial Stress
CONFIDENCE Financial Education for Caregivers
The purpose of this study is to determine how feasible it is to deliver an online course to reduce out-of-pocket costs of caregiving and reduce financial stress among Latino family caregivers to a family member living with…
- Conditions
- Caregiver Burden, Financial Stress, Dementia, Alzheimer Disease
- Trial name
- CONFIDENCE (NCT05292248)
- Testing
- Confidently Navigating Financial Decisions and Enhancing Financial Wellbeing in Dementia Caregiving
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University