Clinical trials: Cost-effectiveness
Prediabetic State & High Risk Individuals on the Basis of Diabetes Risk Score
(Pakistan Diabetes Prevention Program PDPP)
The Karachi-based Pakistan Diabetes Prevention Study aims to address key issues in the prevention of type 2 diabetes. Approximately 20,000 people From four communities will be screened for diabetes risk factors using a…
- Trial name
- PDPP (NCT01530165)
- Testing
- Life style intervention
- Where
- Pakistan
- Volunteers
- 1,564 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Psychological Stress
With-Me - Technology-Aided Phone Coaching for Occupational Health Study
The purpose of this study is to examine whether the technology (web-based coaching, profiling and suggestion tool) brings added value to the traditional phone coaching in occupational health context.
- Trial name
- NCT02445950
- Testing
- Technology-aided phone wellness counselling, Phone wellness counselling
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- VTT Technical Research Centre of Finland
Orthodontic Relapse
Efficacy and Cost-effectiveness of Orthodontic Retention Protocols
Objective is to assess changes of dentition and periodontium, and hygiene in retention after the end of the active phase of orthodontic treatment, and relationship with gender, type of retention appliance, pre-therapeutic…
- Trial name
- orthoretenti (NCT05121220)
- Testing
- fixed retainer, removable retainer
- Where
- Croatia
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Poliklinika Orthonova
Physical Inactivity, Healthy Aging
Cost-effectiveness and Efficacy of Different Physical Exercise Interventions (ExerMOT4Health)
Online exercise has increased in popularity during the pandemic, but there is no evidence of its feasibility and benefits in older people and the influence of motivational strategies.
- Conditions
- Physical Inactivity, Healthy Aging, Older Adult
- Trial name
- ExerMOT4Health (NCT06425679)
- Testing
- Supervised synchronous online exercise intervention without motivational strategies, Supervised synchronous online exercise intervention with motivational strategies, Supervised face to face exercise intervention without motivational strategies
- Where
- 2 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Sexually Transmitted Infections, HIV
Multimedia WORTH With Black Drug-Involved Women on Probation
The proposed study is a randomized controlled trial (RCT) that will rigorously evaluate the effectiveness and cost-effectiveness of delivering a multimedia evidence-based intervention (WORTH) and streamlined HIV testing to…
- Conditions
- Sexually Transmitted Infections, HIV, Gonorrhea, Trichomonas
- Trial name
- E-WORTH (NCT02391233)
- Testing
- E-WORTH, Streamlined HIV Testing
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Columbia University
Older Adults
Self-administered Dual-task Training for Reducing Falls Among the Older Adults
Evidence supports that dual-task training reduces fall risk among older adults. However, the current framework for preventive care for fall prevention in Hong Kong does not include formal cognitive training, while little to no…
- Trial name
- sDTT (NCT05533333)
- Testing
- Falls prevention exercises
- Where
- Hong Kong
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Gonorrhea, Chlamydia
Adolescent Sexually Transmitted Infection Screening in the Emergency Department
Sexually transmitted infections (STIs) are highly prevalent among adolescents. Clinical practices related to screening, diagnosis, treatment, and prevention of STIs among adolescents are suboptimal.
- Trial name
- STI (NCT03715335)
- Testing
- Targeted STI Screening, Universally Offered STI Screening
- Where
- 5 sites in United States
- Volunteers
- 98,413 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Heart Failure With Preserved Ejection Fraction
PeRsonalIzed remOtely Guided Preventive exeRcIse Therapy for a healThY Heart
In the PRIORITY study, we aim to provide the clinical evidence base for the use of a new hybrid exercise intervention, which includes remotely guided home-based exercise, as an accessible, clinical and cost-effective treatment to…
- Trial name
- PRIORITY (NCT04745013)
- Testing
- PRIORITY, Usual care
- Where
- 3 sites in Belgium
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Uterine Cervical Neoplasms
Economic Evaluation of Three Populational Screening Strategies for Cervical Cancer
The aim of this study was to compare the effectiveness and the costs of three types of population interventions to increase the number of female participants in the screening programmes for cancer of the cervix carried out by…
- Trial name
- CRICERVA (NCT01373723)
- Testing
- Different alternatives to improve the coverage of the populational screening programmes of cervical cancer
- Where
- Spain
- Volunteers
- 20,994 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Malaria
Effectiveness of a Community-delivered Integrated Malaria Elimination (CIME) Model in Myanmar
In Myanmar, community health workers, known as malaria volunteers, have played a key role in reducing the malaria burden in the malaria control phase, providing essential malaria services in rural areas where the coverage of…
- Trial name
- NCT04695886
- Testing
- Community-delivered Integrated Malaria Elimination (CIME) intervention model
- Volunteers
- 6,440 people, healthy volunteers welcome
- Sponsor
- Macfarlane Burnet Institute for Medical Research and Public Health Ltd
Obstructive Sleep Apnea
Evaluation of the Cost-Effectiveness and Sensitivity of Automatic Analysis Versus Manual Analysis of Polygraphy in the Diagnosis of Obstructive Sleep Apnea.
Obstructive sleep apnea (OSA) is a chronic pathology that affects more than 20% of the adult population. It is one of the main sleep disorders with great clinical, economic and social repercussions.
- Trial name
- NCT06458777
- Testing
- poligraphy
- Where
- Spain
- Volunteers
- 3,144 people, healthy volunteers welcome
- Sponsor
- Hospital San Pedro de Logroño
Strabismus
Mobile Medical Application for Cost-effective Strabismus Screening
Develop and evaluate a new smartphone based app to screen for and measure eye misalignment (strabismus). The investigators will validate the app against simulated strabismus of known magnitude and common clinical tests.
- Trial name
- NCT03450980
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Venous Ulcers
Effect of Compressive Therapies on the Healing of Venous Ulcers
The objective of the study is to compare the effect of two treatments on the healing of venous ulcers in follow-up people in two Primary Health Services, in a city in southern Brazil.
- Trial name
- VENOS (NCT04703569)
- Testing
- Dressing with monolayer high compression elastic bandage, Dressing with Unna boot
- Where
- 3 sites in Brazil
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Malaria
Evaluation of the Public Health Impact of Seasonal Intermittent Preventive Treatment (IPT) in Children in Senegal
In areas of seasonal malaria transmission the burden of severe disease and mortality due to malaria is mainly among children under 5 years of age.
- Trial name
- NCT00712374
- Testing
- sulfadoxine-pyrimethamine plus amodiaquine
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Midwifery Continuity of Care Model, Maternal Health Outcomes
Impact of Implementing the Midwifery Model of Care on Maternal and Neonatal Health Outcomes in Ethiopia
Background: The Continuity of Midwifery Care (CoMC) is a maternity care model used in some high-income countries. In this model, a dedicated group of midwives supports women throughout pregnancy, labor, and the early postnatal…
- Conditions
- Midwifery Continuity of Care Model, Maternal Health Outcomes, Neonatal Health Outcomes, Cost Effectiveness
- Trial name
- MiMoC (NCT06854705)
- Testing
- Continuity of Midwifery care model, Standard care model
- Volunteers
- 1,654 people, healthy volunteers welcome
- Sponsor
- Debre Berhan University
Healthy Infants
Lactobacillus Reuteri DSM 17938 and Prevention of Respiratory and Gastrointestinal Infections in Mexican Infants
Randomized, doble blind, clinical, controlled trial aimed to investigate the role of Lactobacillus reuteri DSM 17938 in the prevention of gastrointestinal and respiratory tract infections in mexican children who attend day care…
- Trial name
- NCT01249911
- Testing
- Lreuteri
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- National Institute of Pediatrics, Mexico
Diverticulitis
Diverticulitis: Antibiotics or Close Observation?
Rationale The prevalence of colonic diverticular disease is increasing in Western countries. Approximately 10 to 25% of patients with diverticular disease will eventually develop an episode of acute diverticulitis.
- Trial name
- DIABOLO (NCT01111253)
- Testing
- Amoxicillin-clavulanate
- Where
- 24 sites in Netherlands
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
First Aid Training, Adolescent
PRECEDE-PROCEED BASED FIRST AID TRAINING: SELF-EFFICACY, SKILL AND COST ANALYSIS IN HIGH SCHOLL STUDENTS
This research has two objectives. Firstly, to determine the effect of a first aid training program, developed based on the PRECEDE-PROCEED model, on the first aid knowledge, self-efficacy, and skill levels of high school…
- Conditions
- First Aid Training, Adolescent, School Health
- Trial name
- NCT07770503
- Testing
- First aid training program developed based on the PRECEDE-PROCEED model., control group
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Health, Subjective, Cost Effectiveness
Effects of Patient-centered Telephone Education in Day Surgery
This study describe and evaluate the effectiveness of patient-centered telephone education in day surgery. The aim is to evaluate the effects of patient-centered telephone education on the experienced health of adult patients and…
- Trial name
- NCT03549403
- Testing
- Patient-centered telephone education
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Dementia, Mild
Trial-based Effectiveness and Cost-effectiveness of the Partner in Balance Intervention
Rationale: Informal care is one of the most important sources of care for dependent elderly people. The Partner in Balance (PIB) intervention aims to prepare and support informal caregivers for their caregiving tasks.
- Trial name
- NCT05450146
- Testing
- Partner in Balance
- Where
- Netherlands
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Maastricht University