Clinical trials: Cough, Acute
Respiratory Tract Infections
Usefulness of C-reactive Protein Testing in Acute Cough
The aim of this study is to evaluate the usefulness in Russian general practice of C-reactive protein testing in patients with acute cough or lower respiratory tract infections.
- Trial name
- NCT01794819
- Testing
- C-reactive protein test
- Where
- Russia
- Volunteers
- 179 people
- Sponsor
- Northern State Medical University
Acute Respiratory Infection
Efficacy and Safety of XC8, Film-coated Tablets, in Children With Acute Respiratory Viral Infections
The study is planned to evaluate the therapeutic efficacy and safety of XC8, film-coated tablets, in the treatment of dry non-productive cough on the background of acute respiratory infections in children from 6 to 17 years…
- Trial name
- NCT06379542
- Testing
- XC8
- Where
- 6 sites in Russia
- Volunteers
- 252 people
- Sponsor
- Valenta Pharm JSC
Respiratory Sounds
Assessment of Cough and Wheeze With Breath Sound Documenting Device
The study goal is to create a database of respiratory sounds recordings, to evaluate and validate the WIM technology and to evaluate the efficacy of a specific treatment by comparing the severity of the respiratory symptoms…
- Trial name
- NCT00711399
- Testing
- PulmoTrack® 2010 with WIM-PC™ and WIM-CC™ Technologies
- Where
- Israel
- Volunteers
- 55 people
- Sponsor
- Carmel Medical Center
Symptoms of Acute Bronchitis Accompanied by Coughing
Prospan® Hustenzäpfchen - Investigation on Efficacy and Tolerability in Children
The aims of this study are Demonstrating superior efficacy of Prospan® Hustenzäpfchen compared to Placebo in children suffering from acute bronchitis accompanied by coughing Characterisation of safety and tolerability of Prospan®…
- Trial name
- NCT01127048
- Testing
- Suppositories containing Ivy leaves dry extract
- Where
- Germany
- Volunteers
- 1,400 people
- Sponsor
- Engelhard Arzneimittel GmbH & Co.KG
Acute Bronchitis
Effectiveness of Antitussives, Anticholinergics and Honey Versus Usual Care in Adults With Acute Bronchitis.
This study, which is aimed at comparing the effectiveness of 3 symptomatic therapies (dextromethorphan, ipratropium and honey) associated with usual care and the usual care in adults with acute bronchitis, is a multicentre…
- Trial name
- AB4T (NCT03738917)
- Testing
- Dextromethorphan 15 milligrams, Ipratropium Bromide 20Micrograms Inhaler, Honey 30 g (full tablespoon)
- Where
- 12 sites in Spain
- Volunteers
- 668 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Cough
The Efficacy and Safety of Reconyl in Acute Cough Treatment
This is a 2-arm, prospective, randomized, double-blind, parallel, controlled, non-inferiority study comparing Reconyl at a dose of 225 mg three times daily and Reconyl Placebo three times daily for a 7-day course of therapy.
- Trial name
- NCT07420491
- Testing
- Reconyl
- Where
- Indonesia
- Volunteers
- 144 people
- Sponsor
- Dexa Medica Group
Chronic Obstructive Pulmonary Disease
Erdosteine (Erdotin) Versus Standard Care Plus Placebo on Erdosteine for Treatment of Cough in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
This is a parallel group, double-blind, placebo controlled, multi-centre, randomised trial. 60 patients to be included who are adult patients admitted to hospital with a clinical diagnosis of acute exacerbation of Chronic…
- Trial name
- NCT01176318
- Testing
- Erdosteine
- Where
- United Kingdom
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Acute Respiratory Distress Syndrome, Corona Virus Infection
Knowledge, Attitude and Practice of Dental Students About COVID-19
Coronavirus disease 2019 (abbreviated "COVID- 19") is a pandemic respiratory disease that is caused by a novel coronavirus and was first detected in December 2019 in Wuhan, China.
- Conditions
- Acute Respiratory Distress Syndrome, Corona Virus Infection, Acute Lung Injury, Fever
- Trial name
- NCT04449081
- Testing
- Knowledge, Attitude, Practice, Awareness, Preference
- Where
- Malaysia
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Long COVID-19 Syndrome
Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Exosomes in Treating Chronic Cough After COVID-19
This clinical trial aims to evaluate the safety and effectiveness of umbilical cord mesenchymal stem cell (UCMSC)-derived extracellular vesicle nebulization inhalation therapy for the treatment of chronic cough after COVID-19…
- Trial name
- NCT05808400
- Testing
- MSC-derived exosomes
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Huazhong University of Science and Technology
Pain, Acute, Breathing, Mouth
Combined Acupressure Effects on Post-Thoracotomy Pain and Lung Volume
Pain is a subjective, sensory and emotionally unpleasant experience resulting from real or hidden injuries in tissues. The pain experience is a subjective and unique experience in physiological and psychological terms and is the…
- Conditions
- Pain, Acute, Breathing, Mouth, Relaxation; Diaphragm, Cough
- Trial name
- NCT07411417
- Testing
- Acupressure group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Özgül Aydemir
Nasal Congestion, Cough
Study to Evaluate the Efficacy and Safety of Fixed Dose Combination of Diphenhydramine + Pseudoephedrine + Dropropizine in the Control of Cough and the Relief of Nasal Symptoms, Suffering From Non-productive Cough and Acute Rhinitis
Multicenter clinical trial, phase III, controlled by active medicine, double-blind, randomized, enroll 208 subjects, above 12 years old, that suffer acute inflammation upper airway characterized by non-productive cough…
- Trial name
- NCT01199497
- Testing
- Group 1, Group 2
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Cough
Clinical Trial of Efficacy and Safety of Levopront® 30 mg/5 ml in Patients With Dry Cough
Primary objective: To assess the efficacy of Levopront® in comparison with Libexin® based on daytime cough resolution rate by Day 8.
- Trial name
- LDP0114 (NCT03837938)
- Testing
- Levopront® syrup 30 mg/5 ml, Libexin®
- Where
- 8 sites in Russia
- Volunteers
- 184 people
- Sponsor
- Dompé Farmaceutici S.p.A
Upper Resp Tract Infection
CHAO Tos: Codeina, HederA Helix, LevOdropropizina Para la TOS
Upper respiratory tract infections affect millions globally, with cough being one of the most bothersome symptoms. While various treatments exist, their comparative effectiveness remains unclear.
- Trial name
- CHAO TOS (NCT06907355)
- Testing
- Codeine, Levodropropizine, Ivy Leaves Cough Liquid
- Where
- Chile
- Volunteers
- 196 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Acute Disease, Disease Progression
Multimodal Digital Biomarker Prediction of Acute Clinical Deterioration
Rather than relying on a single abnormal vital sign, the study will examine how multiple physiologic signals change together over time and whether changes in the relationships among these signals provide useful information about…
- Conditions
- Acute Disease, Disease Progression, Critical Illness, Biomarkers
- Trial name
- FUSION-72 (NCT07817550)
- Testing
- Multimodal Digital Biomarker Monitoring
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Truway Health, Inc.
Inflammation, Cough
Evaluation of Efficacy and Safety in Control Cough and the Relief of Nasal Symptoms in Children 2-12 Years Old,Suffering From Cough and Acute Rhinitis
Multicenter clinical trial, phase III, controlled by active medicine, open, randomized, enroll 962 children, 2 to 12 years old, that suffer acute inflammation upper airway characterized by non-productive cough, daytime/nighttime…
- Conditions
- Inflammation, Cough, Rhinitis
- Trial name
- NCT01177852
- Testing
- diphenhydramine + dropropizine + pseudoephedrine, Dropropizine and fixed dose combination of pseudoephedrine hydrochloride + brompheniramine maleate (Dimetapp® elixir).
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Chronic Obstructive Pulmonary Disease, Chronic Cough
Study of AffloVest in At-Risk Respiratory Patients During COVID-19 Pandemic
The purpose of the study is to investigate the addition of high frequency chest wall oscillation (HFCWO) therapy to the prescribed care regimen to support the diaphragm during airway clearance among post-COVID patients with COPD…
- Conditions
- Chronic Obstructive Pulmonary Disease, Chronic Cough, Covid19
- Trial name
- NCT04654481
- Testing
- HCFWO, Standard Care Plus Monitoring
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Acute Spinal Cord Injury
The Use of Functional Electrical Stimulation in Conjunction With Respiratory Muscle Training to Improve Unaided Cough in Individuals With Acute Spinal Cord Injury
The overall objective of this study is to improve unaided cough with abdominal and latissimus dorsi functional electrical stimulation in conjunction with respiratory muscle training in individuals with acute spinal cord injuries.
- Trial name
- AFES and RMT (NCT05745298)
- Testing
- Xcite Clinical Station
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Miami
Common Cold, Infections, Upper Respiratory Tract
Acute Cough Study In Children
15 mg dextromethorphan hydrobromide will be better than placebo with respect to reducing the number of coughs over 6 hours and reducing the subjective severity of cough over 6 hours.
- Trial name
- NCT01257542
- Testing
- Dextromethorphan
- Where
- 4 sites in United States
- Volunteers
- 140 people
- Sponsor
- Pfizer
Acute Respiratory Infection
Evaluating the Effect of Mucinex 1200mg on Mucociliary and Cough Clearance During an Acute Respiratory Infection
The purpose of this research study is to explore the mechanism of action of Mucinex, an oral, over-the-counter, FDA approved expectorant in patients with acute respiratory tract infections.
- Trial name
- MCC/CC (NCT01114581)
- Testing
- Mucinex
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Reckitt Benckiser LLC
Asthma Exacerbation
Treatment of Acute Asthma in ER With Combination of Systemic Steroids and Inhaled Steroids
We assume that the combination of systemic steroids and inhaled steroid in the first hour of treatment in the ER will decrease the admission rate and improve faster the pulmonary function.
- Trial name
- NCT00397267
- Testing
- inhalation of corticosteroids
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Soroka University Medical Center