Clinical trials: Coughing
Pertussis, Diphtheria
Safety and Immunogenicity of DTaP-IPV/Hib Pentavalent Vaccine in Chinese 2-month-old Infants
The main purpose of this study is to evaluate immune persistence at 30 and 36 Months of Age and Pertussis Breakthrough Infections between 19 and 36 Months of Age following two regiments of DTaP-IPV/Hib Pentavalent Vaccine in…
- Conditions
- Pertussis, Diphtheria, Tetanus, Haemophilus Influenzae Type B Infection
- Trial name
- NCT06605755
- Testing
- Different immunization regiments with DTaP-IPV/Hib Pentavalent Vaccine
- Where
- China
- Volunteers
- 785 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Common Cold, Respiratory Tract Infections
The Effect of Zinc Acetate Lozenges on the Rate of Recovery From the Common Cold
A randomized parallel-group two arm superiority trial with an allocation ratio 1:1, both participants and investigators blinded.
- Trial name
- HelZinki (NCT03309995)
- Testing
- Lozenges
- Where
- Finland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Asthma, Cough
Sensory-Mechanical Responses to Eucapneic Voluntary Hyperventilation and Mannitol
The objectives of this study are to determine the sensory-mechanical responses to Eucapneic Voluntary Hyperventilation (EVH) and Mannitol in individuals with cough variant asthma (CVA) and methacholine-induced cough with normal…
- Conditions
- Asthma, Cough, Cough Variant Asthma
- Trial name
- NCT03105843
- Testing
- Methacholine (MCh) Challenge Testing, Eucapneic Voluntary Hyperventilation (EVH), Mannitol Inhalation Kit
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Dr. Diane Lougheed
Cough
Respiratory Kinematics During Voluntary and Reflex Cough in Healthy Adults
Cough is a defensive behavior that involves three stages. A large inspiratory phase, a compression phase where the vocal folds close and subglottal pressure is developed, and an expiratory phase.
- Trial name
- NCT01854268
- Testing
- Healthy adults who receive capsaicin
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Florida
Bacterial Infections, Virus Diseases
Safety, Tolerability, and Immunogenicity of V419 in Healthy Infants When Given at 2, 4, and 11 to 12 Months (V419-008)
This study will determine whether participants who receive V419 (PR5I) at 2, 4, and 11 to 12 months of age have an acceptable response to the vaccine.
- Trial name
- NCT01480258
- Testing
- PR5I, Rotavirus vaccine, Prevenar 13™
- Volunteers
- 1,315 people, healthy volunteers welcome
- Sponsor
- MCM Vaccines B.V.
Diphtheria, Pertussis
Booster Study of Combined Diphtheria-tetanus-acellular Pertussis Vaccine in Healthy Adults
The aim of the study is to assess the safety and immunogenicity of GlaxoSmithKline Biologicals' (formerly known as SmithKline Beecham Biologicals) combined diphtheria-tetanus-acellular pertussis vaccine in healthy adults, from…
- Conditions
- Diphtheria, Pertussis, Tetanus
- Trial name
- NCT01267058
- Testing
- GSK Biologicals' combined diphtheria, tetanus, acellular pertussis vaccine, GSK Biologicals' acellular pertussis vaccine, Commonwealth Serum Laboratories' combined diphtheria and tetanus vaccine
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Cough
Neurophysiology and Pharmacology of Cough Reflex Hypersensitivity
A cough lasting more than 2 months is known as a chronic cough, affecting 12-23% of the adult non-smoking population. Chronic cough has many associated complications including incontinence, muscular chest pains, blackouts and…
- Trial name
- NCT00858624
- Testing
- ketamine
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jacky Smith