Clinical trials: Coughing on Induction
General Anesthetic Drug Adverse Reaction
Effect of Tegileridine Versus Sufentanil as Analgesic Components on Opioid-Induced Cough During Anesthesia Induction
In patients undergoing general anesthesia with planned tracheal intubation , a prospective, randomized, controlled study was conducted to record the occurrence of cough 2 minutes after injection of Sufentanil or Tegilerdine.
- Trial name
- NCT07323043
- Testing
- Tegilerdine, Sufentanil
- Where
- China
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Lianyungang
Rhinitis
A Study to Investigate the Effect of SB-705498 on Chronic Cough
This study is designed to loook at the affect of oral SB-705498 on cough following an inhaled capsaicin challenge
- Trial name
- NCT01476098
- Testing
- SB-705498
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- GlaxoSmithKline
Coughing on Induction, Vapors; Inhalation
Two Different Preparations of Sevoflurane in Induction
In our study we aim to study the effects of two preparations of Sevoflurane in vital capacity rapid inhalation induction.
- Trial name
- NCT01792063
- Testing
- Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Istanbul University
Fentanyl-induced Coughing
The Effect of Priming Intravenous Rocuronium on Fentanyl-Induced Coughing
An intravenous bolus of fentanyl often induces a cough reflex. This study investigates whether priming with rocuronium can attenuate fentanyl-induced coughing effectively.
- Trial name
- NCT01532466
- Testing
- Rocuronium
- Where
- Taiwan
- Volunteers
- 260 people
- Sponsor
- Taichung Armed Forces General Hospital
Nonasthmatic Eosinophilic Bronchitis
Efficacy and Safety of add-on Montelukast to Inhaled Budesonide in the Treatment of Nonasthmatic Eosinophilic Bronchitis
Hypothesis: Add-on therapy with oral montelukast (Mon) to inhaled budesonide (BUD) may achieve better control of cough caused by nonasthmatic eosinophilic bronchitis (NAEB) with faster reduction of airway eosinophilia.
- Trial name
- NAEB (NCT01121016)
- Testing
- Montelukast
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Guangzhou Medical University
Surgery, Anesthesia
A Comparison of Desflurane vs. Sevoflurane and the Time to Awakening and the Incidence and Severity of Cough
Goals for ambulatory surgery include providing optimal surgical conditions while ensuring a rapid early recovery without side effect.
- Trial name
- NCT01202162
- Testing
- Desflurane, Administration of Sevoflurane
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Northwestern University
Fentanyl-induced Cough
Effects of Different Doses of Dexmedetomidine on Fentanyl-induced Cough
The investigators aimed to investigate the effects of pretreatment with different doses of dexmedetomidine on the cough caused by fentanyl during anesthetic induction.
- Trial name
- NCT03126422
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Cough
The Effects of Salbutamol on Mannitol Induced Cough Responses in Healthy Controls
The study aim is to investigate if changes in osmolarity using mannitol challenge can evoke coughing healthy controls with no evidence of bronchoconstriction (PC20>16mg/ml or mannitol PD15 > 635 mg, or < 10% incremental fall in…
- Trial name
- COMA (NCT04565847)
- Testing
- Salbutamol 5mg/mL, Sodium Chloride 0.9% Inhl 3Ml
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Airway Extubation
Maximum Expiratory Pressure in Induced Cough as a Predictor of Extubation Failure
Clinical trial for the evaluation of diagnostic tests. The sample was composed of adults under mechanical ventilation who passed the spontaneous breathing trial and was ready to be extubated.
- Trial name
- NCT04356625
- Testing
- MEPic
- Where
- Argentina
- Volunteers
- 80 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas
Cough, Lidocaine
The Effect of Lidocaine on Smooth Emergence With Double Lumen Tube
Cough suppression during emergence and tracheal extubation from general anaesthesia has become an important issue as part of patient safety.
- Trial name
- NCT04455711
- Testing
- Lidocaine Iv, Remifentanil
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Ajou University School of Medicine
Cough
Effect of Magnesium on Remifentanil Induced Cough
The hypothesis of this study is that Magnesium sulfate pretreatment (50mg/kg) will reduce the incidence of cough and chest wall rigidity caused by remifentanil administration.
- Trial name
- NCT05237791
- Testing
- Magnesium sulfate
- Volunteers
- 78 people
- Sponsor
- Seoul National University Bundang Hospital
Acute Cough
Study of Gefapixant (MK-7264) in Acute Cough for Participants With Induced Viral Upper Respiratory Tract Infection (URTI) (MK-7264-013)
The purpose of the study is to evaluate the efficacy, safety, and tolerability of gefapixant (MK-7264) in adult participants with induced viral upper respiratory tract infections (URTI).
- Trial name
- NCT03569033
- Testing
- Gefapixant
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC