Clinical trials: Couples
Infertility, Vaginal Flora Imbalance
Evaluate the Use of a New Probiotic Strain in Couples With Fertility Problems and Dysbiosis.
Pilot study to evaluate the effect of the strain Lactobacillus PS11610 on the microbiota of the female and male genital tract in couples with fertility problems.
- Conditions
- Infertility, Vaginal Flora Imbalance, Genital Disorder
- Trial name
- PROFEC (NCT03701893)
- Testing
- Lactobacillus PS11610
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ProbiSearch SL
Cancer Diagnosis, Couples
Cancer Survivors and Their Romantic Partners' Preferences for a Couples-based Physical Activity
The goal of this research is to explore cancer survivors' and their romantic partners' interest in a couples-based physical activity intervention and whether cancer-specific exercise education influences exercise beliefs and…
- Trial name
- NCT04471363
- Testing
- Cancer-Specific Exercise education
- Where
- United States
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Drug Abuse
Behavioral Couples Therapy for Female Drug-Abusing Patients
In treating drug addiction, many studies of male patients show Behavioral Couples Therapy (BCT) helps the whole family (the drug abuser, the relationship partner, and their children) and is more effective than typical individual…
- Trial name
- CPW-D (NCT01189305)
- Testing
- Behavioral Couples Therapy, Individual Drug Counseling
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Harvard University
HIV/AIDS
LetSync: Pilot Test of Mobile Health (mHealth) Intervention
The Pilot Test (AKA Study B) will entail a pilot randomized, controlled trial (RCT) of an mHealth behavioral intervention, LetSync, with 80 couples (N=160) to assess its acceptability, feasibility, and preliminary impact on…
- Trial name
- NCT04951544
- Testing
- LetSync app
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment
Couples Therapy to Enhance Intimacy Between Patients With Advanced or Recurrent Prostate Cancer and Their Partners
RATIONALE: A couples therapy program may enhance intimacy and reduce psychological distress in patients with prostate cancer and in their partners.
- Conditions
- Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment, Sexual Dysfunction, Sexuality and Reproductive Issues
- Trial name
- NCT00483678
- Testing
- counseling intervention, questionnaire administration, psychosocial assessment and care
- Where
- 2 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Depression, Couples (Persons)
Social Interaction and Compassion in Depression
The purpose of this study is to determine how a CBCT® (Cognitively Based Compassion-Training) for couples affect aspects of health and especially social interactions in depressed female patients and their romantic partners.
- Trial name
- SIDE (NCT03080025)
- Testing
- CBCT® (Cognitively Based Compassion-Training)
- Where
- Germany
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Stroke, Depression, Anxiety
Promoting Resilience in Stroke Survivor-carepartner Dyads (ReStoreD)
Affecting nearly 800,000 people in the US every year, stroke is a leading cause of long-term disability, and has serious consequences for stroke survivors and their carepartners.
- Conditions
- Stroke, Depression, Anxiety, Coping Skills, Couples
- Trial name
- ReStoreD (NCT04845542)
- Testing
- ReStoreD
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Utah
Sleep Problems, Psychological
Evaluation of a Couple-based Psycho-socio-educational Intervention Using WeChat/WhatsApp on Dyadic Psychological and Sleep Outcomes
Background: Pregnancy is a challenging time, and couples frequently experience psychological and sleep problems. Despite the dyadic effects of these problems, most interventions have focused on pregnant women alone, not on…
- Conditions
- Sleep Problems, Psychological, Well-Being, Psychological
- Trial name
- WeLove RCT (NCT07736378)
- Testing
- Couple-based psycho-socio-educational intervention using WeChat/WhatsApp
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
HIV Infections, Hiv
Acceptability, Feasibility, and Preliminary Impact of a Web-based, HIV Prevention Toolkit With Cisgender Male Couples in Lima, Peru
This digital couples-based HIV/STI prevention intervention project will determine preliminary efficacy to improve uptake of evidence-based strategies and a tailored prevention plan among cisgender male couples who are in a…
- Conditions
- HIV Infections, Hiv, Sexually Transmitted Infections (Not HIV or Hepatitis), Sexually Transmitted Diseases
- Trial name
- NCT05873855
- Testing
- Para ti, para mi, para nosotros (P3), Waitlist Control Para ti, para mi, para nosotros (P3)
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Florida International University
HIV
We-INtervention Among Chinese HIV-serodiscordant Male Couples
HIV-serodiscordant male couples, in which one male partner is HIV-seropositive and the other is HIV-seronegative, experience multiple risks in HIV care and prevention.
- Trial name
- NCT06639932
- Testing
- We-INtervention, Usual Care Group
- Where
- 4 sites in China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- City University of Hong Kong
Perinatal
Study on the Fetal Safety of New Coronavirus Vaccination for Couples During the Peri-pregnancy Period
All the pregnant women and newborns of both or one of the couples who gave birth in Ditan hospital were collected as the observation group, and the pregnant women and newborns of both husband and wife who gave birth in our…
- Trial name
- NCT05125770
- Testing
- New crown vaccine
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Ditan Hospital
Knowledge, Attitudes, Practice
Assessment of Knowledge, Attitude and Practice of Eligible Couples Regarding Eugenics
A Descriptive study to assess the knowledge, attitude and practice regarding eugenics among eligible couples of selected area of Ambala, Haryana, India.
- Trial name
- NCT03237559
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Prostate Cancer Patients, Sexual Dysfunctions
Dyadic STEP-SexPCare for Sexual Health in Chinese Prostate Cancer Survivors and Their Female Partners
This pilot feasibility randomized controlled trial will evaluate the feasibility, acceptability, safety, and preliminary effects of Dyadic STEP-SexPCare, a culturally tailored, nurse-led psychosexual programme for Hong Kong…
- Trial name
- STEP-SexPCare (NCT07829367)
- Testing
- Dyadic STEP-SexPCare, Standard Survivorship Care
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Relational Problems, Couples
The Effects of Relational Letter Writing
The main objective of this research is to explore the relational letter writing technique as an intervention for improving couples' relational well-being. This is a two-arm superiority randomized clinical trial.
- Trial name
- NCT05194683
- Testing
- Relational Letter Writing
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universitat Oberta de Catalunya
Pregnancy, Postpartum Period
The Effect of Sexual Education-Counseling According to PLISSIT Model of Couples' Sexual Functions During Pregnancy and Postpartum
Sexuality is a natural part of human life at every stage of life. It is a multidimensional phenomenon influenced by biological, psychological, social, interpersonal and cultural factors.
- Conditions
- Pregnancy, Postpartum Period, Sexual Dysfunction, PLISSIT Model
- Trial name
- NCT06762301
- Testing
- sexual education and counseling, Routine clinical care
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
HIV Infections
Partners PrEP Program
Through close collaboration with the Ugandan Ministry of Health, the investigators plan to provide PrEP for HIV-negative members of HIV serodiscordant couples by launching PrEP delivery within 12 public ART clinics in Kampala…
- Trial name
- PPP (NCT03586128)
- Testing
- PrEP, ART
- Where
- Uganda
- Volunteers
- 1,381 people, healthy volunteers welcome
- Sponsor
- University of Washington
Stroke, Depression
Testing a Positive Psychology-based Intervention for Couples Coping With Stroke
This study aims to pilot test an 8-week, self-administered dyadic (couples-based) positive psychology intervention for couples coping with stroke using a randomized, waitlist control design.
- Conditions
- Stroke, Depression, Depressive Symptoms, Post-stroke Depression
- Trial name
- RESToreD (NCT03335358)
- Testing
- Dyadic (couples-based) positive psychology intervention
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Utah
Family Conflict, Internet-Based Intervention
Love Together, Parent Together: A Feasibility Study
The COVID-19 pandemic has introduced additional stressors and challenges to couples' relationships, with potential ripple effects across all family subsystems and child adjustment.
- Trial name
- L2P2 (NCT05143437)
- Testing
- Love Together Parent Together
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- York University
Partner HIV Testing, Couple HIV Counseling
Couple-oriented Prenatal HIV Counseling in Low and Medium HIV Prevalence Countries
ANRS 12127 Prenahtest is an intervention trial conducted in four countries (Cameroon, Dominican Republic, Georgia and India), where pregnant women are randomized during prenatal care to receive either standard post-test HIV…
- Conditions
- Partner HIV Testing, Couple HIV Counseling, Couple Communication, HIV Incidence
- Trial name
- Prenahtest (NCT01494961)
- Testing
- Couple-oriented post-test HIV counseling
- Where
- 4 sites in Cameroon, Dominican Republic and 2 more
- Volunteers
- 1,943 people, healthy volunteers welcome
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
Relationships, Marital
5 Verbs for Couples - Pilot Study
The current research is designed to implement and evaluate 5 Verbs for Couples, a new relationship education program that can be completed individually or by both partners together.
- Trial name
- NCT07352670
- Testing
- 5 Verbs for Couples
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign