Clinical trials: Covid-19 Patients
COVID-19, Hypertension
Hypertension in Patients Hospitalized With COVID-19
Some studies have shown that the main pathogenesis of patients with covid19 is related to ACE2 receptor. Lung is one of the main organs, and there are many ACE2 receptors in cardiovascular system.
- Trial name
- HT-COVID19 (NCT04318301)
- Where
- China
- Volunteers
- 275 people
- Sponsor
- Zhenhua Zen
COVID-19
Critically Ill Patients With COVID-19 in Hong Kong: a Multicentre Observational Cohort Study
The purpose of this case series is to describe the characteristics, organ dysfunction and support and 2 week outcomes of critically ill patients with nCov infection.
- Trial name
- NCT04285801
- Where
- 3 sites in Hong Kong
- Volunteers
- 8 people
- Sponsor
- Chinese University of Hong Kong
Covid19, COVID19 Infection
State of Oxygen Metabolism, Cardiovascular and Respiratory System Reserve Capacity in Patients Who Underwent COVID-19
This clinical study will create an evidence base for rehabilitation approach, which will be used for restoration of pulmonary ventilation and gas exchange, increase of tolerance to physical load reduced in patients who underwent…
- Trial name
- NCT05911100
- Testing
- Spirography and assessment of pulmonary diffusion capacity, Cardiopulmonary stress test, Computed tomography of the chest organs
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Safety Issues
The Safety of Paxlovid in Hemodialysis Patients With Covid-19
Infection with SARS-CoV-2 continue to threaten global health. Persons with chronic kidney disease, including dialysis treatment are at hight risk for severe Covid-19 and associated adverse outcomes.
- Trial name
- SPHPS (NCT05366192)
- Testing
- Nirmatrelvir and ritonavir stage 1, Nirmatrelvir and ritonavir stage 2
- Where
- China
- Volunteers
- 18 people
- Sponsor
- RenJi Hospital
COVID-19
Mortality, Gravity Predictive Factors and Clinical Evolution of Older COVID-19 Patients in Short Geriatric Services.
Since the beginning of the year 2020, clinical characteristics of a new disease as the global COVID-19 epidemic has spread in France.
- Trial name
- GERICOVID (NCT05455892)
- Testing
- Clinical data collection during hospitalization in short geriatric units.
- Where
- 5 sites in France
- Volunteers
- 450 people
- Sponsor
- Hospices Civils de Lyon
Covid19
COVID-19 Citizen Science Expansion Project
COVID-19 Citizen Science (CCS), launched in March 2020, supports collaborative research on symptoms, risk factors, surveillance, biomarkers and testing for COVID-19 using the Eureka Research Platform.
- Trial name
- NCT05548803
- Where
- 9 sites in United States
- Volunteers
- 52,351 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
covid19
Evaluation of the Efficacy of Mouth Rinses With Commercial Mouthwashes to Decrease Viral Load in Saliva in COVID-19 Patients
As no curative treatment for SARS-CoV-2 is currently available, most public health measures to contain the pandemic are based on preventing the spread of the pathogen.
- Trial name
- NCT05543603
- Testing
- Lacer Clorhexidina Colutorio, Lacer Clorhexidine 0.20% Colutorio, Gingilacer Encías Delicadas Colutorio
- Where
- 4 sites in Spain
- Volunteers
- 48 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
COVID-19
Infliximab in the Treatment of Patients With Severe COVID-19 Disease
In this trial, patients that are severely affected by the disease COVID-19 will either receive infliximab, an anti-inflammatory drug, or standard therapy.
- Trial name
- INFLIXCOVID (NCT04922827)
- Testing
- Infliximab, Standard of Care
- Where
- 4 sites in Germany
- Volunteers
- 9 people
- Sponsor
- Jena University Hospital
Microbiome,Immune Function, Critically Ill
Microecology and Host Immunity in Patients With Severe COVID-19 Infection
The purpose of this study was to analyze the relationship between the microbial community, host immunity and the prognosis of patients with severe COVID-19.
- Trial name
- NCT05670275
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
COVID-19 Pneumonia
Pirfenidone in Adult Hospitalized Patients With COVID-19
This center intends to conduct a multicenter, randomized, placebo-controlled study to evaluate the effectiveness and safety of Nintedanib ethanesulfonate soft capsule in the treatment of pulmonary fibrosis in patients with…
- Trial name
- NCT05713292
- Testing
- Pirfenidone Oral Product
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Capital Medical University
Sars-CoV2, Cancer
Prospective Analysis of Morbi-mortality of Patients With Cancers in Active Phase of Treatment Suspected or Diagnosed of a SARS-CoV-2 Infection
National multicentre epidemiological study to describe retrospectively and prospectively the clinical outcomes of patients with a suspected coronavirus infection (either confirmed or not) while receiving a medical treatment for…
- Trial name
- ONCOVID-19 (NCT04363632)
- Where
- 18 sites in France
- Volunteers
- 1,231 people
- Sponsor
- Centre Leon Berard
COVID-19, Dysglycemia
Can Intensive Insulin Therapy Improve Outcomes of COVID-19 Patients
Evaluation of the reciprocal relation between hyperglycemia/diabetes mellitus (HG/DM) and COVID-19 disease and the effect of mode of insulin therapy; intensive (IIT) or conventional (CIT) on patients' outcomes All patients…
- Trial name
- NCT05441631
- Testing
- Insulin, Subcutaneous Insulin
- Where
- Egypt
- Volunteers
- 436 people
- Sponsor
- Benha University
COVID-19
Platelet Aggregation in COVID-19 Patients
Context: Hypercoagulable state associated with COVID-19 is one of the pathologic events that noticed in different waves of COVID-19 pandemics and leads to serious consequences in mortality and morbidity Aim: To evaluate platelet…
- Trial name
- NCT06097429
- Testing
- blood sample for platelet aggregation
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Covid-19 Patients
Cupping Therapy on Immune System in Post Covid -19
Purpose of this study is to investigate 1. The effect of Dry cupping therapy on T-Lymphocyte in post covid-19 patients. 2. The effect of Dry cupping therapy on serum Cytokine in post covid-19 patients. 3.
- Trial name
- NCT05901337
- Testing
- Cupping therapy with convential medical treatment, Convential medical treatment
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Cairo University
Covid19
Study of F-652 (IL-22:IgG2 Fusion Protein) in Patients With Moderate to Severe COVID-19
This is an interventional, multicenter, 2-arm, parallel-group, randomized, double-blind, placebo controlled, dose-escalation, safety and efficacy study of F-652 treatment versus placebo in patients aged 18 years or older with a…
- Trial name
- NCT04498377
- Testing
- F-652
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- EVIVE Biotechnology
COVID
Become of Patients Infected or Suspected of Being Infected by Covid-19 and Supported by the GHPSJ and the Establishments of the Paris Plaisance Hospital City
The ongoing Coronavirus (Covid-19) pandemic is causing a major global health crisis and is shaking up hospital organizations. To date, the recognized risk factors for severe forms of Covid-19 infection are elderly patients (> 70…
- Trial name
- COVIDGHPSJCite (NCT04365530)
- Where
- 5 sites in France
- Volunteers
- 3,767 people
- Sponsor
- Fondation Hôpital Saint-Joseph
SARS-CoV-2 Acute Respiratory Disease, Covid19
Pandemic Triage Score in Patients With Known or Suspected Severe Acute Respiratory Syndrome (SARS) CoronaVirus (CoV) 2 Infection
During this pandemic period, the goal of the health care system is to optimize the use of intensive care services for patients infected with SARS-CoV-2, given the frequency of complications that can lead to high mortality.
- Trial name
- STC-19 (NCT04371471)
- Testing
- STC-19 score
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Conscious Sedation, Pathologic Processes
Prospective Electroencephalography Evaluation of Sedation in COVID-19
Sedation of severe COVID-19 disease are often complicated. We try to find a correlate for this observation by encephalographic studies.
- Conditions
- Conscious Sedation, Pathologic Processes, Electroencephalogram, Acute Respiratory Distress Syndrome
- Trial name
- NCT04815109
- Testing
- Encephalography measurement
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Goethe University
Covid19
Comparison of Remdesivir Versus Lopinavir/ Ritonavir and Remdesivir Combination in COVID-19 Patients
Comparison outcomes of a large cohort of moderate and severe COVID-19 patients received remdesivir alone with patients who received remdesivir in combination with lopinavir/ ritonavir in addition to standard management.
- Trial name
- NCT04738045
- Testing
- Remdesivir, Lopinavir/ Ritonavir and Remdesivir combination
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ahmed Essam
ARDS, Hypoxemia
Almitrine in COVID-19 Patients With ARDS Treated by HFNO
The purpose of this study is to determine the effects of Almitrine administration on oxygenation in COVID-19 patients with acute respiratory distress syndrome treated by high-flow nasal canula oxygen therapy as first-line…
- Trial name
- NCT05216575
- Testing
- Administration of Almitrine
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
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